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2141
Novel anthropometric indices are superior adiposity indexes to portend visual impairment in middle-aged and older Chinese population
Published 2024-05-01“…Objective To investigate differential associations of traditional and novel adiposity indices with visual impairment (VI) in the middle-aged and older Chinese population.Methods and analysis Based on the China Health and Retirement Longitudinal Study, 7750 Chinese older adults aged over 45 were included at baseline 2011, and 4133 participants who accomplished all three interviews from 2011 to 2015 were adapted for longitudinal analyses. …”
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2142
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2143
A Novel Mechanism-Equivalence-Based Tweedie Exponential Dispersion Process for Adaptive Degradation Modeling and Life Prediction
Published 2025-01-01“…To address these issues, we propose a novel mechanism-equivalence-based Tweedie exponential dispersion process (ME-based TEDP) for adaptive degradation modeling and RUL prediction of mechanical components. …”
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2145
Hypericum Perforatum-Derived Exosomes-Like Nanovesicles: A Novel Natural Photosensitizer for Effective Tumor Photodynamic Therapy
Published 2025-02-01“…In vivo, HPDEN-mediated PDT significantly suppressed tumor growth and induced extensive tumor necrosis, with no observable toxicity to major organs.Conclusion: HPDENs represent a novel plant-derived photosensitizer with dual ROS generation pathways and significant therapeutic efficacy, providing a promising platform for enhancing photodynamic therapy.Keywords: Hypericum perforatum-derived exosomes-like nanovesicles, photosensitizer, photodynamic therapy, reactive oxygen species, apoptosis…”
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2146
CADD-based discovery of novel oligomeric modulators of PKM2 with antitumor activity in aggressive human glioblastoma models
Published 2025-02-01“…The unique exon ten at the dimer-dimer interface represents an attractive target for isoform-specific modulation, offering opportunities for disrupting this equilibrium and altering tumour cell dynamics.This study identifies a novel druggable pocket at the PKM2 dimer interface through conformational analysis. …”
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2147
A Novel High-Power Dual-Band Coupled-Line Gysel Power Divider with Impedance-Transforming Functions
Published 2014-01-01“…A novel coupled-line structure is proposed to design dual-band and high-power Gysel power dividers with inherent impedance-transforming functions. …”
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2149
The Structural Design, Kinematics, and Workspace Analysis of a Novel Rod–Cable Hybrid Cable-Driven Parallel Robot
Published 2024-12-01“…This study presents a novel rod–cable hybrid planar cable-driven parallel robot inspired by the biological synergy of bones and muscles. …”
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2152
A novel configuration for single-crystal superalloy hollow blade manufacturing based on shell/core integral mold
Published 2025-03-01“…Shell/core integral mold fabricated by additive manufacturing possess high shell/core bonding strength, which is promising to improve the dimensional accuracy and integrity of single-crystal (SX) hollow blade while improving the manufacturing efficiency. In this study, a novel inverted configuration of SX hollow blade was proposed based on shell/core integral mold, resulting in a 55 mm reduction of platform height compared to the upright configuration. …”
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2153
Denoising deep brain stimulation pacemaker signals with novel polymer-based nanocomposites: Porous biomaterials for sound absorption
Published 2024-07-01“…To mitigate this issue, we propose a novel polymer-based nanocomposite for pacemakers for signal denoising. …”
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2154
DNAH11 and a Novel Genetic Variant Associated with Situs Inversus: A Case Report and Review of the Literature
Published 2023-01-01“…Conclusion. We reported a novel homozygous nonsense variant in DNAH11 in a 3-year-old boy with primary ciliary dyskinesia. …”
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2155
A Novel Method for Constructing Grid Multi-Wing Butterfly Chaotic Attractors via Nonlinear Coupling Control
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Novel Pathogenic Variant in TGFBR2 Confirmed by Molecular Modeling Is a Rare Cause of Loeys-Dietz Syndrome
Published 2017-01-01“…We report a case of a novel pathogenic variant in TGFBR2 and phenotype consistent with classic LDS. …”
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2158
Identification of novel anti-CD16a antibody clones for the development of effective natural killer cell engagers
Published 2024-12-01“…These anti-CD16a antibody clones are promising candidates for combination with any TAA of interest, offering the potential for novel NK cell engager-based cancer therapeutics that are minimally affected by the high concentrations of human IgG in the circulation.…”
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2159
A novel dual fixation method for improving the reliable assessment of pulmonary vascular morphology in pulmonary hypertension rats
Published 2025-01-01“…Abstract This study introduced a novel dual fixation method for the pulmonary vasculature and lung tissue in pulmonary hypertension (PH) rats, addressing the limitations of traditional fixation methods that failed to accurately preserve the in vivo status of pulmonary vascular morphology. …”
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2160
Design, Fabrication, and Efficiency Study of a Novel Solar Thermal Water Heating System: Towards Sustainable Development
Published 2016-01-01“…This paper investigated a novel loop-heat-pipe based solar thermal heat-pump system for small scale hot water production for household purposes. …”
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