Synthesis, Characterization and Spectroscopic Studies of A Novel 2-[(E)-[(2,4-dichlorophenyl)imino]methyl]phenol Schiff Base and Its Metal Complexes by Eman Turky Shamkhy, Isam Hussain T. Al-Karkhi

“…A novel Schiff base 2-{(E)-[(2,4-dichlorophenyl)imino]methyl}phenol (LB) was synthesized from the condensation reaction of 2,4-dichloroaniline with salicyladehyde in [1:1] ratio in the presence of glacial acetic acid as catalyst. …”
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Economic Evaluation of FebriDx®: A Novel Rapid, Point-of-Care Test for Differentiation of Viral versus Bacterial Acute Respiratory Infection in the United States by Katherine Dick, John Schneider

“…**Objectives:** The primary aim of this study is to conduct a literature-based US economic evaluation of a novel rapid point-of-care test, FebriDx®, that simultaneously measures two key infection biomarkers, C-reactive protein (CRP) and\ Myxovirus resistance protein A (MxA), to accurately differentiate viral from bacterial infection. …”
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Determination of Probiotics Prescription Indications in Patients with Irritable Bowel Syndrome (Materials of the Expert Council and Literature Review) by V. T. Ivashkin, I. V. Maev, O. P. Alekseeva, S. A. Alekseenko, N. V. Korochanskaya, E. A. Poluektova, V. I. Simanenkov, A. S. Trukhmanov, I. B. Khlynov, V. V. Tsukanov, O. S. Shifrin, T. L. Lapina, R. V. Maslennikov, A. I. Ulyanin

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Novel Quantification Method for Lithium Ion Battery Electrolyte Solvents in Aqueous Recycling Samples Using Solid‐Phase Extraction/Gas Chromatography‐Flame Ionization Detection by Julius Buchmann, Yixin Song, Simon Wiemers‐Meyer, Martin Winter, Sascha Nowak

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Process-specific design strategy enables exceptional as-deposited strength-ductility synergy in novel Al–Ce alloys via additive friction stir deposition (AFSD) by Vishal Soni, Roberto Liam Menchaca, Devin Davis, N. Naveen Kumar, Maria Gonzalez, Prithvi Awasthi, Ravi Sankar Haridas, Adam Loukus, David Weiss, Rajiv S. Mishra, Vijay K. Vasudevan

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Intracranial Aneurysms Treated with a Novel Coated Low-Profile Flow Diverter (p48 HPC)—A Single-Center Experience and an Illustrative Case Series by Nadja Krug, Jan S. Kirschke, Christian Maegerlein, Kornelia Kreiser, Maria Wostrack, Bernhard Meyer, Carolin Albrecht, Claus Zimmer, Tobias Boeckh-Behrens, Dominik Sepp

“…<b>Background/Objectives:</b> The p48 MW HPC is a novel low-profile flow diverter covered by a hydrophilic polymer coating with antithrombogenic properties, which may reduce ischemic complications and enable a single antiplatelet therapy after insertion of the stent. …”
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Herb5GluCon: A novel polyherbal formulation with dual-action inhibiting properties against oxidative stress and glycoside hydrolases – an in silico and in vitro approach by Abbirami Balachandran, Patrick N. Okechukwu, Baskaran Gunasekaran, Jeleń Małgorzata, Beata Morak-Młodawska, Gabriele R.A. Froemming, Sameer Sapra, Charlie A. Lavilla, Jr., Merell P. Billacura, Salini D. Rajendran, Anis Najwa Abdul Rani, Anand Gaurav

“…The study aimed to evaluate the antioxidant and anti-glycoside hydrolase potential of a novel polyherbal formulation (Herb5GluCon) and identify its phytoconstituents. …”
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Engineered macrophage nanoparticles enhance microwave ablation efficacy in osteosarcoma via targeting the CD47-SIRPα Axis: A novel Biomimetic immunotherapeutic approach by Xiongfa Ji, Xin Qian, Guowen Luo, Wenjie Yang, Wenhan Huang, Zehua Lei, Jiaqi Zhou, Guoqing Zhong, Jielong Zhou, Nan Liu, Limin Ma, Mei Li, Xiangmei Liu, Shuilin Wu, Yu Zhang

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Global Stability for Novel Complicated SIR Epidemic Models with the Nonlinear Recovery Rate and Transfer from Being Infectious to Being Susceptible to Analyze the Transmission of COVID-19 by Fehaid Salem Alshammari, F. Talay Akyildiz

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A Novel Design, Economic Assessment, and Fuzzy-Based Technical Validation of an Islanded Microgrid: A Case Study on Load Model of Kibber Village in Himachal Pradesh by Sahil Mehta, Prasenjit Basak

