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  1. 441

    Diabetic Polyneuropathy in Type 2 Diabetes Mellitus: Inflammation, Oxidative Stress, and Mitochondrial Function by Luis Miguel Román-Pintos, Geannyne Villegas-Rivera, Adolfo Daniel Rodríguez-Carrizalez, Alejandra Guillermina Miranda-Díaz, Ernesto Germán Cardona-Muñoz

    Published 2016-01-01
    “…These free radicals cause lipid peroxidation, protein modification, and nucleic acid damage, to finally induce axonal degeneration and segmental demyelination. …”
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  2. 442

    Portable solutions for plant pathogen diagnostics: development, usage, and future potential by Anurag Yadav, Kusum Yadav

    Published 2025-01-01
    “…We examine the core technologies underlying these devices, such as biosensors, nucleic acid amplification techniques, and immunoassays, highlighting their applicability to detect bacterial, viral, and fungal pathogens in diverse agricultural settings. …”
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  3. 443

    Effects of Maillard reaction and its product AGEs on aging and age-related diseases by Huan Peng, Yuqi Gao, Chenye Zeng, Rui Hua, Yannan Guo, Yida Wang, Zhao Wang

    Published 2024-05-01
    “…Despite certain advantages based on Maillard reaction products (MRPs) found in some food for health and storage application have appeared, however, the MR occurring in human physiological environment can produce advanced glycation end products (AGEs) by non-enzymatic modif ication of macromolecules such as proteins, lipids and nucleic acid, which could change the structure and functional activity of the molecules themselves. …”
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  4. 444

    Integrative analysis of transcriptome and metabolome profiling uncovers underlying mechanisms of the enhancement of the synthesis of biofilm in Sporobolomyces pararoseus NGR under... by Dandan Wang, Nan Zeng, Chunji Li, Chunwang Li, Yunjiao Wang, Bin Chen, Jiajia Long, Ning Zhang, Bingxue Li

    Published 2025-01-01
    “…Transcriptome and metabolome profiling indicated that carbohydrate metabolism, amino acid metabolism, lipid metabolism, and nucleic acid metabolism in S. pararoseus NGR cells were significantly enriched in biofilm cells under pH 4.7 culture conditions, including 56 differentially expressed genes and 341 differential metabolites. …”
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  5. 445

    MicroRNA-3145 as a potential therapeutic target for hepatitis B virus: inhibition of viral replication via downregulation of HBS and HBX by Amrizal Muchtar, Amrizal Muchtar, Daichi Onomura, Daichi Onomura, Dan Ding, Dan Ding, Hironori Nishitsuji, Kunitada Shimotohno, Shunpei Okada, Keiji Ueda, Koichi Watashi, Takaji Wakita, Kei Iida, Kei Iida, Hironori Yoshiyama, Hisashi Iizasa

    Published 2025-01-01
    “…Current treatments for hepatitis B virus (HBV), such as interferons and nucleic acid analogs, have limitations due to side effects like depression and the development of drug-resistant mutants, highlighting the need for new therapeutic approaches. …”
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  6. 446

    The Amsterdam Declaration on Fungal Nomenclature by D.L. Hawksworth, P.W. Crous, S.A. Redhead, D.R. Reynolds, R.A. Samson, K.A. Seifert, J.W. Taylor, M.J. Wingfield

    Published 2011-06-01
    “…In addition, but not forming part of the Declaration, are reports of discussions held during the symposium on the governance of the nomenclature offungi, and the naming of fungi known only from an environmental nucleic acid sequence in particular. Possible amendments to the Draft BioCode (2011) to allow for the needs of mycologists are suggested for further consideration, and a possible example of how a fungus only known from the environment might be described is presented.…”
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  7. 447

    Antibacterial Effect of Dihydromyricetin on Specific Spoilage Organisms of Hybrid Grouper by Wenbo Huang, Jing Xie

    Published 2021-01-01
    “…The results showed that, with the increase of DMY concentration in the treatment group, the leakage of nucleic acid and protein increased significantly, the activity of ATPase and three critical enzymes in the Embden-Meyerhof-Parnas (EMP) pathway decreased significantly, and the activity of AKPase did not decrease significantly, . …”
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  8. 448

    Efficacy of spectroscopy in oral cancer detection: systematic review by Pinky Pavithran, Gheena Sukumaran

    Published 2024-09-01
    “…Specifically, when examining cytoplasm, healthy donors displayed pronounced protein (636, 845, 997, 1237, 1361, 1597, and 1645 cm–1), while patient samples presented prominent nucleic acid- (721, 780, and 1180 cm–1) and lipid- (1060, 1135, 1300, 1417, and 1745 cm–1) derived bands. …”
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  9. 449

    Prevalence and causes of rifampicin-resistance genotypic/phenotypic discrepancy detected on Xpert MTB/RIF in Singapore by Caroline Victoria Choong, Lovel Galamay, Jerlyn Huixian Woo, Angeline Jie-Yin Tey, Cynthia Bin Eng Chee

    Published 2024-12-01
    “… The Xpert Mycobacterium tuberculosis/rifampicin (MTB/RIF) (Cepheid, Sunnyvale, CA, US) has been pivotal in tuberculosis (TB) diagnostics, enabling the rapid detection of both TB and RIF resistance. Xpert, a nucleic acid amplification test (NAAT), is recommended by both the World Health Organization (WHO)1 and Singapore’s clinical management guidelines2 as a frontline diagnostic tool for TB and RIF resistance. …”
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  10. 450

