Microwave coprocessing of modafinil with Gelucire®: Thermal and compression characteristics by Derar Omari, Assayed Sallam, Iyad Rashid, Shereen M. Assaf, Faisal Akayleh, Khaldoun A. Al-Sou′od

“…These findings highlight the potential of microwave-assisted complexation as a novel approach to improve the pharmaceutical performance of BCS Class II drugs like modafinil. …”
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Gaining Insight into Operative Performance: Analysis of an Automated 360-Degree Feedback Tool Among Perioperative Staff by Stefanie J. Soelling, MD, MPH, Robert D. Sinyard, MD, Lauren Spigel, MPH, Max Riley, MD, Paul Gregory, PhD, Nick Perdomo, MS, Yves Sonnay, MScPH, Steven Yule, PhD, Steven J. Fishman, MD, Douglas S. Smink, MD, MPH, FACS

“…We sought to evaluate the overall findings and perceived value of a novel 360-degree feedback tool for surgeons from their operating room colleagues. …”
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In-vivo high-resolution χ-separation at 7T by Jiye Kim, Minjun Kim, Sooyeon Ji, Kyeongseon Min, Hwihun Jeong, Hyeong-Geol Shin, Chungseok Oh, Robert J. Fox, Ken E. Sakaie, Mark J. Lowe, Se-Hong Oh, Sina Straub, Seong-Gi Kim, Jongho Lee

“…To address these challenges, we developed a novel deep neural network, R2PRIMEnet7T, designed to convert a 7T R2* map into a 3T R2′ map. …”
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NavBLIP: a visual-language model for enhancing unmanned aerial vehicles navigation and object detection by Ye Li, Li Yang, Meifang Yang, Fei Yan, Tonghua Liu, Chensi Guo, Rufeng Chen

“…Additionally, these methods often fail to effectively integrate multimodal inputs, which restricts their adaptability and generalization capabilities when facing complex and diverse scenarios.MethodsTo address these challenges, we introduce NavBLIP, a novel visual-language model specifically designed to enhance UAV navigation and object detection by utilizing multimodal data. …”
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The Role of Caspase-4 and NLRP1 in MCF7 Cell Pyroptosis Induced by hUCMSC-Secreted Factors by Yang Jiao, Linlin Wang, Lin Lu, Jianjun Liu, Xin Li, Hongbo Zhao, Zongliu Hou, Bingrong Zheng

“…Mesenchymal stem cells (MSCs) are being widely investigated for the development of novel therapeutic approaches for different cancers, including breast cancer, the leading form of cancer in women. …”
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Esophageal Endoscopic Submucosal Dissection Assisted by an Overtube with a Traction Forceps: An Animal Study by Ken Ohata, Kuangi Fu, Eiji Sakai, Kouichi Nonaka, Tomoaki Tashima, Yohei Minato, Akiko Ohno, Takafumi Ito, Yosuke Tsuji, Hideyuki Chiba, Makoto Yamawaki, Hideyuki Hemmi, Teruo Nakaya, Junichi Fukushima, Nobuyuki Matsuhashi

“…To make it safer, we developed a novel method using overtube with a traction forceps (OTF) for countertraction during submucosal dissection. …”
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Kruppel-family zinc finger proteins as emerging epigenetic biomarkers in head and neck squamous cell carcinoma by Patrick Pearson, Kendra Smith, Nilita Sood, Elizabeth Chia, Alicia Follett, Michael B. Prystowsky, Simon Kirby, Thomas J. Belbin

“…Conclusions Both ZNF132 and ZNF154 represent novel clinically significant biomarkers in head and neck cancer with potential tumour suppressive properties. …”
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Self-Examination Low-Cost Full-Field Optical Coherence Tomography (SELFF-OCT) for neovascular age-related macular degeneration: a cross-sectional diagnostic accuracy study by Peter Koch, Inke König, Johann Roider, Jan Tode, Konstantine Purtskhvanidze, Claus von der Burchard, Helge Sudkamp, Cristoph Ehlken, Moritz Moltmann, Britta Heimes, Michael Münst, Malte vom Endt, Timo Kepp, Dirk Theisen-Kunde, Gereon Hüttmann

