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1841
Effects of Cisplatin in Neuroblastoma Rat Cells: Damage to Cellular Organelles
Published 2012-01-01“…This paper aims to describe the morphological and functional changes of the Golgi apparatus and lysosomes during apoptosis induced in neuronal rat cells (B50) by cisplatin. The results obtained show that the cellular organelles are the target of cisPt, so their damage can induce cell death.…”
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1842
Wallerian degeneration: From mechanism to disease to imaging
Published 2025-01-01“…Initial studies suggested that the formation mechanism of WD is related to the nutrition of neuronal cell bodies to axons. However, with the wide application of transgenic mice in experiments, the latest studies have found that the mechanism of WD is related to axonal degeneration, myelin clearance and extracellular matrix. …”
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1843
The history and frontiers of clinic electroencephalography technology
Published 2024-12-01“…Electroencephalography (EEG), which can intuitively monitor and record the discharge activities of neuronal groups in the brain, is a crucial scientific and clinical diagnostic technique in the field of neuroscience. …”
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1844
Neuroprotective Effects of Stem Cells in Ischemic Stroke
Published 2017-01-01“…The underlying mechanism involved antiapoptosis, anti-inflammation, promotion of angiogenesis and neurogenesis, formation of new neural cells and neuronal circuitry, antioxidation, and blood-brain barrier (BBB) protection. …”
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1845
Advances in hydrogel for diagnosis and treatment for Parkinson’s disease
Published 2025-02-01“…Hydrogels are conspicuous in many therapeutic applications, including neuron regeneration, neuroprotection, and diagnosis. …”
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1846
Role of Microglia in CNS Autoimmunity
Published 2013-01-01“…The disease is characterized histologically by the infiltration of encephalitogenic TH1/TH17-polarized CD4+ T cells, B cells, and a plethora of myeloid cells, resulting in severe demyelination ultimately leading to a degeneration of neuronal structures. These pathological processes are substantially modulated by microglia, the resident immune competent cells of the CNS. …”
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1847
Paravertebral Burkitt's Lymphoma in a Child: An Unusual Presentation
Published 2012-01-01“…The association with elevated serum neuron specific enolase suggested at first the diagnosis of neuroblastoma, but the pathological examination revealed a Burkitt's lymphoma. …”
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1848
From Basic Visual Science to Neurodevelopmental Disorders: The Voyage of Environmental Enrichment-Like Stimulation
Published 2019-01-01“…Genes and environmental stimuli cooperate in the regulation of brain development and formation of the adult neuronal architecture. Genetic alterations or exposure to perturbing environmental conditions, therefore, can lead to altered neural processes associated with neurodevelopmental disorders and brain disabilities. …”
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1849
Contribution of Microglia-Mediated Neuroinflammation to Retinal Degenerative Diseases
Published 2015-01-01“…Retinal degenerative diseases are major causes of vision loss and blindness worldwide and are characterized by chronic and progressive neuronal loss. One common feature of retinal degenerative diseases and brain neurodegenerative diseases is chronic neuroinflammation. …”
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1850
The role of neurofilament light chain in the context of neurological disorders
Published 2020-12-01“… Neurofilament light chain (NFL) is a structural neuronal protein highly expressed in large myelinated axons. …”
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1851
An Interesting Case of Bilateral Facial Palsy due to Granulomatosis with Polyangiitis
Published 2021-01-01“…We are reporting a case of granulomatosis with polyangiitis, complicated by bilateral facial palsy due to lower motor neuron involvement of the facial nerve, which has responded well to immunosuppressive treatment, particularly rituximab. …”
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1852
A Quarter Century of Liver Transplantation: Learning from Livers
Published 1989-01-01“…Normal gallbladder motility in the denervated transplanted liver questions the role of neuronal influences on gallbladder function. Finally, experimental liver transplantation in animals has been used as a tool to study metabolic problems.…”
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1853
Sex reversal induced by 17β-estradiol may be achieved by regulating the neuroendocrine system of the Pacific white shrimp Penaeus vannamei
Published 2025-01-01“…The observed retardation in growth in the EM group may be attributed to the potential for neuronal damage and disruptions in the cell cycle and PI3K-Akt signaling pathways. …”
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1854
The feasibility study of natural pigments as food colorants and seasonings pigments safety on dried tofu coloring
Published 2018-09-01“…Furthermore, the results from the PC12 cell suggested that dietary exposure of methylglyoxal (<50 μM) in soy sauce did not affect neuron cellular morphology and cell cycle significantly. …”
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1855
Effect of ethanol extract of nigella sativa L seeds and propofol on BDNF protein level as neuroplasticity and neuroprotection of traumatic brain injury in rats [version 2; peer rev...
Published 2024-09-01“…Brain Derived Neurotrophic Factor (BDNF) is a neurotropin that functions as a neuron protective. Nigella sativa L is reported to have an antioxidant effect, administration of Nigella Sativa L to rats treated with ischemia-reperfusion brain injury. …”
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1856
Using RNA-Seq to Explore the Repair Mechanism of the Three Methods and Three-Acupoint Technique on DRGs in Sciatic Nerve Injured Rats
Published 2020-01-01“…GO function is enriched in the positive regulation of cell processes, ion binding, protein binding, neuron, response to pressure, response to metal ions, neuron projection, and other biological processes. …”
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1857
Potensi Terapi Fitokanabinoid Mayor dalam Pengobatan Cedera Otak Traumatik: sebuah Tinjauan Literatur Farmakologis
Published 2024-12-01“…These major phytocannabinoids are known to influence cannabinoid receptors (CB1 and CB2), which play roles in modulating inflammatory processes, reducing neuronal damage, improving motor and cognitive functions, and regulating recovery mechanisms in the blood-brain barrier and intracranial lymphatics. …”
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1858
Chitinase-3-like-1: a multifaceted player in neuroinflammation and degenerative pathologies with therapeutic implications
Published 2025-01-01“…This review explores the role of CHI3L1 in the pathogenesis of these disorders, with a focus on its contributions to neuroinflammation, immune cell infiltration, and neuronal degeneration. As a key regulator of neuroinflammation, CHI3L1 modulates microglia and astrocyte activity, driving the release of proinflammatory cytokines that exacerbate disease progression. …”
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1859
Generation and characterization of two induced pluripotent stem cell lines (ICGi052-A and ICGi052-B) from a patient with frontotemporal dementia with parkinsonism-17 associated wit...
Published 2024-11-01“…Frontotemporal dementia with parkinsonism-17 is a neurodegenerative disease characterised by pathological aggregation of the tau protein with the formation of neurofibrillary tangles and subsequent neuronal death. The inherited form of frontotemporal dementia can be caused by mutations in several genes, including the MAPT gene on chromosome 17, which encodes the tau protein. …”
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1860
Tau oligomers impair memory and synaptic plasticity through the cellular prion protein
Published 2025-01-01“…Abstract Deposition of abnormally phosphorylated tau aggregates is a central event leading to neuronal dysfunction and death in Alzheimer’s disease (AD) and other tauopathies. …”
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