Periodontal Health and Caries Prevalence Evaluation in Patients Affected by Parkinson's Disease by Marco Cicciù, Giacomo Risitano, Giuseppe Lo Giudice, Ennio Bramanti

“…Parkinson's disease (PD) is a progressive neurodegenerative disorder related to the loss or absence of dopaminergic neurons in the brain. These deficits result in slowness of movement, tremor, rigidity, and dysfunction of behaviour. …”
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NaHS modulates astrocytic EAAT2 expression to impact SNI-induced neuropathic pain and depressive-like behaviors by Man-Man Qi, Heng-Yue Peng, Tian-Ge Zhang, Yan Li, Meng-Ya Gao, Wen-Bo Sun, Xu-Peng Wang

“…The study further demonstrates NaHS’s potential in reducing glutamate levels in the spinal cord and the discharge frequency of neurons in the primary somatosensory cortex hindlimb region (S1HL) brain area, suggesting a novel therapeutic approach for neuropathic pain through the modulation of astrocyte function and EAAT2 expression.…”
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ROLE OF THE MODULATORY MEDIATOR SEROTONIN IN THE INDUCTION OF EPIGENETIC PROCESSES DURING LONG TERM MEMORY FORMATION IN HELIX by L. N. Grinkevich, O. V. Vorobiova

“…Mollusks are a popular model in neurobiology, because they have relatively simple CNSs with giant neurons. Previously, we found strong induction of histone H3 acetylation and methylation during food aversion conditioning in Helix. …”
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Spinal NGF Restores Opioid Sensitivity in Neuropathic Rats: Possible Role of NGF as a Regulator of CCK-Induced Anti-Opioid Effects by Catherine M Cahill, Terence J Coderre

“…The authors hypothesize that NGF is critical in maintaining neurochemical homeostasis in the spinal cord of nociceptive neurons, and that supplementation may be beneficial in restoring and/or maintaining opioid analgesia in chronic pain conditions resulting from traumatic nerve injury.…”
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Simulation and accurate prediction of thermal efficiency of functionalized COOH-MWCNT/water nanofluids by artificial neural network using experimental data by Mohammad Hemmat Esfe, Davood Toghraie, Saeed Esfandeh, Sayyid Majid Motallebi

“…To model this data, an ANN with two hidden layers with 7 and 8 neurons in the first and second layers, respectively, is used. …”
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Transcendence: what on earth are we talking about? by Daniël P. Veldsman

“…Songs are more than longitudinal sound vibrations, sunsets more than transverse electromagnetic oscillations, inspirations more than the discharge of neurons, all touched with a mystery that deepens the more we contemplate and seek to understand (Harrison 1985: 273). …”
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Regeneration of Zebrafish CNS: Adult Neurogenesis by Sukla Ghosh, Subhra Prakash Hui

“…Injury induced proliferation involves radial glia which proliferate, transcribe embryonic genes, and can give rise to new neurons. Recent technological development of exquisite molecular tools in zebrafish, such as cell ablation, lineage analysis, and novel and substantial microarray, together with advancement in stem cell biology, allowed us to investigate how progenitor cells contribute to the generation of appropriate structures and various underlying mechanisms like reprogramming.…”
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HCNetlas: A reference database of human cell type-specific gene networks to aid disease genetic analyses. by Jiwon Yu, Junha Cha, Geon Koh, Insuk Lee

“…These methods find that systemic lupus erythematosus genes predominantly function in myeloid cells, and Alzheimer's disease genes mainly play roles in inhibitory and excitatory neurons. Additionally, they suggest that many lung cancer-related genes may exert their roles in immune cells. …”
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Effects of Methamphetamine on Single Unit Activity in Rat Medial Prefrontal Cortex In Vivo by Jinhwa Jang, Hee-Jin Ha, Yun Bok Kim, Young-Ki Chung, Min Whan Jung

“…To investigate how neuronal activity in the prefrontal cortex changes in an animal model of schizophrenia, we recorded single unit activity in the medial prefrontal cortex of urethane-anesthetized and awake rats following methamphetamine (MA) administration. …”
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Mitochondrial Dysfunction and α-Synuclein Synaptic Pathology in Parkinson’s Disease: Who’s on First? by Michela Zaltieri, Francesca Longhena, Marina Pizzi, Cristina Missale, PierFranco Spano, Arianna Bellucci

