Is There an Association between Bell Palsy in Pediatric Patients and COVID-19? by Mohamed E. El-Deeb, Saad Elzayat, Abeer Salamah, Ali Gamal, Shimaa Elgamal, Ahmed El-Sobki

“… Introduction Bell palsy (BP) is an acquired, idiopathic facial palsy linked to lower motor neuron malfunction of the seventh cranial nerve. Several studies have identified BP as one of the many neuropathies that coronavirus disease 2019 (COVID-19) patients have developed, while other studies disagree.…”
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Astrocyte-Derived Interleukin 11 Modulates Astrocyte–Microglia Crosstalk via Nuclear Factor-κB Signaling Pathway in Sepsis-Associated Encephalopathy by Dandan Zhu, Peng Wang, Xiyue Chen, Kaituo Wang, Yunsong Wu, Min Zhang, Jianhua Qin

“…Sepsis-associated encephalopathy (SAE) is a severe and frequent septic complication, characterized by neuronal damage as key pathological features. The astrocyte–microglia crosstalk in the central nervous system (CNS) plays important roles in various neurological diseases. …”
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Brain penetration of peripheral extracellular vesicles from Alzheimer's patients and induction of microglia activation by Hermine Counil, Rummenigge Oliveira Silva, Jean‐Michel Rabanel, Charlotte Zaouter, Mohamed Haddad, Mohamed Raâfet Ben Khedher, Davide Brambilla, Tamas Fülöp, Shunmoogum A. Patten, Charles Ramassamy

“…The passage of pEVs through the endothelial bEnd.3 cells was studied in a Transwell device with either neuronal or microglia cells seeded at the bottom of the well. …”
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Distinct roles of dentate gyrus and medial entorhinal cortex inputs for phase precession and temporal correlations in the hippocampal CA3 area by Siavash Ahmadi, Takuya Sasaki, Marta Sabariego, Christian Leibold, Stefan Leutgeb, Jill K. Leutgeb

“…Abstract The hippocampal CA3 subregion is a densely connected recurrent circuit that supports memory by generating and storing sequential neuronal activity patterns that reflect recent experience. …”
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The Insulin Regulatory Network in Adult Hippocampus and Pancreatic Endocrine System by Masanao Machida, Shin Fujimaki, Ryo Hidaka, Makoto Asashima, Tomoko Kuwabara

“…Hormonal signals from the pancreatic islets influence the regulation of energy homeostasis by the brain, and the brain in turn influences the secretions of the islets. Diabetes induces neuronal death in different regions of the brain especially hippocampus, causes alterations on the neuronal circuits and therefore impairs learning and memory, for which the hippocampus is responsible. …”
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Electrical Stimulation of the Ear, Head, Cranial Nerve, or Cortex for the Treatment of Tinnitus: A Scoping Review by Derek J. Hoare, Peyman Adjamian, Magdalena Sereda

“…For tinnitus, where the pathological neuronal activity might be associated with auditory and other areas of the brain, interventions using electromagnetic, electrical, or acoustic stimuli separately, or paired electrical and acoustic stimuli, have been proposed as treatments. …”
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Thiadiazoline- and Pyrazoline-Based Carboxamides and Carbothioamides: Synthesis and Inhibition against Nitric Oxide Synthase by Fabio Arias, M. Encarnación Camacho, M. Dora Carrión, Meriem Chayah, Miguel Romero, Juan Duarte, Miguel A. Gallo

“…In general, thiadiazolines (5a–e) inhibit preferentially the neuronal isoform; among them, 5a is the best nNOS inhibitor (74.11% at 1 mM, IC50 = 420 μM). …”
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Endothelial SHANK3 regulates tight junctions in the neonatal mouse blood-brain barrier through β-Catenin signaling by Yong-Eun Kim, Minseong Kim, Sunwhi Kim, Raham Lee, Yusuke Ujihara, Esther Magdalena Marquez-Wilkins, Yong-Hui Jiang, Esther Yang, Hyun Kim, Changhoon Lee, Changwon Park, Il Hwan Kim

“…Endothelium-specific Shank3 (eShank3) knockout (KO) neonatal mice exhibit male-specific BBB-hyperpermeability, reduced neuronal excitability, and impaired ultra-sonic communications. …”
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Multiscale Modeling Indicates That Temperature Dependent [Ca2+]i Spiking in Astrocytes Is Quantitatively Consistent with Modulated SERCA Activity by Niko Komin, Mahsa Moein, Mark H. Ellisman, Alexander Skupin

“…Changes in the cytosolic Ca2+ concentration ([Ca2+]i) are the most predominant active signaling mechanism in astrocytes that can modulate neuronal activity and is assumed to influence neuronal plasticity. …”
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E4F1 coordinates pyruvate metabolism and the activity of the elongator complex to ensure translation fidelity during brain development by Michela Di Michele, Aurore Attina, Pierre-François Roux, Imène Tabet, Sophie Laguesse, Javier Florido, Morane Houdeville, Armelle Choquet, Betty Encislai, Giuseppe Arena, Carlo De Blasio, Olivia Wendling, François-Xavier Frenois, Laura Papon, Lucille Stuani, Maryse Fuentes, Céline Jahannault Talignani, Mélanie Rousseau, Justine Guégan, Yoan Buscail, Pierrick Dupré, Henri-Alexandre Michaud, Geneviève Rodier, Floriant Bellvert, Hanna Kulyk, Carole Ferraro Peyret, Hugo Mathieu, Pierre Close, Francesca Rapino, Cédric Chaveroux, Nelly Pirot, Lucie Rubio, Adeline Torro, Tania Sorg, Fabrice Ango, Christophe Hirtz, Vincent Compan, Elise Lebigot, Andrea Legati, Daniele Ghezzi, Laurent Nguyen, Alexandre David, Claude Sardet, Matthieu Lacroix, Laurent Le Cam

