Proteomic profiling of the local and systemic immune response to pediatric respiratory viral infections by Emily Lydon, Christina M. Osborne, Brandie D. Wagner, Lilliam Ambroggio, J. Kirk Harris, Ron Reeder, Todd C. Carpenter, Aline B. Maddux, Matthew K. Leroue, Nadir Yehya, Joseph L. DeRisi, Mark W. Hall, Athena F. Zuppa, Joseph Carcillo, Kathleen Meert, Anil Sapru, Murray M. Pollack, Patrick McQuillen, Daniel A. Notterman, Charles R. Langelier, Peter M. Mourani

“…To address this gap, gain insights into vLRTI pathophysiology, and test a novel diagnostic approach, we assayed 1,305 proteins in tracheal aspirate (TA) and plasma from 62 critically ill children using SomaScan. …”
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Exploring Future Pandemic Preparedness Through the Development of Preventive Vaccine Platforms and the Key Roles of International Organizations in a Global Health Crisis by Jihee Jeon, Eunyoung Kim

“…It should include a balanced investment in both novel technologies such as mRNA and viral vector-based vaccines and traditional platforms. …”
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Benefits of a second tandem flight phase between two successive satellite altimetry missions for assessing instrumental stability by M. Ablain, N. Lalau, B. Meyssignac, R. Fraudeau, A. Barnoud, G. Dibarboure, A. Egido, C. Donlon

“…This study aims to propose a novel cross-validation method with a better ability to assess the instrumental stability (i.e., instrumental drifts in the global mean sea level trends). …”
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Construction of feature selection and efficacy prediction model for transformation therapy of locally advanced pancreatic cancer based on CT, 18F-FDG PET/CT, DNA mutation, and CA19... by Liang Qi, Xiang Li, Jiayao Ni, Yali Du, Qing Gu, Baorui Liu, Jian He, Juan Du

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Cross-Gendering the Racial Memory by Marlon B. Ross

“…When Ernest Gaines chooses a woman as the individual subject for collective memorialization and the ideal medium of racial memory in his 1971 novel, The Autobiography of Miss Jane Pittman, he participates in a significant but overlooked genre of black masculine discourse, the composition of black authorship as historical/national authority through the voice and viewpoint of a female protagonist. …”
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Research on expansion joint for high-speed railway long-span bridges in China by Hui Guo, Jinzhou Jiang, Suoting Hu, Chun Yang, Qiqi Xiang, Kou Luo, Xinxin Zhao, Bing Li, Ziquan Yan, Liubin Niu, Jianye Zhao

“…The performance of the novel BEJ design thus derived was then verified via theoretical analysis under different scenarios, full-scale model testing, and field testing and commissioning. …”
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Simultaneous Recovery of Hydrogen and Chlorine from Industrial Waste Dilute Hydrochloric Acid by N. Paidimarri, U. Virendra, S. Vedantam

“…The present motive of this work is to develop a novel electrolysis process which in contrast to traditional processes effectively recovers both hydrogen and chlorine from dilute HCl. …”
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Performance and Energy Consumption Analysis for UWSNs with Priority Scheduling Based on Access Probability and Wakeup Threshold by Ning Li, Zhiyu Xiang, Liang Feng, Zhiqiang Gao, Jiaqi Liu, Haitao Gu

“…To address these challenges, a novel mixed packet forwarding strategy is developed, which incorporates a wakeup threshold and a dynamically adjusted access probability for the cluster head (CH). …”
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De Novo Assembly of the Pea (Pisum sativum L.) Nodule Transcriptome by Vladimir A. Zhukov, Alexander I. Zhernakov, Olga A. Kulaeva, Nikita I. Ershov, Alexey Y. Borisov, Igor A. Tikhonovich

“…Of these, 581 sequences were found to possess full CDSs and could thus be considered as novel nodule-specific transcripts of pea. The information about pea nodule-specific gene sequences can be applied for gene-based markers creation, polymorphism studies, and real-time PCR.…”
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Predictive Trajectory-Based Mobile Data Gathering Scheme for Wireless Sensor Networks by Fan Chao, Zhiqin He, Renkuan Feng, Xiao Wang, Xiangping Chen, Changqi Li, Ying Yang

“…In these applications, the tour planning of MS is a key to guarantee the network performance. In this paper, a novel strategy is proposed to reduce the latency of mobile data gathering in a WSN while the routing strategies and tour planning of MS are jointly optimized. …”
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Investigating new drugs from marine seaweed metabolites for cervical cancer therapy by molecular dynamic modeling approach by Sk Injamamul Islam, Sheikh Sunzid Ahmed, Sarower Mahfuj, Gunjan Das, Md. Mohaimenul Islam Tareq, Mazen Almehmadi, Mamdouh Allahyani, Naif Alsiwiehri, Partha Biswas, Md. Nazmul Hasan, Foysal Ahammad

“…The high costs and side effects of standard treatments and the limited efficacy of HPV vaccination have led to a quest for novel, cost-effective cervical cancer treatments, particularly in middle- and low-income countries. …”
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Neurological damages in COVID‐19 patients: Mechanisms and preventive interventions by Sibani Sarkar, Subhajit Karmakar, Malini Basu, Pratyasha Ghosh, Mrinal K Ghosh

