EIF4A3-induced circ_0022382 promotes breast cancer cell progression through the let-7a-5p/PI3K/AKT/mTOR signaling pathway and SLC7A11 axis by Wei Liu, Wei Liu, Jun Zhang, Jiawen Zhang, Yu Ye, Jianqin Zhu, Qiwen Yu, Tao Li, Tao Li, Xiaochun Sun, Huabiao Chen, Huabiao Chen

“…In this study, we explored the impacts of circRNAs on the progression of breast cancer cells.MethodsUsing bioinformatics analysis, we screened out one up-regulated circRNA in breast cancer, and its function and regulatory mechanisms were confirmed by quantitative real-time PCR, cell counting kit-8 experiment, migration assay, dual luciferase reporter assay, Kyoto Encyclopedia of Genes and Genomes enrichment analysis, cell immunofluorescence, clone formation assay, scratch wound healing experiment, RNA immunoprecipitation and subcutaneous tumor-bearing experiments.ResultsCirc_0022382 was highly expressed in breast cancer cell lines MDA-MB-231, MCF-7 as well as breast cancer tissues, and promoted the proliferative and migratory capacity of breast cancer cells. …”
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Odpowiedź na pracę dr. Pawła E. Tomaszewskiego pt. „Komentarz do artykułu Mariusza W. Majewskiego opublikowanego w Studia Historiae Scientiarum 17 (2018), ss. 89–117” by Mariusz W. Majewski

“…The author proposes that a systematic team inquiry into both press and archival resources regarding Jan Czochralski should be carried out, and researchers should be allowed access to respective private archives. …”
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Exploring the mechanism of rosmarinic acid in the treatment of lung adenocarcinoma based on bioinformatics methods and experimental validation by Chaowang Zhou, Ruqian Zhong, Lei Zhang, Renyi Yang, Yuxin Luo, Huijun Lei, Liang Li, Jianzhong Cao, Zhiying Yuan, Xiaoning Tan, Mengzhou Xie, Haoyu Qu, Zuomei He

“…Then, molecular docking between hub RDEGs and RosA was performed, and further evaluation was carried out by using bioinformatics for the predictive value of the hub RDEGs. …”
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A workplace-based HIV self-testing intervention as a determinant for self-testing knowledge, beliefs, and use among unskilled workers in Wakiso Uganda by Gerald Mukisa Nsereko, Khamisi Musanje, Eron Robinah Ayesiga, Loyce Kiiza Kobusingye, Rhoda Namubiru, Moses Sempala, Christine Kiwala, Martin Mabunda Baluku

“…Therefore, this study set out to examine the effect of a workplace-based HIV self-testing intervention on the use of HIV self-testing among unskilled workers in Wakiso Uganda. …”
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Emergence of Pituitary Adenoma in a Child during Surveillance: Clinical Challenges and the Family Members’ View in an AIP Mutation-Positive Family by Pedro Marques, Sayka Barry, Amy Ronaldson, Arla Ogilvie, Helen L. Storr, Peter J. Goadsby, Michael Powell, Mary N. Dang, Harvinder S. Chahal, Jane Evanson, Ajith V. Kumar, Joan Grieve, Márta Korbonits

“…A 12-year-old niece developed headache and her MRI showed a microadenoma, not seen on a pituitary MRI scan 3 years earlier. Discussion. Out of the 14 members harbouring germline AIP mutations in this kindred, 5 have pituitary adenoma. …”
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Nature and Origin of Mineralizing Fluids in Hyperextensional Systems: The Case of Cretaceous Mg Metasomatism in the Pyrenees by Benoît Quesnel, Marie-Christine Boiron, Michel Cathelineau, Laurent Truche, Thomas Rigaudier, Gérard Bardoux, Pierre Agrinier, Michel de Saint Blanquat, Emmanuel Masini, Eric C. Gaucher

“…Stable isotope analyses (δ13C, δ18O, δD, and δ37Cl) and Cl/Br ratio measurements in fluid inclusions and their host minerals were carried out in order to determine the origin of the fluid(s) involved in the formation of the ore deposit. …”
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Multilocus Family-Based Association Analysis of Seven Candidate Polymorphisms with Essential Hypertension in an African-Derived Semi-Isolated Brazilian Population by L. Kimura, C. B. Angeli, M. T. B. M. Auricchio, G. R. Fernandes, A. C. Pereira, J. P. Vicente, T. V. Pereira, R. C. Mingroni-Netto

“…Methods. Analyses were carried out using a family-based design in a sample of 652 participants (97 families). …”
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The Role of School Management Committee and Pupils' Performance in Government Primary Schools in RuhiJa Town Council Rubanda District. by Niwagaba, Alex

“…The recommendations included; the school management committee through meetings with members of teaching staff and their head teachers should advise them properly and allow them to execute their duties as expected in order to alleviate levels of understanding to children that lead to excellent academic performance; more research should be carried out to allow the school management committees not to dwell on advising head teachers only on matters of children's performance by suggesting strategies but also the entire stakeholders whose effort can promote academic performance of children in primary schools; need to formulate academic committees advised by the members of school management committee on how to perform through motivational element aiming at doing well academically to promote the names of the school; it is imperative that the schools get in touch with the members of the school management committees who have some formal education to quickly understand the value of education and how plans for developments of certain sectors in school especially academic performance could be made; need to foster supervision that involves cooperation towards pupils 'performance by all stakeholders; appointing an active team that can do supervision to let children advance academically is healthy.…”
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Assessing the Factors Influencing Attrition of Health Workers in Government Health Units in Lyantonde District, Uganda. by Kansiime, Benon

