Ventral hippocampus to nucleus accumbens shell circuit regulates approach decisions during motivational conflict. by Dylan Patterson, Nisma Khan, Emily A Collins, Norman R Stewart, Kian Sassaninejad, Dylan Yeates, Andy C H Lee, Rutsuko Ito

“…Chemogenetic inhibition of the vCA1-NAc shell circuit resulted in animals exhibiting increased decision-making time and avoidance bias specifically in the face of motivational conflict, as the same behavioral phenotype was absent in separate conditioned cue preference and avoidance tests. vCA1-NAc shell inhibition also led to a reduction in seeking social interaction with a novel rat but did not alter anxiety-like behaviors. …”
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Unveiling the omics tapestry of B-acute lymphoblastic leukemia: bridging genomics, metabolomics, and immunomics by Yin Le, Shicong Zhu, Hongling Peng, Zhihua Wang

“…Based on these findings, this study provides novel potential therapeutic targets for the personalized treatment of B-ALL and lays the foundation for further development of PI3K-Akt pathway inhibitors and immunometabolism-targeted therapies.…”
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Model Selection from Multiple Model Families in Species Distribution Modeling Using Minimum Message Length by Zihao Wen, David L. Dowe

“…To find the relevant features efficiently, we further develop a novel search algorithm that does not require calculating the message length for all possible subsets of features. …”
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"Theory of Pore Conflation" and "Shubhjyot's equation" in the treatment of Brilliant green dye-contaminated water using Jamun leaves biochar by Shubham Sutar, Jyoti Jadhav

“…It was found that the adsorption process adhered to the Freundlich isotherm model and pseudo-second-order kinetics, revealing heterogeneous adsorption with chemisorption. A novel "Theory of Pore Conflation" was proposed to explain enhanced adsorption at higher temperatures, supported by SEM and FTIR analyses. …”
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The Impact of Pore Structure on Kerogen Geomechanics by Saad Alafnan

“…The results signify the impact of kerogen’s microscale intricacies on its mechanical properties and hence on the shale matrix. This work provides a novel methodology for constructing kerogen structures with different microscale properties that will be useful for delineating fundamental characteristics such as mechanical properties. …”
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5-Aminolevulinic acid activates the MdWRKY71-MdMADS1 module to enhance anthocyanin biosynthesis in apple by Liuzi Zhang, Huihui Tao, Jianting Zhang, Yuyan An, Liangju Wang

“…Then, we identified a novel WRKY transcription factor, MdWRKY71, that interacts with MdMADS1. …”
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Breast cancer classification based on hybrid CNN with LSTM model by Mourad Kaddes, Yasser M. Ayid, Ahmed M. Elshewey, Yasser Fouad

“…This paper presents a novel hybrid model of DL models combined a Convolutional Neural Network (CNN) and Long Short-Term Memory (LSTM) for binary breast cancer classification on two datasets available at the Kaggle repository. …”
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Asporin Reduces Adult Aortic Valve Interstitial Cell Mineralization Induced by Osteogenic Media and Wnt Signaling Manipulation In Vitro by Anisha Polley, Riffat Khanam, Arunima Sengupta, Santanu Chakraborty

“…Overall, all these data are highly indicative that Asporin might be a novel biomolecular target to treat patients of calcific aortic valve disease over current cusp replacement surgery.…”
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Isolation and Characterization of Multipotent Turkey Tendon-Derived Stem Cells by Qian Liu, Yaxi Zhu, Peter C. Amadio, Steven L. Moran, Anne Gingery, Chunfeng Zhao

“…The successful isolation of tendon-derived stem cells from turkey was beneficial for future studies in tendon tissue engineering and would help in the development of new treatment for tendon diseases using this novel animal model.…”
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Proteome-wide mendelian randomization identifies causal plasma proteins in interstitial lung disease by Kunrong Yu, Wanying Li, Wenjie Long, Yijia Li, Yanting Li, Huili Liao, Jianhong Liu