“…Objectives Self-Examination Low-Cost Full-Field Optical Coherence Tomography (SELFF-OCT) is a novel OCT technology that was specifically designed for home monitoring of neovascular age-related macular degeneration (AMD). …”
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Comparison of metabarcoding taxonomic markers to describe fungal communities in fermented foods by Rué, Olivier, Coton, Monika, Dugat-Bony, Eric, Howell, Kate, Irlinger, Françoise, Legras, Jean-Luc, Loux, Valentin, Michel, Elisa, Mounier, Jérôme, Neuvéglise, Cécile, Sicard, Delphine

“…Our results also emphasized the need for a dedicated database and enriched fungal-specific public databases with novel barcode sequences for 118 major species in food ecosystems. …”
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Familial Hypercholesterolemia: Genetics, Symptoms, Diagnosis and Treatment - A Literature Overview by Maciej Rutkiewicz, Sabina Przygodzka, Katarzyna Gadżała, Karolina Garbino, Katarzyna Brudniak, Antoni Szuścik, Magdalena Czyczerska

“…In most cases, one drug isn't enough, so therapy containing ezetimib is common. Novel treatments, including monoclonal antibodies (mAb), antisense oligonucleotides (ASO), and PCSK9- inhibitors nowadays, are used with greater frequency and better results, providing higher efficiency in achieving targets. …”
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Mechanisms underlying the effects of cyanogenesis on development and reproduction of Tetranychus urticae: Insights from enzyme activity and gene expression aspects by Mufeng Wu, Xiao Liang, Ying Liu, Chunling Wu, Xingkui An, Zihua Zhao, Guifeng Hao, Ijiti Oluwole Gregory, Zhihong Li, Qing Chen

“…The present findings can provide insight regarding reasonable utilization of toxic chemicals in pest management and creation of novel pest-resistant germplasm.…”
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Congenital muscular dystrophies and myopathies: the leading cause of genetic muscular disorders in eleven Chinese families by Bin Mao, Xiaoling Cai, Na Lin, Yulin Jiang, Na Hao, Yifang Dai, Danhua Guo, Deqin He, Huili Xue, Lingji Chen, Qianqian He, Min Zhang, Meihuan Chen, Hailong Huang, Liangpu Xu

“…Results Fourteen variants in nine genes (ATL1, LMNA, KLHL40, FKRP, DMD, ACTA1, MSTO1, RYR1 and LAMA2) associated with congenital muscular conditions were identified in the ten families mentioned above. Among them, five novel variants, c.1153_1155del in LMNA, c.577 A > G in ACTA1, c.694T > G in MSTO1, c.5938del in LAMA2, and a rare genome fusion ogm[GRCh38] fus(X; X)(p22.31;p21.1) involving DMD, have not been recorded in public databases to the best of our knowledge. …”
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Iranian Pediatric COVID-19 Epidemiology and Clinical Characteristics by Shahnaz Armin, Mohammadreza Mirkarimi, Zahra Pourmoghaddas, Marjan Tariverdi, Azadeh Jafrasteh, Noushin Marhamati, Armin Shirvani, Abdollah Karimi, Sedigheh Rafiei Tabatabaei, Roxana Mansour Ghanaei, SeyedAlireza Fahimzad, Fariba Shirvani, Seyedeh Mahsan Hoseini-Alfatemi

“…Thus, this study aims to evaluate the epidemiological features, laboratory and imaging findings, and the type of treatments in children with novel coronavirus 2019 (COVID-19). Method. This study is conducted from March 2020–March 2021 by using the medical records of hospitalized confirmed COVID-19 children younger than 18 years in five cities of Iran: Tehran, Ahwaz, Isfahan, Bandar-Abbas, and Khorramabad. …”
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Glycyrrhizinate Monoammonium Cysteine-Loaded Lipid Nanoparticles Allow for Improved Acute Liver Injury Therapy by Yunjie Xu, Pinghui Li, Shiran Sun, Yulin Chen, Lixia Feng, Dawei Jiang, Chidan Wan, Jianbo Li, Xiong Cai

