Enhanced ferroptosis sensitivity promotes the formation of highly myopic cataract via the DDR2-Hippo pathway by Dongling Guo, Yu Du, Xin Liu, Dan Li, Ling Wei, Xiangjia Zhu

“…Altogether, these findings highlighted the role of DDR2 in mediating ferroptosis in HMC formation, providing a novel insight for therapeutic interventions.…”
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Lightweight marine biodetection model based on improved YOLOv10 by Wei Pan, Jiabao Chen, Bangjun Lv, Likun Peng

“…Addressing these issues, the lightweight YOLOv10-AD model introduces AKVanillaNet, a novel backbone optimized for the distinct shapes of marine organisms, improving detection accuracy while minimizing parameters and computational cost. …”
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Effects of CeO2/Y2O3 rare earth oxides on microstructure and properties of in-situ synthesized WC-reinforced Ni-based cladding layer by Zhang C. X., Sun W. C., Liu E. Y., Liu Y. W., Liu J. P., Zhang B., Xu Y. F., Zhou M. R.

“…A novel tungsten carbide (WC)-reinforced nickel (Ni)-based laser cladding layer was prepared through an in-situ synthesis process. …”
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Fine tuning enzyme activity assays for monitoring the enzymatic hydrolysis of PET by Krisztina Boros, Blanka Eszter Nagy, Raluca Bianca Tomoiagă, Róbert Tőtős, Monica Ioana Toșa, Csaba Paizs, László Csaba Bencze

“…Abstract Efficient monitoring of the enzymatic PET-hydrolysis is crucial for developing novel plastic-degrading biocatalysts. Herein, we aimed to upgrade in terms of accuracy the analytical methods useful for monitoring enzymatic PET-degradation. …”
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A TaqMan Real-Time PCR Assay for Detection and Quantification of Sporisorium scitamineum in Sugarcane by Yachun Su, Shanshan Wang, Jinlong Guo, Bantong Xue, Liping Xu, Youxiong Que

“…Furthermore, quantification of pathogen was verified in pathogen-challenged buds in different sugarcane genotypes, which suggested its feasibility for evaluation of smut resistance in different sugarcane genotypes. Taken together, this novel assay can be used as a diagnostic tool for sensitive, accurate, fast, and quantitative detection of the smut pathogen especially for asymptomatic seed cane or plants and evaluation of smut resistance of sugarcane genotypes.…”
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Study of Chemical Intermediates by Means of ATR-IR Spectroscopy and Hybrid Hard- and Soft-Modelling Multivariate Curve Resolution-Alternating Least Squares by Junxiu Ma, Juan Qi, Xinyu Gao, Chunhua Yan, Tianlong Zhang, Hongsheng Tang, Hua Li

“…The aim of this study is to investigate the ability of online attenuated total reflection infrared (ATR-IR) spectroscopy combined with the novel approach of hybrid hard- and soft-modelling multivariate curve resolution-alternating least squares (HS-MCR) analysis to monitor and detect changes in structural properties of compound during 3,5-diamino-1,2,4-triazole (DAT) synthesis processes. …”
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A critical review of compensation converters for capacitive power transfer in wireless electric vehicle charging circuit topologies by Mohammad Amir, Izhar Ahmad Saifi, Mohammad Waseem, Mohd Tariq

“…Additionally, it presented a novel conformal bumper-based approach, highlighting its distinct advantages compared to alternative charging methods. …”
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PPAR-γ Regulates Trophoblast Differentiation in the BeWo Cell Model by Khrystyna Levytska, Sascha Drewlo, Dora Baczyk, John Kingdom

“…Here, we aimed to characterize the baseline activity of PPAR-γ in the human choriocarcinoma BeWo cell line that mimics SCT formation in vitro and modulate PPAR-γ activity to study its effects on cell proliferation versus differentiation. We report a novel negative autoregulatory mechanism between PPAR-γ activity and expression and show that blocking PPAR-γ activity induces cell proliferation at the expense of differentiation, while these remain unaltered following treatment with the agonist rosiglitazone. …”
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The effect of rotating magnetic turbulators on the convective heat transfer and pressure drop through a circular tube: Experimental investigation by Seyyed Morteza Mansouri, Mohamad Ali Bijarchi, L Siamak K Kazemzadeh Hannani