    Aktivitas Daya Hambat Isolat Actinomycetes dengan Lama Fermentasi yang Berbeda terhadap Pertumbuhan Klebsiella pneumoniae by Annisa Nur Insani, Meiskha Bahar, Nunuk Nugrohowati, Retno Yulianti

    Published 2022-12-01
    “…Actinomycetes' inhibitory mechanism ranges from inhibition of cell wall synthesis to nucleic acid and protein synthesis. One Way ANOVA test showed significant differences between the inhibition zone produced by each fermentation group. …”
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  11. 451

    Tree polynomials identify a link between co-transcriptional R-loops and nascent RNA folding. by Pengyu Liu, Jacob Lusk, Nataša Jonoska, Mariel Vázquez

    Published 2024-12-01
    “…R-loops are a class of non-canonical nucleic acid structures that typically form during transcription when the nascent RNA hybridizes the DNA template strand, leaving the non-template DNA strand unpaired. …”
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  12. 452

    Differential gene expression analysis of papillary thyroid carcinoma reveals important genes for lymph node metastasis by Wan Fahmi Wan Mohamad Nazarie, Azliana Mohamad Yusof, Francis Yew Fu Tieng, Nur Fadhlina Mohamad Pakarulrazy, Rohaizak Muhammad, Shahrun Niza Abdullah Suhaimi, Nani Harlina Md Latar, Sazuita Saidin, Isa Mohamed Rose, Learn-Han Lee, Nurul-Syakima Ab Mutalib

    Published 2022-07-01
    “…The biological processes of genes expressed at higher levels in PTC LNM compared to PTC LNN were involved in cell communication, energy pathway, and metabolism, whereas ion transport, energy pathways, and regulation of nucleobase, nucleoside, nucleotide, and nucleic acid metabolisms, were downregulated. Conclusion: These findings provide further evidence for the role of cellular transport regulatory processes in metastatic disease. …”
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  13. 453

    DNA MITOKONDRIA (mtDNA) SEBAGAI SALAH SATU PEMERIKSAAN ALTERNATIF UNTUK IDENTIFIKASI BAYI PADA KASUS INFANTISIDA by Taufik Hidayat

    Published 2017-07-01
    “…Penggunaan DNA (Deoxyribose Nucleic Acid) mitokondria atau mtDNA sebagai salah satu cara untuk mengetahui hubungan antara barang  bukti  medis  dengan  pelaku  berkembang  pesat  setelah  era  90an.  …”
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  14. 454

    Integrated and streamlined microfluidic device for molecular diagnosis of pathogen through direct PCR amplification by Dohwan Lee, Tae Seok Seo

    Published 2025-01-01
    “…However, the complexity of the PCR process (including nucleic acid extraction/purification, amplification, and amplicon detection) hinders its widespread adoption in point-of-care testing, where simplicity and rapidity are essential for practical use. …”
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  15. 455

    Research on the Cross-Regional Traveling Welcome Short Messaging Service During the COVID-19 Pandemic: A Survey from Mobile Users’ Perspective by Zhiyuan Yu, Chi Zhang

    Published 2025-01-01
    “…Reminders about traveling registration and nucleic acid testing were assigned the highest importance, as they offer convenience in communicating the most up-to-date prevention and control information to mobile users during intercity travel. …”
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  16. 456

    A Small Surge in Incidence of SARS-CoV-2 Omicron Variant in the “Dynamic Zero” Period by Xiaona Li, Ruili Li, Qiguo Lian, Yang Wang, Wenkui Gu, Qinghe Meng

    Published 2023-01-01
    “…The low reproduction number and the Omicron outbreak being suppressed within a short time marked the effectiveness of the implemented public health measures, such as nucleic acid screening, social distancing, masking, vaccination, medical treatment of patients, and isolation of close contacts. …”
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  17. 457

    Bacterial Diversity Associated with Terrestrial and Aquatic Snails by Konstantinos Apostolou, Canella Radea, Alexandra Meziti, Konstantinos Ar. Kormas

    Published 2024-12-01
    “…The steadfast technological progress in nucleic acid-based approaches would cause one to expect that scientific works on the microbial symbionts of animals would be balanced at least for the farmed animals of human interest. …”
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  18. 458

    Tuberculous Otitis Media: A Mysterious Ailment by Saravana Selvan Velmurugan, Vivek Mariappan, Mohamed Siddique Samsudeen, Suresh Kumar Narayanan, Rhea Mathai, Tany James Maria

    Published 2024-05-01
    “…The granulation tissue from all the patients sent for Histopathology examination (HPE) and Cartridge Based Nucleic Acid Amplification Test (CBNAAT) examination. …”
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  19. 459

    In Silico Design of a Trans-Amplifying RNA-Based Vaccine against SARS-CoV-2 Structural Proteins by Fatemeh Nafian, Ghazal Soleymani, Zahra Pourmanouchehri, Mahnaz Kiyanjam, Simin Nafian, Sayed Mohammad Mohammadi, Hanie Jeyroudi, Sharareh Berenji Jalaei, Fatemeh Sabzpoushan

    Published 2024-01-01
    “…Nucleic acid-based vaccines allow scalable, rapid, and cell-free vaccine production in response to an emerging disease such as the current COVID-19 pandemic. …”
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  20. 460

    Role of Chest Computed Tomography versus Real Time Reverse Transcription Polymerase Chain Reaction for Diagnosis of COVID-19: A Systematic Review and Meta-Analysis by Dina M. Ali, Lamiaa G. Zake, Nevine K. El Kady

    Published 2021-01-01
    “…The diagnosis of COVID-19 depends on detection of the viral nucleic acid by real time reverse transcription polymerase chain reaction (RT-PCR). …”
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