Detection of Delafloxacin Resistance Mechanisms in Multidrug-Resistant <i>Klebsiella pneumoniae</i> by András Kubicskó, János Juhász, Katalin Kamotsay, Dora Szabo, Béla Kocsis

“…<b>Background:</b> In this study, the mechanisms implicated in delafloxacin resistance in <i>Klebsiella pneumoniae</i> strains were investigated. Delafloxacin is a novel, broad-spectrum fluoroquinolone that has been approved for clinical application. …”
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Infusion of Autologous Retrodifferentiated Stem Cells into Patients with Beta-Thalassemia by Ilham Saleh Abuljadayel, Tasnim Ahsan, Huma Quereshi, Shakil Rizvi, Tamseela Ahmed, Sabiha Mirza Khan, Jawaid Akhtar, Ghazi Dhoot

“…No adverse side effects in response to the infusion of autologous RSC were noted.This novel clinical procedure may profoundly modify the devastating course of many genetic disorders in an autologous setting, thus paving the way to harnessing pluripotency from differentiated cells to regenerate transiently an otherwise genetically degenerate tissue such as thalassemic blood.…”
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How to convert a 3D printer to a personal automated liquid handler for life science workflows by Dulguunnaran Naranbat, Benjamin Phelps, John Murphy, Anubhav Tripathi

“…The PALH system was evaluated through common life science assays, including preparing real-time PCR samples, end-point PCR with novel pipet-based downstream purification, and genomic DNA extraction from peripheral whole blood. …”
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Lymph Node Adiposity and Metabolic Dysfunction-Associated Steatotic Liver Disease by Jessica M. Rubino, Natalie Yanzi Ring, Krishna Patel, Xiaoqing Xia, Todd A. MacKenzie, Roberta M. diFlorio-Alexander

“…Lymph node adiposity (LNA) is a novel marker of adiposity identified within axillary lymph nodes on screening mammography. …”
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Circulating miRNAs as Biomarkers for Prostate Cancer Diagnosis in Subjects with Benign Prostatic Hyperplasia by Wei Jin, Xiang Fei, Xia Wang, Fangjie Chen, Yan Song

“…Identifying microRNAs (miRNAs) in subjects’ blood with various malignancies means that they can serve as novel biomarkers for prostate cancer (PCa) diagnosis. …”
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Dietary Fiber-Rich <i>Spartina anglica</i> Improves Intestinal Health and Antioxidant Capacity of Zhedong White Geese by Xiao Zhou, Li Wang, Jiuli Dai, Huiyan Jia, Kai Shi, Jian Zhao, Shufang Chen

“…This study investigates the integration of SA as a novel dietary ingredient for Zhedong white geese, with a specific focus on evaluating its effects on growth performance, nutrient digestibility, antioxidant capacity, intestinal health, and cecal microbiota composition. …”
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Corticospinal Tract Wiring and Brain Lesion Characteristics in Unilateral Cerebral Palsy: Determinants of Upper Limb Motor and Sensory Function by Cristina Simon-Martinez, Ellen Jaspers, Lisa Mailleux, Els Ortibus, Katrijn Klingels, Nicole Wenderoth, Hilde Feys

“…Sensory function was predicted by the combination of a large and later lesion and an ipsilateral or bilateral CST wiring, which led to increased sensory deficits (p<0.05). These novel insights contribute to a better understanding of the underlying pathophysiology of UL function and may be useful to delineate individualized treatment strategies.…”
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The Prognostic Value of Peripheral Blood Inflammatory Markers in Hepatocellular Carcinoma Treated with Lenvatinib Combined with PD-1 Inhibitors by Xin Y, Liu N, Peng G, Huang X, Cao X, Zhou X

“…The factors related to treatment response and survival outcomes were analyzed through logistic regression and Cox regression, respectively. A novel preoperative prognostic nomogram was constructed based on inflammatory indexes, and the predictive efficacy of the nomogram and BCLC staging was compared by the area under the ROC curve.Results: 156 eligible patients with unresectable HCC were included, with median OS and PFS of 23.8 and 11.5 months, respectively, and ORR of 48.7%. …”
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Leveraging Deep Learning and Multimodal Large Language Models for Near-Miss Detection Using Crowdsourced Videos by Shadi Jaradat, Mohammed Elhenawy, Huthaifa I. Ashqar, Alexander Paz, Richi Nayak

“…This study introduces a novel AI-based framework designed to detect and analyze near-miss and crash events in crowdsourced dashcam footage. …”
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Efficient Method for Robust Backdoor Detection and Removal in Feature Space Using Clean Data by Donik Vrsnak, Marko Subasic, Sven Loncaric

“…Furthermore, detection methods that rely on the input data suffer from the fact that they are constrained to the modality of the input and cannot apply to different modalities. In this work, a novel method for backdoor detection and removal for classification tasks using features extracted by the attacked model called FEAT-IN is proposed. …”
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Antioxidant Stability of Moringa Leaves Extract Powders Obtained by Cocrystallization, Vacuum Drying, and Plating by Bambang Nurhadi, Fatsyarien Citra Angiputri, Robi Andoyo, Riksfardini Annisa Ermawar, Rudy Adi Saputra

