Computational screening, synthesis and neuroprotective evaluation of small molecule for the treatment of alzheimer's disease by Nerlis Pajaro-Castro, Elkin Torres-Sierra, Edwar Cortes-Gonzalez, Margaret Paternina, Erwin Camacho, Pedro Blanco

“…Cytotoxicity and neuroprotective effects were assessed using the MTT assay in the presence of the Aβ25-35 peptide. …”
Get full text

Neuroprotective Effects of Collagen-Glycosaminoglycan Matrix Implantation following Surgical Brain Injury by Jia-Hui Chen, Wei-Cherng Hsu, Kuo-Feng Huang, Chih-Huang Hung

“…The present study was conducted to further examine the potential neuroprotective effects of collagen-glycosaminoglycan (CG) matrix implantation following neurosurgery. …”
Get full text

Medicinal plants with neuroprotective potential in East African countries: A systematic review by Ibe Michael Usman, Ekom Monday Etukudo, Elna Owembabazi, Wusa Makena, Augustine Oviosun, Makeri Danladi, Vivian Ojiakor, Patrick Maduabuchi Aja, Emeka Anyanwu, Yanurkis Duranones Rosales, Mario Edgar Fernandez Diaz, Josiah Ifie, Ismahil Adekunle Adeniyi, Ilemobayo Victor Fasogbon, Victor Bassey Archibong

Subjects: Get full text

The crucial role of 5hmC in neuroprotection and repair after cerebrovascular injury by Yanina Tsenkina

“…The discussion delves into the dynamic interaction between hydroxymethylation and important pathways in neuroprotection, such as the modulation of excitotoxicity and cellular metabolism, resolution of inflammation, and mitigation of oxidative stress. …”
Get full text

Neuroprotective Effects of Metformin and Berberine in Lipopolysaccharide-Induced Sickness-Like Behaviour in Mice by Triveni Kodi, Sharanya Praveen, Sravan Kumar Paka, Runali Sankhe, Adarsh Gopinathan, Nandakumar Krishnadas, Anoop Kishore

Get full text

Enhanced Neuroprotective Effects of Coadministration of Tetrandrine with Glutathione in Preclinical Model of Parkinson’s Disease by Xiang-Yun Li, Guang-Hai Mei, Qiang Dong, Yu Zhang, Zhuang-Li Guo, Jing-Jing Su, Yu-Ping Tang, Xue-Hong Jin, Hou-Guang Zhou, Yan-Yan Huang

“…In this study we examined the influence of tetrandrine (Tet) on the neuroprotective effects of glutathione (GSH) in the 6-hydroxydopamine- (6-OHDA-) lesioned rat model of Parkinson’s disease (PD). …”
Get full text

Artemisinin Stimulates Neuronal Cell Viability and Possess a Neuroprotective Effect In Vitro by Sergey A. Pukhov, Alexey V. Semakov, Nadezhda E. Pukaeva, Olga A. Kukharskaya, Tatyana V. Ivanova, Viktoriya S. Kryshkova, Sergey O. Bachurin, Michail S. Kukharsky

Subjects: Get full text

Neuroplasticity and Neuroprotective Effect of Treadmill Training in the Chronic Mouse Model of Parkinson’s Disease by Ewelina Palasz, Wiktor Niewiadomski, Anna Gasiorowska, Anna Mietelska-Porowska, Grazyna Niewiadomska

“…From these results one may conclude that early and late-onset training schedules were equipotent in their neuroprotective effect and that the mechanism of neuroprotection was similar. …”
Get full text

Exploring the Antioxidant and Neuroprotective Potential of Muscari armeniacum: Phenolic Profiling and Enzyme Inhibition by Fevzi Topal, Firat Yılmaz, Meryem Topal, Ahmed Menevşeoğlu

Get full text

In vitro neuroprotective potentials of aqueous and methanol extracts from Heinsia crinita leaves by Ganiyu Oboh, Esther E. Nwanna, Sunday I. Oyeleye, Tosin A. Olasehinde, Opeyemi B. Ogunsuyi, Aline A. Boligon

“…This study was designed to determine the neuroprotective potentials of aqueous and methanol extracts from Heinsia crinita leaves in vitro. …”
Get full text