“…Based on these findings, we propose for the first time that CDH15, ADAM15, and LTBR hold promise as novel potential circulating protein biomarkers and therapeutic targets for the diagnosis and treatment of ILD, IPF, and sarcoidosis, respectively, especially ADAM15, and these findings have the potential to provide new perspectives for advancing the research on the heterogeneity of ILD.…”
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Decoding Subjective Understanding: Using Biometric Signals to Classify Phases of Understanding by Milan Lazic, Earl Woodruff, Jenny Jun

“…Further, they advance a novel approach for measuring and fostering understanding in educational settings, as well as developing adaptive learning technologies and personalized educational interventions. …”
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Deep-insights: Nanoengineered gel-based localized drug delivery for arthritis management by Anitha Sriram, Harshada Ithape, Pankaj Kumar Singh

“…This review emphasizes deep insights into drug delivery using diverse gel-based novel nanocarriers, exploring their various applications embedded in hyaluronic acid (biopolymer)–based gels, carbopol-based gels, and others. …”
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On supergravity and noncritical strings by Andrea Dei, Pietro Ferrero, Leonardo Rastelli

“…In particular, we find a novel class of solutions with RR flux, parametrized by a function of three variables that solves an elegant PDE. …”
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Deconstructing the Politics of Linguistic Mutation in Tom Stoppard’s Dogg’s Hamlet, Cahoot’s Macbeth by Sarra Jouini

“…Stoppard’s innovative linguistic experimentation transforms Shakespeare’s plays, Hamlet and Macbeth, into an entirely novel linguistic system, named “Doggspeak,” which derives inspiration from Ludwig Wittgenstein’s Philosophical Investigations. …”
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Dependence of Climate and Carbon Cycle Response in Net Zero Emission Pathways on the Magnitude and Duration of Positive and Negative Emission Pulses by K. U. Jayakrishnan, Govindasamy Bala, Ken Caldeira

“…In this study, using a coupled climate and carbon cycle model, a novel set of nine stylized simulations are conducted with cumulative emissions of 1,000 GtC, 2,000 GtC, and 5,000 GtC over 150, 250, and 500 years, followed by identical cumulative negative emissions so that the net cumulative emissions are zero. …”
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In Situ Curing of a Polymer Film for Light-Proof Coring of Deep Rocks with Preservation of Rock Quality and Moisture by Zhiyu Zhao, Heping Xie, Tao Liu, Yifan Wu

“…In this study, we developed a novel in situ quality-preserving coring method of deep rocks based on an in situ film-forming process. …”
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Reliable Quantized Fuzzy Controller Design for Nonlinear Singularly Perturbed Systems With Markovian Jumps and Dynamic Event Triggered Mechanism by Rabeh Abbassi, Mourad Kchaou, Hamdi Gassara, Houssem Jerbi

“…This paper proposes a novel approach to handling random actuator failures in control systems through robust and reliable control techniques. …”
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Bringing Intelligence to SAR Missions: A Comprehensive Dataset and Evaluation of YOLO for Human Detection in TIR Images by Mostafa Rizk, Israa Bayad

“…To support the investigation, a novel dataset comprising 17,148 thermal images with 90,882 instances of human subjects representing various conditions and scenarios has been carefully curated. …”
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Collaborative Optimization of Container Liner Slot Allocation and Empty Container Repositioning Within Port Clusters by Wenmin Wang, Cuijie Diao, Wenqing He, Zhihong Jin, Zaili Yang

“…A cooperative possession strategy and a hybrid (T, s) inventory control policy are incorporated in this paper. A novel mixed-integer programming model is proposed, enabling us to simultaneously track slot allocation, empty container repositioning, empty container leasing, and slot renting. …”
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Vibration and Sound Transmission Performance of Sandwich Panels with Uniform and Gradient Auxetic Double Arrowhead Honeycomb Cores by Qing Li, Deqing Yang

“…Auxetic mechanical metamaterials that exhibit a negative Poisson’s ratio (NPR) can be artificially designed to exhibit a unique range of physical and mechanical properties. Novel sandwich structures composed of uniform and gradient auxetic double arrowhead honeycomb (DAH) cores were investigated in terms of their vibration and sound transmission performance stimulated by nonhomogeneous metamaterials with nonperiodic cell geometries. …”
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