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Spontaneously Diabetic Torii (SDT) Fatty Rat, a Novel Animal Model of Type 2 Diabetes Mellitus, Shows Blunted Circadian Rhythms and Melatonin Secretion by Katsuya Sakimura, Tatsuya Maekawa, Shin-ichi Kume, Takeshi Ohta

“…In the present study, we investigated the circadian rhythms of spontaneous locomotor activity, metabolic parameters (plasma glucose, triglyceride, and total cholesterol), and plasma melatonin concentrations in Spontaneously Diabetic Torii (SDT) fatty rats, a novel animal model of type 2 DM. Although SDT fatty rats exhibited low locomotor activity in the dark phase, no phase shifts were observed. …”
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JTT-130, a Novel Intestine-Specific Inhibitor of Microsomal Triglyceride Transfer Protein, Improves Hyperglycemia and Dyslipidemia Independent of Suppression of Food Intake in Diabetic Rats by Shohei Sakata, Makoto Ito, Yasuko Mera, Tomohiko Sasase, Hiromi Yamamoto, Makoto Kakutani, Takeshi Ohta

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Microstructural, mechanical and thermodynamic properties ınvestigation of the novel rare earth-free multicomponent Mg-15Al-8Ca-3Zn-2Ba alloy by Türe Y.

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Quantitative analysis and pharmacokinetic study of a novel diarylurea EGFR inhibitor (ZCJ14) in rat plasma using a validated LC-MS/MS method by Zuo Sai-Jie, Cheng Xiao-Liang, Liu Dong-Zheng, Feng Wei-Yi, Cao Yong-Xiao, Zhang San-Qi

“…1-(4-(Pyrrolidin-1-yl-methyl)phenyl)-3-(4-((3-(trifluoromethyl) phenyl)amino)quinazolin-6-yl)urea (ZCJ14), a novel epidermal growth factor receptor (EGFR) inhibitor, with diarylurea moiety, displays anticancer effect. …”
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Integrating rapamycin with novel PI3K/Akt/mTOR inhibitor microRNAs on NOTCH1-driven T-cell acute lymphoblastic leukemia (T-ALL) by Fateme Arjmand, Samaneh Shojaei, Mitra Khalili, Hossein Dinmohammadi, Behzad Poopak, Samira Mohammadi-Yeganeh, Yousef Mortazavi

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Targeting UGT2B15 and NR1H4 interaction: a novel therapeutic strategy for polycystic ovary syndrome using naftopidil enantiomers by Xiufen Zheng, Zikai Chen, Miao Liang, Liting Zhou, Miaoru Wang, Silin Zhang, Shuyun Zhang, Lei Ma, Wei Yi, Xiawen Liu

“…Conclusions UGT2B15 represents a promising target for novel PCOS therapies by modulating androgen metabolism and protecting ovarian granulosa cells from apoptosis. …”
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A Novel Approach for Treatment of an Unusual Presentation of Radicular Cysts Using Autologous Periosteum and Platelet-Rich Fibrin in Combination with Demineralized Freeze-Dried Bone Allograft by Veena A. Patil, Manthan H. Desai, Veerendra S. Patil, Hanisha Reddy Kaveti, Kiran Kumar Ganji, Prasanna M. Danappanavar

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Development of a Novel, Sensitive, Selective, and Fast Methodology to Determine Malondialdehyde in Leaves of Melon Plants by Ultra-High-Performance Liquid Chromatography-Tandem Mass Spectrometry by Melisa E. Yonny, Ariel Rodríguez Torressi, Mónica A. Nazareno, Soledad Cerutti

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Design, Synthesis, and Performance of Novel Nano‐CoO/NiO‐loaded and Sulfonation‐Modified ZSM‐5 Composite Catalyst for In Situ Conversion of Oil Shale by Aibin Wu, Junwen Wu, Liu Chen, Jianzheng Su, Weichu Yu

“…ABSTRACT A novel composite catalyst with readily preparation and good catalytic performance was designed and synthesized using sulfonation‐modified zeolite socony mobil‐5 (ZSM‐5) as the carrier and nano‐CoO/NiO as the active components. …”
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Spatial and single-cell transcriptomics reveal cellular heterogeneity and a novel cancer-promoting Treg cell subset in human clear-cell renal cell carcinoma by Lijuan Wang, Qian He, Weijun Qin, Xiyu Song, Yumeng Zhu, Wenwen Geng, Jianhua Jiao, Hongjiao Liu, Ruo Chen, Xiuxuan Sun, Jiejie Geng, Zhinan Chen

“…In addition, we traced the origin of IL-1β+ Treg cells and revealed that IL-18 can induce the expression of IL-1β in Treg cells via the ERK/NF-κB pathway.Conclusions We demonstrated a novel cancer-promoting Treg cell subset and its interactions with MRC1+FOLR2+TAMs, which provides new insight into Treg cell heterogeneity and potential therapeutic targets for ccRCC.…”
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