Students Participating as Ambassadors for Research in Kentucky (SPARK): A health equity undergraduate research training program by Ariel A. Arthur, Rebecca L. deLacerda Allen, Fidelis Y. Sesenu, Maxwell A. Groznik, Carrie B. Oser, Justin X. Moore, Jessica R. Thompson, Alexis N. James, Madeline N. Dunfee, Philip A. Kern, Nancy E. Schoenberg

“…The Students Participating as Ambassadors for Research in Kentucky (SPARK) program provides novel health equity research training and targeted mentorship for undergraduates, particularly those from groups underrepresented in the biomedical and behavioral research and workforce. …”
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Physalis peruviana calyces extract ameliorate oxidative stress, inflammation, and immune loss in rats-exposed to hexaflumuron by Mona M. Hashem, Eman I. Hassanen, Neven H. Hassan, Marwa A. Ibrahim, Marwa Y. Issa, Mohamed A. Farag, Sherif A. Hamdy

“…Conclusions This study provides novel insights into the potential of P. peruviana L. calyces ethanolic extract as a natural agent to counteract the harmful effects of HFM exposure. …”
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Deficient Purposeful Use of Forepaws in Female Mice Modelling Rett Syndrome by Bianca De Filippis, Mattia Musto, Luisa Altabella, Emilia Romano, Rossella Canese, Giovanni Laviola

“…Present results confirm behavioural and brain alterations previously reported in MeCP2-308 males and identify novel endpoints on which the efficacy of innovative therapeutic strategies for RTT may be tested.…”
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Q-learning global path planning for UAV navigation with pondered priorities by Kevin B. de Carvalho, Hiago de O.B. Batista, Leonardo A. Fagundes-Junior, Iure Rosa L. de Oliveira, Alexandre S. Brandão

“…This study introduces a novel approach to offline path planning in static environments, utilizing Q-learning as its foundation. …”
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Microwave-assisted synthesis and swelling behavior of poly lactic acid (PLA) grafted Cordia dichotoma gum-based hydrogels by Jyoti Sinha, Abubakar Hamisu Mijinyawa, Faisal Islam Chowdhury, Muhd Zu Azhan Yahya, Pramod Kumar Singh, Geeta Durga

“…The swelling of CDG-g-PLA in water was measured and found to be significantly lower than CDG, making them novel candidates for drug-delivery and sustainable food packaging applications.…”
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MacSyFinder v2: Improved modelling and search engine to identify molecular systems in genomes by Néron, Bertrand, Denise, Rémi, Coluzzi, Charles, Touchon, Marie, Rocha, Eduardo P.C., Abby, Sophie S.

“…We also introduce the novel macsydata companion tool that enables the easy installation and broad distribution of the models developed for MacSyFinder (macsy-models) from GitHub repositories. …”
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Alpha synuclein and inflammaging by Geneviève L. Putnam, Robert W. Maitta

“…While the pathological role of α-synuclein (α-syn) in PD has been well described, novel evidence may suggest that α-syn interacts with inflammasomes in response to aging. …”
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A new approach to synthesize nano-yttrium boride particle through metallothermic reduction process by Sadhasivam M., Berchmans L.J., Meenashisundaram G.K., Mehana Usmaniya U., Sankaranarayanan S.R., Kumaresh Babu S.P.

“…In the present study, a novel attempt is made to synthesize yttrium boride (YB4) nano-sized powders through metallothermic reduction method. …”
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Organ-Preserving Surgery for Penile Carcinoma by Francisco E. Martins, Raul N. Rodrigues, Tomé M. Lopes

“…Some articles reported novel techniques of less-mutilating surgery involving different forms of glans reconstruction with the use of flaps or grafts. …”
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Priming Adipose-Derived Mesenchymal Stem Cells with Hyaluronan Alters Growth Kinetics and Increases Attachment to Articular Cartilage by Peter Succar, Michael Medynskyj, Edmond J. Breen, Tony Batterham, Mark P. Molloy, Benjamin R. Herbert

“…Using a range of hyaluronan concentrations, we measured MSC adherence and proliferation on culture plastic surfaces and a novel cartilage-adhesion assay. We employed time-course and dispersion imaging to assess MSC binding to cartilage. …”
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Graphene-Based, Flexible, Wearable Piezoresistive Sensors with High Sensitivity for Tiny Pressure Detection by Rui Li, Jiahao Hu, Yalong Li, Yi Huang, Lin Wang, Mohan Huang, Zhikun Wang, Junlang Chen, Yan Fan, Liang Chen

“…Here, we present a piezoresistive sensor with a novel microstructure that combines insulating and conductive properties. …”
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Inhibition of transcriptional regulation of detoxification genes contributes to insecticide resistance management in Spodoptera exigua by Bo Hu, Yuping Deng, Tao Lu, Miaomiao Ren, Kuitun Liu, Cong Rao, Hailiang Guo, Jianya Su