“…Its characteristic neuropathological features encompass the loss of dopaminergic neurons of the nigrostriatal system and the presence of Lewy bodies and Lewy neurites. …”
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The Role of Dopamine in Impulsivity and Substance Abuse: A Narrative Review by Connor J Plaisance, Lloyd F Ledet III, Nicholas J Slusher, Charles P Daniel, Zachary Lee, Bradley Dorius, Sonnah Barrie, Tomasina Q Parker-Actlis, Shahab Ahmadzadeh, Sahar Shekoohi, Alan D Kaye

“…It is well established that most of the dopaminergic neurons of the brain are located in the ventral mid-brain and consists of four main pathways: mesocortical, mesolimbic, nigrostriatal, and tuberoinfundibular pathways. …”
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A high‐capacity and nonvolatile spintronic associative memory hardware accelerator by Mahan Rezaei, Abdolah Amirany, Mohammad Hossein Moaiyeri, Kian Jafari

“…A nonvolatile associative memory based on spintronic synapses utilising magnetic tunnel junction (MTJ) and carbon nanotube field‐effect transistors (CNTFET)‐based neurons is proposed. The proposed design uses the MTJ device because of its fascinating features, such as reliable reconfiguration and nonvolatility. …”
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Management of Ocular Diseases Using Lutein and Zeaxanthin: What Have We Learned from Experimental Animal Studies? by Chunyan Xue, Richard Rosen, Adrienne Jordan, Dan-Ning Hu

“…In these animal models, lutein and zeaxanthin have been reported to have beneficial effects in protecting ocular tissues and cells (especially the retinal neurons) against damage caused by different etiological factors. …”
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Lactoferrin alleviates the adverse effects of early-life inflammation on depression in adults by regulating the activation of microglia by Wenli Wang, Qin An, Yunxia Zou, Yunping Dai, Qingyong Meng, Yali Zhang

“…In contrast, recombinant human lactoferrin promotes neuronal proliferation by upregulating ERK 1 and 2 phosphorylation and attenuates LPS-induced neuronal injury and microglial activation by inhibiting the activation of Toll-like receptor 4—nuclear factor-kappa B pathway in vitro. …”
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Stem Cells as In Vitro Model of Parkinson's Disease by Patricia L. Martínez-Morales, Isabel Liste

“…In addition, the lack of an adequate in vitro human neuron cell-based model has been an obstacle for the uncover of new drugs for treating PD. …”
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Could Cells from Your Nose Fix Your Heart? Transplantation of Olfactory Stem Cells in a Rat Model of Cardiac Infarction by Cameron McDonald, Alan Mackay-Sim, Denis Crane, Wayne Murrell

“…Neural stem cells from the olfactory mucosa are multipotent, with the capacity to differentiate into developmental fates other than neurons and glia, with evidence of cardiomyocyte differentiation in vitro and after transplantation into the chick embryo. …”
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Unraveling cerebroprotective potential of fenchone: A combined in vivo and in silico exploration of nitric oxide synthase modulation by Bangaru Mamatha, Anka Rao Areti, DSNBK Prasanth, Narender Malothu

“…Histological analysis further corroborated the neuroprotective effects of FEN, demonstrating the structural preservation of neurons in the hippocampal CA1 region. Overall, the results suggest that FEN plays a neuroprotective role in brain ischemia, potentially through the inhibition of NOS, reduction of oxidative stress, and modulation of antioxidants, highlighting the potential of FEN as a therapeutic candidate for ischemic stroke management.…”
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Phosphodiesterase 4 inhibition as a novel treatment for stroke by Jiahong Zhong, Xihui Yu, Zhuomiao Lin

“…These mechanisms collectively facilitate the recovery of functional neurons, thereby serving as potential therapeutic interventions. …”
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Augmentation of Tonic GABAA Inhibition in Absence Epilepsy: Therapeutic Value of Inverse Agonists at Extrasynaptic GABAA Receptors by Adam C. Errington, David W. Cope, Vincenzo Crunelli

“…It is well established that impaired GABAergic inhibition within neuronal networks can lead to hypersynchronous firing patterns that are the typical cellular hallmark of convulsive epileptic seizures. …”
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VMAT2-Deficient Mice Display Nigral and Extranigral Pathology and Motor and Nonmotor Symptoms of Parkinson's Disease by Tonya N. Taylor, W. Michael Caudle, Gary W. Miller

“…Disruption of dopamine storage has been hypothesized to damage the dopamine neurons that are lost in Parkinson's disease. By disrupting vesicular storage of dopamine and other monoamines, we have created a progressive mouse model of PD that exhibits catecholamine neuron loss in the substantia nigra pars compacta and locus coeruleus and motor and nonmotor symptoms. …”
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