“…Abstract Pyruvate metabolism defects lead to severe neuropathies such as the Leigh syndrome (LS) but the molecular mechanisms underlying neuronal cell death remain poorly understood. Here, we unravel a connection between pyruvate metabolism and the regulation of the epitranscriptome that plays an essential role during brain development. …”
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The Enteric Nervous System and Its Emerging Role as a Therapeutic Target by Mark A. Fleming, Lubaina Ehsan, Sean R. Moore, Daniel E. Levin

“…The gastrointestinal (GI) tract is innervated by the enteric nervous system (ENS), an extensive neuronal network that traverses along its walls. Due to local reflex circuits, the ENS is capable of functioning with and without input from the central nervous system. …”
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Oxidative Stress, DNA Damage, and c-Abl Signaling: At the Crossroad in Neurodegenerative Diseases? by Stefania Gonfloni, Emiliano Maiani, Claudia Di Bartolomeo, Marc Diederich, Gianni Cesareni

“…Recent reports show that aberrant c-Abl activation causes neuroinflammation and neuronal loss in the forebrain of transgenic adult mice. …”
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Cytokines and Chemokines at the Crossroads of Neuroinflammation, Neurodegeneration, and Neuropathic Pain by Geeta Ramesh, Andrew G. MacLean, Mario T. Philipp

“…The latter may mediate neuronal and glial cell injury and death through production of proinflammatory factors such as cytokines and chemokines. …”
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Recent Developments on Novel 2D Materials for Emerging Neuromorphic Computing Devices by Muhammad Hamza Pervez, Ehsan Elahi, Muhammad Asghar Khan, Muhammad Nasim, Muhammad Asim, Arslan Rehmat, Malik Abdul Rehman, Mohammed A. Assiri, Shania Rehman, Jonghwa Eom, Muhammad Farooq Khan

“…This comprehensive review provides an extensive study of the recent advancements in 2D materials‐based neuromorphic devices especially in multiterminal synaptic devices, two‐terminal synaptic devices, neuronal devices, and the integration of synaptic and neuronal devices. …”
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Inactivation of the CMAH gene and deficiency of Neu5Gc play a role in human brain evolution by Yuxin Liu, Jinhong Li, Qicai Liu

“…The inactivation of CMAH and the loss of endogenous Neu5Gc may have played a role in human brain evolution by affecting neural conduction, neuronal development, and aging.…”
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Guidance Cue Netrin-1 and the Regulation of Inflammation in Acute and Chronic Kidney Disease by Punithavathi Ranganathan, Riyaz Mohamed, Calpurnia Jayakumar, Ganesan Ramesh

“…One such paradigm exists in the developing nervous system, where neuronal migration is mediated by a balance between chemoattractive and chemorepulsive signals. …”
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Glycyrrhizin as a potential disease-modifying therapy for epilepsy: insights into targeting pyroptosis to exert neuroprotective and anticonvulsant effects by Lei Wei, Sijie Ou, Youshi Meng, Lanfeng Sun, Lin Zhang, Yuling Lu, Yuan Wu

“…These patients experience progressive neuronal damage and poor outcomes. Therefore, there is an urgent need for disease-modifying therapy (DMT) that targets the pathogenesis of epilepsy. …”
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Study of Brain-derived Neurotrophic Factor in Drug-naive Patients with Schizophrenia by Partik Kaur, Virendra Singh Pal, Vijay Niranjan, Varchasvi Mudgal

“…Background and Aim: Brain-derived neurotrophic factor (BDNF) is a widely studied neurotrophin and is said to be involved in the regulation of many neuronal processes, including neurogenesis, neuronal differentiation, maturation, and survival. …”
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White Matter Hyperintensity Load Modulates Brain Morphometry and Brain Connectivity in Healthy Adults: A Neuroplastic Mechanism? by Matteo De Marco, Riccardo Manca, Micaela Mitolo, Annalena Venneri

“…White matter hyperintensities (WMHs) are acquired lesions that accumulate and disrupt neuron-to-neuron connectivity. We tested the associations between WMH load and (1) regional grey matter volumes and (2) functional connectivity of resting-state networks, in a sample of 51 healthy adults. …”
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The Positive Role of Multiplicative Noise in Complete Synchronization of Unidirectionally Coupled Ring with Three Nodes by Yuzhu Xiao, Sufang Tang, Zhongkui Sun

“…In numerical simulations, the Lorenz system, Rössler like system, and Hindmarsh-Rose neuron model are employed to demonstrate the correctness of our theoretical result.…”
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