Synthesis of pyranopyrazolo N-glycoside and pyrazolopyranopyrimidine C-glycoside derivatives as promising antitumor and antimicrobial agents by Hafez Hend N., El-Gazzar Abdel-Rhman B. A.

Subjects: “…n-nucleoside of pyranopyrazole…”
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Chronic hepatitis B and risk of kidney involvement by M. V. Mayevskaya, I. N. Tikhonov, V. T. Ivashkin

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Predictors of HBsAg seroclearance in HBeAg-negative chronic hepatitis B patients treated with nucleotide analogs plus polyethylene glycol interferon by Yan Peng, Mingzhe Ma, Ting Liu, Wenmin He, Shutao Lin, Wa Zhong, Xiaohui Min

Subjects: “…nucleoside analogs…”
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D-ribose-5-phosphate inactivates YAP and functions as a metabolic checkpoint by Cheng-E Tu, Yong-Feng Liu, Hong-Wei Liu, Chun-Mei Jiao, Quentin Liu, Mien-Chie Hung, Peng Li, Xiang-Bo Wan, Xin-Juan Fan, Yun-Long Wang

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Use of Nucleic Acid Analogs for the Study of Nucleic Acid Interactions by Shu-ichi Nakano, Masayuki Fujii, Naoki Sugimoto

“…Unnatural nucleosides have been explored to expand the properties and the applications of oligonucleotides. …”
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NupR Is Involved in the Control of PlcR: A Pleiotropic Regulator of Extracellular Virulence Factors by Jiaxin Qin, Ziqi Wang, Cheng Qian, Guohui Ji, Yizhuo Zhang, Zhanglei Cao, Bing Yan, Jun Cai

“…NupR is a nucleoside permease regulator belonging to the GntR family, mainly regulating nucleoside transport in <i>Bacillus thuringiensis</i>. …”
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Small Bowel Review - Part I by ABR Thomson, G Wild

“…Part I of this two-part review of the small bowel examines carbohydrates, including brush border membrane hydrolysis and sugar transport; amino acids, dipeptides, proteins and food allergy, with a focus on glutamine, peptides and macromolecules, and nucleosides, nucleotides and polyamines; salt and water absorption, and diarrhea, including antidiarrheal therapy and oral rehydration treatment; lipids (digestion and absorption, fatty acid binding proteins, intracellular metabolism, lipoproteins and bile acids); and metals (eg, iron) and vitamins.…”
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Black Trumpet, Craterellus cornucopioides (L.) Pers.: Culinary Mushroom with Angiotensin Converting Enzyme Inhibitory and Cytotoxic Activity by Jelena Radović, Aleksandra Leković, Ana Tačić, Margarita Dodevska, Tatjana Stanojković, Tijana Marinković, Čedomir Jelić, Tatjana Kundakovic-Vasović

“…The content of essential and non-essential free amino acids was 1.49 and 5.48 mg/g dry weight (dw). The nucleosides and 5’-nucleotides were determined at 1.84 and 3.99 mg/g dw, respectively. …”
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tRNA Modification and Genetic Code Variations in Animal Mitochondria by Kimitsuna Watanabe, Shin-ichi Yokobori

“…This review aims to clarify the structural relationship between these nonuniversal codons and the corresponding tRNA anticodons including modified nucleosides and to speculate on the possible mechanisms for explaining the evolutional changes of these nonuniversal codons in the course of animal evolution.…”
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The Impact of Purinergic System Enzymes on Noncommunicable, Neurological, and Degenerative Diseases by Margarete Dulce Bagatini, Alessandra Antunes dos Santos, Andréia Machado Cardoso, Aline Mânica, Cristina Ruedell Reschke, Fabiano Barbosa Carvalho

“…These pathological conditions can be associated with disturbance in the signaling mediated by nucleotides and nucleosides of adenine, in expression or activity of extracellular ectonucleotidases and in activation of P2X and P2Y receptors. …”
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Ways to promote the efficiency of herpetic stomatitis treatment by R.V. Lutsenko, N.V. Moisieieva, A.H. Sydorenko, H.Yu. Ostrovska, A.A. Kapustianska

“…Applying inosine pranobex in the combination therapy of herpetic stomatitis has shown a potent clinical efficacy and can be an alternatіve to acyclic nucleosides in patients with herpetic stomatitis of the oral mucosa.…”
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The protective effect and crucial biological pathways analysis of Trametes lactinea mycelium polysaccharides on acute alcoholic liver injury in mice based on transcriptomics and me... by Jinbin Hao, Liyun Ye, Guoliang Meng, Yanjiao Song, Junsheng Fu, Xiaoping Wu

