Dealing With the Complexity of Effective Population Size in Conservation Practice by Ancuta Fedorca, Joachim Mergeay, Adejoke O. Akinyele, Tamer Albayrak, Iris Biebach, Alice Brambilla, Pamela A. Burger, Elena Buzan, Ino Curik, Roberta Gargiulo, José A. Godoy, Santiago C. González‐Martínez, Christine Grossen, Myriam Heuertz, Sean Hoban, Jo Howard‐McCombe, Maria Kachamakova, Peter Klinga, Viktoria Köppä, Elenora Neugebauer, Ivan Paz‐Vinas, Peter B. Pearman, Laia Pérez‐Sorribes, Baruch Rinkevich, Isa‐Rita M. Russo, Adélaïde Theraroz, Nia E. Thomas, Marjana Westergren, Sven Winter, Linda Laikre, Alexander Kopatz

“…The overarching goal was to operationalize the current knowledge of Ne estimation methods for conservation practitioners and decision‐makers. We set out to identify datasets to evaluate the sensitivity of Ne estimation methods to violations of underlying assumptions and to develop data analysis strategies that addressed pressing issues in biodiversity monitoring and conservation. …”
Get full text

Identification of Southeast Asian Anopheles mosquito species with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry using a cross-correlation approach by Victor Chaumeau, Sunisa Sawasdichai, Thu Zar Ma Ma Moe Min, Thithiwarada Kularbkeeree, Naw Jaruwan, Naw Gloria, Naw Yu Lee, Muesuwa Trackoolchengkaew, Monticha Phanaphadungtham, Patcharamai Rongthong, Aritsara Inta, Wanitda Watthanaworawit, François Nosten

“…A simulation experiment was carried out by querying the reference database with the spectra of the test panel to evaluate the performance of species identification with MALDI–TOF MS at varying thresholds of the cross-correlation index for the algorithm to output an identification result and with varying numbers of technical replicates for the tested specimens, considering PCR identification results as the reference. …”
Get full text

Fractionated robotic radiosurgery for unfavorable nonfunctioning pituitary macroadenoma: 5-year outcomes from a single institution protocol by Akrita Bhatnagar, Monica Pernia Marin, Jonathan W. Lischalk, Min Ji Koh, Siviero Agazzi, Simeng Suy, Brent T. Harris, Susmeeta T. Sharma, Edward Aulisi, Amjad Anaizi, Mohamed H. Khattab, Walter C. Jean, Walter C. Jean, Sean P. Collins, Brian T. Collins

“…There was one in-field failure pathologically confirmed following surgery for pituitary hemorrhage and two radiographically confirmed out-of-field failures in patients with larger tumors (>20 cc).ConclusionsThe treatment of unfavorable nonfunctioning pituitary macroadenoma with 5-fraction robotic radiosurgery provides excellent local control to date, with acceptable toxicity. …”
Get full text

AI-Driven Innovations for Early Sepsis Detection by Combining Predictive Accuracy With Blood Count Analysis in an Emergency Setting: Retrospective Study by Tai-Han Lin, Hsing-Yi Chung, Ming-Jr Jian, Chih-Kai Chang, Hung-Hsin Lin, Chiung-Tzu Yen, Sheng-Hui Tang, Pin-Ching Pan, Cherng-Lih Perng, Feng-Yee Chang, Chien-Wen Chen, Hung-Sheng Shang

“…ResultsPathogen identification in ICU patients found 243 FilmArray-positive, 411 culture-positive, and 92 undetected cases, yielding a final dataset of 654 (43.8%) sepsis cases out of 1492 total cases. The machine learning models demonstrated high predictive accuracy, with LGBM achieving the highest area under the curve (0.90), followed by the random forest classifier (0.89) and gradient boosting classifier (0.88). …”
Get full text

Fifteen-second bouts of hyperoxia improve 5-minute time-trial performance in acute hypoxic conditions by Martin Faulhaber, Sina Schneider, Linda K. Rausch, Tobias Dünnwald, Verena Menz, Hannes Gatterer, Michael D. Kennedy, Wolfgang Schobersberger

“…The positive effects of continuous hyperoxia during aerobic high-intensity exercise has been shown repeatedly, however, the potential effects of intermittent doses are unclear. Out study aimed to test the effects of repeated bouts of hyperoxia, each lasting fifteen seconds, on maximal 5-minute cycling performance under acute hypoxic conditions. …”
Get full text

Bees on the run: Nosema spp. (Microsporidia) in Apis mellifera and related products, Italy by Giovanni Sgroi, Luigi Jacopo D’Auria, Luigi Jacopo D’Auria, Maria Gabriella Lucibelli, Andrea Mancusi, Yolande Thérèsa Rose Proroga, Mauro Esposito, Mauro Esposito, Simona Rea, Daniel Signorelli, Federica Gargano, Nicola D’Alessio, Ranju Ravindran Santhakumari Manoj, Peyman Khademi, Giuseppe Rofrano, Giuseppe Rofrano

“…Signs/symptoms of nosemosis were monitored and collected by the cooperation of beekeepers.ResultsOut of 10 apiaries, 6 (i.e., 60%, 95% CI: 31.3–83.2) tested positive for at least one sample to Nosema spp. …”
Get full text

