A computational role of blood nanofluid induced by a stenosed artery with porous medium and thermophoretic particle deposition effects by Shivalila Hangaragi, N. Neelima, N. Beemkumar, Ankur Kulshreshta, Umair Khan, Noreen Sher Akbar, Mohammad Kanan, Mona Mahmoud

“…Deep learning models demonstrate significant efficacy in analyzing and predicting stenotic conditions. The novel outcomes of this research highlight the effectiveness of deep learning models in predicting and analyzing stenotic blood flow conditions, contributing to improved diagnostic approaches to improve the patient's healthcare and reduce the mortality rate.…”
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Circulating MicroRNAs in Elderly Type 2 Diabetic Patients by Giuseppina Catanzaro, Zein Mersini Besharat, Martina Chiacchiarini, Luana Abballe, Claudia Sabato, Alessandra Vacca, Paola Borgiani, Francesco Dotta, Manfredi Tesauro, Agnese Po, Elisabetta Ferretti

“…The circulating microRNAs (miRNAs) associated with type 2 diabetes (T2D) in elderly patients are still being defined. To identify novel miRNA biomarker candidates for monitoring responses to sitagliptin in such patients, we prospectively studied 40 T2D patients (age > 65) with HbA1c levels of 7.5–9.0% on metformin. …”
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Ginsenoside F1 administration promotes UCP1-dependent fat browning and ameliorates obesity-associated insulin resistance by Yuhan Meng, Weili Li, Chenxing Hu, Si Chen, Haiyang Li, Feifei Bai, Lujuan Zheng, Ye Yuan, Yuying Fan, Yifa Zhou

“…Using thermogenic protein uncoupling protein 1 (UCP1)-luciferase reporter assay, we identified ginsenoside F1 as a novel UCP1 activator in the ginsenosides library. …”
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State-of-Charge Estimation of Lithium-Ion Battery Pack Based on Improved RBF Neural Networks by Li Zhang, Min Zheng, Dajun Du, Yihuan Li, Minrui Fei, Yuanjun Guo, Kang Li

“…Simulation results show that generalization error of SOC estimation using the novel RBF neural network model is less than half of that using other methods. …”
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Downregulation of the immunoproteasome subunit PSMB8 attenuates sepsis-associated acute kidney injury through the NF-κB pathway by Min Li, Wenjia Tong, Chao Dai, Guoping Lu, Danqun Jin, Fang Deng

“…These findings reveal the pathogenic role of PSMB8 in AKI and suggest a novel therapeutic target for the condition.…”
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Early Detection of Multiwavelength Blazar Variability by Hermann Stolte, Jonas Sinapius, Iftach Sadeh, Elisa Pueschel, Matthias Weidlich, David Berge

“…For this purpose, we have developed a novel deep learning analysis framework, based on data-driven anomaly detection techniques. …”
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EMT-driven plasticity prospectively increases cell–cell variability to promote therapeutic adaptation in breast cancer by Lauriane Muller, Frédérique Fauvet, Christelle Chassot, Francesca Angileri, Angèle Coutant, Cyril Dégletagne, Laurie Tonon, Pierre Saintigny, Alain Puisieux, Anne-Pierre Morel, Maria Ouzounova, Pierre Martinez

“…Higher plasticity was not associated with a partial EMT status. Our results provide novel insights on how EMT-driven plasticity promotes a prospective diversification process increasing population phenotypic diversity, which can yield rare pre-adapted states before treatment. …”
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Valproic acid targets IDH1 mutants through alteration of lipid metabolism by Lubayna S. Elahi, Michael C. Condro, Riki Kawaguchi, Yue Qin, Alvaro G. Alvarado, Brandon Gruender, Haocheng Qi, Tie Li, Albert Lai, Maria G. Castro, Pedro R. Lowenstein, Matthew C. Garrett, Harley I. Kornblum

“…We conclude that targeting fatty acid metabolism through HDAC inhibition and/or FASN inhibition may be a novel therapeutic opportunity in IDH1 mutant gliomas.…”
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Temporally and Spatially Controlled Age-Related Prostate Cancer Model in Mice by Sen Liu, Keyi Shen, Zixuan Li, Seleste Rivero, Qiuyang Zhang

“…The viral delivery procedures strictly control the location and time of Pten knockout. This novel approach provides a powerful age-related murine model for PCa, emphasizing the effect of aging on prostate carcinogenesis.…”
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Metasurface higher-order poincaré sphere polarization detection clock by Hui Yang, Kai Ou, Qiang Liu, Meiyu Peng, Zhenwei Xie, Yuting Jiang, Honghui Jia, Xinbin Cheng, Hui Jing, Yueqiang Hu, Huigao Duan

“…We actualize this concept through a novel meta-device known as the metasurface photonics polarization clock, which offers an intuitive display of SoP using four distinct pointers. …”
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Rapid Screening and Quantitative Determination of Illegal Phosphodiesterase Type 5 Inhibitors (PDE-5i) in Herbal Dietary Supplements by Thi Oanh Nguyen, Cao-Son Tran, Thi Thu Hang Do, Thi Minh Hoa Nguyen, Quang-Dong Bui, Cao-Tien Bui, Hong-Ngoc Nguyen, Thu-Hien Dang, Viet-Chien Dinh, Thi Anh Huong Nguyen, Thi Hong Hao Le