“…Abstract Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), a novel coronavirus, causes coronavirus disease 2019 (COVID‐19) which led to neurological damage and increased mortality worldwide in its second and third waves. …”
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Vitamin D Receptor, Retinoid X Receptor, Ki-67, Survivin, and Ezrin Expression in Canine Osteosarcoma by John Davies, Heather Heeb, Rama Garimella, Kimberly Templeton, David Pinson, Ossama Tawfik

“…Vitamin D has been postulated as a novel therapeutic option for many malignancies. Upon activation, vitamin D receptors (VDRs) combine with retinoid receptor (RXR) forming a heterodimer initiating a cascade of events. …”
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The Palatability of Lopinavir and Ritonavir Delivered by an Innovative Freeze-Dried Fast-Dissolving Tablet Formulation by David W. Pittman, Alexandra M. Brantly, Alexandra L. Drobonick, Hannah T. King, Daniel C. Mesta, Caroline G. Richards, Manjari Lal, Manshun Lai

“…The averseness of the FDT+ was associated with the presence of LPV/r and not the FDT− formulation itself. The novel FDT formulation appears to be a palatable delivery mechanism for oral antiretroviral pharmaceuticals especially when mixed with baby foodstuffs.…”
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Heterobimetallic Zn2+/Co2+ Monocarboxylates as Precursors for ZnO Microparticles Doped with Cobalt and its Photocatalytic Activity in Methyl Orange Oxidation by Hélder Inocêncio Ferreira Correa, Ralf Ricardo Ramalho Jr, Adhimar Flávio Oliveira, Fabio da Silva Lisboa

“…In this work, zinc oxide microparticles doped with cobalt were prepared from two novel layered heterobimetallic monocarboxylates as precursors to obtain uniform shape and size oxide particles, aiming for a photocatalytic removal of methyl orange. …”
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Development and validation of a predictive model for lymph node metastases in peripheral non-small cell lung cancer with a tumor diameter ≤ 2.0 cm and a consolidation-to-tumor rati... by Dongyu Li, Dongyu Li, Shaolei Li, Hongbing Zhang, Chunqiu Xia, Xiaoyong Nan, Hongyu Liu, Jun Chen, Jun Chen

“…The model showed good calibration (Hosmer–Lemeshow (HL) P value = 0.680) with an area under the receiver operating characteristic curve (AUC) = 0.890 (95% confidence interval (CI): 0.808–0.972) in the validation cohort.ConclusionsWe developed and validated a novel and effective model that predicted the probability of LNM for individual patients with peripheral NSCLC who had a tumor diameter ≤ 2.0 cm and CTR > 0.5. …”
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Reprogramming of Adult Retinal Müller Glial Cells into Human-Induced Pluripotent Stem Cells as an Efficient Source of Retinal Cells by Amélie Slembrouck-Brec, Amélie Rodrigues, Oriane Rabesandratana, Giuliana Gagliardi, Céline Nanteau, Stéphane Fouquet, Gilles Thuret, Sacha Reichman, Gael Orieux, Olivier Goureau

“…This advanced maturation of photoreceptors not only supports the possibility to use 3D retinal organoids for studying photoreceptor development but also offers a novel opportunity for disease modeling, particularly for inherited retinal diseases.…”
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Prevalence and molecular characterization of Enterocytozoon bieneusi in endangered Eld’s deer (Rucervus eldii) in Hainan, China by Yun Zhang, Yun Zhang, Guangxu Ren, Guangxu Ren, Qingqing Lu, Jiaqi Li, Jiaqi Li, Yu Qiang, Youyou Li, Xiuyi Lai, Yuan Wang, Xingyue Yu, Sheng Lei, Yu Li, Yunxing Chang, Xianrong Liu, Xuning Qi, Zhi Xie, Tingting Li, Jiang Du, Rui Duan, Xinyu Chang, Hesheng Wang, Hesheng Wang, Gang Lu, Gang Lu

“…Seven ITS genotypes were identified, including five known genotypes: D (n = 19), Peru11 (n = 10), EbpC (n = 5), Peru8 (n = 1) and Type IV (n = 1), and two novel genotypes: HNED-I and HNED-II (one each). Genotypes Peru8 and Peru11 were firstly identified in cervids. …”
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Gene Expression Differences Predict Treatment Outcome of Merkel Cell Carcinoma Patients by Loren Masterson, Bryan J. Thibodeau, Laura E. Fortier, Timothy J. Geddes, Barbara L. Pruetz, Rajwant Malhotra, Richard Keidan, George D. Wilson

“…Immunohistochemistry further established that keratin 20 was overexpressed in the poor prognosis tumors. In addition, novel genes of interest such as phospholipase A2 group X, kinesin family member 3A, tumor protein D52, mucin 1, and KIT were upregulated in specimens from patients with poor prognosis. …”
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The Characterization of L-Asparaginase with Low L-Glutaminase Activity Produced by the Marine <i>Pseudomonas</i> sp. Strain GH-W2b by Woon-Jong Yu, Ha Young Lee, Yong Min Kwon, Seung Seob Bae, Grace Choi, Hyun-Ju Hwang, Dawoon Chung

“…Therefore, identifying novel sources of ASNase is critical. In the present study, we identified an asparaginase-producing marine bacterial strain, GH-W2b, as a <i>Pseudomonas</i> species. …”
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