Common variants in left/right asymmetry genes and pathways are associated with relative hand skill. by William M Brandler, Andrew P Morris, David M Evans, Thomas S Scerri, John P Kemp, Nicholas J Timpson, Beate St Pourcain, George Davey Smith, Susan M Ring, John Stein, Anthony P Monaco, Joel B Talcott, Simon E Fisher, Caleb Webber, Silvia Paracchini

“…As PCSK6 is known to regulate NODAL in the development of left/right (LR) asymmetry in mice, we developed a novel approach to GWAS pathway analysis, using gene-set enrichment to test for an over-representation of highly associated variants within the orthologs of genes whose disruption in mice yields LR asymmetry phenotypes. …”
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Aircraft Detection for Remote Sensing Images Based on Deep Convolutional Neural Networks by Liming Zhou, Haoxin Yan, Yingzi Shan, Chang Zheng, Yang Liu, Xianyu Zuo, Baojun Qiao

“…Besides, to address the two problems simultaneously, this paper introduces the DAWM into the MSDN and names the novel network structure as Multiscale Refined Detection Network (MSRDN). …”
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The SPN Network for Digital Audio Data Based on Elliptic Curve Over a Finite Field by Ijaz Khalid, Tariq Shah, Khalid Ali Almarhabi, Dawood Shah, Muhammad Asif, M. Usman Ashraf

“…This manuscript presents a novel approach to the SPN (Substitution Permutation Network), for a new digital audio encryption scheme based on Mordell elliptic curve (MEC) over a finite prime field. …”
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Sandwich‐Structured Fluorinated Polyimide Aerogel/Paraffin Phase‐Change Composites Simultaneously Enables Gradient Thermal Protection and Electromagnetic Wave Transmission by Tao Shi, Jianwei Jing, Zhiqiang Qian, Gaojie Wu, Guofeng Tian, Huan Liu, Xiaodong Wang

“…Abstract There is an emerging requirement of advanced functional materials for simultaneous thermal protection and electromagnetic wave‐transparent transmission applications. A novel polyimide (PI) aerogel‐based sandwich‐structural composite is developed to meet such a requirement in this study. …”
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The Increasing Financial Impact of Chronic Kidney Disease in Australia by Patrick S. Tucker, Michael I. Kingsley, R. Hugh Morton, Aaron T. Scanlan, Vincent J. Dalbo

“…Per-patient, CKD produces a considerably greater financial impact on Australia’s healthcare system, compared to CVD. Research focusing on novel preventative/therapeutic interventions is warranted.…”
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Generalisation of EEG-Based Pain Biomarker Classification for Predicting Central Neuropathic Pain in Subacute Spinal Cord Injury by Keri Anderson, Sebastian Stein, Ho Suen, Mariel Purcell, Maurizio Belci, Euan McCaughey, Ronali McLean, Aye Khine, Aleksandra Vuckovic

“…PNP in datasets A and B separately; (2) classification between groups in datasets A and B together; and (3) classification where one dataset (A or B) was used for training and testing, and the other for validation. A novel normalisation method was applied to HFD features. …”
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Unveiling Tissue‐Specific RNA Landscapes in Mouse Organs During Fasting and Feeding Using Nanopore Direct RNA Sequencing by Chengfei Jiang, Ping Li, Haiming Cao

“…This study uncovered tens of thousands of novel transcripts and identified hundreds of genes with tissue‐specific expression, revealing additional layers of regulated pathways within each organ that conventional short‐read RNA‐seq cannot resolve. …”
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Changes to Intermediary Metabolites in Sporadic and LRRK2 Parkinson’s Disease Demonstrated by Proton Magnetic Resonance Spectroscopy by Jan O. Aasly, Oddbjørn Sæther, Krisztina K. Johansen, Tone F. Bathen, Guro F. Giskeødegård, Linda R. White

“…Potentially, 1H-MRS is a promising tool for identifying novel biomarkers for PD.…”
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Supervised contrastive pre-training models for mammography screening by Zhenjie Cao, Zhuo Deng, Zhicheng Yang, Jie Ma, Lan Ma

“…This paper presents a novel framework of Supervised Contrastive Pre-training followed by Supervised Fine-tuning (SCP+SF) for mammography screening. …”
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In Situ Aqueous Spice Extract-Based Antifungal Lock Strategy for Salvage of Foley’s Catheter Biofouled with <i>Candida albicans</i> Biofilm Gel by Bindu Sadanandan, Vaniyamparambath Vijayalakshmi, Kalidas Shetty, Adithya Rathish, Harshala Shivkumar, Malavika Gundreddy, Nikhil Kumar Kagganti Narendra, Nethra Machamada Devaiah

