A deep learning-driven multi-layered steganographic approach for enhanced data security by Yousef Sanjalawe, Salam Al-E’mari, Salam Fraihat, Mosleh Abualhaj, Emran Alzubi

“…This paper addresses key limitations of traditional steganographic methods, such as limited payload capacity, susceptibility to detection, and lack of robustness against attacks. A novel multi-layered steganographic framework is proposed, integrating Huffman coding, Least Significant Bit (LSB) embedding, and a deep learning-based encoder–decoder to enhance imperceptibility, robustness, and security. …”
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Design and implementation of a solar powered kit for measurement and logging of environmental parameters using the SEN55 sensor by J. Nchi Muhvu, M.D. Fendji, C.M. Ekengoue

“…The study underscores the device's ability to enhance environmental awareness, guide public health initiatives, and promote sustainable alternatives like solar energy systems. This novel system contributes to advancing air quality monitoring, offering a scalable and impactful solution for reducing pollution and safeguarding health.…”
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T cell related osteoimmunology in fracture healing: Potential targets for augmenting bone regeneration by Haixing Wang, Yashi Li, Haoxin Li, Xu Yan, Zhaowei Jiang, Lu Feng, Wenhui Hu, Yinuo Fan, Sien Lin, Gang Li

“…Developing a deep understanding of the roles of immune cells, including T cells, in fracture healing will facilitate the advancement of novel therapeutics of fracture nonunion. This review summarizes the current understanding of different T cell subsets involved in various phases of fracture healing, providing insights for targeting T cells as an alternative strategy to enhance bone regeneration.…”
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A Hybrid Random Forest and Least Squares Support Vector Machine Model Based on Particle Swarm Optimization Algorithm for Slope Stability Prediction: A Case Study in Sichuan–Tibet H... by Tao Shu, Wei Tao, Haotian Lu, Hao Li, Jingxuan Cao

“…The results provide a novel approach toward slope stability prediction in the field of geotechnical engineering.…”
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MicroRNA-155: Regulation of Immune Cells in Sepsis by Ming Chen, Fuquan Wang, Haifa Xia, Shanglong Yao

“…In addition, by blocking the proinflammatory effects of miR-155, it can effectively improve sepsis-related organ injury, providing novel insights to identify potential biomarkers and therapeutic targets for sepsis. …”
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Improved brain functional network in major depressive disorder with suicidal ideation after individual target-transcranial magnetic stimulation treatment: a graph-theory analysis by Yao Zhang, Nan Mu, Shun Qi, Chuanzhu Sun, Yang Rao, Xinyi Yang, Jianying Guo, Yunfeng Mu

“…There is an urgent need for clarifying the pathogenesis and developing novel treatment methods.MethodsSubjects were recruited for the collection of Magnetic Resonance Imaging data and clinical scales. …”
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Deficiency of orexin receptor type 1 in dopaminergic neurons increases novelty-induced locomotion and exploration by Xing Xiao, Gagik Yeghiazaryan, Fynn Eggersmann, Anna Lena Cremer, Heiko Backes, Peter Kloppenburg, Anne Christine Hausen

“…Deletion of Ox1R increased locomotor activity and exploration during exposure to novel environments or when intracerebroventricularely injected with orexin A. …”
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Overcoming beta-lactam resistance in Pseudomonas aeruginosa by targeting metallo-beta-lactamase VIM-1: a one-microsecond molecular dynamics simulation study by Mohammed Salleh M. Ardawi, Samar A. Badreddine, Muhammad Yasir, Muhammad Yasir, Aiah M. Khateb, Aiah M. Khateb, Safaa A. Turkistani, Ahmed Afandi, Samah O. Noor, Adhari Alselmi, Adhari Alselmi, Vivek Dhar Dwivedi, Vivek Dhar Dwivedi, Esam I. Azhar, Esam I. Azhar

“…The identified compounds offer a promising avenue for developing novel therapeutics to restore the efficacy of beta-lactam antibiotics against resistant bacterial strains. …”
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MISO intuitionistic fuzzy inference system by Lakshmana Nayagam Velu, Daniel Paulraj

“…To demonstrate the utility of this approach, the study applies a trapezoidal intuitionistic fuzzy inference system (TIFIS) to model COVID-19 risk, assuming expert data may exhibit varying degrees of confidence. This novel framework significantly enhances decision-making processes in complex, uncertain environments, offering a robust alternative to existing FIS models.…”
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A Scalable Framework for Sensor Data Ingestion and Real-Time Processing in Cloud Manufacturing by Massimo Pacella, Antonio Papa, Gabriele Papadia, Emiliano Fedeli

“…This study presents a novel nine-layer architecture designed specifically to address these issues. …”
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A Microfluidic Paper-Based Device for Monitoring Urease Activity in Saliva by Francisca T. S. M. Ferreira, António O. S. S. Rangel, Raquel B. R. Mesquita