Process evaluation of Project Daire: a food environment intervention that impacted food knowledge, wellbeing and dietary habits of primary school children by Naomi Anderson, Sarah F. Brennan, Fiona Lavelle, Sarah E. Moore, Dilara Olgacher, Amy Junkin, Moira Dean, Michelle C. McKinley, Patrick McCole, Ruth F. Hunter, Laura Dunne, Niamh E. O’Connell, Chris T. Elliott, Danielle McCarthy, Jayne V. Woodside

“…A sustainable funding and resourcing mechanism is required for successful future roll-out across the UK and beyond. Trial registrations The original trial referenced in this process evaluation is registered as follows: National Institute of Health (NIH) U.S. …”
Get full text

Protective Effects of Phycobiliproteins from <i>Arthrospira maxima</i> (Spirulina) Against Cyclophosphamide-Induced Embryotoxicity and Genotoxicity in Pregnant CD1 Mice by Yuliana García-Martínez, Amparo Celene Razo-Estrada, Ricardo Pérez-Pastén-Borja, Candelaria Galván-Colorado, Germán Chamorro-Cevallos, José Jorge Chanona-Pérez, Oscar Alberto López-Canales, Hariz Islas-Flores, Salud Pérez-Gutiérrez, Joaquín Cordero-Martínez, José Melesio Cristóbal-Luna

“…<b>Background/Objectives</b>: In recent years the global incidence of cancer during pregnancy is rising, occurring in 1 out of every 1000 pregnancies. In this regard, the most used chemotherapy drugs to treat cancer are alkylating agents such as cyclophosphamide (Cp). …”
Get full text

In Situ Growth of (−201) Fiber‐Textured β‐Ga2O3 Semiconductor Tape for Flexible Thin‐Film Transistor by Xiao Tang, Yue Zhao, Kuang‐Hui Li, Chen Liu, Hendrik Faber, Wedyan Babatain, Che‐Hao Liao, Saravanan Yuvaraja, Vishal Khandelwal, Dhanu Chettri, Haicheng Cao, Yi Lu, Chuanju Wang, Thomas D. Anthopoulos, Xixiang Zhang, Xiaohang Li

“…With pulsed laser deposition under high temperature, as‐grown Ga2O3 thin films have a fabric texture with a preferred out‐of‐plane orientation along (−201) and a good field‐effect mobility of 18.07 cm2 V−1 s−1. …”
Get full text

COSMIC’s Large-scale Search for Technosignatures during the VLA Sky Survey: Survey Description and First Results by C. D. Tremblay, J. Sofair, L. Steffes, T. Myburgh, D. Czech, P. B. Demorest, R. A. Donnachie, A. W. Pollak, M. Ruzindana, Siemion A. P. V., S. S. Varghese, S. Z. Sheikh

“…In this paper, we describe a postprocessing pipeline to identify persistent sources of interference, filter out false positives, and search for signals not immediately identifiable as anthropogenic radio frequency interference during the VLA Sky Survey. …”
Get full text

Removal and adsorption kinetics of copper(II) ions from aqueous media on activated carbon in dynamic adsorption on a fixed-bed column by Mve Mfoumou, Charly, Tonda-Mikiéla, Pradel, Ngoye, Francis, Bouassa Mougnala, Spenseur, Mbouiti, Berthy Lionel, Feuya Tchouya, Guy Raymond

“…Dynamic adsorption experiments on fixed-bed columns and adsorption kinetics studies of Cu2+ in aqueous media, under various experimental conditions, were carried out on activated carbon (AC) prepared using coconut shells from Franceville (Gabon). …”
Get full text

Causal role of plasma liposome in diabetic retinopathy: mendelian randomization (MR) study by Kai Yin, Lu Ding, Xueyan Li, Yuqi Zhang, Siyu Song, Liyuan Cao, Ruixue Deng, Min Li, Zirui Li, Qinjing Xia, Daqing Zhao, Xiangyan Li, Zeyu Wang

“…The robustness of our findings was assessed using leave-one-out and funnel plots. To further assess the reliability of the results, linkage disequilibrium score regressions, colocalization analysis and reverse MR analysis were also performed. …”
Get full text

The efficacy of sinustrabeculectomy in the modern clinical practice by A.V. Antonova, V.P. Nikolaenko, V.V. Brzheskiy, A.Ya. Vuks

“…Petersburg, Russian Federation </p> <p> <br> </p> <p> <b>Aim</b>: to assess the hypotensive effect of sinustrabeculectomy (STE) carried out within the "cascade" treatment algorithm for glaucoma. …”
Get full text

