Gastrodin Suppresses the Amyloid β-Induced Increase of Spontaneous Discharge in the Entorhinal Cortex of Rats by Peng-zhi Chen, Hui-hui Jiang, Bo Wen, Shuan-cheng Ren, Yang Chen, Wei-gang Ji, Bo Hu, Jun Zhang, Fenglian Xu, Zhi-ru Zhu

“…Our study suggested that GAS may provide neuroprotective effects on Aβ1−42-induced hyperactivity in EC neurons of rats.…”
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Bioactive compounds from Chinese herbal plants for neurological health: mechanisms, pathways, and functional food applications by Wang Meng, Wang Chao, Zhao Kaiwei, Ma Sijia, Sang Jiajia, Xu Shijie

“…The review highlights the neuroprotective properties of flavonoids, alkaloids, polysaccharides, and polyphenols found in key TCM herbs such as Scutellaria baicalensis, Salvia miltiorrhiza, Ligusticum chuanxiong, and Gastrodia elata. …”
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Dexmedetomidine to Help Nerve Regeneration in a Rat Sciatic Nerve Injury Model by Wook Jeong, Hsichiang Kung, Chia Chi Cheng, Changwoo Lim, Min Jung Jung, Jaeho Lee, Doo Sik Kim, Yusom Shin

“…Several studies have shown that dexmedetomidine (DXM), a selective α2-adrenoceptor agonist, also has neuroprotective effects. However, its effect on impaired peripheral nerve regeneration has not been studied. …”
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Peptidoglycan recognition protein PGRP-5 is involved in immune defence and neuro-behavioral disorders in zebrafish embryos. by Xi Li, Guanghua Xiong, Manni Luo, Siwan Mao, Ruiying Zhang, Ziwei Meng, Juan Li, Xinjun Liao

“…Finally, incubation of zebrafish embryos with anti-inflammatory and neuroprotective agents (10 μM Minocycline) can partially rescue the DrPGRP5-regulated locomotor behavior. …”
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Cannabis oil in treating Parkinson’s disease: improvement of motor and non-motor symptoms: a case report by C. T. M. I. Issa, R. D. Castro, K. L. G. D. Albuquerque

“…Further studies are needed to elucidate these results and the mechanisms of action of cannabinoids through which they exert possible neuroprotective and neuroreparative effects. These compelling results suggest that cannabis oil may offer a valuable and effective therapeutic option for individuals with Parkinson's disease.…”
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EFFECT OF Zanthoxylum acanthopodium DC EXTRACT ON THE INCREASE OF BRAIN CELLS IN THE SUBSTANTIA NIGRA OF WISTAR RATS THAT ARE ROTENONE-INDUCED by Shalli hafizha, Binarwan Halim, Linda Chiuman

“…Oxidative stress, inflammation, and mitochondrial damage play a role in its pathogenesis. andaliman fruit (Zanthoxylum acanthopodium DC), rich in alkaloids and flavonoids, has potential as an antioxidant with neuroprotective effects. The purpose of the study was to determine the effect of andaliman fruit extract (Zanthoxylum acanthopodium DC) on the increase of brain cells in the substantia nigra of rotenone-induced Wistar rats as a Parkinson's model. …”
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Antioxidant and Neuroproliferative Effects of THL-3-PTD5 Peptide Derived from Hydramacin-1 Antimicrobial Peptide by Ping-Chien Lee, Ching-Chun Lin, Hui-Hsuan Hsu, Feng-Di T. Lung

“…However, it did not exhibit neuroprotective effects under in vitro conditions of oxidative stress induced by an exogenous oxidizing agent. …”
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Decreased Hsp90 activity protects against TDP-43 neurotoxicity in a C. elegans model of amyotrophic lateral sclerosis. by Laura Garcia-Toscano, Heather N Currey, Joshua C Hincks, Jade G Stair, Nicolas J Lehrbach, Nicole F Liachko

“…We also observe that the neuroprotective effect due to HSP-90 dysfunction does not involve direct regulation of proteasome activity in C. elegans. …”
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Bauhinia coccinea extract prevents memory loss induced by scopolamine through activation of antiapoptotic and antioxidant pathways in mice by Eunjin Sohn, Bu-Yeo Kim, Yu Jin Kim, Joo-Hwan Kim, Soo-Jin Jeong

“…Nissl staining and immunohistochemistry for NeuN showed that EEBC exerted neuroprotective effects in SCO-injected mice brains. Moreover, EEBC significantly reduced the number of terminal deoxynucleotidyl transferase dUTP nick end labeling-positive apoptotic cells increased by SCO treatment. …”
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Impact of glaucoma and glaucoma surgery on quality of life by V.P. Erichev, A.V. Volzhanin

“…</i> </p> <p> <i><b>Keywords</b>: quality of life, glaucoma, trabeculectomy,&nbsp; minimally invasive glaucoma surgery, neuroprotective therapy.</i> </p> <p> <i><b>For citation: </b>Erichev V.P., Volzhanin A.V. …”
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Investigation of biometabolites and novel antimicrobial peptides derived from promising source Cordyceps militaris and effect of non-small cell lung cancer genes computationally. by Muhammad Afzal, Mai Abdel Haleem A Abusalah, Neelum Shehzadi, Muhammad Absar, Naveed Ahmed, Sarmir Khan, Yalnaz Naseem, Noshaba Mehmood, Kirnpal Kaur Banga Singh