“…Altogether, our results demonstrate that reduced expression of detoxification genes resulting from suppression of transcriptional regulation of these genes contributes to controlling insecticide resistance, which provides a very novel and high-efficiency green resistance management strategy.…”
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Additively manufactured biodegradable Zn metamaterials with tunable Poisson’s ratio and enhanced mechanical properties by Yixuan Shi, Jiaqi Gao, Xuan Li, Zui Tao, Chengcong Huang, Shangyan Zhao, Yuzhi Wu, Youwen Yang, Yabin Yang, Yageng Li, Lu-Ning Wang

“…This study introduces a novel reinforced unit cell, optimised in 3D to retain NPR characteristics while significantly enhancing scaffold strength. …”
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Relationship between the CUBN and the MIA3 gene copy number variation and growth traits in different cattle breeds by Yue Han, Jiwei Liu, Congcong Zhang, Ming Sun, Xuanyu Li, Hongliang Liu, Shengnan Li, Yongchao Zhu, Ruidong Li, Xiaotong Luo, Yumin Zhao, Jian Wu

“…In conclusion, CUBN CNV is correlated significantly with growth traits in Chinese cattle and is a novel molecular marker that could be exploited in cattle breeding.…”
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Functional Prediction of Hypothetical Proteins from and Validation of the Predicted Models by Using ROC Curve Analysis by Md. Amran Gazi, Sultan Mahmud, Shah Mohammad Fahim, Mohammad Golam Kibria, Parag Palit, Md. Rezaul Islam, Humaira Rashid, Subhasish Das, Mustafa Mahfuz, Tahmeed Ahmeed

“…Our comprehensive analysis will help to gain greater understanding for the development of many novel potential therapeutic interventions to defeat Shigella infection.…”
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A Theoretical Study on the Efficacy and Mechanism of Combined YAP-1 and PARP-1 Inhibitors in the Treatment of Glioblastoma Multiforme Using Peruvian Maca <i>Lepidium meyenii</i> by Albert Gabriel Turpo-Peqqueña, Sebastian Luna-Prado, Renato Javier Valencia-Arce, Fabio Leonardo Del-Carpio-Carrazco, Badhin Gómez

“…This study explored the inhibitory potential of natural compounds from <i>Lepidium meyenii</i> (Peruvian Maca) on the YAP-1 and PARP-1 protein systems to develop novel therapeutic strategies for GBM. By molecular dynamics simulations, we identified N-(3-Methoxybenzyl)-(9Z,12Z,15Z)- octadecatrienamide (DK5) as the most promising natural inhibitor for PARP-1 and stearic acid (GK4) for YAP-1. …”
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Analysis of Chaotic Features in Dry Gas Seal Friction State Using Acoustic Emission by Shuai Zhang, Xuexing Ding, Jinlin Chen, Shipeng Wang, Lanxia Zhang

“…This approach provides a novel framework for utilizing AE signals to evaluate the friction states of dry gas seals.…”
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Global transcriptional modulation and nutritional status of soybean plants following foliar application of zinc borate as a suspension concentrate fertilizer by Eloisa Vendemiatti, Rafael Oliveira Moreira, Gabriel Lasmar dos Reis, Inty Omar Hernandez-De Lira, Eugenia Peña-Yewtukhiw, Franz Walter Rieger Hippler, Luis Omar Torres-Dorante, Kiran Pavuluri, Alex Valentine, Vitor L. Nascimento, Vagner Augusto Benedito

“…Furthermore, a gene lacking functional annotation (Glyma.03G180300) emerged as a novel potential marker of B status. Two genes (Glyma.16G118000, Glyma.16G199000) were consistently induced by Zn availability, highlighting their potential as biomarkers for assessing its status in soybean plants. …”
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Effect of ultrasonic modification on the protective activity of Flammulina velutipes polysaccharide to prevent ethanol-induced injury on GES-1 cells by Jinrong Xiao, Xin Chen, Jingsi Zhang, Yifan Wang, Lei Zhong, Qiping Zhan, Qiuhui Hu, Liyan Zhao

“…The ultrasonic modification might be an effective way to develop novel F. velutipes polysaccharides that could effectively resist the gastric injury caused by excessive alcohol consumption.…”
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Intrapericardial injection of hydrogels with ASC and their secretome to treat dilated cardiomyopathies by Tácia Tavares Aquinas Liguori, Gabriel Romero Liguori, Viktor Sinkunas, Cristiano Jesus Correia, Raphael dos Santos Coutinho e Silva, Fernando Luiz Zanoni, Vera Demarchi Aiello, Martin Conrad Harmsen, Luiz Felipe Pinho Moreira

“…The intrapericardial injection of dECM hydrogels loaded with ASC and their secretome warrants a novel therapeutic modality to improve ventricular hemodynamics and reduce cardiac remodeling in DOX-IC.…”
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