Revisiting the Link Between HLA‐DRB1 Alleles and Autoantibodies in Rheumatoid Arthritis: Association of non‐Shared Epitope Alleles *09 and *15 With High Levels of Anti–Citrullinate... by Denis Lagutkin, Luis Panaifo, Ahmad‐Fauzi Nurul‐Aain, Lena Israelsson, Monika Hansson, Karin Lundberg, Lars Alfredsson, Johan Askling, RACI consortium, Lars Klareskog, Chun‐Lai Too, Leonid Padyukov

“…Results Our data show that non‐shared epitope alleles HLA‐DRB1*09 and *15 exhibit significant associations with ACPA levels. Notably, these novel associations were independent of ethnicity. …”
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Magnetic Colloidal Particles in Combinatorial Thin-Film Gradients for Magnetic Resonance Imaging and Hyperthermia by Sumera Khizar, Nasir Mahmood Ahmad, Hassan Saleem, Muhammad Asif Hamayun, Sadia Manzoor, Noureddine Lebaz, Abdelhamid Elaissari

“…The research work described here is novel and elaborates the fabrication of thin-film gradients with 5, 10, 15, and 20 bilayers by layer-by-layer technique using polydimethyl diallyl ammonium chloride (PDAC) and prepared magnetic colloidal particles. …”
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Open-Label Fosmetpantotenate, a Phosphopantothenate Replacement Therapy in a Single Patient with Atypical PKAN by Yiolanda-Panayiota Christou, George A. Tanteles, Elena Kkolou, Annita Ormiston, Kostas Konstantopoulos, Maria Beconi, Randall D. Marshall, Horacio Plotkin, Kleopas A. Kleopa

“…We describe the treatment of the first, later-onset PKAN patient with oral fosmetpantotenate (previously known as RE-024), a novel replacement therapy developed to bypass the enzymatic defect. …”
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Neurological function is restored post-ischemic stroke in zebrafish, with aging exerting a deleterious effect on its pathology by Takamasa Mizoguchi, Ayumi Maki, Yuno Nakase, Mayu Okita, Yuina Minami, Misa Fukunaga, Motoyuki Itoh

“…Collectively, our analysis of the zebrafish IS model and its comparison with existing rodent models may lay the groundwork for novel IS treatment strategies. Furthermore, the zebrafish IS model may prove beneficial for analyzing the impact of aging on the pathology of IS and the recovery process.…”
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Comparative Investigation of Vortex and Direct Plasma Discharge for Treating Titanium Surface by Hyun-Jeong Jeon, Subin Seo, Ara Jung, Kyeong-mok Kang, Jeonghoon Lee, Bomi Gweon, Youbong Lim

“…To address this challenge, we developed a novel plasma source, termed “vortex plasma”, which generates uniform plasma using a magnetic field within a controlled space. …”
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Future changes in compound explosive cyclones and atmospheric rivers in the North Atlantic by F. Lopez-Marti, F. Lopez-Marti, M. Ginesta, D. Faranda, A. Rutgersson, A. Rutgersson, P. Yiou, L. Wu, G. Messori, G. Messori, G. Messori

“…As such, our work provides a novel statistical relation between explosive cyclones and atmospheric rivers in CMIP6 climate projections and a characterization of their joint changes in intensity and location.…”
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Work-Domain Goal Orientation: A Theoretical Framework for the Construct and Turkish Adaptation of a Work-Domain Goal Orientation Instrument by Aysun Gurol, Dilek Ilhan Findikoglu, Mehmet Gurol, Fuat Findikoglu, Mehmet Yesilkaya

“…This study brings a novel perspective to the relationship between higher education and work life by examining work-domain goal orientation as a critical factor in preparing students for professional environments. …”
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Additive manufacturing of Fe-6.5Si cores with metal-insulator-metal structure via dual-nozzle material extrusion (MEX) technology by Taehyeob Im, Suyeon Kim, Juyong Kim, Minjong Kim, Jonghyeok Ahn, Kwiyoung Lee, Dongju Lee, Jai-Sung Lee, Jongryoul Kim, Caroline Sunyong Lee

“…This study proposes a novel approach for fabricating Fe-6.5 wt. %Si (Fe-6.5Si) soft magnetic cores using a dual-nozzle material extrusion (MEX) three-dimensional (3D) printing technology followed by a spark plasma sintering (SPS) process. …”
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Long-term copper exposure induced pyroptosis and inflammation of rat spleen through intestinal-splenic axis by Jinwen Quan, Xiaoyue Chang, Siying Liu, Ting He, Gaolong Zhong, Zhonghua Liu, Wenlan Yu

“…These findings offer a novel perspective on how copper may induce spleen injury through the intestine-spleen axis.…”
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CC16 alleviates PM2.5-induced lung epithelial cell injury and airway inflammation in asthmatic mice by inhibiting ferroptosis by Aili Wang, Jianling Liu, Zhangwen Li, Ze Qian, Shuo Yang, Shaohua Luo, Jinle Lin, Jian Wu

“…Conclusion: CC16 demonstrates promise as a therapeutic agent for PM2.5-induced asthma by modulating ferroptosis and alleviating airway inflammation, thereby providing a novel strategy for asthma management.…”
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Evaluation of allergenic protein profiles in three Chinese high-oleic acid peanut cultivars using NanoLC-Orbitrap mass spectrometry by Xinke Yang, Haochen Bai, Lijun Yin, Jin Wang, Wentong Xue, Xin Jia

