Suggested Topics within your search.
Showing 221 - 240 results of 537 for search '"nucleic acids"', query time: 0.05s Refine Results
  1. 221
    Personalized allele-specific antisense oligonucleotides for GNAO1-neurodevelopmental disorder

    Personalized allele-specific antisense oligonucleotides for GNAO1-neurodevelopmental disorder by Inna Shomer, Nofar Mor, Shaul Raviv, Noga Budick-Harmelin, Tanya Matchevich, Sharon Avkin-Nachum, Yoach Rais, Rebecca Haffner-Krausz, Ariela Haimovich, Aviv Ziv, Reut Fluss, Bruria Ben-Ze’ev, Gali Heimer, Denis N. Silachev, Vladimir L. Katanaev, Dan Dominissini

    Published 2025-03-01
    “…Molecular Therapy: Nucleic Acids…”
    Get full text
    Article
    Save to List
    Saved in:
  2. 222
    miR-125b differentially impacts mineralization in dexamethasone and calcium-treated human mesenchymal stem cells

    miR-125b differentially impacts mineralization in dexamethasone and calcium-treated human mesenchymal stem cells by Virginie Joris, Elizabeth R. Balmayor, Martijn van Griensven

    Published 2025-03-01
    “…Molecular Therapy: Nucleic Acids…”
    Get full text
    Article
    Save to List
    Saved in:
  3. 223
    Antisense oligonucleotide-mediated exon 27 skipping restores dysferlin function in dysferlinopathy patient-derived muscle cells

    Antisense oligonucleotide-mediated exon 27 skipping restores dysferlin function in dysferlinopathy patient-derived muscle cells by Naoki Suzuki

    Published 2025-03-01
    “…Molecular Therapy: Nucleic Acids…”
    Get full text
    Article
    Save to List
    Saved in:
  4. 224
    Unleashing the TLR9-driven multilineage differentiation of myeloid leukemia cells in vivo

    Unleashing the TLR9-driven multilineage differentiation of myeloid leukemia cells in vivo by Katarzyna Piwocka

    Published 2025-03-01
    “…Molecular Therapy: Nucleic Acids…”
    Get full text
    Article
    Save to List
    Saved in:
  5. 225
    CleanCap M6 inhibits decapping of exogenously delivered IVT mRNA

    CleanCap M6 inhibits decapping of exogenously delivered IVT mRNA by Zachary F. Mandell, Andrew Ujita, Jordana Henderson, Anthony Truong, Coleen Vo, Farinaz Rezvani, Nona Abolhassani, Alexandre Lebedev, Chunping Xu, Inna Koukhareva, Stephanie Ramos, Kate Broderick, Benjamin Hudson, Jeff Coller

    Published 2025-03-01
    “…Molecular Therapy: Nucleic Acids…”
    Get full text
    Article
    Save to List
    Saved in:
  6. 226
    High-accuracy crRNA array assembly strategy for multiplex CRISPR

    High-accuracy crRNA array assembly strategy for multiplex CRISPR by Xiangtong Zhao, Lixian Yang, Peng Li, Zijing Cheng, Yongshi Jia, Limin Luo, Aihong Bi, Hanchu Xiong, Haibo Zhang, Hongen Xu, Jinrui Zhang, Yaodong Zhang

    Published 2025-03-01
    “…Molecular Therapy: Nucleic Acids…”
    Get full text
    Article
    Save to List
    Saved in:
  7. 227
    In vitro high-content screening reveals miR-429 as a protective molecule in photoreceptor degeneration

    In vitro high-content screening reveals miR-429 as a protective molecule in photoreceptor degeneration by Georgios Petrogiannakis, Irene Guadagnino, Santiago Negueruela, Martina Di Guida, Elena Marrocco, Mariateresa Pizzo, Annalaura Torella, Mariateresa Zanobio, Marianthi Karali, Diego Luis Medina, Sabrina Carrella, Sandro Banfi

    Published 2025-03-01
    “…Molecular Therapy: Nucleic Acids…”
    Get full text
    Article
    Save to List
    Saved in:
  8. 228
    Extracellular viral microRNAs as biomarkers of virus infection in human cells

    Extracellular viral microRNAs as biomarkers of virus infection in human cells by Cheryl Chan, Joanne Xin Yi Loh, Wei-Xiang Sin, Denise Bei Lin Teo, Nicholas Kwan Zen Tan, Chandramouli Nagarajan, Yunxin Chen, Francesca Lorraine Wei Inng Lim, Michael E. Birnbaum, Rohan B.H. Williams, Stacy L. Springs

