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441
Diabetic Polyneuropathy in Type 2 Diabetes Mellitus: Inflammation, Oxidative Stress, and Mitochondrial Function
Published 2016-01-01“…These free radicals cause lipid peroxidation, protein modification, and nucleic acid damage, to finally induce axonal degeneration and segmental demyelination. …”
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442
Portable solutions for plant pathogen diagnostics: development, usage, and future potential
Published 2025-01-01“…We examine the core technologies underlying these devices, such as biosensors, nucleic acid amplification techniques, and immunoassays, highlighting their applicability to detect bacterial, viral, and fungal pathogens in diverse agricultural settings. …”
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443
Effects of Maillard reaction and its product AGEs on aging and age-related diseases
Published 2024-05-01“…Despite certain advantages based on Maillard reaction products (MRPs) found in some food for health and storage application have appeared, however, the MR occurring in human physiological environment can produce advanced glycation end products (AGEs) by non-enzymatic modif ication of macromolecules such as proteins, lipids and nucleic acid, which could change the structure and functional activity of the molecules themselves. …”
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444
Integrative analysis of transcriptome and metabolome profiling uncovers underlying mechanisms of the enhancement of the synthesis of biofilm in Sporobolomyces pararoseus NGR under...
Published 2025-01-01“…Transcriptome and metabolome profiling indicated that carbohydrate metabolism, amino acid metabolism, lipid metabolism, and nucleic acid metabolism in S. pararoseus NGR cells were significantly enriched in biofilm cells under pH 4.7 culture conditions, including 56 differentially expressed genes and 341 differential metabolites. …”
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445
MicroRNA-3145 as a potential therapeutic target for hepatitis B virus: inhibition of viral replication via downregulation of HBS and HBX
Published 2025-01-01“…Current treatments for hepatitis B virus (HBV), such as interferons and nucleic acid analogs, have limitations due to side effects like depression and the development of drug-resistant mutants, highlighting the need for new therapeutic approaches. …”
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446
The Amsterdam Declaration on Fungal Nomenclature
Published 2011-06-01“…In addition, but not forming part of the Declaration, are reports of discussions held during the symposium on the governance of the nomenclature offungi, and the naming of fungi known only from an environmental nucleic acid sequence in particular. Possible amendments to the Draft BioCode (2011) to allow for the needs of mycologists are suggested for further consideration, and a possible example of how a fungus only known from the environment might be described is presented.…”
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447
Antibacterial Effect of Dihydromyricetin on Specific Spoilage Organisms of Hybrid Grouper
Published 2021-01-01“…The results showed that, with the increase of DMY concentration in the treatment group, the leakage of nucleic acid and protein increased significantly, the activity of ATPase and three critical enzymes in the Embden-Meyerhof-Parnas (EMP) pathway decreased significantly, and the activity of AKPase did not decrease significantly, . …”
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448
Efficacy of spectroscopy in oral cancer detection: systematic review
Published 2024-09-01“…Specifically, when examining cytoplasm, healthy donors displayed pronounced protein (636, 845, 997, 1237, 1361, 1597, and 1645 cm–1), while patient samples presented prominent nucleic acid- (721, 780, and 1180 cm–1) and lipid- (1060, 1135, 1300, 1417, and 1745 cm–1) derived bands. …”
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449
Prevalence and causes of rifampicin-resistance genotypic/phenotypic discrepancy detected on Xpert MTB/RIF in Singapore
Published 2024-12-01“… The Xpert Mycobacterium tuberculosis/rifampicin (MTB/RIF) (Cepheid, Sunnyvale, CA, US) has been pivotal in tuberculosis (TB) diagnostics, enabling the rapid detection of both TB and RIF resistance. Xpert, a nucleic acid amplification test (NAAT), is recommended by both the World Health Organization (WHO)1 and Singapore’s clinical management guidelines2 as a frontline diagnostic tool for TB and RIF resistance. …”
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450
Aktivitas Daya Hambat Isolat Actinomycetes dengan Lama Fermentasi yang Berbeda terhadap Pertumbuhan Klebsiella pneumoniae
Published 2022-12-01“…Actinomycetes' inhibitory mechanism ranges from inhibition of cell wall synthesis to nucleic acid and protein synthesis. One Way ANOVA test showed significant differences between the inhibition zone produced by each fermentation group. …”
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451
Tree polynomials identify a link between co-transcriptional R-loops and nascent RNA folding.
