Dual Control of Host Actin Polymerization by a Legionella Effector Pair by M. Pillon, C. Michard, N. Baïlo, J. Bougnon, K. Picq, O. Dubois, C. Andrea, L. Attaiech, V. Daubin, S. Jarraud, E. Kay, P. Doublet

“…More importantly, we observed the restoration of the ΔlegK2 mutant defects, upon deletion of vipA gene, making LegK2/VipA a novel example of effector-effector suppression pair that targets the actin cytoskeleton and whose functional interaction impacts L. pneumophila virulence. …”
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Evolutionary game model for the behavior of private sectors in elderly healthcare public–private partnership under the condition of information asymmetry by Xianghua Yue, Shahzad Khan Durrani, Runfa Li, Wenling Liu, Shahid Manzoor, Muhammad Khalid Anser

“…The study examines the influence of information asymmetry, particularly on "experience" and "credence," crucial for governance and service quality in elderly healthcare PPPs in China. By developing the novel methodology of evolutionary game theory and employing MATLAB simulations, this study analyzes private sector behavior under two distinct regulatory models. …”
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Stochastic Diffusive Modeling of CO₂ Emissions with Population and Energy Dynamics by Muhammad Shoaib Arif, Kamaleldin Abodayeh, Hisham M. Al-Khawar, Yasir Nawaz

“…The objectives are to enhance the predictive accuracy of existing models by incorporating diffusion effects and stochastic variability, offering insights for sustainable environmental policies. A novel numerical scheme, an extension of the Euler-Maruyama algorithm, is proposed to solve stochastic time-dependent partial differential equations governing the model. …”
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Enhancing Deepfake Detection Through Quantum Transfer Learning and Class-Attention Vision Transformer Architecture by Bekir Eray Katı, Ecir Uğur Küçüksille, Güncel Sarıman

“…In addition to existing preprocessing methods in the literature, a novel preprocessing function tailored to the requirements of deep learning models was developed for the dataset. …”
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Conceptualizing innovation capabilities: A contingency perspective by Tor Helge Aas, Karl Joachim Breunig

“…We discuss the types of innovation capabilities necessary within the four different contexts. This novel framework contributes to the understanding of the strategy-innovation link as well as clarifies the conceptual understanding of capabilities within the strategy literature and establishes the relationship between these structures and innovation management theory.…”
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Dual Generative Network with Discriminative Information for Generalized Zero-Shot Learning by Tingting Xu, Ye Zhao, Xueliang Liu

“…To solve the above problems, we propose a novel model that uses the discriminative information of visual features to optimize the generative module, in which the generative module is a dual generation network framework composed of conditional VAE and improved WGAN. …”
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Forskolin Stimulates Estrogen Receptor (ER) α Transcriptional Activity and Protects ER from Degradation by Distinct Mechanisms by Houng-Wei Tsai, Vicky Y. Lin, Margaret A. Shupnik

“…Our results indicate distinct and novel mechanisms for forskolin stimulation of ERα transcriptional activity and protection from ligand-induced degradation. …”
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Elimination of the Impact Produced by DG Units on the Voltage Profile of Distribution Networks by Saad Ouali, Abdeljabbar Cherkaoui

“…In literature, voltage deterioration introduced by DGs has been reported as one of the main obstacles for the interconnection of large amounts of DG units to the existing networks. In this paper, the novel control strategy is based on a sensitivity formula developed to calculate the compensation needed for additional distributed flexible AC transmission system (D-FACTS) devices to push and pull the exact reactive power and to eliminate the impact produced by DGs on the network voltage profile. …”
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A Framework for Resilient Community Microgrids: Review of Operational Strategies and Performance Metrics by Joy Dalmacio Billanes, Bo Nørregaard Jørgensen, Zheng Ma

“…It also highlights performance indicators, including reliability, stability, and flexibility, that serve as benchmarks for resilience. A novel framework is proposed, integrating microgrid design and operational aspects into a cohesive model for resilience enhancement. …”
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Hyperhomocysteinemia-induced VCID results in visual deficits, reduced neuroinflammation and vascular alterations in the retina by Erica M. Weekman, Colin B. Rogers, Tiffany L. Sudduth, Donna M. Wilcock

