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Mapping spreading depolarisations after traumatic brain injury: a pilot clinical study protocol
Published 2022-07-01“…Introduction Cortical spreading depolarisation (CSD) is characterised by a near-complete loss of the ionic membrane potential of cortical neurons and glia propagating across the cerebral cortex, which generates a transient suppression of spontaneous neuronal activity. …”
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1262
A Muscle-Specific Rehabilitation Training Method Based on Muscle Activation and the Optimal Load Orientation Concept
Published 2018-01-01“…In this paper, a muscle-specific rehabilitation training method based on the optimal load orientation concept (OLOC) was proposed for patients whose motor neurons are injured, but whose muscles and tendons are intact, to implement high-efficiency resistance training for the shoulder muscles, which is one of the most complex joints in the human body. …”
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1263
Blockade of NR2A-Containing NMDA Receptors Induces Tau Phosphorylation in Rat Hippocampal Slices
Published 2010-01-01“…From a mechanistic perspective, our study revealed that blockade of NR2A-containing receptors influences Tau phosphorylation probably by increasing calcium influx into neurons, which seems to rely on accumulation of new NR1/NR2B receptors in neuronal membranes and could involve the cyclin-dependent kinase 5 pathway.…”
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1264
IGF-1 Restores Visual Cortex Plasticity in Adult Life by Reducing Local GABA Levels
Published 2012-01-01“…Insulin-like growth factor 1 (IGF-1) is a peptide implicated in prenatal and postnatal phases of brain development such as neurogenesis, neuronal differentiation, synaptogenesis, and experience-dependent plasticity. …”
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1265
Dual-Band Power Divider with Wide Suppression Band
Published 2025-02-01“…The proposed neural network has two outputs (S11 and S21), and two hidden layers with eight neurons at each layer. The weights of each neuron are obtained using particle swarm optimization algorithms. …”
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1266
Investigation of ANN Model Containing One Hidden Layer for Predicting Compressive Strength of Concrete with Blast-Furnace Slag and Fly Ash
Published 2021-01-01“…The ANN models with one hidden layer containing 13 neuron number cases are proposed to determine the best ANN structure. …”
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1267
Gallic acid showed neuroprotection against endoplasmic reticulum stress in rats
Published 2025-01-01“…Gallic acid treatment resulted in a marked reduction in caspase-12 expression in neurons, neuroglia, and endothelial cells, suggesting decreased ER stress. …”
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1268
Novel insights into the study of goblet cell hypersecretion in allergic rhinitis
Published 2025-01-01“…Thus, although previously less recognised, the neuron–goblet cell signalling axis plays a critical role in allergic rhinitis mucus secretion. …”
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1269
Transplanted Adult Neural Stem Cells Express Sonic Hedgehog In Vivo and Suppress White Matter Neuroinflammation after Experimental Traumatic Brain Injury
Published 2017-01-01“…In ShhCreERT2;R26tdTomato mice, Shh was primarily expressed in neurons and was not upregulated in reactive astrocytes or microglia after TBI. …”
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1270
Exploring the Potential of Neural Networks to Predict Statistics of Solar Wind Turbulence
Published 2022-09-01“…A small feedforward ANN, with only 20 hidden neurons, can predict the large‐scale fluctuation amplitudes better than mean imputation or linear interpolation when the percentage of missing data is high. …”
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1271
From light sensing to adaptive learning: hafnium diselenide reconfigurable memcapacitive devices in neuromorphic computing
Published 2025-01-01“…Although charge-based or emerging memory technologies such as memristors have been developed to emulate synaptic plasticity, replicating the key functionality of neurons—integrating diverse presynaptic inputs to fire electrical impulses—has remained challenging. …”
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1272
Comparison between cortical and subcortical diaphragmatic motor stimulation by transcranial magnetic stimulation on patients with chronic obstructive pulmonary disease
Published 2025-02-01“…Abstract Background Transcranial magnetic stimulation (TMS), a non-invasive method of electrically stimulating neurons in the cerebral cortex, can change neuronal and cortical activity locally and remotely by applying localized magnetic fields. …”
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1273
Optimizing Cutting Conditions and Prediction of Surface Roughness in Face Milling of AZ61 Using Regression Analysis and Artificial Neural Network
Published 2017-01-01“…Five models of neural network were developed and the model that showed best fit with experimental results was with 6 neurons in the hidden layer. Regression analysis was also used to build a mathematical model representing the surface roughness as a function of the process parameters. …”
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1274
Elevated Glucose and Interleukin-1β Differentially Affect Retinal Microglial Cell Proliferation
Published 2017-01-01“…In retinal neural cell cultures, we found that IL-1β and IL-1RI are present in microglia, macroglia, and neurons. Exposure of retinal neural cell cultures to high glucose upregulated both mRNA and protein levels of IL-1β. …”
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1275
Neuroprotective Effects of Bone Marrow Mesenchymal Stem Cells on Bilateral Common Carotid Arteries Occlusion Model of Cerebral Ischemia in Rat
Published 2016-01-01“…Ischemia-reperfusion for 30 min causes damage and extensive neuronal death in the hippocampus, especially in CA1 and CA3 regions, leading to several functional and neurological deficits. …”
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1276
Peripheral huntingtin silencing does not ameliorate central signs of disease in the B6.HttQ111/+ mouse model of Huntington's disease.
Published 2017-01-01“…Huntington's disease (HD) is an autosomal dominant neurodegenerative disease whose predominant neuropathological signature is the selective loss of medium spiny neurons in the striatum. Despite this selective neuropathology, the mutant protein (huntingtin) is found in virtually every cell so far studied, and, consequently, phenotypes are observed in a wide range of organ systems both inside and outside the central nervous system. …”
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1277
A Case of John Cunningham Virus Induced Rhombencephalitis after Rituximab Therapy for Idiopathic Thrombocytopenic Purpura
Published 2021-01-01“…Rarely, it may also present as granule cell neuronopathy (GCN), leading to degeneration of cerebellar granule cell neurons. It is described in patients with underlying conditions or medication contributing to immune compromise. …”
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1278
Cochlear Synaptopathy and Noise-Induced Hidden Hearing Loss
Published 2016-01-01“…Disruption of these synapses not only disables the innervated ANFs but also results in the slow degeneration of spiral ganglion neurons if the synapses are not reestablished. Such a loss of ANFs should result in signal coding deficits, which are exacerbated by the bias of the damage toward synapses connecting low-spontaneous-rate (SR) ANFs, which are known to be vital for signal coding in noisy background. …”
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Effects of ketamine and propofol on muscarinic plateau potentials in rat neocortical pyramidal cells.
Published 2025-01-01“…Most previous in vitro studies of cellular mechanisms of anaesthetics have used brain slices or neurons in a nearly "comatose" state, because no "arousing" neuromodulators were added. …”
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1280
Neuroprotective Effect of Intrastriatal Caffeic Acid Phenethyl Ester Treatment in 6-OH Dopamine Model of Parkinson’s Disease in Rats
Published 2021-01-01“…Our results for the first time showed that, besides improving the motor performance, CAPE treatment also prevents 6-OHDA-induced loss of TH-positive neurons. From our results, CAPE may be a promising clinical agent in the treatment of PD.…”
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