Dynamic Amplification Factor of Shear Force on Bridge Columns under Impact Load by Haiying Ma, Zhen Cao, Xuefei Shi, Junyong Zhou

“…However, SDOF method neglects the effect of the higher-order modes, leading to big difference between the calculated results and the real induced forces. Therefore, a novel method to obtain dynamic response under concentrated impact load including the effect of higher-order modes is proposed in the paper, which is based on the modified Timoshenko beam theory (MTB) and the classical Timoshenko beam theory (CTB). …”
Get full text

A Golgi apparatus‑related subtype and risk signature predicts prognosis and evaluates immunotherapy response in gastric cancer by Ruyue Chen, Zengwu Yao, Lixin Jiang, Jinchen Hu

“…Abstract Background Gastric cancer (GC) remains a significant health burden, calling for the discovery of novel biomarkers. Golgi apparatus, a crucial cellular organelle involved in tumorigenesis, remains underexplored in GC research. …”
Get full text

CTSK and PLAU as Prognostic Biomarker and Related to Immune Infiltration in Pancreatic Cancer: Evidence from Bioinformatics Analysis and qPCR by Yuntao Ding, Zhangzuo Li, Huizhi Wang, Qi Wang, Han Jiang, Zhengyue Yu, Min Xu

“…There is a pressing need for novel biomarkers that can facilitate early detection and serve as targets for therapeutic interventions beyond the commonly utilized CA199 marker. …”
Get full text

Computer-aided cholelithiasis diagnosis using explainable convolutional neural network by Dheeraj Kumar, Mayuri A. Mehta, Ketan Kotecha, Ambarish Kulkarni

“…Although several computer-aided cholelithiasis diagnosis approaches have been introduced in the literature, their use is limited because Convolutional Neural Network (CNN) models are black box in nature. Therefore, a novel approach for cholelithiasis classification using custom CNN with post-hoc model explanation is proposed. …”
Get full text

A new discrete GaN-based dv/dt control circuit for megahertz frequency power converters by Bright K. Banzie, John K. Annan, Francis B. Effah

“…In this paper, we present a novel GaN-based discrete current mirror active gate driver (AGD) for closed-loop dv/dt control, designed specifically for megahertz (MHz) frequency power converters employing power devices with low reverse transfer capacitance (CRSS) values. …”
Get full text

V's Virtual Afterlife by Jasmyn Connell, Christopher Moore, Reneé Middlemost

“…We propose ‘persona analysis’ as a novel qualitative case study methodology for researching NHOPs. …”
Get full text

Synthetic data as external control arms in scarce single-arm clinical trials. by Severin Elvatun, Daan Knoors, Simon Brant, Christian Jonasson, Jan F Nygård

“…However, accessing such observational healthcare data involves a lengthy and intricate application process, delaying drug approval studies and access to novel treatments. Clinical trials typically comprise only a few hundred patients usually with high-cardinality features, which makes individual data instances more exposed to re-identification attacks. …”
Get full text

A new method of distracting attention: Is it effective for pain and fear during phlebotomy in children? by Mine Aydemir Sahin, Yeliz Cigerci, Hamide Nur Cevik Ozdemir

“…This study examined the impact of a novel distraction approach on the mitigation of fear and pain experienced by children between the ages of 7 and 12 during phlebotomy procedures. …”
Get full text

Photocatalytic Degradation of Gaseous Acetone by Photocatalysts with Visible Light and their Potential Applications in Painting by Yu-Hua Li, Sheng-Hua Yang, Chung-Shin Yuan, Huazhen Shen, Chung-Hsuang Hung

“…Therefore, this investigation aimed to produce a novel visible induced photocatalyst component in paint. …”
Get full text

A Study of Serum Adiponectin Levels in Patients with Polycystic Ovarian Syndrome and its Correlation with Various Cardiometabolic Risk Markers by G. Surendra Prasad, Uma Kaimal Saikia, Ashok Krishna Bhuyan, Abhamoni Baro

“…Background: Polycystic ovarian syndrome (PCOS) is the most common metabolic disorder in the reproductive age group, the pathogenesis of which is constantly evolving with the discovery of novel molecules and the lookout for potential therapeutic targets. …”
Get full text

