Insulin-Like Growth Factor I Prevents Cellular Aging via Activation of Mitophagy by Xuwei Hou, Zhaohui Li, Yusuke Higashi, Patrice Delafontaine, Sergiy Sukhanov

“…Our data suggest that activation of IGF-1 signaling is a novel potential strategy to activate mitophagy and slow cellular aging.…”
Get full text

Pretransplant Immune- and Apoptosis-Related Gene Expression Is Associated with Kidney Allograft Function by Dorota Kamińska, Katarzyna Kościelska-Kasprzak, Paweł Chudoba, Oktawia Mazanowska, Mirosław Banasik, Marcelina Żabinska, Maria Boratyńska, Agnieszka Lepiesza, Agnieszka Gomółkiewicz, Piotr Dzięgiel, Marian Klinger

“…The pretransplant IFNG and CASP3 and FAS and IL-18 genes’ expression in the recipients’ peripheral blood is the possible candidate for novel biomarker of short- and long-term allograft function.…”
Get full text

CCL5 Induces a Sarcopenic-like Phenotype via the CCR5 Receptor by Francisco Aguirre, Franco Tacchi, Mayalen Valero-Breton, Josué Orozco-Aguilar, Sabrina Conejeros-Lillo, Josefa Bonicioli, Renata Iturriaga-Jofré, Daniel Cabrera, Jorge A. Soto, Mauricio Castro-Sepúlveda, Marianny Portal-Rodríguez, Álvaro A. Elorza, Andrea Matamoros, Felipe Simon, Claudio Cabello-Verrugio

“…In conclusion, we report for the first time that CCL5 is a novel myokine that exerts a sarcopenic-like effect through the CCR5 receptor.…”
Get full text

C5a-C5aR1 axis mediates lung inflammation and fibrosis induced by single-walled carbon nanotubes via promoting neutrophils recruitment by Jiaojiao Zhu, Xiang Zhang, Lanlan Li, Hongxu Yang, Hang Liu, Danyang Wu, Zikai Liu, Bin Liu, Tong Shen

“…In conclusion, our study provides novel insights into the underlying biological mechanism that C5a-C5aR1 axis regulates neutrophils recruitment-mediated lung injury induced by SWCNT, may help to develop therapeutic strategies for SWCNT-provoked lung injury.…”
Get full text

Beclin 1-Mediated Autophagy Is Potentiated by an Interaction with the Neuronal Adaptor FE65 by Wai Wa Ray Chan, Jessica Chow, Dennis Dik-Long Chau, Yuqi Zhai, Kwok-Fai Lau

“…Together, we have identified FE65 as a novel Beclin 1 interactor, and this interaction potentiates autophagy.…”
Get full text

Comprehensive performance evaluation of satellite-based and reanalysis rainfall estimate products in Ethiopia: For drought, flood, and water resources applications. by Desta Yoseph Wodebo, Assefa M Melesse, Tekalegn Ayele Woldesenbet, Kirubel Mekonnen, Ahmed Amdihun, Diriba Korecha, Hailay Zeray Tedla, Gerald Corzo, Asaminew Teshome

“…This study offers multiple novel perspectives for selecting location-specific suitable rainfall products as decision-support information for water resources, flood risk management, and drought monitoring in Ethiopia. …”
Get full text

The Efficient Integration of Dust and Numerical Weather Prediction for Renewable Energy Applications by Xi Chen, Mei Chong, Shian‐Jiann Lin, Zhi Liang, Paul Ginoux, Yuan Liang, Bihui Zhang, Qian Song, Shengkai Wang, Jiawei Li, Yimin Liu

“…Using iDust, global 12.5‐km 10‐day hourly dust storm forecast simulations initiated at 00UTC can produce results by 06UTC, enabling timely forecasting of severe dust storms with concentrations exceeding 1,000 μg/m3. This novel capability of iDust can meet the urgent forecasting needs of the renewable energy industry for extreme dust conditions, supporting the green energy transition.…”
Get full text

A Facile Electrode Modification Approach Based on Metal-Free Carbonaceous Carbon Black/Carbon Nanofibers for Electrochemical Sensing of Bisphenol A in Food by Jin Wang, Zhen Yang, Shuanghuan Gu, Mingfei Pan, Longhua Xu

“…The development of an efficient and sensitive sensing strategy for the monitoring of BPA residues is of paramount importance. A novel electrochemical sensor based on carbon black and carbon nanofibers composite (CB/f-CNF)-assisted signal amplification has been successfully constructed for the amperometric detection of BPA in foods. …”
Get full text

Comprehensive characterization of higher order structure changes in methionine oxidized monoclonal antibodies via NMR chemometric analysis and biophysical approaches by Mingyue Li, Victor A. Beaumont, Shahajahan Akbar, Hannah Duncan, Arch Creasy, Wenge Wang, Kelly Sackett, Lisa Marzilli, Jason C. Rouse, Hai-Young Kim

“…Furthermore, we leveraged a novel 15N-Met labeling technique of the antibody to directly observe structural perturbations at the oxidation sites. …”
Get full text

Efficacy and Safety of New Oral Anticoagulants versus Warfarin in the Resolution of Atrial Fibrillation with Left Atrial/Left Atrial Appendage Thrombus: A Systematic Review and Met... by Guan-lian Mo, Jing Wen, Yu-yu Ye, Yong-qi Lu, Tian-ming Gan, Ying-jie Yang, Jin-yi Li