“…<b>Conclusions:</b> Our results suggest that LNPs offer an enhanced therapeutic approach for ALI treatment, reducing the required drug dosage, and ⁶⁸Ga-FAPI PET/CT imaging provides a novel method for diagnosis and treatment assessment. …”
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Fully automatic reconstruction of prostate high-dose-rate brachytherapy interstitial needles using two-phase deep learning-based segmentation and object tracking algorithms by Mohammad Mahdi Moradi, Zahra Siavashpour, Soheib Takhtardeshir, Eman Showkatian, Ramin Jaberi, Reza Ghaderi, Bahram Mofid, Farzad Taghizadeh-Hesary

“…The current study proposed a novel methodology to automatically localize and reconstruct the prostate HDR-BT interstitial needles through the 3D CT images. …”
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Impact of solid fuel use on asthma prognosis and consistent peak expiratory flow changes: Evidence from China by Yuexi Chen, Shuojia Xie, Xirong Chen, Xiaowen Zhong, Linhang Yang, Weitong Lin, Junfeng Huang, Ruchong Chen

“…Conclusions: The research provided insights into the harmful effects of solid fuel dependence on asthma risk and outcomes, contributing novel evidence supporting this link. The results emphasize the necessity of curtailing solid fuel use to diminish potential health risks associated with asthma and to improve prognosis in affected individuals.…”
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Usefulness of the Hybrid RFR-FFR Approach: Results of a Prospective and Multicenter Analysis of Diagnostic Agreement between RFR and FFR—The RECOPA (REsting Full-Cycle Ratio Compar... by Juan Casanova-Sandoval, Diego Fernández-Rodríguez, Imanol Otaegui, Teresa Gil Jiménez, Marcos Rodríguez-Esteban, Kristian Rivera, Francisco Torres-Saura, Víctor Jiménez Díaz, Raymundo Ocaranza-Sánchez, Vicente Peral Disdier, Guillermo Sánchez-Elvira, Fernando Worner

“…The resting full‐cycle ratio (RFR) is a novel resting index which in contrast to the gold standard (fractional flow reserve (FFR)) does not require maximum hyperemia induction. …”
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Tracheal Resection for Critical Airway Obstruction in Morquio A Syndrome by Claire Frauenfelder, Elizabeth Maughan, Johnny Kenth, Reema Nandi, Simon Jones, Robert Walker, Bill Walsh, Nagarajan Muthialu, Iain Bruce, Richard Hewitt, Colin Butler

“…This addressing of tracheal/thoracic cage dimension mismatch represents a novel surgical treatment approach to an existing clinical paradigm and may be useful for other carefully selected individuals with MPS IVA. …”
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O Serogroup-Specific Touchdown-Multiplex Polymerase Chain Reaction for Detection and Identification of Vibrio cholerae O1, O139, and Non-O1/Non-O139 by Adisak Bhumiratana, Achiraya Siriphap, Nutsarin Khamsuwan, Jednipit Borthong, Kaknokrat Chonsin, Orasa Sutheinkul

“…A novel, sensitive locus-specific touchdown-multiplex polymerase chain reaction (TMPCR), which is based on two-stage amplification pertaining to multiplex PCR and conditional touchdown strategy, was used in detecting and differentiating Vibrio cholerae serogroups. …”
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A comparative bio-mechanical performance assessment of additively manufactured bone scaffolds using different beta Ti alloys and Gyroid based cellular structure by Mudassar Rehman, Yanen Wang, Kashif Ishfaq, Ray Tahir Mushtaq, Aqib Mashood Khan, Mohammed Alkahtani, Aamer Nazir, Maimoona Afzal

“…An exponential rise in demand for artificial implants has emphasized the need for novel biomaterials with good biocompatibility and mechanical properties comparable to human cortical and cancellous bone, to mitigate stress shielding and other post implantation challenges. …”
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