“…The study will provide an impetus to the development of novel spice extract-based ALT, reducing the selection pressure on the pathogen and lowering antimicrobial resistance. …”
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Existence of Pentatrichomonas hominis in Tibetan Antelope (Pantholops hodgsonii) by Shuo Liu, Shuo Liu, Jing-Hao Li, Si-Yuan Qin, Jing Jiang, Zhen-Jun Wang, Tao Ma, Jun-Hui Zhu, Hong-Li Geng, Wei-Lan Yan, Nian-Yu Xue, Yan Tang, He-Ting Sun

“…Additionally, the phylogenetic analysis indicated that most islolates belonged to the CC1 genotype, with one representing a potential novel genotype.DiscussionThis is the first s to report the presence of P. hominis in Tibetan antelopes, revealing that Tibetan antelopes may be a potential transmitter of zoontic P. hominis. …”
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Application of chemotactic behavior for life detection by Max Riekeles, Vincent Bruder, Vincent Bruder, Nicholas Adams, Berke Santos, Berke Santos, Dirk Schulze-Makuch, Dirk Schulze-Makuch, Dirk Schulze-Makuch

“…Methodologically, we introduce here a novel approach for utilizing µ-slides that diverges from the more traditional long-term chemotactic assay in favor of a shorter time frame assay that only requires a simple blob detection algorithm for microbial detection. …”
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Genetic optimization–based scheduling in maritime cyber physical systems by Tingting Yang, Hailong Feng, Jian Zhao, Ruilong Deng, Ying Wang, Zhou Su

“…Specially, the genetic based algorithm as well as the improved genetic based algorithm are described in detail, including a novel chromosome representation, a heuristic initialization procedure, as well as a modified crossover and mutation process. …”
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Application of geographic information system in ecotourism: a global bibliometric analysis by Amadua, Festus O., Nhamob, Luxon, Benzougagh, Brahim, Turyasingura, Benson

“…For example, GIS application is increasingly important in tourism through novel technologies like machine learning and remote sensing. …”
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Differentiating Between Perfluorohexyloctane Ophthalmic Solution and Water-Free Cyclosporine Ophthalmic Solution 0.1% for Dry Eye Disease: A Review of Preclinical and Clinical Char... by Laura M. Periman, Darrell E. White, Douglas Katsev

“…Perfluorohexyloctane (PFHO) uses a novel approach to treat evaporative DED, whereas water-free cyclosporine (CsA 0.1%) is formulated to increase ocular delivery of its active ingredient to improve tear production. …”
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The Effect of long-term rapamycin administration on intracellular calcium quantification and RhoA activity in kainic acid epilepsy model by Machlusil Husna, Kusworini Handono, Hidayat Sujuti, Aulanni’am Aulanni’am, Rumman Karimah, Afiyfah Kiysa Waafi, Alya Satira

“…This shows that there is still a need for novel anti-seizure medication that have different mechanisms. …”
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Research hotspots and frontiers in metakaolin-based geopolymer studies: a bibliometric analysis by Peng Wang, Mingquan Ma, Fei Wang

“…Abstract Metakaolin-based geopolymers, which are emerging as a novel and eco-friendly construction material, have garnered significant attention in recent years. …”
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Advancing Microchannel Fabrication: Tool-Innovated Die Sink Electrodischarge Machining by M. Shanmuka Srinivas, R. Meenakshi Reddy, Praveen Kumar Balguri, Din Bandhu, Manas Das, Kishore Debnath, Mridusmita Roy Choudhury

“…Stainless steel has long been celebrated for its exceptional corrosion resistance, durability, and versatility across a myriad of industrial applications. The novel tool design utilizes stainless-steel (Grade 301) blades to fabricate microchannels through die sink EDM on SS301 stainless-steel slabs. …”
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Research on Discriminative Skeleton-Based Action Recognition in Spatiotemporal Fusion and Human-Robot Interaction by Qiubo Zhong, Caiming Zheng, Haoxiang Zhang

“…A novel posture motion-based spatiotemporal fused graph convolutional network (PM-STGCN) is presented for skeleton-based action recognition. …”
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Recurrence of Herpetic Keratitis after COVID-19 Vaccination: A Report of Two Cases by Ali Mahdavi Fard, Jeffrey Desilets, Sangita Patel

“…The USFDA and WHO have acknowledged that the novel COVID-19 vaccines similarly have a risk of reactive immunologic-based inflammation, namely, myositis, pericarditis, and Guillain-Barré syndrome. …”
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