Engineered testbeds for investigating syringe injection performance in human factors studies by Andrew Pack, Sabrina Su, Frank A. Drews, Amrish Chourasia, Kevin Cluff, Joy Guerrieri, Jungkyu Kim

“…The presented systems offer valuable tools for future Human Factors studies, enabling quantification of user strength during syringe injections across various groups, including those with hand impairments. Précis: Two novel testing systems mimicking variable viscosity injections through fluidic or mechanical property variation enable the quantification of user strength in Human Factors studies and inform syringe design and viscosity limits.…”
Get full text

SkelETT—Skeleton-to-Emotion Transfer Transformer by Pedro Victor Vieira Paiva, Josue Junior Guimaraes Ramos, Marina Gavrilova, Marco Antonio Garcia de Carvalho

“…In this paper, we introduce a novel approach to emotion recognition by pre-training a transformer model on a large dataset of unsupervised human skeleton representations and subsequently fine-tuning it for emotion classification. …”
Get full text

Hydrogen-Bonded Di(hydroperoxy)alkane Adducts of the Type Cy₃P=O·(HOO)₂CHR (R = Alkyl) by Rahym Ashirov, Maya Todorovic, Nattamai Bhuvanesh, Janet Blümel

“…Five representatives of a novel type of di(hydroperoxy)alkane adducts of phosphine oxides have been synthesized and fully characterized, including their solubility in organic solvents. …”
Get full text

Value of transabdominal ultrasonography for diagnosing functional constipation in children: a systematic review and meta-analysis by Duc Long Tran, Phu Nguyen Trong Tran, Paweena Susantitaphong, Phichayut Phinyo, Palittiya Sintusek

“…Transabdominal ultrasonography is increasingly used as a novel modality for detecting pediatric functional constipation (FC). …”
Get full text

How far? Travel burdens for children admitted to hospitals in the Western Cape Province of South Africa by M Richards, D le Roux, D Pienaar

“…Conclusion: Using a large health dataset, this study demonstrates in a novel way for South Africa, the distances children travel to access admission facilities. …”
Get full text

Brief exposure to (-) THC affects zebrafish embryonic locomotion with effects that persist into the next generation by Md Ruhul Amin, Lakhan Khara, Joshua Szaszkiewicz, Andrew M. Kim, Trevor J. Hamilton, Declan W. Ali

“…Adult zebrafish tested in the open field test and novel object approach test demonstrated no differences in locomotion, anxiety-like behavior, nor boldness, compared to controls. …”
Get full text

An In Vitro Model of Diabetic Retinal Vascular Endothelial Dysfunction and Neuroretinal Degeneration by Qiyun Wang, Xinyuan Zhang, Kaiyue Wang, Ling Zhu, Bingjie Qiu, Xiaosi Chen, Xiao Lin, Yao Nie

“…Proper in vitro DR models are crucial for exploring pathophysiology and identifying novel therapeutic targets. This study establishes a rational in vitro diabetic retinal neuronal-endothelial dysfunction model and a comprehensive downstream validation system. …”
Get full text

Advancing GIS-based suitability analysis of BtX, PtX, PBtX, and eBtX facilities using the fuzzy analytic hierarchy process by Marcel Dossow, Mengxi Chen, Hartmut Spliethoff, Sebastian Fendt

“…To address the urgent need for sustainable fuel production, this study proposes a novel methodology that integrates Geographic Information Systems (GIS) and Multi-Criteria Decision Analysis (MCDA) techniques to identify optimal sites for Biomass-to-X (BtX), Power-to-X (PtX), or hybrid (e-/PBtX) facilities. …”
Get full text

Modeling and Analysis of Rice Root Water Uptake under the Dual Stresses of Drought and Waterlogging by Jie Huang, Wei Dong, Luguang Liu, Tiesong Hu, Shaobin Pan, Xiaowei Yang, Jianan Qin

“…Addressing this as our objective; we modified the Feddes root water-uptake model by revising the soil water potential response threshold and by introducing a novel method to calculate root water-uptake rates under simultaneous drought and waterlogging stresses. …”
Get full text

The relationships among food neophobia, mediterranean diet adherence, and eating disorder risk among university students: a cross-sectional study by Nilufer Ozkan, Fatma Hazan Gul

“…Abstract Background Food neophobia, characterized by the fear of unfamiliar foods, can be influenced by environmental, cultural, and genetic factors, leading to decreased consumption of novel or diverse foods. Understanding the impact of Mediterranean diet adherence and eating disorders on dietary behaviors is crucial, particularly for young adults who are developing lifelong eating patterns. …”
Get full text

DNM3OS Enhances the Apoptosis and Senescence of Spermatogonia Associated with Nonobstructive Azoospermia by Providing miR-214-5p and Decreasing E2F2 Expression by Rui Hua, Qingjun Chu, Feiyan Guo, Qinjie Chen, Maocai Li, Xuan Zhou, Yongtong Zhu

“…DNM3OS was found to regulate the apoptosis and senescence of spermatogonia by providing miR-214-5p and decreasing E2F2 expression, suggesting it as a novel target for gene therapy of male infertility.…”
Get full text

Biaxial Flexural Strength and Vickers Hardness of 3D-Printed and Milled 5Y Partially Stabilized Zirconia by Sebastian Hetzler, Carina Hinzen, Stefan Rues, Clemens Schmitt, Peter Rammelsberg, Andreas Zenthöfer

“…PZ samples were made from a novel ceramic suspension via digital light processing and divided into three subgroups: PZ-HN-ZD (horizontal nesting, printed with Zipro-D Dental), PZ-VN-Z (vertical nesting, printed with Zipro-D Dental) and PZ-VN-Z (vertical nesting, printed with Zipro Dental). …”
Get full text

Augmented Reality Navigation System Enhances the Accuracy of Spinal Surgery Pedicle Screw Placement: A Randomized, Multicenter, Parallel‐Controlled Clinical Trial by Yichao Ma, Jiangpeng Wu, Yanlong Dong, Hongmei Tang, Xiaojun Ma

“…This study aims to evaluate the differences in accuracy between novel AR‐guided pedicle screw insertion and conventional surgery techniques. …”
Get full text

Long Noncoding RNA HCG9 Promotes Osteosarcoma Progression through RAD51 by Acting as a ceRNA of miR-34b-3p by Lu Wang, ShuangQing Li, Lin Qi, Lin Ling

“…We discovered that lncRNA HCG9 promoted the proliferation of osteosarcoma cells via suppressing miR-34b-3p. Our study provides novel biomarkers and potential therapeutic targets for osteosarcoma treatment.…”
Get full text

Identification of Cytosolic DNA Sensor cGAS-STING as Immune-Related Risk Factor in Renal Carcinoma following Pan-Cancer Analysis by Zheng Wu, Ying Lin, Li-Min Liu, Yan-Li Hou, Wei-Ting Qin, Lei Zhang, Shu-Heng Jiang, Qin Yang, Yong-Rui Bai

“…We constructed a cGAS-STING gene signature to predict survival and tumor immunity across human cancers, which can serve as a novel prognostic indicator and therapeutic target, especially in KIRC and KIRP.…”
Get full text

Quantitative analysis of amino acid excretion by Methanothermobacter marburgensis under N2-fixing conditions by Barbara Reischl, Benjamin Schupp, Hayk Palabikyan, Barbara Steger-Mähnert, Christian Fink, Simon K.-M. R. Rittmann

“…To quantify N2-fixation rates in a mass balance setting a novel method has been established. The method utilizes the pressure drop below a certain threshold pressure in closed batch cultivation mode – the threshold pressure for N 2 -fixation (THpN2fix). …”
Get full text

circCOL1A1 Promotes the Progression of Gastric Cancer Cells through Sponging miR-145 to Enhance RABL3 Expression by Yue Ma, Yanyi Ren, Huitao Wen, Chengcheng Cui

“…Our study identified circCOL1A1 as a novel oncogenic circRNA and will provide more information for gastric cancer therapy.…”
Get full text

Safety, Tolerability and Pharmacokinetic-Pharmacodynamic Relationship of NX210c Peptide in Healthy Elderly Volunteers: Randomized, Placebo-Controlled, Double-Blind, Multiple Ascend... by Annette Janus, Daniël Dumas, Juliette Le Douce, Sébastien Marie, Giuseppe Pasculli, Pauline Bambury, Sighild Lemarchant, Philip Kremer, Yann Godfrin

“…The effects of NX210c on claudin-5 and biomarkers influencing BBB integrity—and the overarching brain protection it offers—provide a novel therapeutic strategy targeting an underlying driver of neurodegenerative conditions for which disease-modifying treatments are limited or not available.…”
Get full text

High Body Roundness Index Is Associated With Unhealthy Sleep Patterns: Insights From NHANES (2007–2014) by Pingchuan Liu, Yuding Luo, Xing He, Jiali Zhang, Fanzhou Ren, Bingyang Zhang, Bo Zheng, Jian Wang

“…However, research investigating sleep patterns in relation to novel anthropometric indices is limited. Therefore, we conducted a cross‐sectional analysis of data from the National Health and Nutrition Examination Survey (NHANES) from 2007 to 2014 to examine the relationship between the body roundness index (BRI) and unhealthy sleep patterns. …”
Get full text

Association between triglyceride-glucose index and clinical outcomes among patients with chronic kidney disease: a meta-analysis by Jinli Tuo, Zhong Li, Linshen Xie

“…Conclusion High TyG index predicts poor clinical outcomes and might serve as a novel prognostic indicator among CKD patients. However, more studies are still needed to verify above findings.…”
Get full text