A two-step method for assessing enhanced value in turnaround, spin-off, and value stocks by Nicolas Pfister, Michael J. Kendzia, Jan-Alexander Posth

“…In this event study, to test for the existence of risk-adjusted excess returns, or alpha, a novel two-step approach is proposed to assess Enhanced Value in single stocks for three different investment approaches: plain value investing, investing in spin-offs, and investing in turnaround companies. …”
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Sealless Production Ultracentrifuge and Its Magnetically Self-Bearing Openable Motors for Purification in Viral Nanotechnology by Emanuel J. Hubmann, Daniel Steinert, Thomas Nussbaumer, Johann W. Kolar

“…This article proposes a novel PUCF type with rotational speed potential towards 100 krpm with a hermetically enclosed process chamber without any rotary seals, i.e. a sealless production ultracentrifuge (SL-PUCF) omitting contamination risk. …”
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Peptide-Based Vaccinology: Experimental and Computational Approaches to Target Hypervariable Viruses through the Fine Characterization of Protective Epitopes Recognized by Monoclon... by Matteo Castelli, Francesca Cappelletti, Roberta Antonia Diotti, Giuseppe Sautto, Elena Criscuolo, Matteo Dal Peraro, Nicola Clementi

“…Defining immunogenic domains of viral proteins capable of eliciting a protective immune response is crucial in the development of novel epitope-based prophylactic strategies. This is particularly important for the selective targeting of conserved regions shared among hypervariable viruses. …”
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Nanotherapeutics for Meningitis: Enhancing Drug Delivery Across the Blood-Brain Barrier by Hitaishi Sharma, Kannan Badri Narayanan, Shampa Ghosh, Krishna Kumar Singh, Prarthana Rehan, Aparajita Dasgupta Amist, Rakesh Bhaskar, Jitendra Kumar Sinha

“…Hence, it is imperative to develop novel approaches that can overcome these constraints and offer efficient therapy for meningitis. …”
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circRNA_101277 Influences Cisplatin Resistance of Colorectal Cancer Cells by Modulating the miR-370/IL-6 Axis by Qing Lv, Qinghua Xia, Anshu Li, Zhiyong Wang

“…The identification of genes associated with CRC chemoresistance would thus be a beneficial approach to identifying novel treatments for this deadly disease. Methods. …”
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Distinguishing classes of neuroactive drugs based on computational physicochemical properties and experimental phenotypic profiling in planarians. by Danielle Ireland, Christina Rabeler, Sagar Rao, Rudy J Richardson, Eva-Maria S Collins

“…Mental illnesses put a tremendous burden on afflicted individuals and society. Identification of novel drugs to treat such conditions is intrinsically challenging due to the complexity of neuropsychiatric diseases and the need for a systems-level understanding that goes beyond single molecule-target interactions. …”
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Molecular Characterization and Antibacterial Potential of Endophytic Fungal Isolates from Selected Mangroves along the Coastline of Kenya by Teresia Nyambura Wacira, Huxley Mae Makonde, Carren Moraa Bosire, Cromwell Mwiti Kibiti

“…Scientists have been striving to find novel bioactive compounds and drugs to overcome these obstacles. …”
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Immunological Responses and Epitope Mapping by Tuberculosis-Associated Antigens within the RD1 Region in Japanese Patients by Hideaki Nagai, Maho Suzukawa, Yumi Sakakibara, Ken Ohta, Pedro A. Reche, Koichi Suzuki, Yoshihiko Hoshino

“…Tuberculosis remains a major global health problem worldwide, and hence there is a need for novel vaccines that better induce cellular-mediated immunity (CMI). …”
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Soft-Label Supervised Meta-Model with Adversarial Samples for Uncertainty Quantification by Kyle Lucke, Aleksandar Vakanski, Min Xian

“…In addition, a novel training framework using adversarial samples is proposed to explore the decision boundary of the base model and mitigate issues related to training datasets with label imbalance. …”
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Study on the Coarsening Behavior of Interphase Precipitates and Random Precipitates in Steel Under the High-Temperature Environment of Fire by Jinghua Cong, Yongzhe Yang, Haibin Zhu, Xueliang Shang, Hongyu Wu, Zhendong Song, Xuemin Wang, Xiangyu Xu

“…This study developed a novel heat treatment protocol to concurrently achieve both interphase precipitation and random precipitation. …”
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Mitigation PFHxA-induced neurotoxicity in Carassius auratus brain cells by selenium-enriched Bacillus subtilis via the BDNF/PI3K/AKT/GSK-3β pathway by Yu-ting Lu, Zheng-yao Guo, Lei Guo, Yu-hua He, Li-ming Liu, Xue Jiao, Yue-hong Li

