Showing 81 - 100 results of 616 for search '"neuroprotection"', query time: 0.06s Refine Results
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    Anti-Inflammatory and Neuroprotective Role of Natural Product Securinine in Activated Glial Cells: Implications for Parkinson’s Disease by Dmitri Leonoudakis, Anand Rane, Suzanne Angeli, Gordon J. Lithgow, Julie K. Andersen, Shankar J. Chinta

    Published 2017-01-01
    “…In this study, we explored the underlying mechanisms of neuroprotection elicited by securinine, particularly its anti-inflammatory effects in glial cells. …”
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    Neuroprotective effects of arbutin against oxygen and glucose deprivation-induced oxidative stress and neuroinflammation in rat cortical neurons by Tan Jingjing, Yadav Manoj Kumar, Devi Sushma, Kumar Manish

    Published 2022-03-01
    “…In this study, the neuroprotective potential of arbutin (100 µmol L−1) pre-treatment and post-treatment against oxygen/ glucose deprivation (OGD) and reoxygenation (R) induced ischemic injury in cultured rat cortical neurons was explored. …”
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    Obtention of stable neuroprotective extracts from orange by-products by gas-expanded liquids extraction (GXLE) and liposomal microencapsulation by Victor M. Amador-Luna, Lidia Montero, Pablo Mendoza-Orbaneja, Elena Ibáñez, Miguel Herrero

    Published 2025-03-01
    “…In this contribution, a process combining gas-expanded liquids extraction together with a novel microencapsulation protocol is studied with the aim to recover and stabilize neuroprotective compounds from orange by-products. Both process conditions were optimized by means of experimental designs. …”
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    Article
  11. 91

    Glycyrrhizin as a potential disease-modifying therapy for epilepsy: insights into targeting pyroptosis to exert neuroprotective and anticonvulsant effects by Lei Wei, Sijie Ou, Youshi Meng, Lanfeng Sun, Lin Zhang, Yuling Lu, Yuan Wu

    Published 2025-01-01
    “…Molecular experiments indicated that glycyrrhizin may regulate pyroptosis through mediation of the high mobility group box 1 (HMGB1)/Toll-like receptor 4 (TLR4)/nuclear factor kappa-B (NF-κB) signaling pathway.ConclusionGlycyrrhizin exerts neuroprotective and anticonvulsant effects in epilepsy by regulating pyroptosis via the HMGB1/TLR4/NF-κB signaling pathway, offering novel insights into its potential as a DMT for epilepsy.…”
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  12. 92

    Neuroprotective effects of kudzu root extract alone and in combination with maqui berry extract in streptozotocin-induced neuropathic pain by Chetana Shewale, Aman Upaganlawar, Prithviraj Deoda, Sakshi Ingale, Manoj Mahajan, Chandrashekhar Upasani

    Published 2024-12-01
    “…We evaluated the neuroprotective effects of kudzu root extract and maqui berry extract on streptozotocin (STZ)-induced DN in rats. …”
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    Therapeutic Role of Protein Tyrosine Phosphatase 1B in Parkinson’s Disease via Antineuroinflammation and Neuroprotection In Vitro and In Vivo by Chien-Wei Feng, Nan-Fu Chen, Te-Fu Chan, Wu-Fu Chen

    Published 2020-01-01
    “…Besides, we knocked down and overexpressed PTP1B in the SH-SY5Y cells to confirm its role in neuroprotection. We also verified the effect of suramin in the zebrafish PD model. …”
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    Article
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    Artificial intelligence-enabled discovery of a RIPK3 inhibitor with neuroprotective effects in an acute glaucoma mouse model by Xing Tu, Zixing Zou, Jiahui Li, Simiao Zeng, Zhengchao Luo, Gen Li, Yuanxu Gao, Kang Zhang, Jing Ni

    Published 2025-01-01
    “…It was also observed that the neuroprotective effects of HG9-91-01 were highly correlated with the inhibition of PANoptosis (apoptosis, pyroptosis, and necroptosis). …”
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    LFA-1: A potential key player in microglia-mediated neuroprotection against oxygen-glucose deprivation in vitro. by Robin Jansen, Marc Pawlitzki, Michael Gliem, Sven G Meuth, Stefanie Schreiber, Michael-W Görtler, Jens Neumann

    Published 2025-01-01
    “…For the last 38 years, all neuroprotective agents for patients with ischemic stroke have failed in clinical trials. …”
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