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4221
Fungal Infections in Kidney Transplant Recipients: A Comprehensive Narrative Review
Published 2025-01-01“…Future research is needed to optimize diagnostic tools, identify novel antifungal agents, and develop better prophylactic strategies for high-risk transplant recipients.…”
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4222
Discovery of Antimalarial Drugs from Streptomycetes Metabolites Using a Metabolomic Approach
Published 2017-01-01“…Metabolomics approach in finding novel therapeutics agent for malaria offers dereplication step in screening phase to shorten the process. …”
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4223
Intra- and Extra-Articular Deformity of Lower Limb: Tibial Condylar Valgus Osteotomy (TCVO) and Distal Tibial Oblique Osteotomy (DTOO) for Reconstruction of Joint Congruency
Published 2019-01-01“…Distal tibial oblique osteotomy (DTOO) is a novel surgery to improve the bony congruency of the ankle OA. …”
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4224
Learning through “Research Cognitive Theory”: A new framework for developing 21st century research skills in secondary school students
Published 2025-01-01“…This study introduces a novel framework for High School Research Cognitive Learning Program (HSRCLP), focused on developing 21st century research skills (including research behavior, scientific identity, and values for the scientific community) among high school students. …”
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4225
The research progress of biologics in elderly-onset rheumatoid arthritis (EORA)
Published 2025-01-01“…Future research should focus on validating the long-term safety of novel therapies and refining individualized treatment strategies to enhance patient outcomes and quality of life.…”
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4226
Rainbow: An Operating System for Software-Hardware Multitasking on Dynamically Partially Reconfigurable FPGAs
Published 2013-01-01“…Finally, we present a novel model and implementation of a channel-based intertask communication and synchronization suitable for software-hardware multitasking with preemptable and clock-scalable hardware tasks. …”
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4227
Genome-Wide Association Study towards Genomic Predictive Power for High Production and Quality of Milk in American Alpine Goats
Published 2020-01-01“…The outcome of this study supports elucidation of novel genes that are important for livestock species in association to key phenotypic traits. …”
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4228
Personalized Federated Learning for Heterogeneous Residential Load Forecasting
Published 2023-12-01“…Further, we introduce a novel differential privacy (DP) algorithm in the proposed system to provide an additional privacy guarantee. …”
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4229
Design of a new class of broad-spectrum therapeutics targeted to drug-resistant bacteria
Published 2024-12-01“…Key policy highlights Development of a novel class of antimicrobial compounds Drug screen against a WHO ‘high’ priority drug-resistant pathogen that poses the greatest threat to human health (methicillin-resistant Staphylococcus aureus) Drug screen against a surrogate for Mycobacterium tuberculosis, one of the leading causes of mortality worldwide.…”
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4230
High SERS performance of functionalized carbon dots in the detection of dye contaminants
Published 2025-02-01“…The functional nanocomposite is novel and challenging to construct and implement through surface enhanced Raman scattering (SERS) strategy to reveal the contributions in application. …”
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4231
Unusual Localization of Clostridium Difficile Infection in an Isolated Segment of the Descending Colon in a Critical Care Patient
Published 2012-01-01“…Here, we present a case of a 48-year-old man with Clostridium difficile colitis of an isolated segment in the descending colon treated by a novel catheter intraluminal antibiotic irrigation. …”
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4232
Numerical Analysis of the Width Design of a Protective Pillar in High-Stress Roadway: A Case Study
Published 2021-01-01“…The width design of protective pillars is an important factor affecting the stability of high-stress roadways. In this study, a novel numerical modeling approach was developed to investigate the relationship between protective pillar width and roadway stability. …”
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4233
Evaluation for Retinal Therapy for RPE65 Variation Assessed in hiPSC Retinal Pigment Epithelial Cells
Published 2021-01-01“…Human induced pluripotent stem cells (hiPSCs) generated from patients and the derivative retinal cells enable the investigation of pathological and novel variants in relevant cell populations. Biallelic pathogenic variants in RPE65 cause early-onset severe retinal dystrophy (EOSRD) or Leber congenital amaurosis (LCA). …”
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4234
Charge doping into spin minority states mediates doubling of T C in ferromagnetic CrGeTe3
Published 2025-01-01“…Abstract The recent discovery of the persistence of long-range magnetic order when van der Waals magnets are thinned towards monolayers provides a tunable platform for engineering of novel magnetic structures and devices. Here, we study the evolution of the electronic structure of CrGeTe3 as a function of surface electron doping. …”
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4235
Dorsal venous complex ligation‐free and parietal endopelvic fascia preserving in laparoscopic radical prostatectomy: A prospective study of single centre
Published 2024-11-01“…Abstract Objectives This study aims to describe a novel dorsal venous complex (DVC) ligation‐free and parietal endopelvic fascia preserving technique for laparoscopic radical prostatectomy and to evaluate its post‐operative outcomes. …”
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4236
Current achievements in modifying crop genes using CRISPR/Cas system
Published 2019-02-01“…With the advent of the new genome editing tool of target-specifically customizable endonucleases, a huge variety of novel opportunities have become feasible. The crop improvement is one of the main applications of genome editing in plant science and plant biotechnology. …”
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4237
Determining the Potential Roles of Branched-Chain Amino Acids in the Regulation of Muscle Growth in Common Carp (Cyprinus carpio) Based on Transcriptome and MicroRNA Sequencing
Published 2023-01-01“…A total of 43,414 known and 1,112 novel genes were identified, in addition to 142 known and 654 novel miRNAs targeting 22,008 and 33,824 targets, respectively. …”
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4238
Design of generic vedic ALU using reversible logic
Published 2025-04-01“…Incorporating Vedic reversible logic with vinculum in FPGA design introduces a novel approach leveraging parallelism and pipelining for enhanced efficiency and performance. …”
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4239
GWAS of a soybean breeding collection from South East and South Kazakhstan for resistance to fungal diseases
Published 2018-08-01“…Two QTL both for FUS (chromosomes 13 and 17) and BS (chromosomes 14 and 17) were genetically mapped, including one presumably novel QTL for BS (chromosome 17). Also, five presumably novel QTL for FLS were genetically mapped on chromosomes 2, 7, and 15. …”
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4240
A patient-derived HCC spheroid system to model the tumor microenvironment and treatment response
Published 2025-02-01“…Methods: We established a novel and simple patient-derived multicellular tumor spheroid model based on clinical HCC tumor tissues, processed using enzymatic and mechanical dissociation. …”
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