“…Fourteen PDE-5i including conventional and novel analogous were detected and measured in eighteen food supplements and two formulation ingredient samples.…”
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Traditional Chinese Medicine Prescription Generation Model Based on Search Enhancement by ZHAO Zijuan, REN Xueting, SONG Kai, QIANG Yan, ZHAO Juanjuan, ZHANG Junlong

“…In order to solve these problems, a hybrid neural network architecture for TCM prescription generation—PreGenerator is proposed. With a novel hierarchical retrieval mechanism, the PreGenerator can automatically extract prescription and herbal templates to facilitate accurate clinical prescription generation. …”
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Study and application on the size effect and end effect of red sandstone mechanical properties by Feng Chen, Jinyang Du, Yanhong Du, Ruxuan Li, Chun’an Tang, Yishan Pan, Gen Li

“…This paper also designs a novel "enhance strength and reduce rockburst" negative Poisson’s ratio material pad based on the "cyclo-hoop effect" induced by the end effect, aiming to improve the strength of compressed components and reduce the intensity of energy release during failure. …”
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Remotely‐Sensed Game Trails Are a Behavioral Footprint That Explains Patterns of Herbivore Habitat Use by Keenan Stears, Melissa H. Schmitt, Mike J. Peel, Tsumbedzo Ramalevha, Douglas J. McCauley, Dave I. Thompson, Deron E. Burkepile

“…Ultimately, we show that game trails are a novel data source that can be used to identify broadly‐occurring patterns of herbivore habitat use over large spatial scales.…”
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Ground-based Reconnaissance Observations of 21 Exoplanet Atmospheres with the Exoplanet Transmission Spectroscopy Imager by Ryan J. Oelkers, Luke M. Schmidt, Erika Cook, Mary Anne Limbach, D. L. DePoy, J. L. Marshall, Jimmy Ardoin, Mitchell Barry, Evan Batteas, Alexandra Boone, Brant Conway, Silvana Delgado Adrande, John D. Dixon, Enrique Gonzalez-Vega, Alexandra Guajardo, Landon Holcomb, Christian Lambert, Shravan Menon, Divya Mishra, Jacob Purcell, Zachary Reed, Nathan Sala, Noah Siebersma, Nhu Ngoc Ton, Raenessa M. L. Walker, Z. Franklin Wang, Kaitlin Webber

“…ETSI measurements are mostly free of systematics through the use of a novel observing technique called common-path multiband imaging (CMI), which has been shown to achieve photometric color precision on par with space-based observations (300 ppm or 0.03%). …”
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Towards a Rational Design of an Asymptomatic Clinical Herpes Vaccine: The Old, the New, and the Unknown by Aziz Alami Chentoufi, Elizabeth Kritzer, David M. Yu, Anthony B. Nesburn, Lbachir BenMohamed

“…These asymptomatic epitopes will provide a solid foundation for the development of novel herpes epitope-based vaccine strategy. Here we provide a brief overview of past clinical vaccine trials, outline current progress towards developing a new generation “asymptomatic” clinical herpes vaccines, and discuss future mucosal “asymptomatic” prime-boost vaccines that could optimize local protective immunity.…”
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Circular RNA ITCH Is a Tumor Suppressor in Clear Cell Renal Cell Carcinoma Metastasis through miR-106b-5p/PDCD4 Axis by Ping Gao, Yong Huang, Yanmei Hou, Qian Li, Haimei Wang

“…Conclusively, circ-ITCH suppresses ccRCC metastasis by enforcing PDCD4 expression through binding miR-106b-5p. circ-ITCH may function as a novel diagnostic target to suppress ccRCC metastasis.…”
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Photoplethysmography based psychological stress detection with pulse rate variability feature differences and elastic net by Fenghua Li, Peida Xu, Shichun Zheng, Wenfeng Chen, Yang Yan, Suo Lu, Zhengkui Liu

“…In this study, we took a novel approach of incremental pulse rate variability and elastic-net regression in predicting mental stress. …”
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Dynamic response of aerodynamic flutter of blooie line during gas drilling in mountain areas by Dianchen Liu, Peng Yang, Ke Deng, Shijie Tian, Hai Yan, Hongtao Li

“…To address the challenge of blockage on the flutter, novel tank equipment is designed to effectively manage the sudden ejection of massive cuttings, aiming to prevent abrupt blockages in the blooie line during the drilling process. …”
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Classification of Strawberry Maturity Stages and Varieties Using Neural Networks Based on Volatile Organic Compounds by Jing Huang, Xuenan Zhang, Hang Yang, Zhenbiao Li, Zhengfang Xue, Qingqing Wang, Xinyuan Zhang, Shenghua Ding, Zisheng Luo, Yanqun Xu

“…This study developed a novel classification workflow using strawberry VOC profiles and machine learning (ML) models for precise fruit classification. …”
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