    Published 2025-03-01
    “…Molecular Therapy: Nucleic Acids…”
    Get full text
    Article
    Save to List
    Saved in:
  9. 229
    siRNA tackles cancer: Immune checkpoint inhibitors and siRNA combinations

    siRNA tackles cancer: Immune checkpoint inhibitors and siRNA combinations by Andrew H. Coles

    Published 2025-03-01
    “…Molecular Therapy: Nucleic Acids…”
    Get full text
    Article
    Save to List
    Saved in:
  10. 230
    Selective suppression of influenza A/H5N1 virus replication <i>in vitro</i> using nanocomplexes consisting of siRNA and aminopropylsilanol nanoparticles

    Selective suppression of influenza A/H5N1 virus replication <i>in vitro</i> using nanocomplexes consisting of siRNA and aminopropylsilanol nanoparticles by Marina N. Repkova, Asya S. Levina, Oleg Yu. Mazurkov, Elena V. Makarevich, Ekaterina I. Filippova, Natalya A. Mazurkova, Valentina F. Zarytova

    Published 2024-12-01
    “…The development of effective preparations capable of acting on target nucleic acids in cells is an urgent task. The aim of the study is to create nanocomplexes consisting of aminopropylsilanol nanoparticles and short interfering RNA (siRNA) to study their effect on target nucleic acids by the example of inhibition of influenza A virus replication in vitro. …”
    Get full text
    Article
    Save to List
    Saved in:
  11. 231
    Radical Reactions in the Gas Phase: Recent Development and Application in Biomolecules

    Radical Reactions in the Gas Phase: Recent Development and Application in Biomolecules by Yang Gao, Jiexun Bu, Zhou Peng, Biwei Yang

    Published 2014-01-01
    “…Due to the extensively studied peptide fragmentation, this review focuses only on nonpeptide biomolecules such as nucleic acids, carbohydrates, and phospholipids.…”
    Get full text
    Article
    Save to List
    Saved in:
  12. 232
    Advances in RNA-Based Therapeutics: Challenges and Innovations in RNA Delivery Systems

    Advances in RNA-Based Therapeutics: Challenges and Innovations in RNA Delivery Systems by Yuxuan Liu, Yaohui Ou, Linlin Hou

    Published 2024-12-01
    “…Nucleic acids, as carriers of genetic information, have found wide applications in both medical and research fields, including gene editing, disease diagnostics, and drug development. …”
    Get full text
    Article
    Save to List
    Saved in:
  13. 233
    Oligonucleotides as a Novel Therapeutic Approach: An Innovative Area for Drug Delivery in Neurological Disorders

    Oligonucleotides as a Novel Therapeutic Approach: An Innovative Area for Drug Delivery in Neurological Disorders by Yasir Qasim Almajidi, Rana Kadum Muslim, Yaseen T. khalf

    Published 2025-01-01
    “…However, the delivery of nucleic acids to the central nervous system (CNS) by the systemic route, remains a major hurdle. …”
    Get full text
    Article
    Save to List
    Saved in:
  14. 234
    Phosphoryl guanidine oligonucleotides as primers for RNA-dependent DNA synthesis using murine leukemia virus reverse transcriptase

    Phosphoryl guanidine oligonucleotides as primers for RNA-dependent DNA synthesis using murine leukemia virus reverse transcriptase by E. S. Dyudeeva, I. A. Pyshnaya

    Published 2022-03-01
    “…The best-known completely uncharged analogs of oligonucleotides – morpholine oligonucleotides and peptide nucleic acids – cannot be substrates for enzymes that process nucleic acids. …”
    Get full text
    Article
    Save to List
    Saved in:
  15. 235
    CRISPR/Cas Enzyme Catalysis in Liquid–Liquid Phase‐Separated Systems

    CRISPR/Cas Enzyme Catalysis in Liquid–Liquid Phase‐Separated Systems by Yaqin Zhang, Jianai Chen, Zhina Wu, Chenfei Zhao, Rui Wang, Zhiping Li, Jiasi Wang, Di Wang

    Published 2025-01-01
    “…The findings revealed that nucleic acids and proteins tended to be distributed in the dextran‐rich phase. …”
    Get full text
    Article
    Save to List
    Saved in:
  16. 236
    Evaluation of a Commercial Multiplex Real-Time PCR with Melting Curve Analysis for the Detection of <i>Mycobacterium tuberculosis</i> Complex and Five Nontuberculous Mycobacterial Species

