Interleukin-12p35 Deficiency Reverses the Th1/Th2 Imbalance, Aggravates the Th17/Treg Imbalance, and Ameliorates Atherosclerosis in ApoE-/- Mice by Ying Huang, Haiying Hu, Ling Liu, Jing Ye, Zhen Wang, Bin Que, Wenjing Liu, Ying Shi, Tao Zeng, Lei Shi, Qingwei Ji, Chao Chang, Yingzhong Lin

“…Interleukin- (IL-) 35, a novel functional cytokine of regulatory T cells (Treg) comprised of the IL-12p35 subunit and the other subunit Epstein-Barr virus-induced gene 3 (EBI3), regulates the activity of CD4+ T cells and macrophages, thereby playing a critical role in inflammatory and autoimmune diseases. …”
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Independent Modal Variable Structure Fuzzy Active Vibration Control of Cylindrical Thin Shells Laminated with Photostrictive Actuators by R.B. He, S.J. Zheng, H.T. Wang

“…However, it is unfortunate that the existing photostrictive actuator configuration can not induce negative membrane control forces. In this paper, a novel multi-layer actuator configuration is first presented to remedy this deficiency, followed by presenting the photostrictive/shell coupling equations of thin cylindrical shells laminated with the proposed multi-layer actuator configuration. …”
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Aspiration can decline epidemic disease by Khadija Khatun, Md. Mamun-Ur-Rashid Khan, Jun Tanimoto

“…The co-evolution of epidemic dynamics and individual decision-making is examined, utilizing the social efficiency deficit (SED) to quantify a social dilemma. A novel aspiration-based model is compared with the conventional cost-based model. …”
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Chondrogenic Potency Analyses of Donor-Matched Chondrocytes and Mesenchymal Stem Cells Derived from Bone Marrow, Infrapatellar Fat Pad, and Subcutaneous Fat by John Garcia, Claire Mennan, Helen S. McCarthy, Sally Roberts, James B. Richardson, Karina T. Wright

“…The findings from this study have significant clinical implications for the refinement and development of novel cell-based cartilage repair strategies.…”
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A telehealth-delivered intervention to extend the veteran HIV treatment cascade for cardiovascular disease prevention: V-EXTRA-CVD study protocol for a randomized controlled trial by Lewis Musoke, Hayden B. Bosworth, Christina Dickson, Pamela Gentry, Elizabeth Strawbridge, Soumya Subramaniam, Jennifer Gierisch, Valerie Smith, Sandra Woolson, John Pura, Willington Amutuhaire, Susanna Naggie, Julie Schexnayder, Karen Hall, Chris T. Longenecker, Nadine M. Harris, Chantrice Rogers, Puja Van Epps, for V-EXTRA-CVD Group

“…Conclusion: The proposed multicomponent intervention has the potential to improve cardiovascular outcomes in PWH using novel virtual care methods in a patient centered care approach.…”
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Theoretical and experimental studies on the interior ballistic of large UAV ejection based on trifluoromethane phase transition by Zhaijun Lu, Zhifu Wang, Shujian Yao, Mu Zhong, Kai Liu, Jiaqiang Wang

“…This research proposes the use of Trifluoromethane as a novel cold ejection medium. Trifluoromethane, being easily compressible, exhibiting high safety and low infrared characteristics, is well-suited for small-volume high-pressure chambers. …”
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The Role of Self-Efficacy and Religiosity in Determining Female Teachers' Resilience by Siti Marisa, Nurussakinah Daulay, Nefi Darmayanti, Noor Shakirah Mat Akhir

“…Data analysis was carried out using Structural Equation Modeling (SEM). This research offers novel insights into understanding resilience among female madrasah teachers by introducing religiosity as a moderating variable. …”
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Assessment of maternal health and behavior during pregnancy in the HEALthy Brain and Child Development Study: Rationale and approach by Kelly K. Gurka, Heather H. Burris, Lucia Ciciolla, Claire D. Coles, Suena H. Massey, Sharlene Newman, Vidya Rajagopalan, Lynne M. Smith, Anna Zilverstand, Gretchen Bandoli

“…Pregnancy, chronic and acute health conditions, family mental health, and healthcare utilization were assessed using existing and novel measures. Maternal mental health was assessed with the Edinburgh Postpartum Depression Scale, select items in the DSM-5 Self-Rated Level-1 and −2 Cross-Cutting Symptom Measures, and the National Stressful Events Survey-PTSD Short Scale. …”
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New insights in large-pores mesoporous silica microspheres for hemostatic application by Sara Saber Younes Mohamed, Roberta Cavalli, Elisabetta Rombi, Luciano Atzori, Marco Armandi, Barbara Onida

“…The data obtained showed that the modified MSM presents a surface able to adsorb a higher amount of water, compared to the pristine MSM, with a low molar heat of adsorption (about 35 kJ/mol), which renders the modified MSM presented in the present study an excellent candidate for producing novel hemostats. Graphical Abstract…”
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Ethanol Extract of Sesamum indicum Linn. Inhibits FcεRI-Mediated Allergic Reaction via Regulation of Lyn/Syk and Fyn Signaling Pathways in Rat Basophilic Leukemic RBL-2H3 Mast Cell... by Hyun Ju Do, Tae Woo Oh, Kwang-Il Park