“…These changes provide novel insights and reproduce some prior observations. …”
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Application of Response Surface Methodology (RSM) for Simultaneous Optimization of Kinetic Parameters Affecting Gold Leaching in Thiosulfate Based Media: A Statistical Approach by Nomsa P. Baloyi, Joseph M. Nseke, Mamookho E. Makhatha

“…Moreover, with global economic factors causing a decline in gold prices, it is crucial that novel hydrometallurgical methods of extracting gold minimise operational costs by using low-priced reagents such as thiosulfate. …”
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Predicting the shield effectiveness of carbon fiber reinforced mortars utilizing metaheuristic algorithms by Mana Alyami, Irfan Ullah, Furqan Ahmad, Hisham Alabduljabbar

“…Machine learning (ML) models present a faster, cost-effective alternative for simulating outcomes and exploring various scenarios. This study adopts a novel approach by utilizing hybrid models, which offer greater accuracy than individual or ensemble ML models. …”
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Multimodal approach to public health interventions using EGG and mobile health technologies by Xiao Zhang, Han Liu, Mingyang Sun, Shuangyi Feng

“…While recent advancements like Contrastive Language-lmage Pre-training(CLIP) models excel in cross-modal understanding, their application to EEG-based tasks remains limited due to the unique characteristics of EEG data.MethodsIn response, we introduce PH-CLIP (Public Health Contrastive Language-lmage Pretraining), a novel framework that combines CLIP's representational power with a multi-scale fusion mechanism designed specifically for EEG data within mobile health technologies. …”
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Natural Cyclic Peptides: Synthetic Strategies and Biomedical Applications by Devan Buchanan, Shogo Mori, Ahmed Chadli, Siva S. Panda

“…Emerging trends, including integrating computational tools for rational design, novel cyclization techniques to improve pharmacokinetic profiles, and interdisciplinary collaboration among chemists, biologists, and computational scientists, promise to expand the scope of cyclic peptide-based therapeutics. …”
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Sandwiched Strut Allografts with Stem Retention to Treat Fragile Periprosthetic Femoral Fractures: A Case Report by Hyoung Tae Kim, Hyun Jun Lee, Suenghwan Jo

“…Revision with a long stem is commonly considered but may fail to provide adequate fixation and stability in fragile bones. A novel approach using sandwiched strut allografts and controlled bone crushing with robust cable fixation can offer mechanical support and provide secondary stability to the loosened femoral stem and can be considered a treatment option for low-demand patients. …”
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Whole genome studies of origin, selection and adaptation of the Russian cattle breeds by N. S. Yudin, D. M. Larkin

“…Whole-genome association studies of Russian cattle breeds pointed to a novel gene which could be related to the “white-faced” phenotype and to a gene which is related to body temperature support under the acute cold stress. …”
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Integrated Bioinformatics Identifies FREM1 as a Diagnostic Gene Signature for Heart Failure by Chenyang Jiang, Weidong Jiang

“…This study is aimed at integrating bioinformatics and machine learning to determine novel diagnostic gene signals in the progression of heart failure disease. …”
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Synthesis, Characterization, Optical and Dielectric Properties of NiO and Zn-Doped NiO Nanostructures: Toward Advanced Applications by Atizaz Ali, Sohail Ahmad, Muhammad Usman, Nangyaley Khan, Muhammad Hashim, Yasir Ali, Rasool Shah, Naveed Ur Rahman

“…This study unveils insights into the intricate optical and electrical properties of these novel nanostructures, showcasing their potential in advanced energy storage applications.…”
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Rheology and Stability of Hydrocarbon-Based Gelled Fuels for Airbreathing Applications by Simone Dell’Acqua, Francesco Morando, Stefania Carlotti, Filippo Maggi

“…A preliminary rheological analysis was conducted to characterize their behavior at rest and under shear stress. Finally, a novel approach was introduced to study the stability of the gels under vibration, which was derived from a realistic mission profile of a ramjet. …”
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Modeling to medical and economic data using: The transmuted power unit inverse Lindley distribution by Eman A. Eldessouky, Osama H. Mahmoud Hassan, Badr Aloraini, Ibrahim Elbatal

“…This study introduces the transmuted power unit inverse Lindley distribution (TPUILD) distribution as a novel extension of the power unit inverse Lindley distribution (PUILD), developed using a transmuted transformation technique to address existing challenges. …”
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