Specific and sensitive detection of bovine coronavirus using CRISPR-Cas13a combined with RT-RAA technology by Zili Liang, Ruxing Luo, Qifu He, Cheng Tang, Zhidong Zhang, Yanmin Li, Zijing Guo

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A novel chitosan microsphere as food processing enzyme immobilization carrier and its application in nucleotide production by Xiao-Yan Yin, Rui-Fan Yang, Zhong-Hua Yang

Subjects: “…Nucleic acid hydrolysis…”
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An innovative mode of whole-process non-contact single-person sample collection of nucleic acid testing (一种全程无接触式单人核酸检测样本采集创新模式) by ZHANG Lijun (张丽君), TANG Ling (唐玲)

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Peptide nucleic acid (PNA) clamps reduce amplification of host chloroplast and mitochondria rRNA gene sequences and increase detected diversity in 16S rRNA gene profiling analysis of oak-associated microbiota by Usman Hussain, Jim Downie, Amy Ellison, Sandra Denman, James McDonald, Marine C. Cambon

“…Abstract Background Acquiring representative bacterial 16S rRNA gene community profiles in plant microbiome studies can be challenging due to the excessive co-amplification of host chloroplast and mitochondrial rRNA gene sequences that reduce counts of plant-associated bacterial sequences. Peptide Nucleic Acid (PNA) clamps prevent this by blocking PCR primer binding or binding within the amplified region of non-target DNA to stop the function of DNA polymerase. …”
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Molecular Programming Design of Glyconucleic Acid Aptamer with High Stability by Yongqi Han, Rongjun Zhang, Hong‐Liang Bao, Mei Yang, Yuan Gao, Xiaobo Gao, Ruowen Wang, Weihong Tan, Ding‐Kun Ji

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Grand challenge in biosafety and biosecurity by Stephen A. Morse

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Performance evaluation of the high-throughput quantitative Alinity m Epstein-Barr virus assay by D. Yitzchak Goldstein, Mark M. Sasaki, Momka Narlieva, Nhi Nhan, Tianxi Liu, April Kegl, Tanjina Akter, Tanisha Dickerson, Eriel Thornton, Patricia Jim, Stephen Young, Danijela Lucic, Julie W. Hirschhorn

Subjects: “…nucleic acid amplification…”
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A Sensitive, Specific and Fast Electrochemical‐based Nanobiosensor Diagnostic for Xanthomonas albilineans, the Cause of Sugarcane Leaf Scald Disease by Moutoshi Chakraborty, Shamsul Arafin Bhuiyan, Simon Strachan, Muhammad J.A. Shiddiky, Nam‐Trung Nguyen, Narshone Soda, Rebecca Ford

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Current Treatment Regimens and Promising Molecular Therapies for Chronic Hepatobiliary Diseases by Marilena Durazzo, Arianna Ferro, Victor Manuel Navarro-Tableros, Andrea Gaido, Paolo Fornengo, Fiorella Altruda, Renato Romagnoli, Søren K. Moestrup, Pier Luigi Calvo, Sharmila Fagoonee

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Implications of noncoding RNAs for cancer therapy: Are we aiming at the right targets? by Amil Shah

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Development of a cell-penetrating peptide-based nanocomplex for long-term delivery of intact mitochondrial DNA into epithelial cells by Kyrie Wilson, Charles Holjencin, Hwaran Lee, Balasubramaniam Annamalai, Masaaki Ishii, Jeremy L. Gilbert, Andrew Jakymiw, Bärbel Rohrer

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Design and application of a fully automatic throat swab cartridge exit device for nucleic acid detection (一种用于核酸检测的全自动咽拭子弹出装置的设计与应用) by ZHU Kunkun (朱坤坤), XU Yuanle (许远乐), WANG Yuena (王岳娜), WU Bo (武博)

Subjects: “…nucleic acid detection…”
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Advancing poliovirus eradication: lessons learned from piloting direct molecular detection of polioviruses in high-risk and priority geographies by Paula L. Marcet, Brandon Short, Ashley Deas, Hong Sun, Chelsea Harrington, Shahzad Shaukat, Muhammad Masroor Alam, Marycelin Baba, Adedayo Faneye, Prossy Namuwulya, Lea Necitas Apostol, Tamer Elshaarawy, John Kofi Odoom, Peter Borus, Shelina Moonsamy, Yogolelo Riziki, Marie Claire Endegue Zanga, Mesfin Tefera, Anfumbom K. W. Kfutwah, Salmaan Sharif, Varja Grabovac, Cara C. Burns, Nancy Gerloff

Subjects: “…nucleic acid extraction…”
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Difference of SARS-CoV-2 infection and influence factors between people with and without HIV infection by Jianhui Yang, Esben Strodl, Dandan Zhang, Haibo Jiang, Kun Chu, Shiwen Tan, Zehao Ye, Hongbo Shi, Feng Tong, Weiqing Chen

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Design and application of a pharyngeal swab samples collection device (一种咽拭子采集装置的设计及应用) by KANG Jie (康杰), LU Minghui (路明惠), TIAN Ruixi (田润溪), FAN Jiao (范姣), WANG Lin (王琳)

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Vector‐Free Deep Tissue Targeting of DNA/RNA Therapeutics via Single Capacitive Discharge Conductivity‐Clamped Gene Electrotransfer by Jeremy L. Pinyon, Georg vonJonquieres, Stephen L. Mow, Amr Al Abed, Keng‐Yin Lai, Mathumathi Manoharan, Edward N. Crawford, Stanley H. Xue, Sarah Smith‐Moore, Lisa J. Caproni, Sarah Milsom, Matthias Klugmann, Nigel H. Lovell, Gary D. Housley

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A Novel Approach for In Vitro Testing and Hazard Evaluation of Nanoformulated RyR2-Targeting siRNA Drugs Using Human PBMCs by Valeria Bettinsoli, Gloria Melzi, Angelica Crea, Lorenzo Degli Esposti, Michele Iafisco, Daniele Catalucci, Paolo Ciana, Emanuela Corsini

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The amount of DNA and RNA in primary cancer cells and their metastases by Oleksandr Herasymenko, Kostyantyn Gerasymenko, Olha Herasymenko

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IMPLEMENTATION OF 454 LIFE SCIENCES TECHNOLOGY LABORATORY PRACTICES by N. G. Zinyakov, Ye. V. Ovchinnikova, S. P. Lazareva, A. A. Kozlov, I. A. Chvalas

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The peculiar characteristics and advancement in diagnostic methodologies of influenza A virus by Muhammad Asif Raza, Muhammad Asif Raza, Muhammad Awais Ashraf, Muhammad Awais Ashraf, Muhammad Nabeel Amjad, Muhammad Nabeel Amjad, Ghayyas Ud Din, Ghayyas Ud Din, Bei Shen, Yihong Hu, Yihong Hu

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