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1941
The impact of glycolysis on ischemic stroke: from molecular mechanisms to clinical applications
Published 2025-01-01“…However, in the ischemia–reperfusion state, neuronal cells show a particular reliance on aerobic glycolysis. …”
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1942
Procesamiento de bases de datos escolares por medio de redes neuronales artificiales
Published 2020-01-01“…En este artículo se estudia este problema con el uso de tres modelos de red neuronal. Los resultados evidencian la capacidad de estos modelos para clasificar con un porcentaje de acierto superior a 95% las tendencias en los estudiantes utilizando principalmente datos cualitativos.…”
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1943
Forecast of Chaotic Series in a Horizon Superior to the Inverse of the Maximum Lyapunov Exponent
Published 2018-01-01“…The delay time and the global dimension are employed as parameters in the models of forecast of artificial neuronal networks (ANN) and support vector machine (SVM). …”
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Article -
1944
Formulated citrus peel extract gold lotion improves cognitive and functional recovery from traumatic brain injury (TBI) in rats
Published 2020-09-01“…The mechanisms probably due to that GL could not only reduce the associated damage markers including GFAP, OX-42, TNF-α, COX-2, NF-κB and TLR4 but also promote the expression of VEGF which is responsible for protecting neuronal cells in the injury area. These findings revealed that GL could be a promising preparation for TBI prevention.…”
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1945
Therapeutic Potentials of Synapses after Traumatic Brain Injury: A Comprehensive Review
Published 2017-01-01“…Second, we briefly describe several key synaptic proteins involved in neuroplasticity, which may be novel neuronal targets for specific intervention. Third, we address therapeutic interventions in association with synapses after TBI. …”
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1946
The mitochondria as a potential therapeutic target in cerebral I/R injury
Published 2025-01-01“…However, reperfusion can induce neuronal death, known as cerebral reperfusion injury, for which effective therapies are lacking. …”
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Article -
1947
Linking Neuroinflammation and Neurodegeneration in Parkinson’s Disease
Published 2018-01-01“…Nevertheless, several questions remain unanswered regarding the role of misfolded protein aggregates and the cause of neuronal cell death. Recently, it has been postulated that neuroinflammatory processes might play a crucial role in the pathogenesis of PD. …”
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1948
Resonant song recognition and the evolution of acoustic communication in crickets
Published 2025-02-01“…Of the three minimal models tested, only a single-neuron model with an oscillating membrane could explain this unusual behavior. …”
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1949
The Roles of Insulin-Like Growth Factor 2 mRNA-Binding Protein 2 in Cancer and Cancer Stem Cells
Published 2018-01-01“…IGF2BP2 represents the least understood member of this family of RBPs; however, it has been reported to participate in a wide range of physiological processes, such as embryonic development, neuronal differentiation, and metabolism. Its dysregulation is associated with insulin resistance, diabetes, and carcinogenesis and may potentially be a powerful biomarker and candidate target for relevant diseases. …”
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Article -
1950
Investigating the impact of microbiome-changing interventions on food decision-making: MIFOOD study protocol
Published 2025-01-01“…However, causal evidence on how these “bottom-up” and “top-down” processes affect food decision-making and neuronal correlates in humans is still scarce. In addition, microbiome, and gut-brain-axis-related mediating mechanisms remain unclear. …”
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Article -
1951
CEST imaging combined with 1H-MRS reveal the neuroprotective effects of riluzole by improving neurotransmitter imbalances in Alzheimer’s disease mice
Published 2025-01-01“…At the study endpoint, immunohistochemistry, Nissl staining, and Western blot were used to evaluate the brain pathology, neuronal survival, and protein expression. Results GluCEST, GABACEST and 1H-MRS consistently revealed higher levels of Glu and GABA in the brain of riluzole-treated AD mice compared to untreated controls, which were associated with improvements in spatial learning and memory. …”
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Article -
1952
Control of Linear-Threshold Brain Networks via Reservoir Computing
Published 2024-01-01“…We illustrate the versatility of this setup in two applications: selective recruitment and inhibition of neuronal populations for goal-driven selective attention, and network intervention for the prevention of epileptic seizures.…”
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Article -
1953
PyMem: A Graphical User Interface Tool for Neuromemristive Hardware–Software Co-Design
Published 2024-01-01“…Memristor-based hardware architectures is a promising approach that naturally mimics the switching behavior of the neuron models. However, to build complex neural systems, it is a tedious process to select the right memristor models and architectures that are suitable to be used in a range of realistic conditions. …”
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1954
Modeling sacsin depletion in Danio Rerio offers new insight on retinal defects in ARSACS
Published 2025-02-01“…While two murine models replicate the phenotypic and neuronal features observed in patients, no retinal phenotype has been described so far. …”
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Article -
1955
Using Electrocardiogram Signal Features and Heart Rate Variability to Predict Epileptic Attacks
Published 2025-01-01“…Since the increase in neuronal activity during an epileptic attack affects the voluntary nervous system, and the voluntary nervous system also affects the heart rate variability, it can be concluded that seizures can be predicted by monitoring heart rate variability. …”
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Article -
1956
Combination Treatment of C16 Peptide and Angiopoietin-1 Alleviates Neuromyelitis Optica in an Experimental Model
Published 2018-01-01“…Moreover, NMO may cause secondary complement-dependent cytotoxicity (CDC), leading to oligodendrocyte and neuronal damage. In this study, a rodent NMO model, showing typical NMO pathogenesis, was induced with NMO-IgG from patient serum and human complement. …”
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1957
Visual experience orthogonalizes visual cortical stimulus responses via population code transformation
Published 2025-02-01“…We measured orientation tuning in 4,000-neuron populations of mouse V1 before and after training on a visuomotor task. …”
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1958
Development of a Cell-Based Functional Assay for the Detection of Clostridium botulinum Neurotoxin Types A and E
Published 2013-01-01“…Here, we describe a cell-based assay utilizing a fluorescence reporter construct expressed in a neuronal cell model to study toxin activity in situ. …”
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Article -
1959
Connecting genomic results for psychiatric disorders to human brain cell types and regions reveals convergence with functional connectivity
Published 2025-01-01“…By integrating genomic insights from genome-wide association studies with a comprehensive single-cell transcriptomic atlas of the adult human brain, we prioritized specific neuronal clusters significantly enriched for the SNP-heritabilities for schizophrenia, bipolar disorder, and major depressive disorder along with intelligence, education, and neuroticism. …”
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1960
Neuroprotection and Stroke Rehabilitation: Modulation and Enhancement of Recovery
Published 2006-01-01“…This review discusses mechanisms of neuronal injury after brain ischemia and the attempts to study neuroprotection options based on such mechanisms. …”
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