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    Advances in fear memory erasure and its neural mechanisms by Wenbo Guo, Xibo Wang, Xibo Wang, Zihan Zhou, Zihan Zhou, Yuhui Li, Yuhui Li, Yani Hou, Keyan Wang, Ruyuan Wei, Xiaoyu Ma, Hao Zhang

    Published 2025-01-01
    “…Therefore, erasing pathological fear memories in vivo is a crucial topic in neuroscience for understanding the nature of memories and treating clinically relevant diseases.Main textThis article reviews recent studies on fear memory erasure, erasure of short- and long-term memory, fear memory erasure and neuroplasticity, the neural circuitry and molecular mechanisms of fear memory erasure, and the roles of engram cells and perineuronal nets in memory erasure.ConclusionResearch on the mechanism of memory erasure is limited, and a plausible explanation for the essential difference between memory erasure and memory extinction still needs to be provided. …”
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