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10161
Adipose Tissue Remodeling as Homeostatic Inflammation
Published 2011-01-01“…Understanding the molecular mechanism underlying homeostatic inflammation may lead to the identification of novel therapeutic strategies to prevent or treat obesity-related complications.…”
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10162
Dynamic displacement measurement of a wind turbine tower using accelerometers: tilt error compensation and validation
Published 2025-01-01“…The standard solution is to explicitly measure the tilt angle, which requires an additional sensor for each measurement point and is not applicable for already recorded measurements without tilt information. Therefore, a novel tilt error compensation method is presented by using the static bending line. …”
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10163
Soliton solutions of the (2 + 1)-dimensional Jaulent-Miodek evolution equation via effective analytical techniques
Published 2025-01-01“…Furthermore, the solutions presented in this study are novel, representing contributions that have not been previously reported in the literature.…”
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10164
Antidiabetic Activity of Benzopyrone Analogues in Nicotinamide-Streptozotocin Induced Type 2 Diabetes in Rats
Published 2014-01-01“…Benzopyrones are proven antidiabetic drug candidate in diabetic drug discovery. In this view novel synthetic benzopyrone analogues were selected for testing in experimental diabetes. …”
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10165
Micro-Expression Recognition Using Convolutional Variational Attention Transformer (ConVAT) With Multihead Attention Mechanism
Published 2025-01-01“…To address these limitations, we propose the Convolutional Variational Attention Transformer (ConVAT), a novel model that leverages a multi-head attention mechanism integrated with convolutional networks, optimized specifically for detailed micro-expression analysis. …”
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10166
Exploring TNFR1: from discovery to targeted therapy development
Published 2025-01-01“…In conclusion, this study contributes novel insights into the biological functions of TNFR1 and presents potential therapeutic strategies for clinical application, thereby having substantial scientific and clinical significance.…”
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10167
Intercellular communication is crucial in the regulation of healthy aging via exosomes
Published 2025-02-01“…Exosomes may represent a novel approach for the treatment and diagnosis of aging-related conditions in animals. …”
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10168
A Unified Bayesian Model for Generalized Community Detection in Attribute Networks
Published 2020-01-01“…In this paper, we propose a novel unified Bayesian generative model to detect generalized communities and provide semantic descriptions simultaneously by combining network topology and node attributes. …”
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10169
Identification and validation of a prognostic risk model based on radiosensitivity-related genes in nasopharyngeal carcinoma
Published 2025-02-01“…Conclusions: This study established a novel radiosensitivity-related prognostic model, offering insights into NPC prognosis and radiotherapy resistance mechanisms.…”
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10170
Serum Ischemia Modified Albumin Levels in Infertile Couples Underwent in Vitro Fertilization
Published 2015-04-01“… OBJECTIVE: Ischemia-modified albumin (IMA) is a novel biomarker for diagnosis of distinct disease states including infectious diseases, coronary atherosclerotic disease, hypoxic fetal distress and diabetes mellitus. …”
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10171
The Impact of Oxford Nanopore Technologies Based Methodologies on the Genome Sequencing and Assembly of Romanian Strains of <i>Drosophila suzukii</i>
Published 2024-12-01“…Results: We demonstrate that the sup-basecalling model significantly improved the read quality and that adding a relatively small collection of reads had a significant positive impact over the assembly quality. The novel dScaff bioinformatics prototype tool allowed us to perform sequence-level quality tests, as well as to represent assembly selections and display both the contig redundancy and the repeats-enriched genomic sub-sequences. …”
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10172
Early Diagnosis of Alzheimer’s Disease Using Adaptive Neuro K-Means Clustering Technique
Published 2025-01-01“…This study proposes a novel framework for early AD diagnosis using T1-weighted Magnetic Resonance Imaging (MRI). …”
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10173
Thermo-mechanical and material flow characteristics of tool sequencing dynamics in refill FSSW of thin alclad AA7075-T6 sheets: Numerical analysis using meshless smoothed-particle...
Published 2025-06-01“…To overcome this problem, a novel tool sequencing variant of RFSSW, the pin plunging reinforced RFSSW (PPRSP-RFSSW), is proposed. …”
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10174
Electron‐Lattice Synergistic Coordination for Boosting the Electro‐Optic Response of the Crystal
Published 2025-01-01“…Here, an electron‐lattice synergistic coordination strategy is proposed for boosting the E‐O response, and with the langasite as the subject, a novel crystal La3Zr0.5Ga5Si0.5O14 (LZGS) is designed. …”
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10175
Initial Development and Validation of a Transition Readiness Scale for Adolescents with Inflammatory Bowel Disease
Published 2019-01-01“…Conclusion. Validation of a novel TR measurement for adolescents with IBD demonstrated a good correlation between patients and parents. …”
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10176
Endothelial cells under disturbed flow release extracellular vesicles to promote inflammatory polarization of macrophages and accelerate atherosclerosis
Published 2025-01-01“…Conclusions Taken together, targeting the MAPK signaling pathway holds potential as a novel therapeutic strategy for inhibiting the secretion of EC-derived EVs and mitigating the inflammatory polarization of macrophages, ultimately ameliorating the progression of atherosclerosis. …”
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10177
Miniaturized High-Isolation Dual-Frequency Orthogonally Polarized Patch Antenna Using Compact Electromagnetic Bandgap Filters
Published 2014-01-01“…The high isolation is achieved by embedding two novel EBG filters underneath two feed lines to reject the incoming signal from the opposite line. …”
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10178
PPARγ and the Innate Immune System Mediate the Resolution of Inflammation
Published 2015-01-01“…These effects contribute towards the attenuation of multiple disease states, including COPD, colitis, Alzheimer’s disease, and obesity in animal models. Finally, novel specialized proresolving mediators—eicosanoids with critical roles in resolution—may act through PPARγ modulation to promote resolution, providing another exciting area of therapeutic potential for this receptor.…”
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10179
Tumor Microenvironment‐Responsive Nanoparticles Enhance IDO1 Blockade Immunotherapy by Remodeling Metabolic Immunosuppression
Published 2025-02-01“…This study highlights a novel nano‐platform that simultaneously improves metabolism and enhances ICB efficacy to achieve a new and efficient antitumor strategy.…”
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10180
Synthesis of an Acrylamide Copolymer Containing Nano-SiO2 by Ex Situ Cu(0)-Mediated SET-LRP
Published 2019-01-01“…We report herein the synthesis of a novel star-shaped copolymer containing nano-SiO2 by single-electron transfer living radical polymerization (SET-LRP) in aqueous solution. …”
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