Personalized allele-specific antisense oligonucleotides for GNAO1-neurodevelopmental disorder by Inna Shomer, Nofar Mor, Shaul Raviv, Noga Budick-Harmelin, Tanya Matchevich, Sharon Avkin-Nachum, Yoach Rais, Rebecca Haffner-Krausz, Ariela Haimovich, Aviv Ziv, Reut Fluss, Bruria Ben-Ze’ev, Gali Heimer, Denis N. Silachev, Vladimir L. Katanaev, Dan Dominissini

“…Molecular Therapy: Nucleic Acids…”
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miR-125b differentially impacts mineralization in dexamethasone and calcium-treated human mesenchymal stem cells by Virginie Joris, Elizabeth R. Balmayor, Martijn van Griensven

“…Molecular Therapy: Nucleic Acids…”
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Antisense oligonucleotide-mediated exon 27 skipping restores dysferlin function in dysferlinopathy patient-derived muscle cells by Naoki Suzuki

“…Molecular Therapy: Nucleic Acids…”
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Unleashing the TLR9-driven multilineage differentiation of myeloid leukemia cells in vivo by Katarzyna Piwocka

“…Molecular Therapy: Nucleic Acids…”
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CleanCap M6 inhibits decapping of exogenously delivered IVT mRNA by Zachary F. Mandell, Andrew Ujita, Jordana Henderson, Anthony Truong, Coleen Vo, Farinaz Rezvani, Nona Abolhassani, Alexandre Lebedev, Chunping Xu, Inna Koukhareva, Stephanie Ramos, Kate Broderick, Benjamin Hudson, Jeff Coller

“…Molecular Therapy: Nucleic Acids…”
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High-accuracy crRNA array assembly strategy for multiplex CRISPR by Xiangtong Zhao, Lixian Yang, Peng Li, Zijing Cheng, Yongshi Jia, Limin Luo, Aihong Bi, Hanchu Xiong, Haibo Zhang, Hongen Xu, Jinrui Zhang, Yaodong Zhang

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In vitro high-content screening reveals miR-429 as a protective molecule in photoreceptor degeneration by Georgios Petrogiannakis, Irene Guadagnino, Santiago Negueruela, Martina Di Guida, Elena Marrocco, Mariateresa Pizzo, Annalaura Torella, Mariateresa Zanobio, Marianthi Karali, Diego Luis Medina, Sabrina Carrella, Sandro Banfi

“…Molecular Therapy: Nucleic Acids…”
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Extracellular viral microRNAs as biomarkers of virus infection in human cells by Cheryl Chan, Joanne Xin Yi Loh, Wei-Xiang Sin, Denise Bei Lin Teo, Nicholas Kwan Zen Tan, Chandramouli Nagarajan, Yunxin Chen, Francesca Lorraine Wei Inng Lim, Michael E. Birnbaum, Rohan B.H. Williams, Stacy L. Springs

“…Molecular Therapy: Nucleic Acids…”
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siRNA tackles cancer: Immune checkpoint inhibitors and siRNA combinations by Andrew H. Coles

“…Molecular Therapy: Nucleic Acids…”
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The Laboratory Diagnosis of Neisseria gonorrhoeae by Lai-King Ng, Irene E Martin

“…Nucleic acid methods can also be used to detect the presence of low numbers in a specimen. …”
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Antiviral and Immunoenhancing Properties of 7-Thia-8-Oxoguanosine and Related Guanosine Analogues by Donald F Smee, Howard B Cottam, Brahma S Sharma, Ganesh D Kini, Ganapathi R Revankar, Emmanuel A Ojo-Amaize, Robert W Sidwell, Weldon B Jolley, Roland K Robins

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A drop dispenser for simplifying on-farm detection of foodborne pathogens. by Mohsen Ranjbaran, Simerdeep Kaur, Jiangshan Wang, Bibek Raut, Mohit S Verma

“…Nucleic-acid biosensors have emerged as useful tools for on-farm detection of foodborne pathogens on fresh produce. …”
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DNA replication initiation drives focal mutagenesis and rearrangements in human cancers by Pierre Murat, Guillaume Guilbaud, Julian E. Sale

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Detection of Bacterial Wilt Pathogen and Isolation of Its Bacteriophage from Banana in Lumajang Area, Indonesia by Hardian Susilo Addy, Norita Fatatik Azizi, Paniman Ashna Mihardjo

“…Moreover, two bacteriophages were obtained from this experiment (ϕRSSKD1 and ϕRSSKD2), which were able to infect all nine R. solanacearum isolates. Nucleic acid analysis showed that the nucleic acid of bacteriophages was DNA (deoxyribonucleic acid).…”
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CRISPR/Cas12a-based method coupled with isothermal amplification to identify Alternaria spp. isolated from wheat grain samples by Aisha Shaizadinova, Aisha Shaizadinova, Meruyert Amanzholova, Meruyert Amanzholova, Irina Rukavitsina, Sailau Abeldenov, Anuar Rysbekovich Zhumakayev

“…Isothermal amplification methods, including nucleic acid sequence-based amplification (NASBA), loop-mediated isothermal amplification (LAMP), and recombinase polymerase amplification (RPA), enable nucleic acid amplification at constant temperatures, making them ideal for point-of-care diagnostics without the need for thermal cycling equipment. …”
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The Gut Microbiota-Related Antihyperglycemic Effect of Metformin by Izabela Szymczak-Pajor, Józef Drzewoski, Małgorzata Kozłowska, Jan Krekora, Agnieszka Śliwińska

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The laboratory diagnosis of Chlamydia trachomatis infections by Max A Chernesky

“…Most invasive specimens, such as cervical or urethral swabs, may be collected for culture, antigen or nucleic acid detection. Noninvasive samples such as first-void urine and vaginal swabs can be easily collected by the patient; these samples must be tested by more sensitive nucleic acid amplification tests. …”
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Recent progress in prompt molecular detection of liquid biopsy using Cas enzymes: innovative approaches for cancer diagnosis and analysis by Zahra Farshchian Yazdi, Shahrzad Roshannezhad, Samaneh Sharif, Mohammad Reza Abbaszadegan

“…Among diagnostic methods, those relying on nucleic acid detection are highly sensitive and specific. …”
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Investigation of west nile virus infection in brown bears (ursus arctos) in turkey by Yakup Yıldırım, Fethiye Çöven, Erdoğan Uzlu, Volkan Yılmaz, Emrah Çoban, Ayşegül Çoban, Çağan Hakkı Şekercioğlu

“…Reverse transcription polymerase chain reaction (RT-PCR) technique was used to determine the presence of West Nile Virus nucleic acid.<p> <b>Results:</b> Seropositivity rate was detected to be zero % and West Nile virus nucleic acid was not found in samples.…”
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Effect of wet dressing of Chinese herbs on subcutaneous induration caused by subcutaneous injection of Azacitidine (中药湿敷改善阿扎胞苷皮下注射所致皮下硬结的效果观察)... by ZHAO Jialu (赵佳璐), WANG Huaxin (王华新), LI Ye (李野)

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