Mechanisms of oral ciprofloxacin-induced depressive-like behavior and the potential benefit of lactulose: A correlation analysis by Havizur Rahman, Kusnandar Anggadiredja, Lucy Sasongko

“…This study indicate that ciprofloxacin induce depression-like behavior via modulation of several neurotransmitter system as well as proinflammatory cytokines in the hippocampus and prefrontal cortex. …”
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Comparing the Efficacy of Probiotic Nutraceuticals and Probiotic Food (Curd) in Combination with Antidepressants for Depression by T. D. Sanmith, Jitendra Chourasiya, Nishant Patel

“…Recent research has explored the gut–brain axis, emphasizing the role of microbiota in neurotransmitter production. This study aims to explore the effectiveness of two complementary probiotic interventions: probiotic-rich curd and probiotic capsules, used in combination with the antidepressant escitalopram over 4 weeks. …”
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Movement in the Shadow of Sadness: How Physical Activity Supports the Fight Against Depression by Agata Ossolińska, Patrycja Marta, Filip Huzarski, Gabriela Ferfecka, Klaudia Pawełek, Lucyna Stolarska, Magdalena Rosa-Bończak, Natalia Morawiecka, Olivier Carlton, Weronika Kłosowicz

“…Exercise also affects the balance of neurotransmitters, such as serotonin, dopamine, and GABA, contributing to improved mood, cognitive abilities, and quality of life. …”
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A Review on The Impact of Thermal Stress on Fish Biochemistry by Manoj Kumar Pati, Mohammad Aftabuddin, Prasun Roychowdhury

“…Stress responses occur at neurotransmitter and hormonal levels, progressing to peripheral and organism-wide effects. …”
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Nutritional and Functional Composition of Barley Varieties From Legambo District, Ethiopia by Yalew Yiblet, Worku Misganaw, Endale Adamu

“…Barley amino acids are essential nutrients for various biological processes, muscle repair, immunological system function, neurotransmitter generation, and detoxification.…”
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Neurotoxicological Effects of Some Mycotoxins on Humans Health and Methods of Neuroprotection by Aleksandra Kuć-Szymanek, Daria Kubik-Machura, Klaudia Kościelecka, Tomasz Męcik-Kronenberg, Lidia Radko

“…They are mainly related to the increase in oxidative stress in neuronal cells, which leads to higher levels of pro-inflammatory cytokines as IL-1β, IL-6 and TNF-α, enzymatic activity as GST, GPx, CAT and SOD and neurotransmitter dysfunction (5-HT, serotonin, dopamine and GABA). …”
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Inside the impulsive brain: a narrative review on the role of neurobiological, hormonal and genetic factors influencing impulsivity in psychiatric disorders by Hannah Raji, Susha Dinesh, Sameer Sharma

“…The nexus between impulsivity and substance use disorders emphasizes the intricate involvement of neurobiological, neurotransmitter, and genetic components, guiding targeted interventions. …”
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Therapeutic Implications of a Polymethoxylated Flavone, Tangeretin, in the Management of Cancer via Modulation of Different Molecular Pathways by El-Shaimaa A. Arafa, Noura T. Shurrab, Manal A. Buabeid

“…Chemotherapeutics can induce oxidative stress, inflammation, apoptosis, mitochondrial dysfunction, and abnormalities in neurotransmitter metabolism leading to toxicity. Because there have been no therapeutic strategies developed to target inflammation and oxidative stress, there is a continuing need for new and improved therapy. …”
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Mechanism of Transcranial Magnetic Stimulation in the Treatment of Neuropathic Pain by SUN Yu-jia, ZHANG Jun-feng, YAN Long, FAN Shi-yu, QIAN Yu-lin, CONG Shan, YU Tao

“…The mechanisms discussed include modulation of synaptic plasticity，functional reorganization of neural networks （inducing cortico-cortical functional connectivity and subcortical functional connectivity），adjustment of afferent nerve fiber sensitivity，alteration of neurotransmitter levels，and effects on neuroimmune interactions. …”
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Dopamine Suppresses Osteogenic Differentiation of Rat Bone Marrow-Derived Mesenchymal Stem Cells via AKT/GSK-3β/β-Catenin Signaling Pathway by Zhili Kuang, Zheng Chen, Shaoqin Tu, Zhihui Mai, Lin Chen, Xiaoning Kang, Xiaochuan Chen, Jiaming Wei, Yuxuan Wang, Yun Peng, Hong Ai

“…Dopamine, a pivotal neurotransmitter, plays a crucial role in sympathetic regulation, hormone secretion, immune activation, and blood pressure regulation. …”
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Hepatic encephalopathy: pathogenesis, clinical presentation, diagnostics, treatment by Ch. S. Pavlov, I. V. Damulin, V. T. Ivashkin

“…Some believe, that the leading part is played by the effect of hyperammoniemia on neuronal functions; the others give major importance to the change in aminoacid spectrum and neurotransmitter disorders; the third give the most attention to elevation of mercaptan concentration and level of shortchain fatty acids, change of GABA-benzodiazepine complex function. …”
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Lactobacillus rhamnosus: An emerging probiotic with therapeutic potential for depression by Jing Feng, Qiuyu Cen, Yanru Cui, Xiaomin Hu, Min Li, Linjie Wang, Juanfang Wei, Nianyi Sun, Junyu Wang, Anren Zhang