“…This was guided by three specific objectives of the study which were to: find out the drivers of attrition of health workers in Lyantonde district; determine the effects of attrition of health workers in Lyantonde district; and establish retention measures of health workers in Lyantonde district. …”
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Production of Biogas from Bio-Degradable Municipal Solid Waste – A Way of Resource Recovery. by Atatiru, Faiza

“…Considering the percentages obtained above, the three most dominant are food wastes, garden trimmings and paper wastes and these were used for carrying out the exercise. 5kg these three were taken to the laboratory for proximate and ultimate analyses. …”
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Management Control System and Financial Performance of Micro Finance Institutions in Central Region Uganda by Arthur, Sunday, Caleb, Tamwesigire, Caroline Masiko, Murezi, George Stanley, Kinyata, Godfrey, Barigye, Keneth, Nuwagira, Moses, Agaba

“…Therefore, this study is important not only because it fills the gap, but also it is set out to address this evident knowledge gap. The study adopted positive-phenomenological, epistemology and quantitative-qualitative methodology dimension with cross sectional and correlation designs, the unit of analysis was Microfinance Institutions registered with Association of Microfinance Institutions, and employees were the units of inquiry. …”
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Human Resource Practices and Employee Retention in Local Governments in Uganda: A Case of Kabale District Local Government. by Baingana, Alex

“…The study targeted 134 participants, but 119 managed to respond, including 117 who filled out the questionnaire and 02 who were interviewed. …”
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Human Resource Practices and Employee Retention in Local Governments in Uganda: A Case of Kabale District Local Government. by Baingana, Alex

“…The study targeted 134 participants, but 119 managed to respond, including 117 who filled out the questionnaire and 02 who were interviewed. …”
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Adverse Maternal Outcomes and Associated Factors Among Mothers of Advanced Age delivering at a Tertiary Hospital, Southwestern Uganda: A Cross-Sectional Study. by Masembe, Sezalio, Migisha, Richard, Turyasingura, Godwin, Aheisibwe, Hillary, Nzabandora, Emmanuel, Lule, John C.

“…We identified factors associated with adverse outcomes using modified Poisson regression. Results Out of 417 participants, most were aged 35–37 years (n=206; 49.4%), and had parity≥5 (65.5%). …”
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Application Of ArtifiCial Intelligence in E-Governance: A Comparative Study of Supervised Machine Learning and Ensemble Learning Algorithms on Crime Prediction. by Niyonzima, Ivan, Muhaise, Hussein, Akankwasa, Aureri

“…Advancement in information and communications technology enables law enforcement agencies to collect a huge amount of crime data, and the data collected by these organizaions have been doubling every two years. It has been found out that only 17% of the collected crime data is used in their operations today and several studies have noted that Law Enforcement Agencies are data rich but information poor. …”
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Information Communication Technology and Service Delivery in Nyagatare District Local Goverment, Rwanda. by Wellars, Kanamugire

“…The study further recommends that special emphasis is needed in working out revenue models, ensuring the full implementations of ICT through appropriate tenure appointment of project champions, ensuring effective monitoring and maintenance of ICT systems, among others.…”
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Community Work Participation and Outcomes in Nyagatare District, Rwanda. by Jean Marie Vianney, Ruzindana

“…Among the challenges included limited equipment and materials to use while carrying out community work activities in the study area and the culture of the people especially those from the traditional loyal wealth families posed a challenge to community work in the study area. …”
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Modelling and Analysis of Bioretention Systems for Removal of Stormwater Pollutants by Nuwagaba, Emmanuel, Abdulkadir, Taofeeq Sholagberu, Agwe, Michael Tobby, Philip, Tibenderana, Ako, Terseer, Moses N., Twesigye-omwe

“…The plants were introduced into columns C leaving out B as control experiment. Materials used in the media structure were analyzed to meet the standards according to the design manual. …”
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Misconceptions on COVID-19 Risk Among Ugandan Men: Results From a Rapid Exploratory Survey, April 2020 by Keneth Iceland, Kasozi, MacLeod, Ewan, Ssempijja, Fred, Mahero, Michael W., Matama, Kevin, Musoke, Grace Henry, Bardosh, Kevin, Ssebuufu, Robinson, Wakoko-Studstil, Florence, Echoru, Isaac, Tiyo Ayikobua, Emmanuel, Mujinya, Regan, Nambuya, Grace, Onohuean, Hope, Zirintunda, Gerald, Ekou, Justine, Welburn, Susan Christina

“…Methods: A cross-sectional survey carried out in early April 2020 was conducted with 161 Ugandans, who purposively participated in the online questionnaire that assessed understandings of COVID-19 risk and infection. …”
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Investigating The Performance Of Local And Indigenous Businesses In Times Of Economic Recession With Emphasis On Developing The Capabilities Of Cooperatives In Sistan And Baluchest... by Ali Asghar Tabavar, Abdoulnaser Derakhshan, Sahar Arefi

“…The first step in carrying out the estimation approach of vector error correction models is to check the meanness of the data. …”
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