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SDZ MRL 953, A Novel Synthetic Lipid a Analogue, Induces Tolerance to the Lethal Effects of Endotoxin and Enhances Nonspecific Immunity
Published 1992-01-01“…An attractive alternative appears to be the induction of hyporesponsiveness to LPS by synthetic lipid A analogues. SDZ MRL 953, a novel prototype of lipid A analogues. was examined for its ability to induce early-phase tolerance against experimental endotoxemia in mice following single or multiple administrations 2, 24, or 72 h before challenge. …”
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2742
Effectiveness of a novel amine + zinc + fluoride toothpaste in reducing plaque and gingivitis: results of a six-month randomized controlled trial
Published 2025-02-01“…Conclusions The amine + zinc + fluoride toothpaste significantly improved measures of plaque (12× more effective) and gingivitis (5× more effective) in comparison to a standard fluoride toothpaste, suggesting that the novel formulation with antibacterial active ingredients amine and zinc facilitates more effective plaque removal, and promotes gingival health. …”
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A Novel Hybrid Model for Credit Risk Assessment of Supply Chain Finance Based on Topological Data Analysis and Graph Neural Network
Published 2025-01-01“…This study proposes a novel hybrid Topological Data Analysis (TDA) and Graph Neural Network (GNN) to optimize credit risk assessment in SCF. …”
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2747
Characterization and Machine Learning-Driven Property Prediction of a Novel Hybrid Hydrogel Bioink Considering Extrusion-Based 3D Bioprinting
Published 2025-01-01“…To address this gap, our research presents predictive models using machine learning (ML) algorithms, including polynomial fit (PF), decision tree (DT), and random forest (RF), to estimate bioink viscosity based on component weights and shear rate. We utilized novel bioinks composed of varying percentages of alginate (2–5.25%), gelatin (2–5.25%), and TEMPO-Nano fibrillated cellulose (0.5–1%) at shear rates from 0.1 to 100 s<sup>−1</sup>. …”
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Implementation of prehospital point-of-care ultrasound using a novel continuous feedback approach in a UK helicopter emergency medical service
Published 2025-02-01“…This paper describes a novel approach to implementation of prehospital PoCUS and clinical governance framework in a UK HEMS. …”
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“If Jesus lived today, he would smell like smoke”: Contemporary Visions of Jesus Christ in Philip Pullman’s Novel and Tumblr Blogs
Published 2024-10-01“…The interpretation of Pullman’s novel and the selected poems is placed within the context of past and current struggles over the historicity, human/divine status, and politics of Jesus Christ. …”
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DeepGenMon: A Novel Framework for Monkeypox Classification Integrating Lightweight Attention-Based Deep Learning and a Genetic Algorithm
Published 2025-01-01“…<b>Methods</b>: This paper proposes a novel lightweight framework called DeepGenMonto accurately classify various types of skin diseases, such as chickenpox, melasma, monkeypox, and others. …”
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Short-Term Effects of a Novel Eye Mask Producing Heat and Vibration for the Treatment of Meibomian Gland Dysfunction: A Pilot Study
Published 2021-01-01“…To investigate the short-term effects on tear film parameters and ocular symptoms of a novel eye mask producing heat and vibration developed for the treatment of dry eye disease owing to meibomian gland dysfunction (MGD). …”
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Synthesis, Characterization and Antifungal Activity of Novel Quinazolin-4-one Derivatives Containing 8-Hydroxyquinazoline Ligand and its Various Metal Complexes
Published 2009-01-01“…Novel ligands containing quinazoline-4-one-8-hydroxyquinoline (QQ) merged moieties were prepared and characterized. …”
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