“…The potent effect of SIE on RBL-2H3 mast cell activation indicates that the extract could potentially be used as a novel inhibitor against allergic reactions.…”
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Cardiac sound classification using a hybrid approach: MFCC-based feature fusion and CNN deep features by Mahbubeh Bahreini, Ramin Barati, Abbas Kamali

“…This paper presents a novel approach to PCG signal classification, leveraging a fusion of deep learning features and handcrafted features based on mutual information measurements. …”
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Geological characteristics of coal mines in the Zagros Basin of Iran: Unveiling rock mechanical properties and time-dependent behavior by Alireza Khoshmagham, Navid Hosseini Alaee, Reza Shirinabadi, Amir Hossein Bangian Tabrizi, Mehran Gholinejad, Pooria Kianoush

“…This study investigates the time-varying response of rocks and roof resistance in coal mines in the Zagros Mountains using a novel approach that combines numerical simulation, relaxation testing, and rock displacement studies. …”
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Biological insights into alleviating heavy metal toxicity through the simultaneous supply of biochar biofilters derived from the Mikania micrantha and molybdenum nanoparticles by Muhammad Shoaib Rana, Hongyu Chen, Shiwen Deng, Muhammad Imran, Yousif Abdelrahman Yousif Abdellah, Wanting Li, Jiayu Lin, Jiaxi Li, Ruilong Wang

“…Our findings showed that this novel combination significantly improved wheat physiological characteristics, growth, root architecture, elemental profile, osmoregulation, carotenoid, chlorophyll, gas exchange, and photosynthetic efficiency. …”
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Cyclic Training of Dual Deep Neural Networks for Discovering User and Item Latent Traits in Recommendation Systems by Dohyoung Rim, Sirojiddin Nuriev, Younggi Hong

“…This paper introduces Cyclic Dual Latent Discovery (CDLD), a novel method that employs dual deep neural networks (DNNs) in a cyclic training process to discover the latent traits of users and items based on their interactions. …”
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Myofibroblast-derived exosomes enhance macrophages to myofibroblasts transition and kidney fibrosis by Wenqiang Yu, Jinfang Song, Shuangquan Chen, Jiayi Nie, Chujun Zhou, Jiamin Huang, Hua Liang

“…Blockade of exosomes mediated myofibroblasts–macrophages communication may provide a novel therapeutic target for kidney fibrosis.…”
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Febuxostat Attenuates Renal Damage besides Exerting Hypouricemic Effect in Streptozotocin-Induced Diabetic Rats by Jianmin Ran, Gang Xu, Huixuan Ma, Hailing Xu, Yan Liu, Rongshao Tan, Ping Zhu, Jun Song, Gancheng Lao

“…In this study, we aimed to investigate the effects of febuxostat, a novel inhibitor of xanthine oxidase (XO), on renal damage in streptozotocin- (STZ-) induced diabetic rats. …”
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Neuronal Ensemble Decoding Using a Dynamical Maximum Entropy Model by Duho Sin, Jinsoo Kim, Jee Hyun Choi, Sung-Phil Kim

“…To address this issue, we develop a novel decoder that extends a maximum entropy decoder to take time-varying neural information into account. …”
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Petroselinum crispum extract ameliorates scopolamine-induced cognitive dysfunction: role on apoptosis, inflammation and oxidative stress by Göksel Şener, Gözde Karakadıoglu, Dilek Ozbeyli, Seren Ede, Refiye Yanardag, Ozlem Sacan, Asli Aykac

“…-treated scopolamine groups. On day 14, the novel object recognition test (NORT) and Morris water maze test (MWMT) were performed and then the rats were sacrificed. …”
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Microalga <i>Nannochloropsis gaditana</i> as a Sustainable Source of Bioactive Peptides: A Proteomic and In Silico Approach by Samuel Paterson, Laura Alonso-Pintre, Esperanza Morato-López, Sandra González de la Fuente, Pilar Gómez-Cortés, Blanca Hernández-Ledesma

“…This study highlights <i>N. gaditana</i>’s potential as a sustainable source of novel potential bioactive peptides with promising local and systemic biological effects.…”
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Voice EHR: introducing multimodal audio data for health by James Anibal, James Anibal, Hannah Huth, Ming Li, Lindsey Hazen, Veronica Daoud, Dominique Ebedes, Yen Minh Lam, Hang Nguyen, Phuc Vo Hong, Michael Kleinman, Shelley Ost, Christopher Jackson, Laura Sprabery, Cheran Elangovan, Balaji Krishnaiah, Lee Akst, Lee Akst, Ioan Lina, Iqbal Elyazar, Lenny Ekawati, Stefan Jansen, Richard Nduwayezu, Charisse Garcia, Jeffrey Plum, Jacqueline Brenner, Miranda Song, Emily Ricotta, Emily Ricotta, David Clifton, C. Louise Thwaites, Yael Bensoussan, Bradford Wood

“…Existing technologies depend on limited datasets collected with expensive recording equipment in high-income countries, which challenges deployment in resource-constrained, high-volume settings where audio data may have a profound impact on health equity.MethodsThis report introduces a novel protocol for audio data collection and a corresponding application that captures health information through guided questions.ResultsTo demonstrate the potential of Voice EHR as a biomarker of health, initial experiments on data quality and multiple case studies are presented in this report. …”
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