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241
Effects of B9 and B12 vitamins deficiency on the genesis of megaloblastic anemia
Published 2023-11-01“…Vitamins B9 and B12 participate in the normal synthesis of nucleic acids, being directly involved in the synthesis of purines and pyrimidines, as well as cell maturation. …”
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242
The Effect of Edible Mushroom on Health and Their Biochemistry
Published 2022-01-01“…They contain varying amounts of carbohydrates, proteins, nucleic acids, lipids, minerals, terpenoids, phenolic compounds, steroids, and lectins and vitamins, as well as lowering cholesterol levels in the body. …”
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243
The Redox System in C. elegans, a Phylogenetic Approach
Published 2012-01-01“…ROS cause oxidative damage to cellular components such as proteins, lipids, and nucleic acids. While the role of ROS in cellular damage is frequently all that is noted, ROS are also important in redox signalling. …”
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244
Research progress on the role of extracellular vesicles in the pathogenesis of diabetic kidney disease
Published 2024-12-01“…Extracellular vesicles (EVs) contain cell-derived membrane proteins, nucleic acids (such as DNA and RNA) and other important cellular components and are involved in intercellular information and substance transmission. …”
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245
DETERMINATION OF INFECTIOUS DISEASESBY POLYMERASE CHAIN REACTION
Published 2024-09-01“…This research studies will identify active infections such as arboviruses, sexually transmitted diseases and bacterial infections through the identification of infectious agents and nucleic acids via PCRs methods. There must be stronger molecular science to enhance infectious agent detection capabilities to track the spread of infectious diseases and take appropriate measures to support patients and the health workers themselves. …”
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246
Development of a droplet digital PCR method for the detection of Ureaplasma urealyticum
Published 2025-01-01“…Methods: Primers were designed for the ParC gene of UU. Nucleic acids from a standard strain of UU were extracted. …”
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247
Suitability of Commercial Transport Media for Biological Pathogens under Nonideal Conditions
Published 2011-01-01“…The results demonstrate that COTS media, although sufficient for the preservation of nucleic acid and proteinaceous material, are not capable of maintaining an accurate representation of biothreat agents at the time of collection.…”
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248
The unexpected role of the STING protein in lipid metabolism
Published 2023-04-01“…Detection of cytosolic pathological nucleic acids is a key step for the initiation of innate immune responses. …”
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249
Recent advances in polymeric nanoparticles for the treatment of hepatic diseases
Published 2025-01-01“…Furthermore, this paper reviewed the application of polymeric nanoparticles -mainly chitosan (CS), hyaluronic acid (HA), polyethylene glycol (PEG) and poly (lactic-co-glycolic acid) (PLGA)-in liver disease treatment, focusing on their use in various delivery systems for pure bioactive compounds of natural origin, drugs, nucleic acids, peptides, and others. Finally, the challenges and future perspectives of the NPs were discussed to provide guidance for further research directions, with the aim of promoting the clinical application of nanotherapeutics in treating hepatic diseases.…”
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250
Tumor-Related Exosomes Contribute to Tumor-Promoting Microenvironment: An Immunological Perspective
Published 2017-01-01“…Exosomes are a kind of cell-released membrane-form structures which contain proteins, lipids, and nucleic acids. These vesicular organelles play a key role in intercellular communication. …”
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251
NPM1/B23: A Multifunctional Chaperone in Ribosome Biogenesis and Chromatin Remodeling
Published 2011-01-01“…At a first glance, ribosome biogenesis and chromatin remodeling are quite different processes, but they share a common problem involving interactions between charged nucleic acids and small basic proteins that may result in unwanted intracellular aggregations. …”
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252
Extracellular vesicles—a new player in the development of urinary bladder cancer
Published 2025-01-01“…EVs can transport proteins, lipids, or nucleic acids to specific target cells. What brings more attention and potential implications is the fact that cancer cells secrete more EVs than non-malignant cells. …”
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253
Menopause mysteries: the exosome-inflammation connection
Published 2025-01-01“…Abstract Extracellular vesicles, or exosomes, are produced by every type of cell and contain metabolites, proteins, lipids, and nucleic acids. Their role in health and disease is to influence different aspects of cell biology and to act as intermediaries between cells. …”
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254
Exosome in Crosstalk between Inflammation and Angiogenesis: A Potential Therapeutic Strategy for Stroke
Published 2022-01-01“…Exosomes are the heterogeneous population of extracellular vesicles which play critical roles in intercellular communication through transmitting various proteins and nucleic acids to nearby and distant recipient cells by body fluids and circulation. …”
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255
Consequences of Hyperoxia and the Toxicity of Oxygen in the Lung
Published 2011-01-01“…Pathophysiological processes are associated with increased levels of hyperoxia-induced reactive O2 species (ROS) which may readily react with surrounding biological tissues, damaging lipids, proteins, and nucleic acids. Protective antioxidant defenses can become overwhelmed with ROS leading to oxidative stress. …”
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256
Virosome, a hybrid vehicle for efficient and safe drug delivery and its emerging application in cancer treatment
Published 2015-06-01“…Studies have shown that a virosome can carry various biologically active molecules, such as nucleic acids, peptides, proteins and small organic molecules. …”
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257
Viruses Seen by Our Cells: The Role of Viral RNA Sensors
Published 2018-01-01“…These receptors have the capacity to sense the presence of viral nucleic acids as pathogen-associated molecular patterns (PAMPs). …”
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258
Stability Constants of Mixed Ligand Complexes of Nickel(II) with Adenine and Some Amino Acids
Published 2015-01-01“…Nickel is also present in nucleic acids, though its function in DNA or RNA is still not clearly understood. …”
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259
The Role of TLR2, TLR4, and TLR9 in the Pathogenesis of Atherosclerosis
Published 2016-01-01“…TLR9 is activated by CpG motifs in nucleic acids and have been implicated in macrophage activation and the uptake of oxLDL from the circulation. …”
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260
Potential for Isolation of Immortalized Hepatocyte Cell Lines by Liver-Directed In Vivo Gene Delivery of Transposons in Mice
Published 2019-01-01“…Here, we proposed that a combination of transposon- and liver-directed introduction of nucleic acids may confer acquisition of unlimited cellular proliferative potential on hepatocytes, enabling the possible isolation of immortalized hepatocyte cell lines, which has often failed using more traditional immortalization methods.…”
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