“…Background: To compare the efficacy and safety of novel oral anticoagulants (NOACs) and vitamin K antagonists (VKAs) in nonvalvular atrial fibrillation (NVAF) patients with left atrial/left atrial thrombosis through a systematic review and meta-analysis. …”
Get full text

A New Geometry of Multi-band MIMO Antenna for 5G and 6G Systems by Karrar Shakir Muttair, Oras Ahmed Shareef, Hazeem Baqir Taher, Faiz Arith

“…In this manuscript, we propose a novel geometry for a 4-port multi-in multi-out (MIMO) antenna with an L-shaped structure that solves the limitations of current designs in UWB applications. …”
Get full text

FBATCNet: A Temporal Convolutional Network With Frequency Band Attention for Decoding Motor Imagery EEG by Shuaishuai Ma, Jidong Lv, Wenjie Li, Yan Liu, Ling Zou, Yakang Dai

“…In addition, compared to decoding MI-EEG signals from different limbs, decoding MI-EEG signals from same limb faces more challenges. We introduced a novel tri-class fine motor imagery (FMI) paradigm and collected electroencephalogram (EEG) data from 20 healthy subjects for decoding research. …”
Get full text

Blood-brain barrier breakdown in brain ischemia: Insights from MRI perfusion imaging by Sarvin Sasannia, Richard Leigh, Pouya B. Bastani, Hyeong-Geol Shin, Peter van Zijl, Linda Knutsson, Paul Nyquist

“…Finally, in this review, we explore the implications of the mentioned neuroimaging findings, which emphasize the potential of neuroimaging biomarkers to guide personalized treatment and inform novel neuroprotective strategies. This review highlights the importance of investigating BBB changes in brain ischemia and the critical role of advanced neuroimaging in improving patient care and advancing stroke research.…”
Get full text

Therapeutic potential of mesenchymal stem cell-derived extracellular vesicles in ischemic stroke: A meta-analysis of preclinical studies by Xiaoming Zhang, Yibing Guo, Kun Fang, Xiangqian Huang, Duo Lan, Mengqi Wang, Lina Jia, Xunming Ji, Ran Meng, Da Zhou

“…Background: Ischemic stroke (IS) remains a significant global health burden, necessitating the development of novel therapeutic strategies. This study aims to systematically evaluate the therapeutic effects of mesenchymal stem cell-derived exosomes (MSC-Exos) on IS outcomes in rodent models. …”
Get full text

A Low-Cost Electrochemical Cell Sensor Based on MWCNT-COOH/α-Fe₂O₃ for Toxicity Detection of Drinking Water Disinfection Byproducts by Ying Liu, Zhipeng Zhang, Yuling Wu, Huan Yang, Jiao Qu, Xiaolin Zhu

“…In this study, a pencil graphite electrode (PGE) was modified with carboxylated multi-walled carbon nanotubes (MWCNT-COOH) and nano-iron (III) oxide (α-Fe₂O₃) to fabricate a low-cost electrode with excellent electrocatalytic performance for cell-active substances. Subsequently, a novel cellular electrochemical sensor was constructed for the sensitive detection of the toxicity of three drinking water DBPs. …”
Get full text

Psychological Safety in Saudi Arabian Healthcare: A Scoping Review by Yumna Ali, Roaya Alqurashi, Ahmed M. Asfahani, Mark Leonard, Catherine Elisa John, Yasuhiro Kotera

“…Our aim, therefore, is to raise awareness of the potential for novel intervention programs to improve psychological safety. …”
Get full text

A forestry investigation: Exploring factors behind improved tree species classification using bark images by Gokul Kottilapurath Surendran, Deekshitha, Martin Lukac, Martin Lukac, Jozef Vybostok, Martin Mokros

“…Novel ground-based remote sensing approaches have demonstrated high potential for accurate and detailed mapping and monitoring of forest ecosystems. …”
Get full text

Innovative Fly-Ash-Based Soil Crust Rehabilitation: Enhancing Wind Erosion Resistance in Gravel-Layered Desert Mining Areas by Yu Zheng, Weiming Guan, Jingwen Li, Zhenqi Hu, Gensheng Li, Meng Xie, Xuewei Zhang

“…This study provides a novel approach to gravel layer restoration in arid mining regions using fly ash as a soil stabilizer, offering a sustainable method to enhance wind erosion resistance and promote fly ash recycling.…”
Get full text

From Disruption to Reconstruction: Implementing Peer Support in Homelessness During Times of Crisis for Health and Social Care Services by Mathieu Isabel, Daniel Turgeon, Émilie Lessard, Andreea-Cătălina Panaite, Gwenvaël Ballu, Odile-Anne Desroches, Ghislaine Rouly, Antoine Boivin

“…Moreover, the concept of crisis itself can be reexamined by clinical and research teams worldwide as potentially enabling the implementation of novel initiatives.…”
Get full text

Kinetic origin of hysteresis and the strongly enhanced reversible barocaloric effect by regulating the atomic coordination environment by Zi-Bing Yu, Hou-Bo Zhou, Feng-Xia Hu, Jian-Tao Wang, Fei-Ran Shen, Lun-Hua He, Zheng-Ying Tian, Yi-Hong Gao, Bing-Jie Wang, Yuan Lin, Yue Kan, Jing Wang, Yun-Zhong Chen, Ji-Rong Sun, Tong-Yun Zhao, Bao-Gen Shen

“…These results reveal the atomic-scale mechanism regulating hysteresis and provide insights into tailoring the functional properties of novel caloric refrigeration materials.…”
Get full text