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11761
Greenness assessment approach for spectrofluorimetric detection of daptomycin using metal oxide nanosensors synthesized via Commiphora myrrha extract in the presence of organizing...
Published 2025-01-01“…The study describes a unique analytical method for detecting daptomycin (DPT) in pharmaceutical formulations, which employs a novel fluorescent system based on zinc oxide nanoparticles (ZnO-NPs) and cetylpyridinium chloride (CPC). …”
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11762
Hydration with Mannitol and Dextrose May Promote Cisplatin-Induced Nephrotoxicity: Test of Five Protocols of Hydration during Cisplatin Therapy in Rat Models
Published 2021-01-01“…Cisplatin (CP) still is a novel choice for solid tumor therapy, but it is accompanied with the side effect of nephrotoxicity. …”
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11763
The Modulation of Meteorological Parameters on Surface PM2.5 and O3 Concentrations in Guangzhou, China
Published 2020-07-01“…These results further our understanding of the relationship between weather conditions and pollutant concentrations. Following the novel approach proposed in this study, meteorological parameters can be utilized to forecast the air quality or compare the effects of weather on pollution between different years.…”
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11764
Grand Challenges at the Interface of Engineering and Medicine
Published 2024-01-01“…Over the past two decades Biomedical Engineering has emerged as a major discipline that bridges societal needs of human health care with the development of novel technologies. Every medical institution is now equipped at varying degrees of sophistication with the ability to monitor human health in both non-invasive and invasive modes. …”
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11765
Oxidation Degradation of Rhodamine B in Aqueous by UV/S2O8 2− Treatment System
Published 2012-01-01“…The UV photolysis of persulfate (S2O8 2−) is a novel advanced oxidation technologies (AOTs), which leads to the formation of strong oxidizing radicals, sulfate radicals (SO4 •−). …”
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11766
A rapid method for the preparation of an in vitro osteoporosis model of calf vertebrae: histological and biomechanical study
Published 2025-02-01“…BackgroundIn vitro biomechanical testing is crucial for the preclinical assessment of novel implant designs. Given the constraints of limited supply and high costs associated with human specimens, calf spines are frequently employed as surrogates for human spines in both in vivo and in vitro biomechanical studies.MethodsThis study selected 60 spinal vertebrae from calves aged between 12 and 18 weeks. …”
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11767
Spinal Cord Stimulation for Refractory Angina Pectoris: Current Status and Future Perspectives, a Narrative Review
Published 2025-01-01“…Proposed mechanisms include modulation of pain signals via the gate control theory, enhancement of autonomic balance, and redistribution of myocardial perfusion. Novel stimulation modalities, including high-frequency, Burst, and Differential Target Multiplexed (DTM), show potential advantages in enhancing patient comfort and clinical outcomes. …”
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11768
Deterministic genetic barcoding for multiplexed behavioral and single-cell transcriptomic studies
Published 2025-02-01“…Advances in single-cell sequencing technologies have provided novel insights into the dynamics of gene expression and cellular heterogeneity within tissues and have enabled the construction of transcriptomic cell atlases. …”
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11769
The Roles of PI3K/AKT/mTOR and MAPK/ERK Signaling Pathways in Human Pheochromocytomas
Published 2016-01-01“…Inhibiting multiple pathways might be a novel therapeutic approach for PPGLs.…”
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11770
Retrotrans-genomics identifies aberrant THE1B endogenous retrovirus fusion transcripts in the pathogenesis of sarcoidosis
Published 2025-02-01“…Single-cell or single-nucleus RNA-seq analyses of sarcoidosis not only confirmed these transcripts but also revealed a novel read-through transcript, SIRPB1-SIRPD, and TREM2.1, predominantly in granuloma-associated macrophages. …”
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11771
Individual Differences in Behavioural Despair Predict Brain GSK-3beta Expression in Mice: The Power of a Modified Swim Test
Published 2016-01-01“…While deficient brain plasticity is a well-established pathophysiologic feature of depression, little is known about disorder-associated enhanced cognitive processing. Here, we studied a novel mouse paradigm that potentially models augmented learning of adverse memories during development of a depressive-like state. …”
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11772
Effect of interface morphology on tensile response of Ti6Al4V alloy fabricated by laser hybrid additive manufacturing: Experiments & simulations
Published 2025-03-01“…The model incorporates anisotropic properties of the DED part and accounts for multi-scale microstructural variations across regions. A novel numerical simulation approach is employed to capture the transitional properties of the interface, which are often simplified in traditional models. …”
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11773
Production of prototype lab-scale oak barrel analogues using additive manufacturing
Published 2025-01-01“…This preliminary research study investigated a novel use of additive manufacturing (3D printing) to fabricate cost-effective laboratory-scale maturation vessels that required less volume to fill but still achieved a surface-area-to-volume ratio of oak contact closer to that of a conventionally sized barrel. …”
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11774
Kinetic and isotherm studies of nickel and cadmium ions adsorption onto Clay-Chitosan composite
Published 2025-01-01“…They contaminate ecosystem, endangering the survival of many species, including humans. In this study, a novel clay-chitosan composite was prepared and characterized to evaluate its adsorption potential for the removal of these pollutants. …”
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11775
The effect of self-compassion versus mindfulness interventions on autonomic responses to stress in generalized anxiety disorders
Published 2025-02-01“…We also demonstrated a significant correlation between decreased heart rate response and less negative emotions.ConclusionThe Findings provides novel physiological evidence that self-compassion interventions buffer stress reactivity in individuals with GAD. …”
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11776
CDR-Detector: a chronic disease risk prediction model combining pre-training with deep reinforcement learning
Published 2024-12-01“…Aiming at this challenge, this study combines EHR based pre-training and deep reinforcement learning to develop a novel chronic disease risk prediction model called CDR-Detector. …”
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11777
Hydrothermal performance of microchannel heat sink integrating pin fins based on triply periodic minimal surfaces
Published 2025-02-01“…The results show that the novel hybrid designs, which combine both square pin fins and the I-graph wrapped package-graph (IWP) lattice at their core, achieve a 54% reduction in pressure drop without compromising thermal performance, as indicated by average Nusselt numbers and maximum temperatures, compared to conventional square pins. …”
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11778
Sensor Image, Anomaly Detection Method for Hydroelectric Dam Structure Using Sensors Measurements and Deep Learning
Published 2025-01-01“…Thus, the sensor measurement input vector for machine learning algorithms should be a multidimensional vector instead of a one-dimensional vector, as suggested by the traditional tabular form of data. In this study, a novel method for addressing these problems is proposed. …”
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11779
Genetic and peripheral biomarkers of comorbid posttraumatic stress disorder and traumatic brain injury: a systematic review
Published 2025-01-01“…Additional research is needed to determine how such factors indicate, predict, and contribute to comorbidity and to what extent they represent viable targets for the development of novel diagnostic tools and therapeutic interventions.…”
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11780
Frequency Spectrum-Based Optimal Texture Window Size Selection for High Spatial Resolution Remote Sensing Image Analysis
Published 2019-01-01“…Other than scale selection in spatial domain, this paper casts a novel idea for texture scale selection in the frequency domain, which is meant for scale processing of remote sensing image.…”
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