A Chinese Traditional Therapy for Bleomycin-Induced Pulmonary Fibrosis in Mice by Lifang Sun, Minjie Mao, Zhisheng Yan, Cuiyun Zuo, Xiaojie Zhang

“…In our study, Qingfei Xieding was investigated as a novel Chinese traditional patent medicine against pulmonary fibrosis. …”
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Helicobacter pylori Infection Elicits Type I Interferon Response in Human Monocytes via Toll-Like Receptor 8 Signaling by Chalystha Yie Qin Lee, Yee Teng Chan, Yi Ying Cheok, Grace Min Yi Tan, Ting Fang Tang, Heng Choon Cheong, Jamuna Vadivelu, Suhailah Abdullah, Chung Yeng Looi, Won Fen Wong

“…Additionally, TLR7/8 antagonist treatment reduced H. pylori infection-mediated phosphorylation of interferon regulatory factor 7 (IRF7). Our study suggests a novel role of TLR8 signaling in host immunity against H. pylori through sensing live bacteria to elicit the production of type I interferon.…”
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Optimized Naive-Bayes and Decision Tree Approaches for fMRI Smoking Cessation Classification by Amirhessam Tahmassebi, Amir H. Gandomi, Mieke H. J. Schulte, Anna E. Goudriaan, Simon Y. Foo, Anke Meyer-Baese

“…This paper aims at developing new theory-driven biomarkers by implementing and evaluating novel techniques from resting-state scans that can be used in relapse prediction for nicotine-dependent patients and future treatment efficacy. …”
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A Cryptographic Scheme for Construction of Substitution Boxes Using Quantic Fractional Transformation by Abid Mahboob, Muhammad Asif, Muhammad Nadeem, Aysha Saleem, Sayed M. Eldin, Imran Siddique

“…In this article, we proposed a novel technique to generate cryptographically strong S-box by using fractional transformation based on finite field. …”
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Nitrogen enrichment and vascular plant richness loss reduce bryophyte richness by Maeve Lin, Ariel Bergamini, Noémie A. Pichon, Eric Allan, Steffen Boch

“…Our results highlight novel mechanisms by which land-use intensification can affect bryophytes and suggest that a loss of vascular plant richness might have cascading effects on other taxonomic groups.…”
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Development of a fixed-order $$H_{\infty }$$ controller for a robust P&O-MPPT strategy to control poly-crystalline solar PV energy systems by Moussa Sedraoui, Mohcene Bechouat, Ramazan Ayaz, Yahya Z. Alharthi, Abdelhalim Borni, Layachi Zaghba, Salah K. ElSayed, Yayehyirad Ayalew Awoke, Sherif S. M. Ghoneim

“…Abstract This paper presents a novel approach to modeling and controlling a solar photovoltaic conversion system(SPCS) that operates under real-time weather conditions. …”
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Reusable Biosensor for Easy RNA Detection from Unfiltered Saliva by Paweł Wityk, Agata Terebieniec, Robert Nowak, Jacek Łubiński, Martyna Mroczyńska-Szeląg, Tomasz Wityk, Dorota Kostrzewa-Nowak

“…This study introduces a novel, reusable biosensor designed for direct viral RNA detection from unfiltered saliva, targeting SARS-CoV-2. …”
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Current Treatment Regimens and Promising Molecular Therapies for Chronic Hepatobiliary Diseases by Marilena Durazzo, Arianna Ferro, Victor Manuel Navarro-Tableros, Andrea Gaido, Paolo Fornengo, Fiorella Altruda, Renato Romagnoli, Søren K. Moestrup, Pier Luigi Calvo, Sharmila Fagoonee

“…Further, we describe how this knowledge is linked to current molecular therapies as well as ongoing preclinical and clinical research on novel targeting strategies, including nucleic acid-, mesenchymal stromal/stem cell-, and extracellular vesicle-based options. …”
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Biomineralized PEEK cages containing osteoinductive CaP bioceramics promote spinal fusion in goats by Qiujiang Li, Bowen Hu, Linan Wang, Lei Wang, Cong Feng, Zhuang Zhang, Zhipeng Deng, Yang Xiao, Bo Yuan, Xiangdong Zhu, Xiangfeng Li, Xi Yang, Yueming Song, Xingdong Zhang

“…Polyetheretherketone (PEEK) has become a commonly used alternative material for fusion cages owing to its excellent mechanical properties and biocompatibility, but its biological inertness limits bone regeneration and may lead to poor fusion. In this study, a novel strategy for preparing bioactive biomineralized PEEK cages was developed using a unique combination of osteoinductive CaP bioceramic fillings in the cage window, acid sulfonation and simulated body fluid incubation. …”
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The protective effects of peptides from Chinese baijiu on AAPH-induced oxidative stress in HepG2 cells via Nrf2-mediated signaling pathway by Jiaying Huo, Yuezhang Ming, Huifeng Li, Anjun Li, Jiwen Zhao, Mingquan Huang, Weizheng Sun, Jihong Wu, Jinglin Zhang

“…However, only a few reports have been published examining the antioxidant peptides derived from Chinese baijiu. In this study, 6 novel peptides derived from Chinese baijiu were identified successfully using high-performance liquid chromatography-quadrupole-time-of-flight mass spectrometry (HPLC-QTOF-MS) with a concentration of 0.835–24.540 µg/L. …”
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Gingiva-Derived Mesenchymal Stem Cells Attenuate Imiquimod- (IMQ-) Induced Murine Psoriasis-Like Skin Inflammation by Ziyu Ye, Yanfang Liang, Bihua Lin, Yanyun Li, Xingxing Chai, Jiachun Lian, Xueying Zhang, Zhengping Che, Jincheng Zeng

