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VAPB/ALS8 MSP ligands regulate striated muscle energy metabolism critical for adult survival in caenorhabditis elegans.
Published 2013-01-01“…Mutations in VAPB/ALS8 are associated with amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy (SMA), two motor neuron diseases that often include alterations in energy metabolism. …”
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1202
Development of Microneedle Patch Loaded with Bacopa monnieri Solid Lipid Nanoparticles for the Effective Management of Parkinson’s Disease
Published 2022-01-01“…Herbal products for PD have been shown to have antioxidant effects in reducing dopaminergic neurons from degeneration. Here, we attempted to incorporate solid lipid nanoparticles (SLNs) of Bacopa monnieri into dissolvable microneedle arrays and evaluate its neuroprotective activity. …”
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1203
Too Aggressive Drop in Blood Pressure in a Hypertensive Male Leading to “Man-in-the-Barrel Syndrome”
Published 2020-01-01“…It has been described in various neuropathological conditions affecting the cerebral hemispheres, pons, upper spinal cord, and peripheral neurons. Severe hypotension leading to watershed infarctions leading to this phenotype has been reported. …”
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1204
A Proposed Role for Lymphatic Supermicrosurgery in the Management of Alzheimer's Disease: A Primer for Reconstructive Microsurgeons
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1205
The effect of culture media and seeding densities on the human malignant testicular germ cell line (NT2/D1) growth pattern
Published 2025-02-01“…The NT2/D1 cell line, a pluripotent embryonal carcinoma, is valuable in cancer and developmental biology research due to its differentiation potential into neurons and glial cells. Although Fetal Bovine Serum (FBS) is often used to promote cell growth, its limitations necessitate optimized culture conditions. …”
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1206
Pancreatic organogenesis mapped through space and time
Published 2025-01-01“…Signals from the mesenchyme, neurons, and endothelial cells instruct epithelial cell differentiation during pancreatic development. …”
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1207
A Case of Xanthoma of Bilateral Tendoachilles Reconstructed with Fascia Lata Graft X
Published 2024-01-01“…Deposition of cholestanol in the neurons causes atrophy and secondary demyelination. …”
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1208
Unique ultrastructural organization of human rod photoreceptors
Published 2025-01-01“…Abstract Rod and cone photoreceptor cells are specialized neurons responsible for transforming the information reaching the eyes in the form of photons into the language of neuronal activity. …”
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1209
T-2 toxin induces senescence in human neuroblastoma SH-SY5Y cells by regulating the HIF-1α/p53/p21 pathway
Published 2025-01-01“…The mechanisms by which T-2 toxin induces senescence in neurons, along with the involvement of hypoxia-inducible factor-1α (HIF-1α), remain poorly understood. …”
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1210
High-fat diet and neuroinflammation: The role of mitochondria
Published 2025-02-01“…More importantly, mitochondrial damage, neuroinflammation, and insulin resistance caused by HFD form a mutually reinforcing vicious cycle, ultimately leading to the death of neurons and promoting the progression of neurodegenerative diseases. …”
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1211
Differential Susceptibility to Propofol and Ketamine in Primary Cultures of Young and Senesced Astrocytes
Published 2024-01-01“…Previously, mechanistic and pathogenic investigations focused on neurons, and little is known about the effect of commonly used intravenous anesthetics such as propofol and ketamine on astrocytes. …”
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1212
Gamma Oscillations Facilitate Effective Learning in Excitatory-Inhibitory Balanced Neural Circuits
Published 2021-01-01“…We study an excitatory-inhibitory (E-I) integrate-and-fire neuronal network with triplet STDP, heterosynaptic plasticity, and a transmitter-induced plasticity. …”
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1213
Adrenomedullin as a Growth and Cell Fate Regulatory Factor for Adult Neural Stem Cells
Published 2012-01-01“…AM regulates the proliferation rate and the differentiation into neurons, astrocytes, and oligodendrocytes of stem/progenitor cells, probably through the PI3K/Akt pathway. …”
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1214
Idiopathic Intracranial Hypertension Papillopathy due to Hormonal Changes during Pregnancy
Published 2023-01-01“…Recent research revealed that, during pregnancy, hormones interact with the central nervous system, leading to an increase in the size of neurons which could potentially result in intracranial hypertension. …”
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1215
Ruminal Acidosis in Feedlot: From Aetiology to Prevention
Published 2014-01-01“…Animals will show ruminal hypotony/atony with hydrorumen and a typical parakeratosis-rumenitis liver abscess complex, associated with a plethora of systemic manifestations such as diarrhea and dehydration, liver abscesses, infections of the lung, the heart, and/or the kidney, and laminitis, as well as neurologic symptoms due to both cerebrocortical necrosis and the direct effect of D-lactate on neurons. In feedlots, warning signs include decrease in chewing activity, weight, and dry matter intake and increase in laminitis and diarrhea prevalence. …”
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1216
Artificial neural network forecast application for fine particulate matter concentration using meteorological data
Published 2017-09-01“…The results indicate that the network with hidden layer including six neurons at training epoch 113, has the best performance with the lowest error value (MSE=0.049438) on considering PM2.5 concentrations across metropolitan areas in Tehran. …”
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1217
Water quality assessment for aquaculture using deep neural network
Published 2025-01-01“…In this paper, optimal DNN model is developed by tuning the various parameters like number of hidden layers, hidden neurons and activation functions using Python programme in visual studio. …”
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1218
Cannabis oil in treating Parkinson’s disease: improvement of motor and non-motor symptoms: a case report
Published 2025-01-01“…Abstract Parkinson’s disease (PD) is characterized by progressive loss of dopaminergic neurons in the substantia nigra pars compacta, which leads to a reduction in the production of dopamine. …”
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1219
A high-protein diet-responsive gut hormone regulates behavioral and metabolic optimization in Drosophila melanogaster
Published 2024-12-01“…Gut-derived CCHa1 is received by a small subset of enteric neurons that produce short neuropeptide F, thereby modulating protein-specific satiety. …”
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1220
Medical foods in Alzheimer’s disease
Published 2019-03-01“…Improvements in symptomatology and regional brain atrophy in AD have been claimed for several medical foods, for example, those providing ketone bodies as alternative energy supply to neurons, those containing precursors believed to improve synaptic function, and those addressing oxidative stress related to memory loss. …”
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