ARCS: Adaptive Reinforcement Learning Framework for Automated Cybersecurity Incident Response Strategy Optimization by Shaochen Ren, Jianian Jin, Guanchong Niu, Yang Liu

“…This paper presents ARCS (Adaptive Reinforcement learning for Cybersecurity Strategy), a novel framework that leverages deep reinforcement learning to optimize automated incident response strategies in cybersecurity systems. …”
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Targeted nanoliposomes for precision rheumatoid arthritis therapy: a review on mechanisms and in vivo potential by Rushikesh Girase, Nayan A. Gujarathi, Amey Sukhia, Sri Sai Nikitha Kota, Tulshidas S. Patil, Abhijeet A. Aher, Yogeeta O. Agrawal, Shreesh Ojha, Charu Sharma, Sameer N. Goyal

“…It highlights the pathophysiology of RA, explores selective targeting sites, and elucidates diverse mechanisms of novel liposomal types and their applications. Furthermore, the targeting strategies of pH-sensitive, flexible, surface-modified, PEGylated, acoustic, ROS-mediated, and biofunctionalized liposomes are addressed. …”
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Microwave-Assisted Method for Simultaneous Hydrolysis and Extraction for Preparation of Geniposidic Acid from Eucommia ulmoides Bark Using Basic Imidazolide Ionic Liquid by Lili Li, Yupin Guo, Chunchao Zhao, Mengxia Wei, Junling Liu, Yuangang Zu, Fei Wang, Lei Yang

“…In order to hydrolyze geniposide and extract geniposidic acid, a novel microwave irradiation heating method for simultaneous hydrolysis and extraction for preparation of geniposidic acid from Eucommia ulmoides bark using basic imidazolide ionic liquid was developed in this work. …”
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Incremental Graph Regulated Nonnegative Matrix Factorization for Face Recognition by Zhe-Zhou Yu, Yu-Hao Liu, Bin Li, Shu-Chao Pang, Cheng-Cheng Jia

“…To address this problem, In this paper, firstly, we proposed a novel subspace incremental method called incremental graph regularized nonnegative matrix factorization (IGNMF) algorithm which imposes manifold into incremental nonnegative matrix factorization algorithm (INMF); thus, our new algorithm is able to preserve the geometric structure in the data under incremental study framework; secondly, considering we always get many face images belonging to one person or many different people as a batch, we improved our IGNMF algorithms to Batch-IGNMF algorithms (B-IGNMF), which implements incremental study in batches. …”
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Optimization of Carrier-Based Dry Powder Inhaler Performance: A Review by Tanu Mehta, Saeed Najafian, Komalkumar Patel, Justin Lacombe, Bodhisattwa Chaudhuri

“…This review will discuss different factors influencing the aerosol performance of carrier-based DPIs, including formulation components, device considerations, and manufacturing parameters. Additionally, novel technologies pertaining to the optimization of DPI performance are also discussed.…”
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Non-Canonical, Extralysosomal Activities of Lysosomal Peptidases in Physiological and Pathological Conditions: New Clinical Opportunities for Cancer Therapy by Ryan Conesa-Bakkali, Macarena Morillo-Huesca, Jonathan Martínez-Fábregas

“…Furthermore, some lysosomal proteases are no longer restricted to the lysosomal compartment, as more novel non-canonical, extralysosomal targets are being identified. …”
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Estimation and Characterization of Dengue Serotypes in Patients Presenting with Dengue Fever at Makkah Hospitals by Sami Melebari, Abdul Hafiz, Hatim A. Natto, Mohamed Osman Elamin, Naif A. Jalal, Ashwaq Hakim, Safiah Rushan, Othman Fallatah, Kamal Alzabeedi, Feras Malibari, Hutaf Mashat, Aisha Alsaadi, Amani Alhakam, Anoud Hadidi, Ghazi Saad Alkhaldi, Ahmed Alkhyami, Ali Alqarni, Abdulaziz Alzahrani, Mohammed Alghamdi, Abdullah Siddiqi, Abdullah Alasmari, Rowaida Bakri, Saleh Alqahtani, Juman M. Al-Bajaly, Asim Khogeer

“…Since Makkah receives numerous international travelers, these samples might contain novel dengue serotypes circulating in different parts of the world. …”
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Collaborative modification strategy to improve the formation of biochar-derived persistent free radicals for aniline removal via peroxymonosulfate activation by Zilong Zhao, Shuting Zhu, Shuyu Qi, Ting Zhou, Yang Yang, Feng Wang, Qi Han, Wenyi Dong, Hongjie Wang, Feiyun Sun

“…Abstract This study explores a novel approach to biochar modification aimed at increasing persistent free radical (PFR) formation on biochar surfaces, thereby enhancing aniline removal via peroxymonosulfate (PMS) activation. …”
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Toward Design of a Drip-Stand Patient Follower Robot by Zewen Wu, Shahram Payandeh