The Use of Noninvasive Velacur® for Discriminating between Volunteers and Patients with Chronic Liver Disease: A Feasibility Study by Michael P. Curry, Edward Tam, Caitlin Schneider, Noha Abdelgelil, Tarek Hassanien, Nezam H. Afdhal

“…We evaluated the feasibility of a novel shear wave absolute vibroelastography (S-WAVE) modality called Velacur® for assessing liver stiffness measurement (LSM) for fibrosis and attenuation coefficient estimation (ACE) in differentiating patients with chronic liver disease from normal healthy controls. …”
Get full text

A New Density Model of Quartz Solubility in H2O-CO2-NaCl Ternary Systems up to High Temperatures and High Pressures by Weiping Deng, Qing Wei, Xuan Liu

“…A novel density model for computing quartz solubility in H2O-CO2-NaCl hydrothermal fluids applicable to wide ranges of temperature and pressure is proposed. …”
Get full text

IC-GraF: An Improved Clustering with Graph-Embedding-Based Features for Software Defect Prediction by Xuanye Wang, Lu Lu, Qingyan Tian, Haishan Lin

“…Therefore, we introduce a novel framework called improved clustering with graph-embedding-based features (IC-GraF) for SDP without the reliance on historical data. …”
Get full text

Copula-Based Method for Estimating the Minimum Void Ratio Parameters of Tailings Deposits by Hao Li, Yichuan Tang, Shibo Li, Jianquan Ma, Xiaojie Zhao

“…The method proposed in this paper uses the existing measured data to establish a joint probability distribution model and combines the collected fine particle content and specific gravity data with the guarantee rate to estimate the minimum void ratio, providing a novel basis for the study of the physical properties of tailings.…”
Get full text

EMG-Based Continuous Estimation of Index Finger Movements With Varying Interjoint Coordination Patterns by Modeling Musculoskeletal Dynamics by Trenton A. Gilstrap, Mada M. Alghamdi, Thanh Phan, Sang Wook Lee

“…The goal of this study is to develop a novel EMG-based approach that models impact of finger intersegmental dynamics to reproduce ‘physiologic’ characteristics of coordinated finger movements. …”
Get full text

Narcolepsy treatment: from exorcism and bloodletting to modern therapy with histamine receptor inverse agonists by E. Sakalauskaitė-Juodeikienė, R. Masaitienė

“…In this article, we also review future perspectives for narcolepsy treatment including novel versions of sodium oxybate, the noradrenaline reuptake inhibitor reboxetine, the combination of modafinil and the astroglial connexins inhibitor flecainide, selective hypocretin-2 receptor agonists, and immune-based therapies. …”
Get full text

TNF-α Autocrine Feedback Loops in Human Monocytes: The Pro- and Anti-Inflammatory Roles of the TNF-α Receptors Support the Concept of Selective TNFR1 Blockade In Vivo by Jennie M. Gane, Robert A. Stockley, Elizabeth Sapey

“…TNFR1 blockade did not change the cell surface expression of TNFR2, leaving this receptor free to upregulate IL-10. These novel results support the concept of selective TNFR1 blockade in vivo in order that positive anti-inflammatory effects of TNF-α can be retained via TNFR2 ligation.…”
Get full text

Detecting travel modes from smartphone-based travel surveys with continuous hidden Markov models by Guangnian Xiao, Qin Cheng, Chunqin Zhang

“…However, these studies have struggled with three limitations: data collection-, feature selection-, and classification approach–related issues. Thus, we propose a novel framework to collect trajectory data and infer travel modes by making a great deal of effort. …”
Get full text

Strategic portfolio rebalancing: Integrating predictive models and adaptive optimization objectives in a dynamic market by Adeline Clarissa, Deddy Priatmodjo Koesrindartoto

“…This study proposes a novel portfolio management strategy using appropriate optimization objectives for different stock market trends while also incorporating market trends and stock return predictions The optimization objectives that will be evaluated for different market trends are maximizing the Sharpe ratio, minimizing risk, and minimizing expected shortfall. …”
Get full text

Fermatean Cubic Fuzzy Aggregation Operators and Their Application in Multiattribute Decision-Making Problems by Muhammad Riaz, Aurang Zeb, Fawad Ali, Muhammad Naeem, Sama Arjika

“…The key features of this work are the aggregation operators, because they are based on a novel set called Fermatean cubic fuzzy set (F-CFS). …”
Get full text