“…Here, we isolated and characterized GMSCs in 2D and 3D culture conditions and found that GMSCs in 2D and 3D infusion can significantly ameliorate the IMQ-induced murine psoriasis-like skin inflammation, reduce the levels of Th1- and Th17-related cytokines IFN-γ, TNF-α, IL-6, IL-17A, IL-17F, IL-21, and IL-22, and upregulate the percentage of spleen CD25+CD3+ T cells while downregulate the percentage of spleen IL-17+CD3+ T cells. In summary, our novel findings reveal that GMSCs in 2D and 3D infusion may possess therapeutic effects in the treatment of psoriasis.…”
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Bibliometrics of the current state of application of teletechnology in the rehabilitation of patients with heart and large blood vessel disease by Sican Wang, Ping Yu, Xuemei Zhou, Yuan Yuan, Jian Chen, Dongmei Chen, Jingyan Liang, Jingyan Liang, Li Xu

“…To bridge this gap, bibliometrics was used, a novel approach to determine the most prolific countries, institutions, journals, authors, source topics, funding agencies, and the most popular category of remote technologies and solutions for disease rehabilitation. …”
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OBTPN: A Vision-Based Network for UAV Geo-Localization in Multi-Altitude Environments by Nanxing Chen, Jiqi Fan, Jiayu Yuan, Enhui Zheng

“…In this paper, we propose a novel end-to-end network, OBTPN. In the initial phase of the model, we optimized the distribution of attention within the primary network, aiming to achieve a balance between self-attention and cross-attention. …”
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Isolation and identification of Starmerella davenportii strain Do18 and its application in black tea beverage fermentation by Chuanhai Tu, Wenxiu Hu, Sijie Tang, Ling Meng, Zhihai Huang, Xiao Xu, Xiudong Xia, Fidelis Azi, Mingsheng Dong

“…The objective of this study was to isolate and identify a yeast strain from the kombucha beverage and evaluate in-vitro its potential as a novel starter in beverage fermentation. Starmerella davenportii Do18 was characterized for its cholesterol reduction; growth at different conditions such as temperatures (25, 30, 37 and 42 °C), low pH (1.2, 1.5, 2.0 3.0, and 7.0), bile salts (0%, 0.25%, 0.5%, 1% and 2%) high-sucrose stress (2%, 10%, 20%, 40% and 60%); and in-vitro survival in gastric and intestinal environments. …”
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Emerging PPARγ-Independent Role of PPARγ Ligands in Lung Diseases by Ajit A. Kulkarni, Collynn F. Woeller, Thomas H. Thatcher, Sesquile Ramon, Richard P. Phipps, Patricia J. Sime

“…These PPARγ-independent mechanisms are of significant interest because they suggest new therapeutic uses for currently approved drugs and because they can be used as probes to identify novel proteins and pathways involved in the pathogenesis or treatment of disease, which can then be targeted for further investigation and drug development.…”
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Deep Learning Framework for Advanced De-Identification of Protected Health Information by Ahmad Aloqaily, Emad E. Abdallah, Rahaf Al-Zyoud, Esraa Abu Elsoud, Malak Al-Hassan, Alaa E. Abdallah

“…This paper introduces a novel approach, leveraging a Bi-LSTM-CRF model to achieve accurate and reliable PHI de-identification, using the i2b2 dataset sourced from Harvard University. …”
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Integrating Energy and Time Efficiency in Robotic Manufacturing Cell Design: A Methodology for Optimizing Workplace Layout by Roman Ruzarovsky, Tibor Horak, Robert Bocak, Martin Csekei, Roman Zelník

“…This paper presents a novel methodology for optimizing the deployment of industrial robots and their peripherals, focusing on minimizing energy and time costs to enhance the sustainability of industrial processes. …”
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Profiling the Secretome of Glioblastoma Cells Under Histone Deacetylase Inhibition Using Mass Spectrometry by Aline Menezes, Yara Martins, Fábio Nogueira, Denise De Abreu Pereira, Katia Carneiro

“…The main challenge in GBM research has been to identify novel molecular therapeutic targets and accurate diagnostic/prognostic biomarkers. …”
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Developing company competitiveness based on entrepreneurial values, transformational leadership, and service innovation through organizational performance by Solikin Solikin, Muhammad Thamrin, Suharto Abdul Majid, Librita Arifiani

“…These results support a novel empirical model of how entrepreneurial values, transformational leadership, and service innovation affect company competitivenessby using organizational performance as a mediating factor. …”
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Genomic adaptation of Clostridium perfringens to human intestine by Ke Wu, Juan Wang, Zelin Yan, Yanyan Zhu, Shaolin Wang, Bo Fu, Chengtao Sun, Ruichao Li, Edward M. Fox, Séamus Fanning, Li Bai, Yang Wang, Yizhi Tang, Zhe Yin, Rong Zhang, Hongning Wang

“…Through this comprehensive genomic analysis, we provide novel insights into the fusion of pCW3‐like and pCP13‐like plasmids, the genetic location of cpe, the transmission dynamics of C. perfringens strains, and the relationship between toxin genes and host relevance. …”
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