Inhibition of Cathepsin S Produces Neuroprotective Effects after Traumatic Brain Injury in Mice by Jianguo Xu, Handong Wang, Ke Ding, Xinyu Lu, Tao Li, Jiawei Wang, Chunxi Wang, Jian Wang

Get full text

Effects of exercise training on nigrostriatal neuroprotection in Parkinson’s disease: a systematic review by Shahid Ishaq, Iqbal Ali Shah, Shin-Da Lee, Shin-Da Lee, Bor-Tsang Wu

Subjects: Get full text

Phenols from Vaccinium dunalianum Wight: Secondary Mass Spectrometry Fragmentation and Neuroprotective Effect by ZHOU Tang, WANG Ji, QIAO Wenhao, LIN Zhiqi, ZHU Hongbo, CHANG Yue, HU Weiyan, ZHANG Rongping, CHEN Xinglong

Subjects: “…vaccinium dunalianum wight; phenolic compounds; secondary mass spectrometry fragmentation; neuroprotective effect…”
Get full text

Insights on the molecular mechanism of neuroprotection exerted by edible bird’s nest and its bioactive constituents by Weiyi Chu, Chia Wei Phan, Seng Joe Lim, Abdul Salam Babji

Subjects: Get full text

Neuroprotective and Neurorestorative Processes after Spinal Cord Injury: The Case of the Bulbospinal Respiratory Neurons by Anne Kastner, Valéry Matarazzo

“…The rodent respiratory system is therefore a relevant model to investigate the neuroplastic and neuroprotective mechanisms that will trigger such phrenic motoneurons reactivation by supraspinal pathways. …”
Get full text

Isoforsythiaside confers neuroprotection against Alzheimer’s disease by attenuating ferroptosis and neuroinflammation in vivo and in vitro by Chunyue Wang, Hongbo Jiang, Honghan Liu, Shanshan Chen, Hangyu Guo, Shuoshuo Ma, Weiwei Han, Yu Li, Di Wang

“…The purpose of this study was to explore the anti-ferroptosis and anti-neuroinflammatory properties of IFY-mediated neuroprotection. In APP/PS1 mice, erastin-damaged HT22 cells, and LPS-exposed BV2 cells, the neuroprotective effects against ferroptosis and neuroinflammation were investigated using immunohistochemistry, label-free proteomics, western blot, ELISA, MTT, fluorescence, and TEM. …”
Get full text

Exploring Azithromycin’s Neuroprotective Role in Traumatic Brain Injury: Insights into Cognitive and Motor Recovery and Neuroinflammatory Modulation by Mohannad A. Almikhlafi, Nehad A. Abdallah, Aakash Kumar, Tarun Sharma, Zuber Khan, Haifa A. Fadil, Sultan Althagfan, Ahmed K. B. Aljohani, Sara A. Almadani, Samar F. Miski, Tahani Saeedi, Rayan S. Alharbi, Abdulrahman M. Al-Harthe, Mohammed H. Alsubhi, Hanaa Wanas, Ahmed Aldhafiri, Sidharth Mehan, Hossein M. Elbadawy

Subjects: Get full text

Neuroprotective Efficacy of <i>Astragalus mongholicus</i> in Ischemic Stroke: Antioxidant and Anti-Inflammatory Mechanisms by Yongjae Hong, Geon Ko, Yeong-Jae Jeon, Hyeon-Man Baek, Juni Lee, Donghun Lee, Jieun Park, Jaehong Kim, Keun-A Chang

“…Additionally, AM increased neuroprotective metabolites levels, reduced gliosis, and decreased oxidative stress, as evidenced by reduced inducible nitric oxide synthase (iNOS). …”
Get full text

Retraction: GDNF-Transfected Macrophages Produce Potent Neuroprotective Effects in Parkinson's Disease Mouse Model. by PLOS ONE Editors

Get full text

A combination of topical and systemic administration of brimonidine is neuroprotective in the murine optic nerve crush model. by Ruta Maciulaitiene, Giedrius Kalesnykas, Dainius Haroldas Pauza, Ingrida Januleviciene

“…Brimonidine is an intraocular pressure-lowering drug with reported neuroprotective properties. This study aimed to compare the neuroprotective effects of topical and intraperitoneal (IP) brimonidine on RGCs from different retinal segments in a murine optic nerve crush (ONC) model.…”
Get full text