Case report: Significant lesion reduction and neural structural changes following ibogaine treatments for multiple sclerosis by David Qixiang Chen, José Adalberto Inzunza Domínguez, Juan Manuel Valle Uzeta, Abhiram P. Pushparaj, Abhiram P. Pushparaj, Jonathan E. Dickinson

“…Multiple sclerosis (MS) is a debilitating neurodegenerative disease characterized by demyelination and neuronal loss. Traditional therapies often fail to halt disease progression or reverse neurological deficits. …”
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Fixed-Time Synchronization of Delayed Memristive Neural Networks with Discontinuous Activations by Hao Pu, Fengjun Li

“…In this paper, the fixed-time synchronization problem for a class of memristive neural networks with discontinuous neuron activation functions and mixed time-varying delays is investigated. …”
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A 17-Year-Old Female with Systemic Lupus Presents with Complex Movement Disorder: Possible Relationship with Antiribosomal P Antibodies by Muhammed Emin Özcan, Meriç Adil Altınöz, Hasan Hüseyin Karadeli, Talip Asil, Abdulkadir Koçer

“…Antiphospholipid antibodies are associated with movement disorders likely via aberrant neuronal stimulation. Antiribosomal P antibodies have been previously associated with neuropsychiatric disorders but their correlation with movement disorder was not previously established. …”
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High-resolution Cryo-EM Structure Determination of a-Synuclein—A Prototypical Amyloid Fibril by Juan Sanchez, Joshua Pierson, Collin Borcik, Chad Rienstra, Elizabeth Wright

“…The physiological role of a-synuclein (a-syn), an intrinsically disordered presynaptic neuronal protein, is believed to impact the release of neurotransmitters through interactions with the SNARE complex. …”
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Reduced white matter integrity and disrupted brain network in children with type 2 and 3 spinal muscular atrophy by Huirong Nie, Shasha Lan, Huan Wang, Pei Xiang, Mengzhen Yan, Yang Fan, Wanqing Shen, Yijuan Li, Wen Tang, Zhiyun Yang, Yujian Liang, Yingqian Chen

“…Abstract Background Spinal muscular atrophy (SMA) is caused by reduced expression of survival motor neuron (SMN) protein. Previous studies indicated SMA causes not only lower motor neuron degeneration but also extensive brain involvement. …”
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Co-administration of coenzyme Q10 and curcumin mitigates cognitive deficits and exerts neuroprotective effects in aluminum chloride-induced Alzheimer's disease in aged mice by Nida Rasheed, Hafiza Khushbakht Hussain, Zohabia Rehman, Azka Sabir, Waseem Ashraf, Tanveer Ahmad, Faleh Alqahtani, Imran Imran

“…Furthermore, CoQ10 and curcumin ameliorated AlCl3-induced neurotoxicity by preserving neuronal cytoarchitecture in both cortical and hippocampal regions. …”
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The sexually dimorphic expression of glutamate transporters and their implication in pain after spinal cord injury by Jennifer M. Colón-Mercado, Aranza I. Torrado-Tapias, Iris K. Salgado, José M. Santiago, Samuel E. Ocasio Rivera, Dina P. Bracho-Rincon, Luis H. Pagan Rivera, Jorge D. Miranda

“…The excitatory glutamate transporters are responsible for the reuptake of extracellular glutamate which makes them a critical target to prevent neuronal hyperexcitability and excitotoxicity. Our previous studies showed a sexually dimorphic therapeutic window for spinal cord injury after treatment with the selective estrogen receptor modulator tamoxifen. …”
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Evidence for direct dopaminergic connections between substantia nigra pars compacta and thalamus in young healthy humans by Giovanni Cirillo, Giuseppina Caiazzo, Federica Franza, Mario Cirillo, Michele Papa, Fabrizio Esposito

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Sarcopenia, a Neurogenic Syndrome? by Ping Kwan

“…Although the complete mechanism underlying the development of sarcopenia is still waiting to be elucidated, we propose in this article that the primary trigger of sarcopenia may be neurogenic in origin based on the intimate relationship between the nervous and muscular system, namely, the motor neuron and its underlying muscle fibers. Both of them are affected by the cellular environment and their physiological activity.…”
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Frontotemporal Dementia as a Possible Manifestation of Primary Lateral Sclerosis: A Case Report and Literature Review by Kevin Qosja, Nicole M. Absar, Allen T. Yu