“…We applied a pinhole camera model for the estimation of distance from the robot to the patient. We proposed a novel movement trajectory planner to maintain the dynamic tipping stability of the robot by adjusting the peak acceleration. …”
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Thermodynamics guided design and processing of a WC/HEA cermet tool for high temperature friction stir welding by Supreeth Gaddam, Surekha Yadav, Amit Kishan Behera, Noriaki Arai, Zaynab Mahbooba, Shikhar Krishn Jha, Qiaofu Zhang, Rajiv S. Mishra

“…This study is the first proof-of-concept for the design, fabrication, testing, and evaluation of a novel cermet FSW tool material with low-cost and high-performance synergy for high temperature FSW application.…”
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Thermal behavior of silica aerogel-paraffin nanocomposites in a nanochannel under varying magnetic fields: A molecular dynamics study by Yi Ru, Ali B.M. Ali, Shahram Babadoust, Rasha Abed Hussein, Mohammed Al-Bahrani, Barno Abdullaeva, Soheil Salahshour, S. Mohammad Sajadi, Sh Esmaeili

“…This study presented a novel analysis of how various magnetic field strengths (ranging from 0 to 0.5 T) affected the thermal behavior of a nanostructure composed of silica aerogel, paraffin, and CuO nanoparticles in a cylindrical tube. …”
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Low-Rank Adaptation of Pre-Trained Large Vision Models for Improved Lung Nodule Malignancy Classification by Benjamin P. Veasey, Amir A. Amini

“…Inspired by LoRA's success in the field of Natural Language Processing, we hypothesized that such an adaptation technique can significantly improve classification performance, parameter efficiency, and training speed for the novel application of lung image cancer diagnostic. …”
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Perilipin 2 Impacts Acute Kidney Injury via Regulation of PPARα by Sujuan Xu, Edward Lee, Zhaoxing Sun, Xiaoyan Wang, Ting Ren, Zhouping Zou, Jifu Jin, Jie Li, Jian Zhang, Yingxiang Li, Qiang Yang, Yang Zhang, Man Guo, Yi Fang, Xiaoqiang Ding

“…Consequently, the downregulation of Plin2 could be a novel therapeutic strategy for AKI.…”
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Reinforcement Learning-Based Resource Allocation Scheme of NR-V2X Sidelink for Joint Communication and Sensing by Zihan Li, Ping Wang, Yamin Shen, Song Li

“…In order to overcome the challenges in the distributed resource allocation of sidelink JCS with a full-duplex, this paper has proposed a novel consecutive-collision mitigation semi-persistent scheduling (CCM-SPS) scheme, including the collision detection and Q-learning training stages to suppress collision probabilities. …”
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A Modified Salp Swarm Algorithm Based on the Perturbation Weight for Global Optimization Problems by Yuqi Fan, Junpeng Shao, Guitao Sun, Xuan Shao

“…To overcome the poor real-time performance and low precision of the basic salp swarm algorithm, this paper introduces a novel hybrid algorithm inspired by the perturbation weight mechanism. …”
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Cytoskeletal Vimentin Directs Cell‐Cell Transmission of Hepatitis C Virus by Yifan Xing, Zeyu Wen, Jie Mei, Xinyi Huang, Shuangshuang Zhao, Jin Zhong, Yaming Jiu

“…Together, the results unveil an unrecognized function of vimentin as a unique venue dominating viral transmission, providing novel insights into propelling advancements in vimentin‐targeted anti‐HCV therapies.…”
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RenalSegNet: automated segmentation of renal tumor, veins, and arteries in contrast-enhanced CT scans by Rashid Khan, Chao Chen, Asim Zaman, Jiayi Wu, Haixing Mai, Liyilei Su, Yan Kang, Bingding Huang

“…This study presents RenalSegNet, a novel deep-learning framework for automatically segmenting renal structure in contrast-enhanced CT images. …”
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Mesenchymal Stem Cells Pretreated with HGF and FGF4 Can Reduce Liver Fibrosis in Mice by Sulaiman Shams, Sadia Mohsin, Ghazanfar Ali Nasir, Mohsin Khan, Shaheen N. Khan

“…These results demonstrated the potential utility of this novel idea of cytokines pretreated MSCs for the treatment of liver fibrosis.…”
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Mechanical properties and energy absorption of CoCrNi functionally graded TPMS cellular structures by Zhaoyi Wang, Junxian Zhou, Yunzhuo Lu, Dongming Li, Deyu Yue, Xu Zhang, Bingzhi Chen

“…By integrating appropriate parameter mapping, the mechanical properties can be predicted and regulated more flexibly, thereby paving the way for novel high-performance energy-absorbing structures.…”
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Unveiling the new chapter in nanobody engineering: advances in traditional construction and AI-driven optimization by Jiwei Liu, Lei Wu, Anqi Xie, Weici Liu, Zhao He, Yuan Wan, Wenjun Mao

“…AI’s exceptional performance in protein structure prediction and molecular interaction simulation has introduced novel perspectives and tools for Nb design and optimization. …”
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