A Novel Discrete Global-Best Harmony Search Algorithm for Solving 0-1 Knapsack Problems by Wan-li Xiang, Mei-qing An, Yin-zhen Li, Rui-chun He, Jing-fang Zhang

“…In order to better solve discrete 0-1 knapsack problems, a novel global-best harmony search algorithm with binary coding, called DGHS, is proposed. …”
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Noncoding RNA profiling in omentum adipose tissue from obese patients and the identification of novel metabolic biomarkers by Yongjiao Zhang, Yongjiao Zhang, Ao Chen, Ao Chen, Sumei Lu, Dong Liu, Xiaolei Xuan, Xiaofei Lei, Mingwei Zhong, Fei Gao

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APBIO: bioactive profiling of air pollutants through inferred bioactivity signatures and prediction of novel target interactions by Eva Viesi, Ugo Perricone, Patrick Aloy, Rosalba Giugno

“…The proposed chemogenomic methodology enables the prediction of novel CTIs for known or similar compounds and targets through well-established and efficient ML models, deepening our insight into the molecular interactions and mechanisms that may have a deleterious impact on human biological systems.…”
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Thioxopyrimidine in Heterocyclic Synthesis I: Synthesis of Some Novel 6-(Heteroatom-substituted)-(thio)pyrimidine Derivatives by Yuh-Wen Ho, Maw Cherng Suen

“…A series of novel N-cycloalkanes, morpholine, piperazines, pyrazole, pyrimidine, benzimidazolo[1,2-a]pyrimidine, 1,2,3,4-tetrazolo[1,5-a]pyrimidine, azopyrazolo[1,5- a]pyrimidine, pyrimido[4', 5':3,4]pyrazolo[1,5-a]pyrimidines and pyridine derivatives incorporating a 5-cyano-4-methyl-2-phenyl-(thio)pyrimidine moiety were obtained by the intramolecular cyclization of 6-methylthio-pyrimidine, 6-(benzoylmethyl)thio- pyrimidine and 2-[(5-cyano-4-methyl-2-phenylpyrimidin-6-yl)thio]-3-dimethyl- amino-1-phenyl-prop-2-en-1-one with appropriate amines and enaminone compounds, respectively. …”
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Swarm Confrontation Algorithm for UGV Swarm with Quantity Advantage by a Novel MSRM-MAPOCA Training Method by Huanli Gao, Chongming Zhao, Xinghe Yu, Shuangfei Ren, He Cai

“…To address the issue of sparse reward which would result in inefficient learning and poor training performance, a novel macro states reward mechanism based on multi-agent posthumous credit assignment (MSRM-MAPOCA) is proposed in this paper, which together with fine-tuned smooth reward design can fully exploit the advantage in quantity and thus leads to outstanding training performance. …”
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Shared genetics between breast cancer and predisposing diseases identifies novel breast cancer treatment candidates by Panagiotis N. Lalagkas, Rachel D. Melamed

“…The result provides 59 novel candidate drugs alongside biological insights supporting each recommendation.…”
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Isolation and identification of novel casein-derived bioactive peptides and potential functions in fermented casein with Lactobacillus helveticus by Mengzhu Fan, Tingting Guo, Wanru Li, Jing Chen, Fushuo Li, Chao Wang, Yi Shi, David Xi-an Li, Shaohui Zhang

“…Thirteen peptides with the potential of some biological activities are obtained, which were described in previous studies. A total of 47 novel peptides of 5 to 26 amino acids that were not disclosed were obtained. …”
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A Room with Two Views: An Insight into the 1985 and 2007 Film Adaptations of E. M. Forster’s Novel by Elena Raicu

“…Considered to be one of the best English-language novels of the last century, A Room with a View by E. …”
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Sonic Hedgehog Signaling Drives Proliferation of Synoviocytes in Rheumatoid Arthritis: A Possible Novel Therapeutic Target by Mingxia Wang, Shangling Zhu, Weixiang Peng, Qiuxia Li, Zhaoxia Li, Minqi Luo, Xiaoxue Feng, Zhuofeng Lin, Jianlin Huang