“…This work introduces a novel 3D µPAD for quantifying urease activity in saliva in a range of 0.041–0.750 U/mL, with limits of detection and quantification of 0.012 and 0.041 U/mL, respectively. …”
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LncRNA PVT1 links estrogen receptor alpha and the polycomb repressive complex 2 in suppression of pro-apoptotic genes in hormone-responsive breast cancer by Viola Melone, Domenico Palumbo, Luigi Palo, Noemi Brusco, Annamaria Salvati, Antonietta Tarallo, Giorgio Giurato, Francesca Rizzo, Giovanni Nassa, Alessandro Weisz, Roberta Tarallo

“…Abstract RNA-based therapeutics highlighted novel approaches to target either coding or noncoding molecules for multiple diseases treatment. …”
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Advanced Driver-Assistance System (ADAS) for Intelligent Transportation Based on the Recognition of Traffic Cones by Liyong Wang, Peng Sun, Min Xie, Shaobo Ma, Boxiong Li, Yuchen Shi, Qinghua Su

“…The result indicates that this novel method could recognize the red, blue, and yellow traffic cones with 85%, 100%, and 100% success rate, respectively, while maintaining 90% accuracy in traffic-cone distance sensing. …”
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High Intestinal and Systemic Levels of Interleukin-23/T-Helper 17 Pathway in Chinese Patients with Inflammatory Bowel Disease by Lu Song, Rui Zhou, Sha Huang, Feng Zhou, Shufang Xu, Wei Wang, Fengming Yi, Xiaobing Wang, Bing Xia

“…Taken together, our results provided evidence that IL-23/Th17 pathway genes may represent important biomarkers of active stage of IBD and serve as novel therapeutic targets for IBD in Chinese population.…”
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Comparative Modeling and Molecular Dynamics Simulation of Substrate Binding in Human Fatty Acid Synthase: Enoyl Reductase and β-Ketoacyl Reductase Catalytic Domains by Arun John, Vetrivel Umashankar, Subramanian Krishnakumar, Perinkulam Ravi Deepa

“…Thus, the predicted models yielded significant insights into the substrate binding modes of the ER and KR catalytic domains and will aid in identifying novel chemical inhibitors of human FASN that target these domains.…”
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A Correlation Analysis-Based Structural Load Estimation Method for RC Beams Using Machine Vision and Numerical Simulation by Chun Zhang, Yinjie Zhao, Guangyu Wu, Han Wu, Hongli Ding, Jian Yu, Ruoqing Wan

“…The classical regression assessment method based on experimental data not only relies on costly structure experiments; it also lacks interpretability. Therefore, a novel load estimation method for RC beams, based on correlation analysis between detected crack images and strain contour plots calculated by FEM, is proposed. …”
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Run-Time Value Chain Analysis and Cost Accounting via Microservices in Agile Manufacturing by Salman Javed, Cristina Paniagua, Imran Javed, Jan van Deventer, Jerker Delsing

“…This article presents a novel two-stage VCA approach using an activity-based costing mechanism via microservices to address these challenges. …”
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High Content Analysis of Human Pluripotent Stem Cell Derived Hepatocytes Reveals Drug Induced Steatosis and Phospholipidosis by Arvind Pradip, Daniella Steel, Susanna Jacobsson, Gustav Holmgren, Magnus Ingelman-Sundberg, Peter Sartipy, Petter Björquist, Inger Johansson, Josefina Edsbagge

“…Recent advances in differentiating human induced pluripotent stem cells (hiPSCs) into pure cultures of hepatocyte-like cells expressing functional drug metabolizing enzymes open up possibilities for novel, more relevant human cell based toxicity models. …”
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Automating skin cancer screening: a deep learning by Nada M. Rashad, Noha MM. Abdelnapi, Ahmed F. Seddik, M. A. Sayedelahl

“…On the ISIC dataset, an analysis has been done. This study offers a novel approach to early skin cancer diagnosis based on image processing. …”
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SOX5-Null Heterozygous Mutation in a Family with Adult-Onset Hyperkinesia and Behavioral Abnormalities by Michael Zech, Katharina Poustka, Sylvia Boesch, Riccardo Berutti, Tim M. Strom, Wolfgang Grisold, Werner Poewe, Juliane Winkelmann

“…In contrast to SOX5-involving deletions, examples of pathogenic SOX5 small coding variations are sparse in the literature and have been described only in singular cases with phenotypic abnormalities akin to those seen in the SOX5 microdeletion syndrome. Here a novel SOX5 loss-of-function point mutation, c.13C>T (p.Arg5X), is reported, identified in the course of exome sequencing applied to the diagnosis of an unexplained adult-onset motor disorder. …”
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