    Evaluation of a Commercial Multiplex Real-Time PCR with Melting Curve Analysis for the Detection of <i>Mycobacterium tuberculosis</i> Complex and Five Nontuberculous Mycobacterial... by Keun Ju Kim, Yunhee Chang, Seung Gyu Yun, Myung-Hyun Nam, Yunjung Cho

    Published 2024-12-01
    “…Results: The NeoPlex assay successfully detected nucleic acids in 87 of the 91 isolates (95.6%). Notably, it identified additional mycobacterial nucleic acids not detected by the LPA in eight isolates. …”
    Get full text
    Article
    Save to List
    Saved in:
  17. 237
    Human Breast Carcinomal Tissues Display Distinctive FTIR Spectra: Implication for the Histological Characterization of Carcinomas

    Human Breast Carcinomal Tissues Display Distinctive FTIR Spectra: Implication for the Histological Characterization of Carcinomas by Tiyu Gao, Jun Feng, Yunxiang Ci

    Published 1999-01-01
    “…Some distinctive spectral differences which are mainly due to nucleic acids and proteins are observed between normal and carcinomal tissues. …”
    Get full text
    Article
    Save to List
    Saved in:
  18. 238
    DNA-loaded targeted nanoparticles as a safe platform to produce exogenous proteins in tumor B cells

    DNA-loaded targeted nanoparticles as a safe platform to produce exogenous proteins in tumor B cells by Maria Cristina Grimaldi, Sara Bozzer, Dick J. Sjöström, Dick J. Sjöström, Linnea I. Andersson, Tom Eirik Mollnes, Tom Eirik Mollnes, Per H. Nilsson, Per H. Nilsson, Luca De Maso, Federico Riccardi, Michele Dal Bo, Daniele Sblattero, Paolo Macor

    Published 2025-01-01
    “…IntroductionThe functionalization of nanoparticles (NPs) with an antiCD19 targeting mechanism represents a promising approach for the selective delivery of drugs and nucleic acids into normal and tumor B cells. This strategy has the advantage of minimizing off-target effects by restricting gene delivery to the desired cell population. …”
    Get full text
    Article
    Save to List
    Saved in:
  19. 239
    Biochemistry : the molecular basis of life /

    Biochemistry : the molecular basis of life / by McKee, Trudy

    Published 2017
    Table of Contents: “…Machine generated contents note: -- Table of Contents -- Chapter 1 Biochemistry: An Introduction -- Chapter 2 Living Cells -- Chapter 3 Water: The Matrix of Life -- Chapter 4 Energy -- Chapter 5 Amino Acids, Peptides, and Proteins -- Chapter 6 Enzymes -- Chapter 7 Carbohydrates -- Chapter 8 Carbohydrate Metabolism -- Chapter 9 Aerobic Metabolism I: The Citric Acid Cycle -- Chapter 10 Aerobic Metabolism II: Electron Transport and Oxidative Phosporylation -- Chapter 11 Lipids and Membranes -- Chapter 12 Lipid Metabolism -- Chapter 13 Photosynthesis -- Chapter 14 Nitrogen Metabolism I: Synthesis -- Chapter 15 Nitrogen Metabolism I: Degradation -- Chapter 16 Integration of Metabolism -- Chapter 17 Nucleic Acids -- Chapter 18 Genetic Information -- Chapter 19 Protein Synthesis.…”
    View in OPAC
    Book
    Save to List
    Saved in:
  20. 240
    Biochemistry : the molecular basis of life /

    Biochemistry : the molecular basis of life / by McKee, Trudy, McKee, James R. (James Robert), 1946-

    Published 2017
    Table of Contents: “…Machine generated contents note: -- Table of Contents -- Chapter 1 Biochemistry: An Introduction -- Chapter 2 Living Cells -- Chapter 3 Water: The Matrix of Life -- Chapter 4 Energy -- Chapter 5 Amino Acids, Peptides, and Proteins -- Chapter 6 Enzymes -- Chapter 7 Carbohydrates -- Chapter 8 Carbohydrate Metabolism -- Chapter 9 Aerobic Metabolism I: The Citric Acid Cycle -- Chapter 10 Aerobic Metabolism II: Electron Transport and Oxidative Phosporylation -- Chapter 11 Lipids and Membranes -- Chapter 12 Lipid Metabolism -- Chapter 13 Photosynthesis -- Chapter 14 Nitrogen Metabolism I: Synthesis -- Chapter 15 Nitrogen Metabolism I: Degradation -- Chapter 16 Integration of Metabolism -- Chapter 17 Nucleic Acids -- Chapter 18 Genetic Information -- Chapter 19 Protein Synthesis.…”
    View in OPAC
    Book
    Save to List
    Saved in:

Search Tools: