Propofol Regulates ER Stress to Inhibit Tumour Growth and Sensitize Osteosarcoma to Doxorubicin by Hua Wei, Xinhui Du, Huaping Zhao, Peipei Sun, Jianjun Yang

“…Our findings provided a novel option in osteosarcoma therapy.…”
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A First Application of the Backward Technique in Social Sciences: Exploring Demographic Noise in a Model with Three Personality Types by Roberto Macrelli, Margherita Carletti, Vincenzo Fano

“…In this study, starting from a predictable, deterministic system, we move beyond biology and explore the effects of demographic noise in a novel model arising from the social sciences. Our field will be psychosocial, that is, the connections and processes that support social relationships between individuals. …”
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Gastrointestinal Bleeding in COVID-19 Patients: A Systematic Review with Meta-Analysis by Giovanni Marasco, Marcello Maida, Gaetano Cristian Morreale, Massimo Licata, Matteo Renzulli, Cesare Cremon, Vincenzo Stanghellini, Giovanni Barbara

“…The novel coronavirus disease 2019 (COVID-19) has been reported to affect the gastrointestinal system with a variety of symptoms, including bleeding. …”
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Kaposi's sarcoma-associated herpesvirus (KSHV) gB dictates a low-pH endocytotic entry pathway as revealed by a dual-fluorescent virus system and a rhesus monkey rhadinovirus expres... by Shanchuan Liu, Sarah Schlagowski, Anna K Großkopf, Natalia Khizanishvili, Xiaoliang Yang, Scott W Wong, Elina M Guzmán, Marija Backovic, Stefano Scribano, Arne Cordsmeier, Armin Ensser, Alexander S Hahn

“…Together with a hybrid RRV expressing KSHV gB and classical fusion assays, these novel tools identify low vesicle pH as an endocytotic trigger for KSHV membrane fusion.…”
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Clinical, biochemical and molecular characteristics of classic homocystinuria in Saudi Arabia and the impact of newborn screening on prevention of the complications: A tertiary cen... by Ahmed Sarar Mohamed, Talal AlAnzi, Amal Alhashem, Hadeel Alrukban, Fahad Al Harbi, Sarar Mohamed

“…Seven previously reported variants were detected in this cohort and one novel variant was found in three patients (c.828+2‐828+ 3 delins ACACTTGCATCC, p.?). …”
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The role of SASP in ischemic stroke: a deep dive into cellular mechanisms by Dong Xie, Yang Liu, Fang-Biao Xu, Jin-Sheng Zhang

“…Ccl3 and Lcp1 might potentially modulate IS progression by influencing SASP, proffering novel prospects for IS clinical diagnosis and treatment.…”
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Development of a Three-Stage Hybrid Model by Utilizing a Two-Stage Signal Decomposition Methodology and Machine Learning Approach to Predict Monthly Runoff at Swat River Basin, Pak... by Muhammad Sibtain, Xianshan Li, Ghulam Nabi, Muhammad Imran Azam, Hassan Bashir

“…To overcome this difficulty, this paper proposes a three-stage novel hybrid model, namely, CVS (CEEMDAN-VMD-SVM), by coupling the support vector machine (SVM) with a two-stage signal decomposition methodology, combining complete ensemble empirical decomposition with additive noise (CEEMDAN) and variational mode decomposition (VMD), to obtain inclusive information of the runoff time series. …”
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Optimizing Healthcare Expenditure for Spinal Cord Stimulation in Italy: The Value of Battery Longevity Improvement and a Direct-to-Implant Approach by Federica Tito, Gianfranco Sindaco, Simon Eggington, Elisa Tacconi, Francesca Borghetti, Mara Corbo, Gilberto Pari

“…The longer the device lasts, the lower mean total cumulative costs the patient will have, especially with regard to device replacement costs. With novel devices and specific programming settings, the lifetime cost per patient to a payer can be decreased without compromising the patient’s safety and positive clinical outcome. …”
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Studying the impact of zein microfibers on the physicochemical and microstructural properties of bi-gels based on ι-carrageenan hydrogels and beeswax oleogels by Mojtaba Rezaei, Sara Naji-Tabasi, Behrouz Ghorani, Bahareh Emadzadeh

“…This research presents a novel bi-gel system formed by combining zein microfiber -reinforced carrageenan hydrogels and beeswax oleogels. …”
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Development and performance evaluation of sustainable lightweight geopolymer based fireproofing coatings for steel construction by Zhenyu Huang, Yingwu Zhou, Hammad Salahuddin