“…In this study, forced convective heat transfer inside a tube is investigated by introducing a novel active method that uses an external rotational magnetic field to rotate magnetic spheres in a tube under constant heat flux. …”
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Open-world barely-supervised learning via augmented pseudo labels by Zhongnian Li, Yanyan Ding, Meng Wei, Xinzheng Xu

“…To tackle the OWBSL task, we proposed a novel framework that leveraged augmented pseudo-labels generated for the unlabeled data. …”
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Development of new SSR markers for homoeologous WFZP loci based on the study of structure and location of microsatellites in gene-rich regions of chromosomes 2AS , 2BS, 2DS by O. B. Dobrovolskaya, C. Pont, Yu. L. Orlov, J. Salse

“…Identification and study of the distribution of SSR loci in gene-rich regions of the bread wheat genome and development of novel SSR markers based on these data are of practical interest, being important for the study of bread wheat genome organization. …”
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Serous Retinal Detachment Associated with Dome-Shaped Macula and Staphyloma Edge in Myopic Patients before and after Treatment with Spironolactone by Álvaro Fernández-Vega Sanz, Carlos Mario Rangel, Eva Villota Deleu, Beatriz Fernández-Vega Sanz, Ronald Mauricio Sánchez-Ávila

“…Conclusions. We evaluated a novel treatment for SRD associated with DSM and staphyloma margin in myopic patients. …”
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Central amygdala neuroimmune signaling in alcohol use disorder by Mariam Melkumyan, Patrick A. Randall, Yuval Silberman

“…Current treatments for AUD, including FDA-approved medications such as naltrexone and acamprosate, have limited efficacy and compliance, underscoring the need for novel therapeutic approaches. The central amygdala (CeA) plays a crucial role in the development and maintenance of AUD, particularly aspects associated with stress and binge behaviors. …”
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IL-6 is Upregulated in Late-Stage Disease in Monkeys Experimentally Infected with Trypanosoma brucei rhodesiense by Dawn Nyawira Maranga, John Maina Kagira, Christopher Kariuki Kinyanjui, Simon Muturi Karanja, Naomi Wangari Maina, Maina Ngotho

“…The management of human African trypanosomiasis (HAT) is constrained by lack of simple-to-use diagnostic, staging, and treatment tools. The search for novel biomarkers is, therefore, essential in the fight against HAT. …”
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Hospital-Acquired COVID-19: Case Discussions of Two Patients Treated at a Level I Trauma Center by Ryan M. Desrochers, Jonathan D. Gates, Daniel Ricaurte, Jane J. Keating

“…This is important to consider not only for COVID-19 but also for future novel infectious diseases.…”
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Laser Welding of Micro-Wire Stent Electrode as a Minimally Invasive Endovascular Neural Interface by Bo Wen, Liang Shen, Xiaoyang Kang

“…To ensure consistent results, a novel micro-wire welding with platinum pad method was introduced during the welding process. …”
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Fat Reduction and Replacement in Dry-Cured Fermented Sausage by Using High Pressure Processing Meat as Fat Replacer and Olive Oil by Bolumar Tomas, Toepfl Stefan, Heinz Volker

“…High pressure processing (HPP) treated meat was employed as a novel fat replacer to reduce the fat content and as a new strategy to enable a stable incorporation of olive oil in dry-cured fermented sausages. …”
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Knowledge Management in Road Accident Detection Based on Developed Deep Learning by Bvss Subbarao, Ramana K

“…This paper introduces novel types of deep learning for accident detection.…”
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A generalized interval-valued p,q Rung orthopair fuzzy Maclaurin symmetric mean and modified regret theory based sustainable supplier selection method by Shuang Chen, Jian Ren, KeTing Ye, FeiYan Li

“…Abstract A novel interval valued p,q Rung orthopair fuzzy (IVPQ-ROF) multiple attribute group decision making (MAGDM) method for sustainable supplier selection (SSS) is proposed in this paper. …”
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New therapies in pulmonary arterial hypertension: Recent insights by Giulia Guglielmi, Konstantinos Dimopoulos, S. John Wort

“…Current therapies primarily focus on pulmonary vasodilation; however, novel approaches that target the underlying pathophysiological mechanisms—such as TGF-β signalling, epigenetic alterations, growth factors, inflammation, and extracellular matrix remodelling—are promising alternatives for improving treatment outcomes. …”
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