“…The metabolome analysis revealed that TLMPS significantly regulated specific metabolites in the liver, including organic acids, lipids, nucleosides, and organic oxygen compounds. KEGG enrichment analysis revealed the significant involvement of different metabolites in choline metabolism, ATP-binding cassette transporters, and glycerophospholipid metabolism. …”
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Gut microbiota modulation in cardiac cell therapy with immunosuppression in a nonhuman primate ischemia/reperfusion model by Hung-Chih Chen, Yu-Che Cheng, Marvin L. Hsieh, Po-Ju Lin, Emily F. Wissel, Theodore Steward, Cindy M. C. Chang, Jennifer Coonen, Timothy A. Hacker, Timothy J. Kamp, Patrick C. H. Hsieh

“…Immunosuppression promoted anaerobes, such as Faecalibacterium, Streptococcus, Anaerovibrio and Dialister, and altered amino acid metabolism and nucleosides/nucleotides biosynthesis in host plasma. …”
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Decoding the general role of tRNA queuosine modification in eukaryotes by Jorge Díaz-Rullo, Luis González-Moreno, Araceli Del Arco, José Eduardo González-Pastor

“…Abstract Transfer RNA (tRNA) contains modified nucleosides essential for modulating protein translation. …”
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Synthesis of Specifically Modified Oligonucleotides for Application in Structural and Functional Analysis of RNA by Nico Rublack, Hien Nguyen, Bettina Appel, Danilo Springstubbe, Denise Strohbach, Sabine Müller

“…In particular, we report on the synthesis of 5′-O-dimethoxytrityl-2′-O-tert-butyldimethylsilyl protected 3′-O-phosphoramidites of nucleosides that carry amino linkers of different lengths and flexibility at the heterocyclic base, their incorporation in a variety of RNAs, and postsynthetic conjugation with fluorescent dyes and nitroxide spin labels. …”
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Chick Early Amniotic Fluid Alleviates Dextran-Sulfate-Sodium-Induced Colitis in Mice via T-Cell Receptor Pathway by Fan Chen, Yining Zhao, Yanfa Dai, Ning Sun, Xuezheng Gao, Jiajun Yin, Zhenhe Zhou, Ke-jia Wu

“…UPLC-MS mass spectrometry identified key components of ceAF, including various fatty acids and nucleosides. In vitro, ceAF improved viability in DSS-induced Caco-2 cells, reduced pro-inflammatory cytokines IL-1β and TNF-α, and increased the anti-inflammatory cytokine IL-10. …”
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Discrimination of superficial lymph nodes using ultrasonography and tissue metabolomics coupled with machine learning by Lu Li, Xinyue Wang, Hongyan Deng, Wenjuan Lu, Yasu Zhou, Xinhua Ye, Yong Li, Jie Wang

“…We observed significant increases in many amino acids, organic acids, lipids, and nucleosides in both lymphoma and metastasis groups, compared to the benign group. …”
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Changes in Flavor Substances of Sauced Beef during Processing Based on the Maillard Reaction by FENG Meiqin, ZENG Xiaoqing, SUN Jian

“…Ultra-high performance liquid chromatography-mass spectrometry (UPLC-MS) identified 103, 167, and 200 differential metabolites in the CT, F, and CF groups, respectively, and a large number of amino acids, dipeptides, nucleosides, and heterocyclic compounds were produced in the CF group; gas chromatography-mass spectrometry (GC-MS) results showed that CF and F promoted the production of volatile flavor substances in sauced beef. …”
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Synthesis and Antiviral Evaluation of 5-(4-Aryl-1,3-butadiyn-1-yl)-uridines and Their Phosphoramidate Pronucleotides by Evan Saillard, Otmane Bourzikat, Koffi Assa, Vincent Roy, Luigi A. Agrofoglio

“…The emergence of RNA viruses driven by global population growth and international trade highlights the urgent need for effective antiviral agents that can inhibit viral replication. Nucleoside analogs, which mimic natural nucleotides, have shown promise in targeting RNA-dependent RNA polymerases (RdRps). …”
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COVID-19 Infection Clinical Profile, Management, Outcome, and Antibody Response in Kidney Transplant Recipients: A Single Centre Experience by Sanjiv Jasuja, Gaurav Sagar, Anupam Bahl, Shalini Verma

“…The treatment options and used were steroids (100%), convalescent plasma (32.8%), ivermectin (58.2%), doxycycline (55.2%), remdesivir (34.3%), tocilizumab (10.4%), antibiotics (61.2%), anti-fungals (26.9%), low molecular weight heparin (45.3%), and oral anti-coagulants (26.9%). Anti-nucleosides (mycophenolate or azathioprine) were discontinued in 76.1% and calcineurin inhibitors (CNI) in 26.9%. …”
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