Disparities in dolutegravir utilisation in children, adolescents and young adults (0–24 years) living with HIV. An analysis of the IeDEA Pediatric West African cohort by Valériane Leroy, Anandi Sheth, Julie Jesson, Jean Jacques Koffi, Antoine Jaquet, François Dabis, Didier Koumavi Ekouevi, Karen Malateste, Olivia Keiser, Lehila Bagnan, Simon Boni, Madeleine Amorissani Folquet, Mariam Sylla, Olivier Marcy, Raoul Moh, Gildas Boris Hedible, Sophie Desmonde, Joycelyn Dame, Agatha David, Madeleine Amorissani-Folquet, Sylvie N'Gbeche, Elom Takassi, François Tanoh Eboua, Kouadio Kouakou, Lehila Bagnan Tossa, Caroline Yonaba, Jocelyn Dame, Sylvie Marie N’Gbeche, Fatoumata Dicko Traore, Oliver Ezchechi, Rosemary Audu, Charlotte Bernard, Caroline Couturier, Marie Kerbie Plaisy, Elodie Rabourdin, Thierry Tiendrebeogo, Désiré Dahourou, Emile Sodinyessi, Jean-Claude Azani, Kadidja Diarra, Maika Bengali, Abdoulaye Cissé, Guy Gnepa, Eric Komena, Séverin Lenaud, Eulalie Kangah, Igho Ofotokun, Cecile Delille Lahiri, Noëlle Benzekri, Geoffrey Gottlieb

“…Adjusted on ART line and available viral load (VL) at baseline, females aged &gt;10 years were less likely to initiate DTG compared with males of the same age (adjusted HR among 10–14 years: 0.62, 95% CI 0.54 to 0.72; among ≥15 years: 0.43, 95% CI 0.36 to 0.50), as were those with detectable VL (&gt;50 copies/mL) compared with those in viral suppression (aHR 0.86, 95% CI 0.77 to 0.97) and those on PIs compared with those on non-nucleoside reverse-transcriptase inhibitors (aHR after 12 months of roll-out: 0.75, 95% CI 0.65 to 0.86).Conclusion Paediatric DTG uptake was incomplete and unequitable in west African settings: DTG use was least likely in children &lt;5 years, females ≥10 years and those with detectable VL. …”
Get full text

Theoretical and applied research on hydraulic slit-fracture joint roof control and pressure relief of hard roof in goaf roadway by Yongjiang ZHANG, Fei JI, Tongbin ZHAO, Ke YANG, Wenbin WU, Wangang JIANG

“…Based on the above research, an industrial test was carried out at the 81403 working face of the Huayang mine. …”
Get full text

Integrated bioinformatics analysis to explore potential therapeutic targets and drugs for small cell carcinoma of the esophagus by Maofei Zhu, Maofei Zhu, Yueming Chu, Yueming Chu, Qiang Yuan, Qiang Yuan, Junfeng Li, Silin Chen, Lin Li, Lin Li, Lin Li

“…GO and KEGG analysis of DEGs were carried out by using the Bioinformatics and OmicStudio tools. …”
Get full text

Pilot study of a ketogenic diet in bipolar disorder: a process evaluation by Benjamin P. Rigby, Nicole Needham, Helen Grossi, Ivana Kamenska, Iain H. Campbell, Ben Meadowcroft, Frances Creasy, Cheryl Fisher, Pankaj Bahuguna, John Norrie, Gerard Thompson, Melissa C. Gibbs, Maja Mitchell-Grigorjeva, Ailsa McLellan, Tessa Moses, Karl Burgess, Rachel Brown, Michael J. Thrippleton, Harry Campbell, Daniel J. Smith, Sharon A. Simpson

“…Semi-structured telephone interviews were carried out with 15 participants 1–2 months after completing a 6–8 week modified ketogenic diet intervention, and 4 research clinicians from the study team following the completion of data collection. …”
Get full text

Machine learning for predicting neoadjuvant chemotherapy effectiveness using ultrasound radiomics features and routine clinical data of patients with breast cancer by Pu Zhou, Pu Zhou, Hongyan Qian, Pengfei Zhu, Jiangyuan Ben, Jiangyuan Ben, Guifang Chen, Qiuyi Chen, Lingli Chen, Jia Chen, Ying He, Ying He

“…The diagnostic process of the ML model was visualized and analyzed using SHapley Additive exPlanation (SHAP).ResultsOut of 231 participants with BC, 98 (42.42%) achieved pCR, and 133 (57.58%) did not. …”
Get full text

Optimasi Algoritma Naive Bayes dengan Diskritisasi K-Means pada Diagnosis Penyakit Jantung by Nafa Fajriati, Budi Prasetiyo

“…Diagnosis of the disease is an important process that must be carried out accurately to avoid misdiagnosis. Data mining can be applied to improve accuracy and reduce the number of misdiagnoses. …”
Get full text

Donor-Specific Anti-Human Leukocyte Antigen Antibodies Predict Prolonged Isolated Thrombocytopenia and Inferior Outcomes of Haploidentical Hematopoietic Stem Cell Transplantation by Xiaosu Zhao, Xiangyu Zhao, Mingrui Huo, Qiaozhen Fan, Xuying Pei, Yu Wang, Xiaohui Zhang, Lanping Xu, Xiaojun Huang, Kaiyan Liu, Yingjun Chang

“…Our results, for the first time, suggest an association of DSAs with PT after unmanipulated HBMT. It would help screen out the suitable donor and guide intervention. This indicated that DSAs should be incorporated in the algorithm for unmanipulated HBMT.…”
Get full text