“…Additionally, our findings establish a novel theoretical framework for using selenium-enriched Bacillus subtilis in environmental toxicology. …”
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The Role of Pharmaceutical Innovation in Clinical Practice Guidelines for Chronic Diseases by Meaghan Roach, Natalie Land, Jennifer Hernandez, Reina Rau, Jacquelyn W. Chou, Stacey S. Hickson, Danielle F. Rollmann, J. Ross Maclean

“…The time from regulatory approval of novel pharmacotherapies to inclusion in guideline recommendations varied considerably by disease area and geography. …”
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The Quality of Veterans Healthcare Administration Cardiovascular Care by D. Elizabeth Le, MD, Bhaskar L. Arora, MBBS, Faith R. Kelly, MD, Stephen W. Waldo, MD, Merritt Raitt, MD, Paul Heidenreich, MD, MS, Samit M. Shah, MD, PhD, Ali E. Denktas, MD, Kreton O. Mavromatis, MD

“…This paper reviews the quality of cardiovascular care delivered by the VHA in comparison to community care, which is care delivered in non-VHA facilities by non-VHA providers and is authorized and paid for by VHA, examining quality metrics and highlighting novel national care programs. The critical examination of this data is valuable for deriving health care policy, sharing novel and effective quality initiatives throughout the healthcare sector, and will help veterans and their providers make important healthcare decisions.…”
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Development of a Deep Learning‐Assisted Mobile Application for the Identification of Nematodes Through Microscopic Images by Naseeb Singh, Ashish Kumar Singh, L. K. Dhruw, Simardeep Kaur, S. Hazarika, K. K. Mishra, V. K. Mishra, Laxmi Kant

“…A novel lightweight convolutional neural network (CNN) was developed to identify the nematodes belonging to different trophic groups (Heterorhabditis indica, Meloidogyne incognita, Helicotylenchus, Anguina tritici, and Xiphinema). …”
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A handheld milk conductivity sensing device (Mylee) for measuring secretory activation progress in lactating women: a device validation study by Sharon Haramati, Anastasia Firsow, Daniela Abigail Navarro, Ravid Shechter

“…Here we evaluate the validity of a novel milk-sensing device (Mylee) for measuring the progress of milk maturation and secretory activation status. …”
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Responses to novelty in wild insular birds: comparing breeding populations in ecologically contrasting habitats by Samara Danel, Nancy Rebout, Léna Bureau, Timothée Zidat, Dora Biro, Francesco Bonadonna

“…In this study, we presented novel objects to two geographically isolated breeding populations of the black-faced sheathbill (Chionis minor), a sedentary land-based bird that frequents remote sub-Antarctic islands. …”
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Circular RNA microarray expression profile and potential function of circDOCK1 in colorectal cancer by Guojing Zhang, Xiaoyan Wu, Hongmin Fu, Daqing Sun

“…Therefore, there exists a critical need to identify novel markers facilitating early CRC detection and prognosis. …”
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A deep learning method for differentiating safflower germplasm using optimal leaf structure features by Hoang Thien Van, Phuong Thuy Khuat, Trang Van, Thai Thanh Tuan, Yong Suk Chung

“…To address this, we introduce a novel comprehensive leaf database of safflower varieties that is meticulously curated by experts. …”
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Metallothionein II treatment mitigates rotenone-induced neurodegeneration in zebrafish models of Parkinson’s disease by Yong Hui Nies, Wei Ling Lim, Norwahidah Abd Karim, Mohamad Fairuz Yahaya, Seong Lin Teoh

“…Current therapies offer symptomatic relief but fail to halt disease progression, highlighting the need for novel therapeutic strategies. This study explores the neuroprotective potential of exogenous human metallothionein 2 (hMT2) peptide in a rotenone-induced PD zebrafish model.MethodsAdult zebrafish were divided into four groups: control, rotenone-treated, hMT2 pre-treatment, and hMT2 co-treatment. …”
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Energy feature extraction and visualization of voltage sags using wavelet packet analysis for enhanced power quality monitoring by M. S. Priyadarshini, Mohit Bajaj, Ievgen Zaitsev

“…This paper introduces a novel approach to voltage sag analysis by employing wavelet packet analysis combined with energy-based feature extraction to enhance PQ monitoring. …”
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