“…Primary lateral sclerosis (PLS) is currently defined as a restricted phenotype of amyotrophic lateral sclerosis (ALS), a neurodegenerative disease with upper motor neuron (UMN) symptoms that causes slowly progressive spasticity. …”
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Neuroimaging Insights into Autism Spectrum Disorder: Structural and Functional Brain by Mahie Patil, Nofel Iftikhar, Latha Ganti

“…Postmortem research reveals cellular and synaptic changes, such as fewer Purkinje cells and altered neuron organization. These findings highlight the importance of studying the social brain network in ASD and suggest the need for more long-term, comprehensive studies. …”
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Regulatory mechanism of Reelin activity: a platform for exploiting Reelin as a therapeutic agent by Mitsuharu Hattori

“…Reelin is a secreted glycoprotein that was initially investigated in the field of neuronal development. However, in recent decades, its role in the adult brain has become increasingly important, and it is now clear that diminished Reelin function is involved in the pathogenesis and progression of neuropsychiatric and neurodegenerative disorders, including schizophrenia and Alzheimer’s disease (AD). …”
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Event-Triggered State Estimation for a Class of Delayed Recurrent Neural Networks with Sampled-Data Information by Hongjie Li

“…The main purpose is to estimate the neuron states through output sampled measurement; a novel event-triggered scheme is proposed, which can lead to a significant reduction of the information communication burden in the network; the feature of this scheme is that whether or not the sampled data should be transmitted is determined by the current sampled data and the error between the current sampled data and the latest transmitted data. …”
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Comparing P300 flashing paradigms in online typing with language models. by Nand Chandravadia, Shrita Pendekanti, Dustin Roberts, Robert Tran, Saarang Panchavati, Corey Arnold, Nader Pouratian, William Speier

“…The P300 Speller is a brain-computer interface system that allows victims of motor neuron diseases to regain the ability to communicate by typing characters into a computer by thought. …”
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Tutor Inteligente con reconocimiento y manejo de emociones para Matemáticas by Mari­a Luci­a Barron Estrada, Ramón Zatarain Cabada, Yasmín Hernández Pérez

“…El reconocimiento de emociones se lleva a cabo a través de expresiones faciales, lo cual se realiza por medio de una red neuronal artificial. La red social y el Sistema Tutor Inteligente con manejo afectivo han sido probados en escuelas públicas y privadas de la localidad, con resultados muy favorables.…”
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Bimelic Hirayama Disease: Clinical Dilemma Solved by Imaging by Shalabh Jain, Siddharth Yadav, Swarna Gupta, Ritu Gupta

“…On the basis of clinical examination, a provisional diagnosis of lower motor neuron type of symmetrical distal weakness due to heavy metal intoxication was kept. …”
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Impaired Functional Connectivity in the Prefrontal Cortex: A Mechanism for Chronic Stress-Induced Neuropsychiatric Disorders by Ignacio Negrón-Oyarzo, Francisco Aboitiz, Pablo Fuentealba

“…We propose that chronic stress impairs mechanisms involved in neuronal functional connectivity in the PFC that are required for the formation of adaptive representations for the execution of adaptive behavioral responses. …”
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Mitochondrial Dysfunction in Parkinson's Disease by P. C. Keane, M. Kurzawa, P. G. Blain, C. M. Morris

“…This paper aims to illustrate the considerable body of evidence linking mitochondrial dysfunction with neuronal cell death in the substantia nigra pars compacta (SNpc) of PD patients and to highlight the important need for further research in this area.…”
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Mitochondrial Dysfunction and Therapeutic Targets in Auditory Neuropathy by Baoyi Feng, Chenxi Jin, Zhenzhe Cheng, Xingle Zhao, Zhuoer Sun, Xiaofei Zheng, Xiang Li, Tingting Dong, Yong Tao, Hao Wu

“…Auditory neuropathies (AN) were proved to play a substantial role in SNHL recently, and spiral ganglion neuron (SGN) dysfunction is a dominant pathogenesis of AN. …”
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Modeling the Encephalopathy of Prematurity in Animals: The Important Role of Translational Research by Hannah C. Kinney, Joseph J. Volpe

“…Nevertheless, animal models that simultaneously address oligodendrocyte, neuronal, and axonal injury carry the potential to decipher shared mechanisms and synergistic treatments to ameliorate the global consequences of the encephalopathy of prematurity.…”
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