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12521
Four Decades of <i>Bacillus</i> Biofertilizers: Advances and Future Prospects in Agriculture
Published 2025-01-01“…We segmented the research timeline into three distinct phases, each marked by varying growth rates and research foci. This paper presents novel insights into the geographical and institutional distributions of research, highlighting the predominant role of developing countries in advancing <i>Bacillus</i>-based technologies. …”
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12522
Event-Based Slip Estimation Framework for Space Rovers Traversing Soft Terrains
Published 2025-01-01“…This paper presents a novel event-based longitudinal slip estimation framework designed to operate in low-light conditions. …”
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12523
Advanced Optimization Algorithm Combining a Fuzzy Inference System for Vehicular Communications
Published 2025-01-01“…This work introduces a novel optimization algorithm approach called the fuzzy inference reinforcement learning (FIRL) sequence for adaptive parameter configuration in cellular vehicle-to-everything (C-V2X) mode-4 communication networks. …”
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12524
Real-time detection of road surface friction coefficient: A new framework integrating diffusion model and Transformer in Transformer algorithms
Published 2025-02-01“…To obtain high-accuracy RSFC, this study proposes a novel real-time RSFC detection method that integrates a diffusion model with the Transformer-in-Transformer(TNT) model to detect RSFC from vehicle video pictures. …”
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12525
Blockade of TIPE2-Mediated Ferroptosis of Myeloid-Derived Suppressor Cells Achieves the Full Potential of Combinatory Ferroptosis and Anti-PD-L1 Cancer Immunotherapy
Published 2025-01-01“…These findings indicate that TIPE2 confers the ferroptosis sensitivity of MDSCs, and combining the targeting of the TIPE2 of MDSCs, ferroptosis therapy, and ICB is a novel therapeutic option for cancer treatment.…”
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12526
Essential Oils from Citrus Peels Promote Calcium Overload-Induced Calcicoptosis in U251 Cells
Published 2024-12-01“…These findings highlight the immense potential of CPEOs in healthcare and pharmaceutical applications by not only providing a scientific basis for the potential application of CPEOs in the treatment of glioblastoma but also offering new insights for the development of novel antitumor drugs.…”
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12527
ThermalGS: Dynamic 3D Thermal Reconstruction with Gaussian Splatting
Published 2025-01-01“…To address these challenges, we propose a novel dynamic thermal 3D reconstruction method, named ThermalGS, based on 3D Gaussian Splatting (3DGS). …”
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12528
Molecular assessment of splicing variants in a cohort of patients with inborn errors of immunity: methodological approach and interpretation remarks
Published 2025-01-01“…In total, 21 splicing variants were analyzed, 10 of which had previously been reported in the literature and 11 novel ones. Among the 23 patients, 16 showed variants at canonical splice sites. …”
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12529
Multidrug-Resistant Salmonella enterica Serovar Rissen Clusters Detected in Azores Archipelago, Portugal
Published 2019-01-01“…We also investigated the genetic basis driving the observed multidrug resistance. By integrating 60 novel genomes with all publicly available serovar Rissen genomes, we observed a low degree of genetic diversity within this serovar. …”
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12530
ANN-based software cost estimation with input from COCOMO: CANN model
Published 2025-02-01“…This research aims to identify the factors that influence the software effort estimation using the constructive cost model (COCOMO), and artificial neural networks (ANN) model by introducing a novel cost estimation approach, COCOMO-ANN (CANN), utilizing a partially connected neural network (PCNN) with inputs derived from calibrated values of the COCOMO model. …”
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12531
Identification of Target Genes of Antiarrhythmic Traditional Chinese Medicine Wenxin Keli
Published 2020-01-01“…These findings provide novel insight into molecular mechanisms of WXKL in reducing the incidence of ventricular arrhythmia.…”
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12532
Gallium Sulfide-Immobilized Optical Fiber-Based SPR Sensor for Detection of Brilliant Blue Food Adulteration
Published 2024-01-01“…In this study, we present a novel gallium sulfide (GaS)-immobilized optical fiber SPR sensor designed for the rapid, real-time detection of BB synthetic dye. …”
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12533
Membrane-bound model of the ternary complex between factor VIIa/tissue factor and factor X
Published 2025-02-01“…This lipid dependence has made experimental characterization of the EC structure challenging. Using a novel computational methodology combining rigid-body protein-protein docking and extensive nonequilibrium molecular dynamics simulations in the explicit presence of a membrane, we developed, to our knowledge, the first atomic-level model of the EC, taking full account of the role of the membrane. …”
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12534
Predicting the clinical subcutaneous absorption rate constant of monoclonal antibodies using only the primary sequence: a machine learning approach
Published 2024-12-01“…Our model does not need clinically observed plasma concentration-time data; this is a novel capability not previously achieved in predictive pharmacokinetic models. …”
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12535
Mechanically powered negative pressure dressing reduces surgical site infection after stoma reversal
Published 2025-01-01“…However, use of this approach has not been widely adopted due to high cost of the devices. We present a novel approach to stoma closure in which a self-contained mechanically powered negative pressure dressing (MP-NPD) is applied to primarily closed stoma reversal wounds. …”
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12536
Combined effects of co-exposure to microcystin-LR and polystyrene microplastics on growth, brain pathology and thyroid hormone homeostasis in adult zebrafish
Published 2025-02-01“…The concurrent presence of algal blooms and microplastics pollution in natural water bodies poses a novel threat. However, the joint effects of microcystin-LR (MCLR) in combination with polystyrene microplastics (PSMPs) on the thyroid endocrine system of adult fish remains unclear. …”
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12537
Nomogram model and risk score predicting overall survival and guiding clinical decision in patients with Hodgkin’s lymphoma: an observational study using SEER population-based data...
Published 2022-06-01“…Patients with HL had good long-term outcomes but novel therapies are still in need for fewer complications.…”
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12538
Effects of genetic ablation and pharmacological inhibition of HuR on gene expression, iron metabolism, and hormone levels
Published 2025-01-01“…Conclusions These findings uncover novel posttranscriptional mechanisms governed by HuR and its inhibitor, elucidating pathways relevant to HuR-mediated regulation and molecular therapies aimed at targeting this protein.…”
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12539
The truth about co-benefits: a multidimensional feasibility assessment for thailand and beyond
Published 2025-01-01“…The framework offers a novel yet generalizable approach for bringing context-appropriate assessments of different dimensions of feasibility into the integrated assessment modelling that underpins work on co-benefits. …”
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12540
Time to HIV viral rebound and frequency of post-treatment control after analytical interruption of antiretroviral therapy: an individual data-based meta-analysis of 24 prospective...
Published 2025-01-01“…Abstract The only current strategy to test efficacy of novel interventions for sustained HIV control without antiretroviral therapy (ART) among people with HIV (PWH) is through an analytical treatment interruption (ATI). …”
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