“…Cocrystallization and vacuum drying are two relatively novel, less common techniques offering a simpler and more cost-effective method, but their effect on the antioxidant stability of moringa leaves extract has not yet been studied. …”
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Identification of prognostic biomarker of non-small cell lung cancer based on mitochondrial permeability transition-driven necrosis-related genes and determination of anti-tumor ef... by Zhifei Ma, Wen Chen, Aiping Zhang, Xiaokang Shen, Lin Zheng

“…Recent evidence suggests that activation of MPTND can effectively induce cancer cell death and may represent a novel therapeutic strategy for cancer. Yet, the role of MPTDN-related genes in non-small cell lung cancer (NSCLC) remains unrevealed. …”
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Impact of Cyclosporine A on Cognitive Functions and Neuronal Oxidative Stress, Apoptosis and Inflammatory Markers in Rats by Awyed Batah Almutairi, Abdulaziz Arif A. Alshammari, Arshad Husain Rahmani, Ali Yousif Babiker, Long Chiau Ming, Maha A. Aldubayan, Ahmad H. Alhowail, Vasudevan Mani

“…Behavioural assessments included the elevated plus maze (EPM) and novel object recognition (NOR) tests used to evaluate memory capabilities and recognition memory respectively, and the Y-maze assessed the exploration of a new environment and navigational skills. …”
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The antibiofilm effect and mechanism of silver nanowire-modified glass ionomer cement against multi-species oral biofilm by Tiantian Guo, Dai Wang, Sherry Shiqian Gao

“…Abstract Background To investigate the antibiofilm effect and mechanism of the silver nanowire (AgNW)-modified glass ionomer cement (GIC) against multi-species oral biofilm, and to examine the mechanical and biochemical properties of this novel GIC material. Methods Conventional GIC was incorporated with different concentrations of AgNW and silver nanoparticles (AgNP). …”
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Elucidating the emotional persona in the Romanian university students’ academic discourse: a corpus-based exploration by Diana Paula Dudău, Diana Paula Dudău, Madalina Chitez, Florin Alin Sava

“…In contrast, the Romanian corpus, characterized by a third cluster, presents less clear-cut patterns: humanities texts span both emotionally expressive and neutral tones, while research and academic papers frequently exhibit an achievement-oriented or entrepreneurial style, though a significant subset also reflects a highly disengaged profile.DiscussionBy integrating machine learning, network analysis, and automatic language analysis, this study offers a novel perspective on how language, genre, and discipline-specific conventions shape emotional expression in academic writing. …”
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Application of Magnetic Aquatic Plant Biochar for Efficient Removal of Antimony from Water: Adsorption Properties and Mechanism by Luyi Nan, Yuting Zhang, Min Liu, Liangyuan Zhao, Yuxuan Zhu, Xun Zhang

“…In the present research, a novel type of efficient adsorbent material for the magnetic recovery of Sb was proposed: the magnetic aquatic plant biochar. …”
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Modeling vegetation density with remote sensing, normalized difference vegetation index and biodiversity plants in watershed area by R.Z. Ekaputri, T. Hidayat, H.K. Surtikanti, W. Surakusumah

“…Spatial data encompass maps and field data.FINDING: By employing normalized difference vegetation index data, the study pioneers a novel approach to environmental monitoring, setting an example for effective resource management and ecological conservation in watershed regions. …”
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Exploring the Diversity and Ecological Dynamics of Palm Leaf Spotting Fungi—A Case Study on Ornamental Palms in Portugal by Diana S. Pereira, Alan J. L. Phillips

“…The taxonomic structures of the PLSF contrasted markedly from tropical palm fungi, especially in the prevalence of pleosporalean coelomycetes of the <i>Didymellaceae</i> and <i>Phaeosphaeriaceae</i>, including recently introduced or not previously documented genera on <i>Arecaceae</i>. This novel assemblage suggests that climatic constraints shape the structure of palm fungal communities, resulting in distinctive temperate and tropical assemblages. …”
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Sustainable and smart multi-analyte HPTLC determination of tolperisone HCl together with three pain killers using smartphone camera as a detector: Comparative study with benchtop d... by Mohamed Rizk, Emad Ramzy, Safaa Toubar, Amr M. Mahmoud, Marwa I. Helmy

“…In this study, we developed a novel and cost-effective method for the simultaneous determination of four drugs (Tolperisone HCl (TOLP), aceclofenac(ACEC), Paracetamol (PARA), and etodolac (ETOD)). …”
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Predicting Outcomes in Esophageal Squamous Cell Carcinoma Using scRNA‐Seq and Bulk RNA‐Seq: A Model Development and Validation Study by Jiaqi Zhang, Shunzhe Song, Yuqing Li, Aixia Gong

“…Therefore, calculating the metabolic score based on the glucose metabolic gene sets may bring some novel insights, enabling the prediction of prognosis and the identification of treatment choices for ESCC. …”
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