“…It may therefore be a novel therapeutic target in RA.…”
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TUBA1B as a novel prognostic biomarker correlated with immunosuppressive tumor microenvironment and immunotherapy response by Juntao Qi, Juntao Qi, Mingming Zhou, Na Yang, Huiyun Ma, Min He, Gujie Wu, Chang Ge, Liuyin Jin, Lin Cheng, Wei Liao, Hefei Ren, Caiyun Lei

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Long Noncoding RNAs in Digestive System Malignancies: A Novel Class of Cancer Biomarkers and Therapeutic Targets? by Athina Kladi-Skandali, Kleita Michaelidou, Andreas Scorilas, Konstantinos Mavridis

“…The unconventional role of lncRNAs in gene expression regulation and their broad implication in oncogenic and tumor suppressive pathways have introduced lncRNAs as novel biological tumor markers. The most prominent example of lncRNAs application in routine clinical practice is PCA3, a FDA-approved biomarker for prostate cancer. …”
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Communication: Synthesis of a Novel Triphenyltin(IV) Derivative of 2- Mercaptonicotinic Acid with Potent Cytotoxicity in vitro by Marianna N. Xanthopoulou, Sotiris K. Hadjikakou, Nick Hadjiliadis, Markus Schürmann, Klaus Jurkschat, Jayne Binolis, Spyros Karkabounas, Konstantinos Charalabopoulos

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Synthesis of Symmetrical and Asymmetrical Azines Encompassing Naphtho[2,1-b]furan by a Novel Approach by K. Veena, M. Ramaiah, G. K. Vanita, T. S. Avinash, V. P. Vaidya

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Intralesional Spesolimab: A Novel and Effective Approach for Palmoplantar Pustulosis Treatment – A Case Report by Wang SN, Lu YZ, Zhao Y, Cao W, Zhang RL

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A Novel Cellular Handset Design for an Enhanced Antenna Performance and a Reduced SAR in the Human Head by Salah I. Al-Mously, Marai M. Abousetta

“…This paper presents a novel cellular handset design with a bottom-mounted short loaded-whip antenna. …”
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Persistent Bacteremia from Pseudomonas aeruginosa with In Vitro Resistance to the Novel Antibiotics Ceftolozane-Tazobactam and Ceftazidime-Avibactam by Louie Mar Gangcuangco, Patricia Clark, Cynthia Stewart, Goran Miljkovic, Zane K. Saul

“…Emerging resistance mechanisms to these novel antibiotics need to be further investigated.…”
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Novel loci for triglyceride/HDL-C ratio longitudinal change among subjects without T2D by Lihua Wang, Siyu Wang, Jason A. Anema, Vaha A. Moghaddam, Yanli Lu, Shiow Lin, E. Warwick Daw, Allison L. Kuipers, Iva Miljkovic, Michael Brent, Gary J. Patti, Bharat Thygarajan, Joseph M. Zmuda, Michael A. Province, Ping An

“…Our findings provided novel insights into the molecular regulation of insulin resistance.…”
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A Novel Method for Extracting Maximum Kurtosis Component and Its Applications in Rolling Bearing Fault Diagnosis by Yonggang Xu, Zeyu Fan, Kun Zhang, Chaoyong Ma

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WWTR1-AS1 LncRNA as a Novel Potential Diagnostic and Prognostic Biomarker in Breast Cancer by Mohadese Safabakhsh, Sohrab Boozarpour, Kamran Ghaedi, Mina Lashkarboloki, Shaaban Ghalandarayeshi

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Streptomyces griseiviridis sp. nov., a Novel “Modern Actinobacteria” isolated from Malaysia Mangrove Soil by Jodi Woan Fei Law, Loh Teng-Hern Tan, Vengadesh Letchumanan, Kar-Wai Hong, Hooi-Leng Ser, Bey-Hing Goh, Nurul Syakima Ab Mutalib, Kok-Gan Chan, Learn-Han Lee

“… A novel strain, Streptomyces griseiviridis MUM 136JT was recovered from a mangrove forest soil in Malaysia. …”
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