“…It interacts favorably with the active site of RET gene of NSCLC and is neuroprotective and hepatoprotective.…”
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Shaoyao-Gancao Decoction Promoted Microglia M2 Polarization via the IL-13-Mediated JAK2/STAT6 Pathway to Alleviate Cerebral Ischemia-Reperfusion Injury by Juanjuan Lu, Jie Wang, Long Yu, Rong Cui, Ying Zhang, Hanqing Ding, Guofeng Yan

“…There was thus a hypothesis that SGD could exert an anti-inflammatory and neuroprotective effect by activating IL-13 to induce microglia polarization towards M2 phenotype, and the purpose of this study was to explore the influence of SGD on microglia phenotype switching and its possible mechanism. …”
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Pigment Epithelium-Derived Factor-Loaded PEGylated Nanoparticles as a New Antiangiogenic Therapy for Neovascularization by Feng Zhao, Wenlei Fei, Zhouyue Li, Hanyang Yu, Lei Xi

“…Pigment epithelium-derived factor (PEDF) is a potent natural, endogenous inhibitor of neovascularization because of its antiangiogenic and neuroprotective benefits. However, its application is restricted by its instability and short half-life. …”
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Mechanism of Nerve Regeneration after Ischemic Stroke Induced by Exercise Intervention by TENG Lili, ZHANG Mei, SONG Wenjing, ZHU Luwen

“…Based on the plasticity of the central nervous system, exercise intervention can play a neuroprotective role in the brain through multi-levels, multi-pathways and multi-targets, such as regulating synaptic budding, connection and transmission efficiency, improving the functional connection between regenerative axons and target cells, promoting angiogenesis and protecting the integrity of neurovascular units, regulating related inhibitory nerve regeneration factors, and inducing the expression of various nerve growth factors related to nerve regeneration and promoting the proliferation of neural stem cells, so as to participate in the regulation of central nervous rege-neration environment, and improve the damaged nerve function after ischemia.…”
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Superfoods and their impact on brain health: a systematic review by Raghupathi Niranjan Kumar, Haja Nazeer Ahamed

“…Conclusion After reviewing 95 papers, Ficus carica, Crocus sativus, Beta vulgaris, Murraya koenigii, Punica granatum, and Phoenix dactylifera are neuroprotective and therapeutic. Flavonoids in Ficus carica reduce anxiety and depression, whereas Punica granatum improves memory. …”
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Protective effect of silencing lncRNA HCP5 against brain injury after intracerebral hemorrhage by targeting miR-195-5p by Zhanhua Lu, Kun Huang

“…Moreover, HCP5 was found to sponge miR-195-5p, and inhibiting miR-195-5p could counteract the neuroprotective effects of silencing HCP5. Similar results were obtained in the in vitro experiments with BV2 cells. …”
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Development and Validation of a Stability-Indicating HPLC Method for the Simultaneous Determination of trans-Resveratrol and cis-Resveratrol in an Injectable Solution by Esmeralda Mota-Lugo, Mariana Dolores-Hernández, Elvia A. Morales-Hipólito, Iris A. Blanco-Alcántara, Hugo Cuatecontzi-Flores, Raquel López-Arellano

“…trans-Resveratrol, a phytochemical compound with antioxidant power and various therapeutic effects, such as cardioprotective, chemopreventive, and neuroprotective, among others, has disadvantages of poor solubility and limited stability, creating difficulties for the development of new strategies for its quantification. …”
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Protective Effects of Intravitreal Injection of the Rho-Kinase Inhibitor Y-27632 in a Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy (rAION) by Zuohuizi Yi, Liao Chen, Xiaoling Wang, Changzheng Chen, Yiqiao Xing

“…Intravitreal injection of Y-27632 had neuroprotective effects on ONH edema, RGC survival, and visual function preservation in rAION.…”
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Unravelling a mechanistic link between mitophagy defect, mitochondrial malfunction, and apoptotic neurodegeneration in Mucopolysaccharidosis VII by Nishan Mandal, Apurba Das, Rupak Datta

“…Interestingly, resveratrol treatment corrected the mitophagy defect and prevented ATP depletion in the CG2135−/− fly brain, providing an explanation for its neuroprotective effects. Collectively, our study reveals a pharmacologically targetable mechanistic link between mitophagy defect, mitochondrial malfunction, and apoptotic neurodegeneration in MPS VII.…”
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Research Progress on the Mechanism of Acupuncture Treatment of Ischemic Stroke Based on the Space Construction of Nerve-vascular Unit by LI Mengxing, WNAG Yu, LI Zhen, LIU Fang, SHI Kejian

“…The selection of targeted interventions among many targets could provide a direction to elucidate the possible material basis and effective target of acupuncture to reduce cerebral ischemic injury.ConclusionThe mechanism of acupuncture treatment of cerebral ischemia is closely related to NVU, which plays a synergistic neuroprotective role by bidirectional regulation of NVU spatial architecture, and it is the key to promoting functional recovery after cerebral ischemia.…”
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