“…This study developed a novel, sustainable, lightweight, and high-ductility fireproofing coating using granulated blast furnace slag (GBFS), fly ash microspheres (FAC), alkali activator, and polyethylene (PE) fiber as raw materials. …”
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Incompatible Aedes aegypti male releases as an intervention to reduce mosquito population-A field trial in Puerto Rico. by Liliana Sánchez-González, Jacob E Crawford, Laura E Adams, Grayson Brown, Kyle R Ryff, Mark Delorey, Jose Ruiz-Valcarcel, Nicole Nazario, Nexilianne Borrero, Julieanne Miranda, Sara N Mitchell, Paul I Howell, Johanna R Ohm, Charlie Behling, Brian Wasson, Craig Eldershaw, Bradley J White, Vanessa Rivera-Amill, Roberto Barrera, Gabriela Paz-Bailey

“…Our project underscores the challenges involved in large and complex field effectiveness assessments of novel vector control methods.…”
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Understanding human papillomavirus vaccine response and efficacy in people living with HIV: A systematic mixed studies review and meta-analysis. by Alvine M Akumbom, Alanna J Bergman, Howard Strickler, Chakra Budhathoki, Manka Nkimbeng, Raeven Grant, Nancy R Reynolds, Kawsar R Talaat

“…Precision medicine may offer novel alternatives for evaluating HPV vaccine efficacy in PWH.…”
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Human Brain Organoid: A Versatile Tool for Modeling Neurodegeneration Diseases and for Drug Screening by Cuili Ma, Hwanwook Seong, Xiaowei Li, Xiao Yu, Shunliang Xu, Yujing Li

“…As such, the organoids open a novel avenue for in vitro models of human disease, advantageous over the existing animal models. …”
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Every little helps: exploring meat and animal product consumption in the Tesco 1.0 dataset by Rakefet Cohen Ben-Arye, Christopher Bryant, Katharina Hofmann

“…The purpose of this paper is to add to knowledge on regional, seasonal, and sociodemographic variations in animal product consumption, as well as provide a valuable overview of animal product consumption using a novel data source that comprises actual purchase data rather than self-reported consumption.…”
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Effectiveness of pre-employment card policy on employment transition during covid-19: evidence from Indonesian dual labor market by Beni Teguh Gunawan, El Bram Apriyanto, Hennigusnia Hennigusnia, Ivan Lilin Suryono, Ardhian Kurniawati

“…This study introduces a novel perspective by employing a dual labor market approach, which highlights the distinct roles and interactions of formal and informal sectors in Indonesia’s labor market. …”
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Emerging Strategies in Cartilage Repair and Joint Preservation by Mircea Adrian Focsa, Sorin Florescu, Armand Gogulescu

“…Gene-editing tools like CRISPR/Cas9 have facilitated targeted cellular modifications, while novel biomaterials such as hydrogels, biodegradable scaffolds, and 3D-printed constructs have improved mechanical support and tissue integration. …”
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sORFdb – a database for sORFs, small proteins, and small protein families in bacteria by Julian M. Hahnfeld, Oliver Schwengers, Lukas Jelonek, Sonja Diedrich, Franz Cemič, Alexander Goesmann

“…Additionally, small protein families with Hidden Markov Models and information on taxonomic distribution and other physicochemical properties are available. In conclusion, the novel small protein database sORFdb is a specialized, taxonomy-independent database that improves the findability and classification of sORFs, small proteins, and their functions in bacteria, thereby supporting their future detection and consistent annotation. …”
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Optimal Information Hiding: Advanced Bitstream-Based Watermarking for Secure and Efficient Integration of Image Data in Digital Videos by null Ramyashree, Venugopala P. S., Raghavendra S., null Sarojadevi

“…To address this issue, we proposed a novel Bitstream video watermarking technique that integrates cutting-edge methodologies to seamlessly embed image data within digital videos. …”
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US-Japan Trade Relations Amid the Globalization Crisis by V. G. Shvydko

“…The rising confrontation between the United States and China amid the spread of novel coronavirus epidemic in early 2020 alleviated tensions over Japan-US trade issues by temporarily removing them from the focus of attention of the US presidential administra­tion. …”
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Metal oxides carbon xerogel nanocomposite for methanol oxidation fuel cell by Fatma Mohamed, Mohamed Shaban, Omnia M. Salem

“…This work used environmentally friendly materials, which presents a novel opportunity to enhance the efficiency of methanol oxidation via the utilization of affordable catalysts. …”
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