“…This review preliminarily explores the clinical significance of Lactobacillus rhamnosus in the treatment of depression and summarizes the potential mechanisms by which Lactobacillus rhamnosus treats depression, including its regulation of gut microbiota, alterations in gene expression, improvement of intestinal barrier function, maintenance of neurotransmitter balance, suppression of inflammatory responses, modulation of the immune system, coping with oxidative stress, and optimization of metabolic processes. …”
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Abnormal neurobehaviour and impaired memory function as a consequence of Toxocara canis- as well as Toxocara cati-induced neurotoxocarosis. by Elisabeth Janecek, Patrick Waindok, Marion Bankstahl, Christina Strube

“…Interestingly, enhanced grooming behaviour was observed exclusively in T. cati-infected mice, indicating a possible role of neurotransmitter dysregulation. Reduced exploratory behaviour and memory impairment was observed in both infection groups with delayed onset and less severe progression in T. cati- compared to T. canis-infected mice.…”
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Role of Ketamine in the Treatment of Psychiatric Disorders by Sahar Derakhshanian, Maxine Zhou, Alexander Rath, Rachel Barlow, Sarah Bertrand, Caroline DeGraw, Christopher Lee, Jamal Hasoon, Alan D. Kaye

“…The illness is complex and combines genetic, pathophysiologic, and environmental factors that combine to negatively affect neurotransmitter balance in the brain. Additional evidence suggests dysregulation of the hypothalamic-pituitary (HPA) axis, brain-derived neurotrophic factor (BDNF), vitamin D levels, and involvement of pro-inflammatory markers. …”
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Fumonisin B1 neurotoxicity: Preclinical evidence, biochemical mechanisms and therapeutic strategies by Blessing A. Obafemi, Isaac A. Adedara, Cássia Pereira Delgado, Olabisi T. Obafemi, Michael Aschner, Joao B.T. Rocha

“…Studies have also shown that neurotoxicity due to FB1 involves dysregulation of several biochemical events in the brain, such as induction of oxidative stress and inflammation, mitochondrial dysfunction and associated programmed cell death, inhibition of acetylcholinesterase and alteration of neurotransmitter levels, decreased activity of Na+K+ ATPase, as well as disruption of blood-brain barrier. …”
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Fucoxanthin Inhibits the NMDA and AMPA Receptors Through Regulating the Calcium Response on Substantia Gelatinosa Neurons of the Trigeminal Subnucleus Caudalis in Juvenile Mice by Nhung Ha Thuy Le, Seon Ah Park, Yu Mi Kim, Dong Kuk Ahn, Won Jung, Seong Kyu Han

“…Meanwhile, substantia gelatinosa (SG) neurons of the trigeminal subnucleus caudalis (Vc), a pivotal site in regulating orofacial nociceptive transmission via Aδ and C primary afferent fibers, majorly utilize glutamate as the principal excitatory neurotransmitter. Fucoxanthin (FCX), a carotenoid pigment extracted from brown seaweed, possesses various pharmaceutical properties including neuroprotective effect in multiple neuronal populations. …”
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Sexual dimorphism in the response to antidepressant therapy: Biological basis and clinical implications declaration of competing interests author contributions by Nedeljković Jelena, Stanić Dušanka, Petrović Jelena, Ivanović Ana, Ilić Miloš, Nikolašević-Stojković Gorana, Pejušković Bojana, Pešić Vesna

“…Neurobiological studies highlight gender-specific differences in brain structure and function, as well as in neurotransmitter systems, which may impact treatment efficacy and response variability. …”
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Evaluation of the Tyrosine and Dopamine Serum Levels in Experimental Infected BALB/c Mice with Chronic Toxoplasmosis by Mehdi Mirzaeipour, Fattaneh Mikaeili, Qasem Asgari, Mohammad Nohtani, Sajad Rashidi, Mohammad Saleh Bahreini

“…Toxoplasma parasite alters the transduction of neurotransmitter signals and leads to changes in the level of brain neurotransmitters including tyrosine and dopamine, so behavior changes can occur in infected hosts. …”
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Acupuncture for Parkinson’s Disease: Efficacy Evaluation and Mechanisms in the Dopaminergic Neural Circuit by Yadan Zhao, Zichen Zhang, Siru Qin, Wen Fan, Wei Li, Jingyi Liu, Songtao Wang, Zhifang Xu, Meidan Zhao

“…It has also been found that acupuncture can protect dopaminergic neurons from degeneration via antioxidative stress, anti-inflammatory, and antiapoptotic pathways as well as modulating the neurotransmitter balance in the basal ganglia circuit. …”
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C-Reactive Protein As A Response Indicator In Drug-Naïve Patients With Major Depressive Disorder: A Hospital-Based Study by Ather Muneer, Nargis Munir, Nadia Shams, Mirza Inam, Usman Ghani, Neelam Ayub

“… Abstract Objective: C-reactive protein (CRP) is an indicator of the inflammatory process in the body, and is associated with the pathogenesis of depression through its purported effect on neurotransmitter function in the brain. Current research aims to study the relationship between the levels of CRP and the rate of remission of major depressive disorder with first-line antidepressant therapy. …”
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