“…Through the peptide-filtering pipeline, three novel peptide markers, IVQIEAKPNTLVLPK, SSNPDIYNPQAGSLR and AQSENYEYLAFK surrogate to Ara h 1, Ara h 3 with high abundance, good MS response and highly reliability were identified, which can be used as candidate peptide markers for the detection of peanut allergens in different food matrices.…”
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Synergistic effects of PS-NPs and Cd on ovarian toxicity in adolescent rats: Ferroptosis by induction of mitochondrial redox imbalance via the SIRT3-SOD2/Gpx4 pathway by Hua Wu, Lihua Feng, Huang Wu, Lihong Wang, Hengyi Xu, Fen Fu

“…Our results suggested that co-exposure to PS-NPs and Cd may trigger ferroptosis by inhibiting the SIRT3-SOD2/Gpx4 pathway, leading to mitochondrial redox imbalance, which provided novel insights into reproductive toxicity due to the interaction of PS-NPs and Cd during adolescence.…”
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Triplet Electron Exchange in Carbon Nanodots‐assisted Long‐persistent near‐infrared Chemiluminescence for Oncology Synergistic Imaging and Therapy by Run‐Wei Song, Tian‐Ci Jiang, Xue‐Yang Zhang, Cheng‐Long Shen, Qing Lou, Chong‐Xin Shan

“…As a proof‐of‐concept, the photosensitizers of carbon nanodots (CDs)‐loaded chlorin e6 (CDs‐Ce6) are designed and integrated with the peroxalate molecules, and the as‐prepare polymer carbon nanodots (p‐CDs) exhibit novel tumor microenvironment (TME)‐responsive long‐persistent near‐infrared CL and photochemical reactions, evoking the in vivo imaging and synergistic dynamic therapy in tumor tissue. …”
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Knockdown of Fibromodulin Inhibits Proliferation and Migration of RPE Cell via the VEGFR2-AKT Pathway by He Hu, Shanshan Li, Jianqiao Li, Chao Huang, Fang Zhou, Li Zhao, Wenzhen Yu, Xiao Qin

“…Recent research has provided novel insight into the function of fibromodulin (FMOD) in wound healing and angiogenesis. …”
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Optimizing Non-Thermal Magnetic Field to Minimize Weight Loss and Tissue Degradation: Identifying Possible Enzyme Inhibition Mechanisms by Chao-Kai Chang, Prakoso Adi, Rizka Mulyani, Chun-Fu Lin, Ratna Sari Listyaningrum, Shella Permatasari Santoso, Mohsen Gavahian, Chang-Wei Hsieh

“…This research investigates potential mechanisms of novel magnetic field (MF) treatments in inhibiting cell-wall-degrading enzymes, aiming to reduce weight loss and preserve the post-harvest quality of tomatoes (<i>Solanum lycopersicum</i> L.) as a climacteric fruit. …”
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Wedge‐Like Microstructure of Al2O3/i‐Ti3C2Tx Electrode with “Nano‐Pumping” Effect for Boosting Ion Diffusion and Electrochemical Defluoridation by Junce Wang, Jinfeng Chen, Ningning Liu, Jingjing Lei, Hong‐Wen Gao, Fei Yu, Fanghui Pan, Jie Ma

“…The physicochemical coupling strategy opens a novel approach to optimizing the interlayer structure and in situ modification interface of MXene, which also provids a universal idea for efficient capture of varisized ions of intercalation materials.…”
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Immune Dysfunction in Rett Syndrome Patients Revealed by High Levels of Serum Anti-N(Glc) IgM Antibody Fraction by Anna Maria Papini, Francesca Nuti, Feliciana Real-Fernandez, Giada Rossi, Caterina Tiberi, Giuseppina Sabatino, Shashank Pandey, Silvia Leoncini, Cinzia Signorini, Alessandra Pecorelli, Roberto Guerranti, Solange Lavielle, Lucia Ciccoli, Paolo Rovero, Claudio De Felice, Joussef Hayek

“…To determine immunoglobulins we used both a conventional agglutination assay and a novel ELISA based on antibody recognition by a surrogate antigen probe, CSF114(Glc), a synthetic N-glucosylated peptide. …”
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Mesalazine solubility in supercritical carbon dioxide with and without cosolvent and modeling by Seyed Ali Sajadian, Nadia Esfandiari, Adrián Rojas, Salar Hemmati, Abolghasem Jouyban, Gonzalo Aguila, Chandrasekhar Garlapati

“…Meanwhile, the determined experimental molar solubilities in supercritical carbon dioxide using 2% dimethyl sulfoxide as cosolvent were in the range of 28.22 × 10–5 to 36.2 × 10–5 (308 K), 26.07 × 10–5 to 51.41 × 10–5 (318 K), 25.02 × 10–5 to 69.07 × 10–5 (328 K) and 25.86 × 10–5 to 82.6 × 10–5 (338 K). A novel association model was employed to simulate the solubility data of the binary and ternary systems. …”
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A Reduction in Selenoprotein S Amplifies the Inflammatory Profile of Fast-Twitch Skeletal Muscle in the mdx Dystrophic Mouse by Craig Robert Wright, Giselle Larissa Allsopp, Alex Bernard Addinsall, Natasha Lee McRae, Sofianos Andrikopoulos, Nicole Stupka

“…There is interest in characterising novel genes that regulate inflammation due to their potential to modify disease progression. …”
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Identification of QTLs for resistance to leaf and stem rusts in bread wheat (Triticum aestivum L.) using a mapping population of ‘Pamyati Azieva × Paragon’ by Y. Genievskaya, Y. Fedorenko, A. Sarbayev, A. Amalova, S. Abugalieva, S. Griffiths, Y. Turuspekov

“…Two QTLs for LR resistance and eight for SR resistance were found in the north, and the genetic positions of eight of them have matched the positions of the known Lr and Sr genes, while two QTLs for SR were novel. In the southeast, eight QTLs for LR and one for SR were identified in total. …”
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