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1121
Absence of Rybp Compromises Neural Differentiation of Embryonic Stem Cells
Published 2016-01-01“…We found that rybp null mutant ESCs formed less matured neurons, astrocytes, and oligodendrocytes from existing progenitors than wild type cells. …”
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1122
Dynamic tracking of objects in the macaque dorsomedial frontal cortex
Published 2025-01-01“…We test the mental simulation hypothesis by combining a naturalistic ball-interception task, large-scale electrophysiology in non-human primates, and recurrent neural network modeling. We find that neurons in the monkeys’ dorsomedial frontal cortex (DMFC) represent task-relevant information about the ball position in a multiplexed fashion. …”
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1123
The Angiotensin II Type 2 Receptor in Brain Functions: An Update
Published 2012-01-01“…If confirmed, these new pharmacological tools should help to improve impaired cognitive performance, not only through its action on brain microcirculation and inflammation, but also through more specific effects on neurons. However, the overall physiological relevance of the AT2 receptor in the brain must also consider the Ang IV/AT4 receptor.…”
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1124
Utilizing the Novel Developed MLP Techniques to Survey Pile Subsidence via Optimization Algorithms
Published 2022-10-01“…This research aims to develop the Multilayer Perceptron coupled with the Novel Arithmetic Optimization Algorithm and Biogeography-Based Optimization) to find out the optimal number of hidden layers of neurons within MLP. The Klang Valley Mass Rapid Transit network built in Kuala Lumpur, Malaysia, was chosen to test the piles' settlement and earth properties algorithms. …”
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1125
The Role of Glial Cells in the Pathophysiology of Epilepsy
Published 2025-01-01“…Understanding the dynamic interactions of glial cells with neurons provides promising avenues for novel epilepsy therapies. …”
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1126
The Δ33-35 Mutant α-Domain Containing β-Domain-Like M3S9 Cluster Exhibits the Function of α-Domain with M4S11 Cluster in Human Growth Inhibitory Factor
Published 2010-01-01“…Neuronal growth inhibitory factor (GIF), also known as metallothionein (metallothionein-3), impairs the survival and neurite formation of cultured neurons. …”
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1127
Therapeutic Potential of 5-HT2C Receptor Ligands
Published 2010-01-01“…In addition, their expression in specific neuronal populations in the hypothalamus would be critical for their role in the regulation of feeding behavior. …”
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1128
Outcomes of dietary interventions in the prevention and progression of Parkinson's disease: A literature review
Published 2024-12-01“…Factors contributing to this neuronal degeneration include mitochondrial dysfunction, oxidative stress, and neuronal excitotoxicity. …”
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1129
Mixed Stimulus-Induced Mode Selection in Neural Activity Driven by High and Low Frequency Current under Electromagnetic Radiation
Published 2017-01-01“…The electrical activities of neurons are dependent on the complex electrophysiological condition in neuronal system, the three-variable Hindmarsh-Rose (HR) neuron model is improved to describe the dynamical behaviors of neuronal activities with electromagnetic induction being considered, and the mode transition of electrical activities in neuron is detected when external electromagnetic radiation is imposed on the neuron. …”
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1130
Nucleolar PARP-1 Expression Is Decreased in Alzheimer’s Disease: Consequences for Epigenetic Regulation of rDNA and Cognition
Published 2016-01-01“…Nucleolar PARP-1 staining ranged from dispersed and less intense to entirely absent in AD compared to the distinct nucleolar localization in hippocampal pyramidal neurons in controls. In cases of AD, the percentage of hippocampal pyramidal cells with nucleoli that were positive for both PARP-1 and the nucleolar marker fibrillarin was significantly lower than in controls. …”
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1131
Axon regeneration: an issue of translation
Published 2024-12-01“…In the mammalian central nervous system (CNS), adult neurons fail to regenerate spontaneously upon axon injury, which leads to a permanent and irreversible loss of neuronal functions. …”
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1132
Approaches to the Modulation of Abdominal Pain
Published 1999-01-01“…Even though the precise mechanisms and sites underlying these alterations remain incompletely understood, plausible targets for the development of effective pharmacological treatments are receptors on peripheral terminals of visceral afferent nerves (opioids and serotonin), ion channels and receptors on dorsal horn neurons within the spinal cord (opioids, glutamate, calcitonin gene-related peptide and neurokinin-1), and supraspinal targets in the brainstem within the limbic system and in the prefrontal cortex (serotonin, catecholamines, dopamine and acetylcholine). …”
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1133
Radial and Sigmoid Basis Function Neural Networks in Wireless Sensor Routing Topology Control in Underground Mine Rescue Operation Based on Particle Swarm Optimization
Published 2013-09-01“…Particle swarm optimisation with adaptive mutation was used to train the neurons. Computer simulation results showed that the neural network learning algorithm minimized the error between the neural network output and the desired output such that final error values were either the same as the error goal or less than the error goal. …”
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1134
STRUCTURAL AND DYNAMIC PROPERTIES OF MUTANTS OF THE SOD1 PROTEIN ASSOCIATED WITH AMYOTROPHIC LATERAL SCLEROSIS
Published 2015-01-01“…Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease, which affects motor neurons in the brain and spinal cord and leads to patients’ death. …”
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1135
Complex Form Variant of Dysembryoplastic Neuroepithelial Tumor of the Cerebellum
Published 2012-01-01“…These neurocytic areas showed an eosinophilic matrix forming microcysts, and cells with aspect of “floating neurons” were occasionally identified. A complex form variant of DNT was diagnosed. …”
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1136
Studying Cortical Plasticity in Ophthalmic and Neurological Disorders: From Stimulus-Driven to Cortical Circuitry Modeling Approaches
Published 2019-01-01“…Unsolved questions in computational visual neuroscience research are whether and how neurons and their connecting cortical networks can adapt when normal vision is compromised by a neurodevelopmental disorder or damage to the visual system. …”
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1137
Paired Stimulation to Promote Lasting Augmentation of Corticospinal Circuits
Published 2016-01-01“…The first uses principles of Hebbian plasticity: by altering the stimulation timing of presynaptic neurons and their postsynaptic targets, synapse function can be modulated up or down. …”
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1138
Transcranial Alternating Current and Random Noise Stimulation: Possible Mechanisms
Published 2016-01-01“…Animal experiments have demonstrated in what way neurons react to invasively and transcranially applied alternating currents. …”
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1139
Hsp70 and Its Molecular Role in Nervous System Diseases
Published 2011-01-01“…Hsp70 functions as a chaperone and protects neurons from protein aggregation and toxicity (Parkinson disease, Alzheimer disease, polyglutamine diseases, and amyotrophic lateral sclerosis), protects cells from apoptosis (Parkinson disease), is a stress marker (temporal lobe epilepsy), protects cells from inflammation (cerebral ischemic injury), has an adjuvant role in antigen presentation and is involved in the immune response in autoimmune disease (multiple sclerosis). …”
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1140
Prediction of PM2.5 via precursor method using meteorological parameters
Published 2025-02-01“…The model consists of an input layer with four input variables, a hidden layer with 10 neurons, and an output layer consisting of PM2.5. …”
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