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1041
Malware detection approach based on improved SOINN
Published 2019-12-01“…To deal with the problems of dynamic update of detection model and high computation costs in malware detection model based on batch learning,a novel malware detection approach is proposed by combing SOINN and supervised classifiers,to reduce computation costs and enable the detection model to update dynamically with the assistance of SOINN′s incremental learning characteristic.Firstly,the improved SOINN was given.According to the whole alignment algorithm,search the adjusted weights of neurons under all input sequences in the learning cycle and then calculate the average value of all adjusted weights as the final result,to avoid SOINN′s stability under different input sequences and representativeness of original data,therefore improve malware detection accuracy.Then a data preprocessing algorithm was proposed based on nonnegative matrix factor and Z-score normalization to transfer the malware behavior feature vector from high dimension and high order to low dimension and low order,to speed up and avoid overfitting and further improve detection accuracy.The results of experiments show that proposed approach supports dynamic updating of detection model and has a significantly higher accuracy of detecting unknown new samples and lower computation costs than tradition methods.…”
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1042
Acquisition of similar properties by filters in the same stream of a multistream convolutional neural network
Published 2025-01-01“…In the visual cortex of primates, adjacent neurons often respond to the same visual submodality, such as color or orientation, and have a similar preferred orientation or preferred color. …”
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1043
Meningiomatosis Restricted to the Left Cerebral Hemisphere Presenting with Frontal Lobe Seizure: A Short Communication
Published 2024-12-01“…Although seizures are cortical phenomena that typically originate from lesions affecting cortical neurons, meningiomas, which arise from the meningeal lining, can still induce seizures due to their proximity to the cerebral cortex. …”
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1044
Effects of Various Flavonoids on the α-Synuclein Fibrillation Process
Published 2010-01-01“…α-Synuclein aggregation and fibrillation are closely associated with the formation of Lewy bodies in neurons and are implicated in the causative pathogenesis of Parkinson's disease and other synucleinopathies. …”
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1045
Olfactory dysfunction as potential biomarker in neurodegenerative diseases: a narrative review
Published 2025-01-01“…Neurodegenerative diseases represent a group of disorders characterized by progressive degeneration of neurons in the central nervous system, leading to a range of cognitive, motor, and sensory impairments. …”
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1046
A Green AI Methodology Based on Persistent Homology for Compressing BERT
Published 2025-01-01“…Consequently, PBCE can simplify the BERT model by providing explainability to its neurons and reducing the model’s size, making it more suitable for deployment on resource-constrained devices.…”
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1047
Emergence of Prediction by Reinforcement Learning Using a Recurrent Neural Network
Published 2010-01-01“…In a task where an agent gets a reward when it catches a moving object that can possibly become invisible, it was observed that the agent learned to detect the necessary factors of the object velocity before it disappeared, to relay the information among some hidden neurons, and finally to catch the object at an appropriate position and timing, considering the effects of bounces off a wall after the object became invisible.…”
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1048
Conserved multisensory integration of social cues in the thalamus
Published 2025-01-01“…These inputs are mostly processed in the mammalian colliculi and homologous structures in other vertebrates and are subsequently integrated in the posterior thalamus. Increased neuronal activity in this area promotes pro-social behavior across vertebrates. …”
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1049
VCP regulates early tau seed amplification via specific cofactors
Published 2025-01-01“…We used immortalized cells and human neurons to study the effects of VCP on tau seeding. …”
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1050
Electroacupuncture alleviates paclitaxel-induced peripheral neuropathy by reducing CCL2-mediated macrophage infiltration in sensory ganglia and sciatic nerve
Published 2025-01-01“…EA ameliorated other signs of PIPN, including sensory neuron damage, sciatic nerve morphology impairment and IENFs loss. …”
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1051
Direct engulfment of synapses by overactivated microglia due to cadmium exposure and the protective role of Nrf2
Published 2025-01-01“…Finally, we developed co-culture systems of either Nrf2-KD or Scramble microglia and primary neurons or HT22 neurons to study the effects of Nrf2-regulated microglial activation on synaptic damages induced by Cd. …”
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1052
Exome sequencing reveals a rare damaging variant in GRIN2C in familial late-onset Alzheimer's disease
Published 2025-01-01“…Functional analysis was performed using primary neuronal cultures, and the impact of the variant was assessed through immunocytochemistry and electrophysiology. …”
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1053
Corticostriatal maldevelopment in the R6/2 mouse model of juvenile Huntington's disease
Published 2025-01-01“…In striatal medium-sized spiny neurons (MSNs), a different picture emerged. Intrinsic membrane properties were relatively normal throughout development, except for a transient increase in membrane capacitance at P14. …”
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1054
The Fractured Self: Exploring Selfhood in the Neuronovel The Echo Maker and the Neuromemoir Brain on Fire
Published 2021-12-01“…While the result of the connections of millions of neurons is a smooth and linear perception of the self and the world around us, neuronarratives can complicate this process by revealing the divisions and occasional contradictions that occur in the combination.…”
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1055
DYRK1A (Dual-Specificity Tyrosine-Phosphorylated and -Regulated Kinase 1A): A Gene with Dosage Effect During Development and Neurogenesis
Published 2006-01-01“…The research in the last years suggests a relevant conserved function during neuronal development, related to proliferation and/or differentiation for DYRK1A. …”
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1056
Is Parkinson’s Disease Truly a Prion-Like Disorder? An Appraisal of Current Evidence
Published 2015-01-01“…Characterised by a loss of dopaminergic neurons and the development of intraneuronal inclusions known as Lewy bodies, it has classically been thought of as a cell-autonomous disease. …”
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1057
Poor fixation stability does not account for motion perception deficits in amblyopia
Published 2025-01-01“…It is possible that poor fixation stability during motion viewing interferes with the fidelity of the input to motion-sensitive neurons in visual cortex. To probe these mechanisms at a behavioral level, we assessed motion coherence thresholds in adults with amblyopia while measuring fixation stability. …”
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1058
Novel insights into mechanisms and therapeutics for presbycusis
Published 2025-01-01“…Irreversible hearing loss occurs due to the limited regenerative capacity of spiral neurons and peripheral cochlear hair cells (HCs). …”
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1059
Viruses and neurodegeneration: a growing concern
Published 2025-01-01“…Abstract Neurodegenerative diseases (NDDs) cause a progressive loss of neurons. Since NDDs are multifactorial, the precise etiology varies on the basis of the type of disease and patient history. …”
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1060
Family case of cardiac achalasia
Published 2014-10-01“…Cardiac achalasia is idiopathic disease, caused by inflammation and degeneration of myenteric plexus resulting in loss of postganglionic inhibitory neurons, essential for relaxation of the lower esophageal sphincter and peristaltic contractions of the esophagus. …”
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