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Auditory Phenotype of a Novel Missense Variant in the CEACAM16 Gene in a Large Russian Family With Autosomal Dominant Nonsyndromic Hearing Loss
Published 2024-03-01“…Hearing loss slowly progresses with age in each person and is similar to age-related hearing loss. We have detected the novel likely pathogenic variant с.419С>T (p.(Thr140Ile)) in exon 3 of the CEACAM16 gene, which segregates with late-onset nonsyndromic hearing loss in this family. …”
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A novel frameshift variant of GATA3 (p.Ala17ProfsTer178) responsible for HDR syndrome in a Japanese family
Published 2024-11-01“…Genetic testing revealed a novel GATA3 gene variant at exon 2 (c.48delC), which induces a frameshift resulting in termination at codon 178, causing HDR syndrome. …”
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Kinetics and mechanisms of 4-chloroguaiacol removal by adsorption onto a novel amorphous carbon thin film synthesized from Hamelia patens leaves
Published 2025-06-01“…This work developed Hamelia patens Jacq leaves (an agricultural waste) as a novel amorphous carbon thin-film (HPL-ACTF) adsorbent, which was successfully employed in removal of 4-chloroguaiacol (4CG) from wastewater. …”
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ZSH‐2208: A novel retinoid with potent anti‐tumour effects on ESCC stem cells via RARγ–TNFAIP3 axis
Published 2025-01-01“…Results This study introduces ZSH‐2208, a novel retinoid specifically targeting ESCC‐TRCs, which holds significant potential for clinical application in ESCC. …”
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Development of a Novel Rapid Immunodiagnostic Kit Based on Flagellar 40 kDa Antigen Epitope for the Detection of Typhoid Fever in Indian Patients
Published 2013-01-01“…To aid the clinical diagnosis of typhoid fever in India, where most hospitals and primary health centres have no facilities for culture, we report on the development of a novel and rapid immunodiagnostic kit for the direct detection of Salmonella Typhi—specific IgG antibodies against S. …”
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A Novel Approach to Faster Convergence and Improved Accuracy in Deep Learning-Based Electrical Energy Consumption Forecast Models for Large Consumer Groups
Published 2025-01-01“…Two important challenges are addressed in this study. Firstly, a novel technique is proposed to accelerate the model training process by selecting optimal mini-batch size. …”
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A novel lectin from mushroom Phellodon melaleucus displays hemagglutination activity, and antitumor activity in a B16 melanoma mouse model
Published 2023-09-01“…A novel lectin (termed PML) was purified from fruiting bodies of the edible mushroom Phellodon melaleucus (division Basidiomycota) by ion exchange, hydrophobic interaction, and gel filtration chromatographies, with overall titer recovery ~60 % and 20-fold purification. …”
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Synthesis, antibacterial evaluation and in silico studies of novel 2-(benzo[d]thiazol-2-yl)-N-arylacetamides and their derivatives as potential DHFR inhibitors
Published 2025-01-01“…Abstract Novel N-arylacetamides 2a–f were synthesized based on benzo[d]thiazole scaffold. …”
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