Published 2024-12-01“…R-loops are a class of non-canonical nucleic acid structures that typically form during transcription when the nascent RNA hybridizes the DNA template strand, leaving the non-template DNA strand unpaired. …”
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452
Differential gene expression analysis of papillary thyroid carcinoma reveals important genes for lymph node metastasis
Published 2022-07-01“…The biological processes of genes expressed at higher levels in PTC LNM compared to PTC LNN were involved in cell communication, energy pathway, and metabolism, whereas ion transport, energy pathways, and regulation of nucleobase, nucleoside, nucleotide, and nucleic acid metabolisms, were downregulated. Conclusion: These findings provide further evidence for the role of cellular transport regulatory processes in metastatic disease. …”
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453
DNA MITOKONDRIA (mtDNA) SEBAGAI SALAH SATU PEMERIKSAAN ALTERNATIF UNTUK IDENTIFIKASI BAYI PADA KASUS INFANTISIDA
Published 2017-07-01“…Penggunaan DNA (Deoxyribose Nucleic Acid) mitokondria atau mtDNA sebagai salah satu cara untuk mengetahui hubungan antara barang bukti medis dengan pelaku berkembang pesat setelah era 90an. …”
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454
Integrated and streamlined microfluidic device for molecular diagnosis of pathogen through direct PCR amplification
Published 2025-01-01“…However, the complexity of the PCR process (including nucleic acid extraction/purification, amplification, and amplicon detection) hinders its widespread adoption in point-of-care testing, where simplicity and rapidity are essential for practical use. …”
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455
Research on the Cross-Regional Traveling Welcome Short Messaging Service During the COVID-19 Pandemic: A Survey from Mobile Users’ Perspective
Published 2025-01-01“…Reminders about traveling registration and nucleic acid testing were assigned the highest importance, as they offer convenience in communicating the most up-to-date prevention and control information to mobile users during intercity travel. …”
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456
A Small Surge in Incidence of SARS-CoV-2 Omicron Variant in the “Dynamic Zero” Period
Published 2023-01-01“…The low reproduction number and the Omicron outbreak being suppressed within a short time marked the effectiveness of the implemented public health measures, such as nucleic acid screening, social distancing, masking, vaccination, medical treatment of patients, and isolation of close contacts. …”
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457
Bacterial Diversity Associated with Terrestrial and Aquatic Snails
Published 2024-12-01“…The steadfast technological progress in nucleic acid-based approaches would cause one to expect that scientific works on the microbial symbionts of animals would be balanced at least for the farmed animals of human interest. …”
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458
Tuberculous Otitis Media: A Mysterious Ailment
Published 2024-05-01“…The granulation tissue from all the patients sent for Histopathology examination (HPE) and Cartridge Based Nucleic Acid Amplification Test (CBNAAT) examination. …”
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459
In Silico Design of a Trans-Amplifying RNA-Based Vaccine against SARS-CoV-2 Structural Proteins
Published 2024-01-01“…Nucleic acid-based vaccines allow scalable, rapid, and cell-free vaccine production in response to an emerging disease such as the current COVID-19 pandemic. …”
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460
Role of Chest Computed Tomography versus Real Time Reverse Transcription Polymerase Chain Reaction for Diagnosis of COVID-19: A Systematic Review and Meta-Analysis
Published 2021-01-01“…The diagnosis of COVID-19 depends on detection of the viral nucleic acid by real time reverse transcription polymerase chain reaction (RT-PCR). …”
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